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Anthony Vincent Spadaro, MD, MPH
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Assistant Professor of Emergency Medicine at the Hospital of the University of Pennsylvania
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Attending Physician, Department of Emergency Medicine
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Department: Emergency Medicine
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Contact information
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Department of Emergency Medicine
21 Administrative Office:
1a 3400 Spruce Street
30 Ground Ravdin
Philadelphia, PA 19104
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21 Administrative Office:
1a 3400 Spruce Street
30 Ground Ravdin
Philadelphia, PA 19104
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Office: 215-662-6698 - Ext 3
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Publications
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Links
b9 Search PubMed for articles
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b9 Search PubMed for articles
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Education:
21 7 BS 14 (Biology) c
33 Carnegie Mellon University, 2013.
21 8 MPH 1a (Public Health) c
56 Perelman School of Medicine at the University of Pennsylvania, 2019.
21 7 MD 15 (Medicine) c
56 Perelman School of Medicine at the University of Pennsylvania, 2019.
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21 7 BS 14 (Biology) c
33 Carnegie Mellon University, 2013.
21 8 MPH 1a (Public Health) c
56 Perelman School of Medicine at the University of Pennsylvania, 2019.
21 7 MD 15 (Medicine) c
56 Perelman School of Medicine at the University of Pennsylvania, 2019.
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Post-Graduate Training
24 66 Resident, Emergency Medicine, Hospital of the University of Pennsylvania, 2019-2023.
24 7f Associate Fellow, Public Health, Center for Public Health Initiatives, University of Pennsylvania, 2021-2023.
24 a9 Fellow, Medical toxicology and Addiction Medicine, Rutgers New Jersey Medical School and New Jersey Poison Information and Education System, 2023-2025.
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24 66 Resident, Emergency Medicine, Hospital of the University of Pennsylvania, 2019-2023.
24 7f Associate Fellow, Public Health, Center for Public Health Initiatives, University of Pennsylvania, 2021-2023.
24 a9 Fellow, Medical toxicology and Addiction Medicine, Rutgers New Jersey Medical School and New Jersey Poison Information and Education System, 2023-2025.
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Certifications
28 1d ATLS, 2019.
28 1d ACLS, 2019.
28 1d PALS, 2021.
28 3d American Board of Emergency Medicine, 2023.
28 54 Wound Care Educators, Physician Wound Care Education Course, 2024.
28 55 American Board of Preventative Medicine - Addiction Medicine, 2026.
28 48 Research in Addiction Medicine Scholars Program, 2026.
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Permanent link28 1d ATLS, 2019.
28 1d ACLS, 2019.
28 1d PALS, 2021.
28 3d American Board of Emergency Medicine, 2023.
28 54 Wound Care Educators, Physician Wound Care Education Course, 2024.
28 55 American Board of Preventative Medicine - Addiction Medicine, 2026.
28 48 Research in Addiction Medicine Scholars Program, 2026.
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161 Spadaro A, Calello DP, Counts CJ, Cerbini TA, Nelson LS, Greller HA: Rapid transition from a continuous naloxone infusion to sublingual buprenorphine after an opioid overdose: a case series. Subst Use Addctn J Aug 2025 Notes: doi: 10.1177/29767342251356351. Online ahead of print.
19e Thakrar A, Zwiebel S, Christine P, Spadaro A, Davis M, Bhatia R, Rohacs N, Xu L, Perrone J, Lowenstein M: Manifestations of a Potential Xylazine Withdrawal Syndrome Among Hospitalized Patients: A Retrospective Cohort Study with Nested Case Control. Drug Alcohol Depend Jul 2025 Notes: doi: 10.1016/j.drugalcdep.2025.112681. Epub 2025 Apr 30.
d5 Spadaro A, Nath J, Mok T, Chen C, Nelson LS, Santos C: Parenteral Buprenorphine for Opioid Withdrawal J Stud Alcohol Drugs 86(3), May 2025.
d0 Spadaro A, Perrone J, Nelson L, Greller HA: Reining It In: Xylazine Overdose. Critical Decisions in Emergency Medicine 39(5), May 2025.
169 Counts CJ, Spadaro A, Cerbini T, Krotulski AJ, Greller HA, Nelson LS, Ruck B, Calello DP: An Outbreak of Synthetic Cannabinoid-Adulterated Tianeptine Products in New Jersey – A Case Series. J Med Toxicol 21(2): 253-259, Apr 2025 Notes: doi: 10.1007/s13181-025-01068-7. Epub 2025 Mar 18.
1d2 Das S, Ge Y, Guo Y, Rajwal S, Hairston J, Powell J, Walker D, Peddireddy S, Lakamana S, Bozkurt S, Reyna M, Sameni R, Xiao Y, Kim S, Chandler R, Hernandez N, Mowery D, Wightman R, Love J, Spadaro A, Perrone J, Sarker A: Two-Layer Retrieval-Augmented Generation Framework for Low-Resource Medical Question Answering Using Reddit Data: Proof-of-Concept Study. J Med Internet Res 6(27), Jan 2025.
11e Spadaro A, Imperato N, Scalgione J, Santos C.: Intravenous Buprenorphine Reversed Opioid-Induced Respiratory Depression Without Precipitating Withdrawal in Emergency Department Patients. J Stud Alcohol Drugs 2025.
130 Hairston J, Ranjan R, Lakamana S, Spadaro A, Bozkurt S, Perrone J, Sarker A.: Automating inductive thematic analyses of health content using large language models: a proof-of-concept study using social media data. JAMIA Open 2025.
13b Javed, J, Spadaro A, Cinnevert E, Simmons B, Gordon E: GLP-1 Agonists in patients with cardiovascular disease and comorbid substance use disorder: a retrospective observational cohort study. American Heart Association Annual Meeting Nov 2024.
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Selected Publications
136 Spadaro A, Hairston J, Lakamana S, Wightman R, Love JL, Perrone J, Sarker A. : Characterization of Reddit Posts About Xylazine-Associated Wounds: Qualitative Study. JMIR Dermatol 8: e70329, Sep 2025 Notes: 2025 Sep 12. doi:10.2196/70329.161 Spadaro A, Calello DP, Counts CJ, Cerbini TA, Nelson LS, Greller HA: Rapid transition from a continuous naloxone infusion to sublingual buprenorphine after an opioid overdose: a case series. Subst Use Addctn J Aug 2025 Notes: doi: 10.1177/29767342251356351. Online ahead of print.
19e Thakrar A, Zwiebel S, Christine P, Spadaro A, Davis M, Bhatia R, Rohacs N, Xu L, Perrone J, Lowenstein M: Manifestations of a Potential Xylazine Withdrawal Syndrome Among Hospitalized Patients: A Retrospective Cohort Study with Nested Case Control. Drug Alcohol Depend Jul 2025 Notes: doi: 10.1016/j.drugalcdep.2025.112681. Epub 2025 Apr 30.
d5 Spadaro A, Nath J, Mok T, Chen C, Nelson LS, Santos C: Parenteral Buprenorphine for Opioid Withdrawal J Stud Alcohol Drugs 86(3), May 2025.
d0 Spadaro A, Perrone J, Nelson L, Greller HA: Reining It In: Xylazine Overdose. Critical Decisions in Emergency Medicine 39(5), May 2025.
169 Counts CJ, Spadaro A, Cerbini T, Krotulski AJ, Greller HA, Nelson LS, Ruck B, Calello DP: An Outbreak of Synthetic Cannabinoid-Adulterated Tianeptine Products in New Jersey – A Case Series. J Med Toxicol 21(2): 253-259, Apr 2025 Notes: doi: 10.1007/s13181-025-01068-7. Epub 2025 Mar 18.
1d2 Das S, Ge Y, Guo Y, Rajwal S, Hairston J, Powell J, Walker D, Peddireddy S, Lakamana S, Bozkurt S, Reyna M, Sameni R, Xiao Y, Kim S, Chandler R, Hernandez N, Mowery D, Wightman R, Love J, Spadaro A, Perrone J, Sarker A: Two-Layer Retrieval-Augmented Generation Framework for Low-Resource Medical Question Answering Using Reddit Data: Proof-of-Concept Study. J Med Internet Res 6(27), Jan 2025.
11e Spadaro A, Imperato N, Scalgione J, Santos C.: Intravenous Buprenorphine Reversed Opioid-Induced Respiratory Depression Without Precipitating Withdrawal in Emergency Department Patients. J Stud Alcohol Drugs 2025.
130 Hairston J, Ranjan R, Lakamana S, Spadaro A, Bozkurt S, Perrone J, Sarker A.: Automating inductive thematic analyses of health content using large language models: a proof-of-concept study using social media data. JAMIA Open 2025.
13b Javed, J, Spadaro A, Cinnevert E, Simmons B, Gordon E: GLP-1 Agonists in patients with cardiovascular disease and comorbid substance use disorder: a retrospective observational cohort study. American Heart Association Annual Meeting Nov 2024.
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