Anthony Vincent Spadaro, MD, MPH

faculty photo
Assistant Professor of Emergency Medicine at the Hospital of the University of Pennsylvania
Attending Physician, Department of Emergency Medicine
Department: Emergency Medicine

Contact information
Department of Emergency Medicine
Administrative Office:
3400 Spruce Street
Ground Ravdin
Philadelphia, PA 19104
Office: 215-662-6698 - Ext 3
Education
BS (Biology)
Carnegie Mellon University, 2013.
MPH (Public Health)
Perelman School of Medicine at the University of Pennsylvania, 2019.
MD (Medicine)
Perelman School of Medicine at the University of Pennsylvania, 2019.
Post-Graduate Training
Resident, Emergency Medicine, Hospital of the University of Pennsylvania, 2019-2023.
Fellow, Medical toxicology and Addiction Medicine, Rutgers New Jersey Medical School and New Jersey Poison Information and Education System, 2023-2025.
Certifications
American Board of Emergency Medicine, 2023.
American Board of Preventative Medicine - Addiction Medicine, 2026.
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Description of Research Expertise

Opioid Use Disorder, Opioid Overdose, MOUD, Medical Toxicology

Selected Publications

Lakamana S, Das S, Spadaro A, Wightman R, Perrone J, Sarker A.: Monitoring novel psychoactive substance trends on social media: Analysis of discussions and dashboard implementation. Drug Alcohol Depend Jun 2026.

Sompalle P, Sarker A, Love J, Moon J, Spadaro A, Wightman R, Torgersen J, Perrone J.: Development and Validation of an Image-Based Deep Learning Tool for Identification of Xylazine-Associated Wounds. J Addict Med May 2026.

Spadaro A.: Combined Medical Toxicology and Addiction Medicine Training: A Fellow's Perspective. J Med Toxicol Apr 2026.

Spadaro A, Kelly T, Morris J, Heeney ME: Emergency Departments Need to Train and Hire More Sub-Specialists in Addiction Medicine. AEM Educ Train 2026.

Spadaro A, Hairston J, Lakamana S, Wightman R, Love JL, Perrone J, Sarker A. : Characterization of Reddit Posts About Xylazine-Associated Wounds: Qualitative Study. JMIR Dermatol 8: e70329, Sep 2025 Notes: 2025 Sep 12. doi:10.2196/70329.

Spadaro A, Calello DP, Counts CJ, Cerbini TA, Nelson LS, Greller HA: Rapid transition from a continuous naloxone infusion to sublingual buprenorphine after an opioid overdose: a case series. Subst Use Addctn J Aug 2025 Notes: doi: 10.1177/29767342251356351. Online ahead of print.

Thakrar A, Zwiebel S, Christine P, Spadaro A, Davis M, Bhatia R, Rohacs N, Xu L, Perrone J, Lowenstein M: Manifestations of a Potential Xylazine Withdrawal Syndrome Among Hospitalized Patients: A Retrospective Cohort Study with Nested Case Control. Drug Alcohol Depend Jul 2025 Notes: doi: 10.1016/j.drugalcdep.2025.112681. Epub 2025 Apr 30.

Spadaro A, Nath J, Mok T, Chen C, Nelson LS, Santos C: Parenteral Buprenorphine for Opioid Withdrawal J Stud Alcohol Drugs 86(3), May 2025.

Spadaro A, Perrone J, Nelson L, Greller HA: Reining It In: Xylazine Overdose. Critical Decisions in Emergency Medicine 39(5), May 2025.

Counts CJ, Spadaro A, Cerbini T, Krotulski AJ, Greller HA, Nelson LS, Ruck B, Calello DP: An Outbreak of Synthetic Cannabinoid-Adulterated Tianeptine Products in New Jersey – A Case Series. J Med Toxicol 21(2): 253-259, Apr 2025 Notes: doi: 10.1007/s13181-025-01068-7. Epub 2025 Mar 18.

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Last updated: 07/08/2026
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