Avery D Posey, PhD

faculty photo
Assistant Professor of Pharmacology
Instructor, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine
Research Health Specialist, Corporal Michael J. Crescenz VA Medical Center
Director, Diversity and Inclusion, Center for Cellular Immunotherapy, Perelman School of Medicine, University of Pennsylvania
Department: Pharmacology
Graduate Group Affiliations

Contact information
PCAM SPE 8-106
3400 Civic Center Blvd.
Philadelphia, PA 19104
Education:
B.S. (Bioinformatics and Computational Biology)
University of Maryland, Baltimore County (UMBC), Baltimore, MD, 2005.
B.S. (Biochemistry and Molecular Biology)
University of Maryland, Baltimore County (UMBC), Baltimore, MD, 2005.
PhD (Genetics)
The University of Chicago, Chicago, IL, 2011.
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Selected Publications

Derosiers N, Aguilar W, DeGaramo DA, Posey AD Jr.: Sweet Immune Checkpoint Targets to Enhance T Cell Therapy. J Immunol 208: 278-285, Jan 2022.

Ferguson ID, Patino-Escobar B, Tuomivaara ST, Lin YT, Nix MA, Leung KK, Kasap C, Ramos E, Vasquez WN, Talbot A, Hale M, Naik A, Kishishita A, Choudhry P, Lopez-Girona A, Miao W, Wong SW, Wolf JL, Martin TG III, Shah N, Vandenberg S, Prakash S, Besse L, Driessen C, Posey AD Jr., Mullins RD, Eyquem J, Wells JA, and Wiita AP: The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance. Nature Communications 2022.

Keane JT, Posey AD Jr.: Chimeric Antigen Receptors Expand the Repertoire of Antigenic Macromolecules for Cellular Immunity. Cells 10: 3356, Nov 2021.

Bear AS, Blanchard T, Cesare J, Ford MJ, Richman LP, Xu C, Baroja ML, McCuaig S, Costeas C, Gabunia K, Scholler J, Posey AD Jr, O'Hara MH, Smole A, Powell DJ Jr, Garcia BA, Vonderheide RH, Linette GP, Carreno BM.: Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting. Nat Commun 12: 4365, Jul 2021.

Douglas, B., Oyesola, O., Cooper, M.M., Posey, A., Tait Wojno, E., Giacomin, P.R., Herbert, D.R.: Immune System Investigation Using Parasitic Helminths. Annu Rev Immunol 39: 639-665, Apr 2021.

Annabi, N., Baker, M., Boettiger, A., Chakraborty, D., Chen, Y., Corbett, K.S., Correia, B., Dahlman, J., de Oliviera, T., Ertuerk, A., Yanik, M.F., Henaff, E., Huch, M., Iliev, I.D., Jacobs, T., Junca, H., Keung, A., Kolodkin-Gal, I., Krishnaswamy, S., Lancaster, M., Macosko, E., Martinez-Nunez, M.A., Miura, K., Molloy, J., Cruz, A.O., Platt, R.J., Posey, A.D. Jr., Shao, H., Simunovic, M., Slavov, N., Takebe, T., Vandenberghe, L.H., Varshney, R.K., Wang, J.: Voices of biotech research. Nat Biotechnology Mar 2021.

Wellhausen, N., Aguilar, A., Posey, A.D. Jr.: Glycans as Targets and Mediators of T-Cell Immunotherapy. Comprehensive Glycoscience (Second Edition) 5: 508-518, 2021.

King-Peoples TR, Posey AD Jr.: Splitting signals drives CARs further. Nat Cancer 2021.

Dagher, O., King, T.R., Wellhausen, N., Posey, A.D. Jr.: Combination Therapy for Solid Tumors: Taking a Classic CAR on New Adventures. Cancer Cell 38: 621-623, Nov 2020.

Parker KR, Migliorini D, Perkey E, Yost KE, Bhaduri A, Bagga P, Haris M, Wilson NE, Liu F, Gabunia K, Scholler J, Montine TJ, Bhoj VG, Reddy R, Mohan S, Maillard I, Kriegstein AR, June CH, Chang HY, Posey AD Jr, Satpathy AT.: Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies. Cell 183: 126-142, Oct 2020.

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Last updated: 07/27/2022
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