Shaon Sengupta, MBBS, MPH, FAAP
Assistant Professor of Pediatrics (Neonatology & Newborn Services)
Attending Physician, Neonatal-Perinatal Medicine, Children's Hospital of Philadelphia and Hospital of University of Pennsylvania
Affiliate, Institute of Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania
Department: Pediatrics
Graduate Group Affiliations
Contact information
Children's Hospital of Philadelphia
Abramson Research Center
3615 Curie Blvd
Office: 1102C
Lab 1103
Philadelphia, PA 19104
Abramson Research Center
3615 Curie Blvd
Office: 1102C
Lab 1103
Philadelphia, PA 19104
Office: 267-426-6628
Fax: 215-590-4267
Fax: 215-590-4267
Education:
MBBS
All India Institute of Medical Sciences, India (Medicine and Surgery) , 2006.
MPH
Johns Hopkins Bloomberg School of Public Health (Epidemiology and Statistics), 2008.
Permanent linkMBBS
All India Institute of Medical Sciences, India (Medicine and Surgery) , 2006.
MPH
Johns Hopkins Bloomberg School of Public Health (Epidemiology and Statistics), 2008.
Description of Clinical Expertise
Neonatology, ECMO, NRPDescription of Research Expertise
Circadian biology, Lung inflammation, Neonatal lung injury, Influenza, Lung regeneration, Lung organoidsSelected Publications
KM Forrest, M Towers, O Paul, H Cho, M.V. Padmini, A Naik, HK Lim, Y Issah, H.S Deshmukh, M.C. Abt, KM Hudock, GR. Grant, TG. Brooks, S Sengupta: Role of IL10 signaling in the circadian control of host response to Influenza infection bioRxiv 2025.03.03.641134; doi: https://doi.org/10.1101/2025.03.03.641134 March 2025.O Paul, TG. Brooks, L Assi, A Shetty, M Towers, KM Forrest, A Cameron, A Sehgal, GR. Grant, S Sengupta: Effect of external cues on clock-driven protection from Influenza A infection bioRxiv 2025.03.03.641279; doi: https://doi.org/10.1101/2025.03.03.641279 March 2025.
Brooks TG, Lahens NF, Mrčela A, Yang J, Purohit S, Naik A, Ricciotti E, Sengupta S, Choi PS, Grant GR. : Sources of non-uniform coverage in short-read RNA-Seq data. bioRxiv [Preprint]. 6:2025.01.30.634337. doi: 10.1101/2025.01.30.634337. Feb 2025.
Thomas Brooks , Nicholas Lahens , Antonijo Mrčela , Dimitra Sarantopoulou , Soumyashant Nayak , Amruta Naik , Shaon Sengupta , Peter Choi, G.R. Grant: BEERS2: RNA-Seq simulation through high fidelity in silico modeling. Briefings in Bioinformatics 2024.
Joseph Stevens, Erica Culberson, Jeremy Kinder, Alicia Ramiriqui, Jerilyn Gray, Madeline Bonfield, Tzu-Yu Shao, Faris Al Gharabieh, Laura Peterson, Shelby Steinmeyer, William Zacharias, Gloria Pryhuber, Oindrila Paul, Shaon Sengupta, Theresa Alenghat, Sing Sing Way, Hitesh Deshmukh: Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns bioRxiv .04.09.588427; doi: https://doi.org/10.1101/2024.04.09.588427 2024 Notes: Accepted in March 2025, undergoing editorial processing at Cell.
Naik A, Forrest K, Paul O, Issah Y, Valekunja UK, Tang SY, Reddy AB, Hennessy E, Brooks TS, Chaudhry F, Babu A, Morley M, Zepp JA, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S.: Circadian regulation of lung repair and regeneration JCI Insight Page: e164720. doi: 10.1172/jci.insight.164720. August 2023.
Cox SL, O’Siorain JR, He Y, Lordan R, Naik A, Tang SY, Sengupta S, FitzGerald GA, Carroll RG, Curtis AM.: Circadian disruption in lung fibroblasts enhances NF-κB activity to exacerbate neutrophil recruitment. FASEB J 37(2): e22753 Feb 2023.
Christopher M. Cielo, Janet Lioy, Darko Stefanovski, Shaon Sengupta,, Sagori Mukhopadhyay, Mary Anne Cornaglia, Ignacio E. Tapia: Respiratory indices during sleep in healthy infants: a prospective longitudinal study and metanalysis Sleep Medicine 99(1): 49-57, Nov 2022.
S Sengupta, Y Lee, J Q Tao, A Sehgal and S Chatterjee: Circadian Control of Pulmonary Endothelial Signaling occurs via NADPH oxidase 2-NLRP3 pathway. Bioarchives Page: doi: https://doi.org/10.1101/2022.06.05.493624, June 2022 Notes: online pub.
Theken KN, Tang SY, Sengupta S, FitzGerald GA.2021 : The roles of lipids in SARS-CoV-2 viral replication and the host immune response. J Lipid Res. 62(100129): doi: 10.1016/j.jlr.2021.100129, Sep 2021.