Thomas H. Leung, M.D., Ph.D.

faculty photo
Assistant Professor of Dermatology
Co-director, Research Residency Track, University of Pennsylvania School of Medicine
Director, Duhring Lectureship Series, University of Pennsylvania School of Medicine
Department: Dermatology
Graduate Group Affiliations

Contact information
421 Curie Boulevard
1001 Biomedical Research Building II/III, Room 1006
Philadelphia, PA 19104
Education:
B.S. (Biological Sciences)
Stanford University, Stanford, CA, 1998.
Ph.D. (Biology)
California Institute of Technology, Pasadena, CA, 2005.
M.D. (Medicine)
UCLA School of Medicine, Los Angeles, CA, 2007.
Permanent link
 
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Sati S., Jones P., Kim H.S., Zhou L.A., Rapp-Reyes E., and Leung T.H. : HiCuT: An efficient and low input method to identify protein-directed chromatin interactions. PLoS Genet. 18(3): e1010121, Mar 23 2022 Notes: doi: 10.1371/journal.pgen.1010121. Online ahead of print.

Leung T.H. and Cotsarelis G.: Cellular Memories – More Than Skin Deep N Eng J Med 386(8): 793-795, Feb 2022 Notes: In press.

Peraramelli S., Zhou Q., Zhou Q., Wanko B., Zhao L., Nishimura T., Leung T.H., Mizuno S., Ito M., Myles T., Stulnig T.M., Morser J., and Leung L.L. : Thrombin cleavage of osteopontin initiates osteopontin’s tumor-promoting activity. J Thomb Haemost Feb 2 2022 Notes: doi: 10.1111/jth.15663. Online ahead of print.

Brennan-Crispi D.M., Frankfurter M., Murphy C., Sheng E., Xu M., Morrisey E.E., Millar S.E.*, and Leung T.H.* : FZD2 Regulates Murine Hair Follicle Function and Maintenance. J Invest Dermatol. S0022-202X(22): 00011-2, Jan 17 2022 Notes: *These authors contributed equally to this work. Online ahead of print.

Wei J.J., Kim H.S., Spencer C.A., Brennan-Crispi D., Zheng Y., Johnson N.M., Rosenbach M., Miller C., Leung, D.H., Cotsarelis G., and Leung T.H. : Activation of TRPA1 Nociceptor Promotes Systemic Adult Mammalian Skin Regeneration. Science Immunology 5(50), 2020.

Nishiguchi M.A., Spencer C.A., Leung D.H., and Leung T.H. : Aging suppresses skin-derived circulating SDF1 to promote full-thickness tissue regeneration. Cell Reports 24(13): 3383-3392, Oct 2018.

Siprashvili Z, Nguyen NT, Gorell ES, Loutit K, Khuu P, Furukawa LK, Lorenz HP, Leung TH, Keene DR, Rieger KE, Khavari P, Lane AT, Tang JY, Marinkovich MP: Safety and Wound Outcomes Following Genetically Corrected Autologous Epidermal Grafts in Patients With Recessive Dystrophic Epidermolysis Bullosa. JAMA 316(17): 1808, 2016.

Leung TH, Snyder ER, Liu Y, Wang J, Kim SK: A cellular, molecular, and pharmacological basis for appendage regeneration in mice. Genes Dev 29(20): 2097-107, 2015.

Gorrell, E.S., Leung, T.H., Khuu, P., Lane, A.T.: Purified Type I collagen wound matrix improves chronic wound healing in patients with recessive dystrophic epidermolysis bullosa. Pediatr Dermatol 32(2): 220-5, 2014.

Danial, C., Tichy, A.L., Tariq, U., Swetman, G.L., Khuu, P., Leung, T.H., Benjamin, L., Teng, J, Vasanawala, S.S., Lane, A.T.: An open-label study to evaluate sildenafil for the treatment of lymphatic malformations. J Am Acad Dermatol S0190-9622(14)01119-0, 2014.

back to top
Last updated: 03/24/2022
The Trustees of the University of Pennsylvania