Xiaowei Sherry Liu, PhD

faculty photo
Associate Professor of Orthopaedic Surgery
Director, McKay MicroCT Imaging Core, Department of Orthopaedic Surgery, University of Pennsylvania
Director, MicroCT Imaging Core, Penn Center for Musculoskeletal Disorders
Department: Orthopaedic Surgery
Graduate Group Affiliations

Contact information
McKay Orthopaedic Research Laboratory
332A Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104
Office: 215-746-4668
Fax: 215-573-2133
B.E. (Bioengineering and Instrumentation)
Tsinghua University, 2002.
M.S. (Biomedical Engineering)
Columbia University, 2004.
M. Phil. (Biomedical Engineering)
Columbia University, 2005.
Ph.D. (Biomedical Engineering)
Columbia University, 2007.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Wang L, Tower RJ, Chandra A, Yao L, Tong W, Xiong Z, Tang K, Zhang Y, Liu XS, Boerckel JD, Guo X, Ahn J, and Qin L: Periosteal mesenchymal progenitor dysfunction and extraskeletally-derived fibrosis contribute to atrophic fracture nonunion. Journal of Bone and Mineral Research 34(3): 520-534, 2019.

de Bakker, CMJ, Zhao H, Tseng W-J, Li Y, Altman-Singles AR, Liu Y, Leavitt L, and Liu XS*: Effects of reproduction on sexual dimorphisms in rat bone mechanics. Journal of Biomechanics 77: 40-47, 2018 Notes: * Corresponding author.

Chandra A, Wang L, Young T, Zhong L, Tseng W-J, Levine MA, Cengel K, Liu XS, Zhang Y, Pignolo RJ, and Qin L: Proteasome inhibitor Bortezomib is a novel therapeutic for focal radiation-induced osteoporosis. FASEB Journal 32(1): 52-62, 2018.

de Bakker, CMJ, Li Y, Zhao H, Leavitt L, Tseng W-J, Lin T, Tong W, Qin L, and Liu XS*: Structural adaptations in the rat tibia bone induced by pregnancy and lactation confer protective effects against future estrogen deficiency. Journal of Bone and Mineral Research 33(12): 2165-2176, 2018 Notes: * Corresponding author.

Jia H, Ma X, TongW, Wei Y, Tower R, Chandra A, Sun Z, Yang Z, Badar F, Zhang K, Tseng W-J, Kramer I, Kneissel M, Xia Y, Liu XS, Wang J, Han L, Enomoto-Iwamoto M, and Qin L: Subchondral bone plate sclerosis during late osteoarthritis is caused by loading-induced reduction in Sclerostin amount. Arthritis & Rheumatology 70(2): 230-41, 2018.

Chandra A, Lin T, Young T, Tong W, Ma X, Tseng W-J, Kramer I, Kneissel M, Levine MA, Zhang J, Cengel K, Liu XS, and Qin L: Suppression of Sclerostin alleviates radiation-induced bone loss by protecting bone forming cells and their progenitors through distinct mechanisms. Journal of Bone and Mineral Research 32(2): 360-72, 2017.

Altman-Singles AR, Jeong Y, Tseng W-J, de Bakker CMJ, Zhao H, Lott C, Robberts J, Qin L, Han L, Kim D-G, and Liu XS*: Intermittent parathyroid hormone after prolonged alendronate treatment induces substantial new bone formation and increases bone tissue heterogeneity in ovariectomized rats. Journal of Bone and Mineral Research 32(8): 1703-15, 2017 Notes: *Corresponding author.

de Bakker CMJ, Tseng W-J, Li Y, Zhao H, Altman-Singles AR, Jeong Y, Robberts Y, Han L, Kim D-G, and Liu XS*: Reproduction differentially affects trabecular bone depending on its mechanical vs. metabolic role. Journal of Biomechanical Engineering 139(11), 2017 Notes: * Corresponding author; Journal of Biomechanical Engineering 2017 Editor’s Choice Award.

de Bakker CMJ, Altman-Singles AR, Li Y, Tseng WJ, Li C, and Liu XS*: Adaptations in the microarchitecture and load distribution of maternal cortical and trabecular bone in response to multiple reproductive cycles in rats. Journal of Bone and Mineral Research 32(5): 1014-26, 2017 Notes: * Corresponding author.

Zhou B, Zhang Z, Wang J, Yu YE, Liu XS, Nishiyama KK, Rubin MR, Shane E, Bilezikian JP, Guo XE: In vivo precision of digital topological skeletonization based individual trabecula segmentation (ITS) analysis of trabecular microstructure at the distal radius and tibia by HR-pQCT. Pattern Recognition Letters 76: 83-9, 2016.

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Last updated: 10/25/2019
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