Laura Vella, M.D., Ph.D.

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
3615 Civic Center Blvd.
Philadelphia, PA 19104
Education:
BA (Major: Biology, Minor: English)
University of Delaware, 2002.
PhD (Immunology)
University of Pittsburgh School of Medicine, 2008.
MD
University of Pittsburgh School of Medicine, 2010.
MSTR (Translational Research)
University of Pennsylvania, 2019.
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Selected Publications

Vella LA#*, Giles JR*, Baxter AE*, Oldridge DA*, Diorio C, Kuri-Cervantes L, Alanio C, Pampena MB, Wu JE, Chen Z, Huang YJ, Anderson EM, Gouma S, McNerney KO, Chase J, Burudpakdee C, Lee JH, Apostolidis SA, Huang AC, Mathew S, Kuthuru O, Goodwin EC, Weirick ME, Bolton MJ, Arevalo CP, Ramos A, Jasen C, Giannini HM, D’Andrea K, The UPenn COVID Processing Unit, Meyer MJ, Behrens EM, Bassiri H, Hensley SE, Henrickson SE, Teachey DT, Betts MR, Wherry EJ# : Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19. Science Immunology March 2021.

Herati RS, Silva LV, Vella LA, Muselman A, Kurupati RK, Kannan S, Bengsch B, Manne S, Ertl HCJ, Doyle SA, Schmader KE, Wherry EJ: Age is associated with altered TNF-NFkB signaling in Tfh responses to influenza vaccination. Cell Reports Medicine February 2021.

Buggert M, Vella LA, Nguyen S, Wu v, Chen Z, Japp A, Maldini C, Kuri-Cervantes L, Manne S, Bukh Brody I, Perez-Potti A, Giles JR, Antel J, Bar-Or A, Johnson ME, Picker L, Okoye A, Canaday DH, Naji A, Laufer TM, Wells AD, Björkström N, Frank I, Dori Y, Douek D, Wherry EJ, Itkin MG, Betts MR. : The identity of human tissue-emigrant CD8+ T cells. Cell December 2020.

Anderson EM, Diorio C, Goodwin EC, McNerney KO, Weirick ME, Gouma S, Bolton MJ , Arevalo CP, Chase J, Hicks P, Manzoni TB , Baxter AE , Andrea KP, Burudpakdee C , Lee JH, Vella LA , Henrickson SE , Harris RM , Wherry EJ, Bates P , Bassiri H , Behrens EM, Teachey DT, Hensley SE: SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19. J Pediatric Infect Dis Soc December 2020.

Anderson EM, Goodwin EC, Verma A, Arevalo CP, Bolton MJ, Weirick ME, Gouma S, McAllister CM, Christensen SR, Weaver J, Hicks P, Manzoni TB, Oniyide O, Ramage H, Mathew D, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, D’Andrea K, Kuthuru O, Dougherty J, Pattekar A, Kim J, Han N, Apostolidis SA, Huang AC, Vella LA, The UPenn COVID Processing Unit, Wherry EJ, Meyer NJ, Cherry S, Bates P, Rader DJ, Hensley SE: Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection. medRxiv: https://doi.org/10.1101/2020.11.06.20227215 November 2020.

Sharova A, Galetaki D, Hayes M, Gianchetti L, Vella LA , Downes KD: CMV Infection and Management Among Pediatric Solid Organ Transplant Recipients. Infectious Diseases Society of America IDWeek, Washington, DC, Poster October 2020.

Diorio C,* Anderson EA,* McNerney KO, Goodwin EC, Chase JC, Bolton MJ, Arevalo CP, Weirick ME, Gouma S, Vella L, Henrickson SE, Chiotos K, Fitzgerald JC, Killbaugh TJ, John ARO, Blatz AM, Lambert MP, Sullivan KE, Tartaglione MR, Zambrano D, Martin M, Lee JF, Young P, Friedman D, Sesok-Pizzini DA, Hensley SE, Behrens EM,* Bassiri H,* Teachey DT.*: Convalescent plasma for pediatric patients with SARS‐CoV‐2‐associated acute respiratory distress syndrome. Pediatric blood & cancer 67(11), September 2020.

Diorio C, Henrickson SE, Vella LA, McNerney K, Chase J, Burudpakdee C, Lee JH, Jasen C, Balamuth F, Barrett DM, Banwell BL, Bernt KM, Blatz A, Chiotos K, Fisher BT, Gerber JS, Gollomp K, Gray C, Grupp SA, Harris RM, Kilbaugh T, Odom John AR, Lambert M, Liebling EJ, Paessler M, Petrosa W, Phillips C, Romberg ND, Seif A, Sesok-Pizzini DA, Sullivan KE, Vardaro J, Behrens EM*, Teachey DT*, Bassiri H* : Distinct Cytokine Profiles and Microangiopathic Features Distinguish SARS-CoV2 Associated Multisystem Inflammatory Syndrome in Children (MIS-C) from COVID-19. Journal of Clinical Investigation July 2020.

Mathew D*, Giles JR*, Baxter AE*, Greenplate AR*, Wu JE*, Alanio C*, Oldridge DA*, Kuri-Cervantes L, Pampena MB, D’Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Hensley SE, Apostolidis S, Huang AC, Vella LA, The UPenn COVID Processing Unit, Betts MR*, Meyer NJ*, Wherry EJ*: Deep immune profiling of COVID-19 reveals distinct immunotypes with implications for therapeutic interventions. Science July 2020.

Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum R, Mathew D, Baxter AE, Vella LA, Kuthuru O, Apostolidis S, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ*, Meyer NJ*, Betts MR*: Comprehensive mapping of immune perturbations associated with severe COVID-19. Science Immunology July 2020.

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Last updated: 03/01/2021
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