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Shih-Shan Lang Chen, MD
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Associate Professor of Neurosurgery at the Children's Hospital of Philadelphia
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Attending Neurosurgeon, Children's Hospital of Philadelphia (CHOP), University of Pennsylvania
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Attending Neurosurgeon, The Hospital of the University of Pennsylvania
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Attending Neurosurgeon, Penn Presbyterian Medical Center
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Department: Neurosurgery
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Contact information
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3500 civic center blvd
16 10th floor HUB
2f Neurosurgery
Philadelphia, PA 19104
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16 10th floor HUB
2f Neurosurgery
Philadelphia, PA 19104
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Office: 215-590-2780
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Email:
chens4@email.chop.edu
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chens4@email.chop.edu
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Education:
21 9 B.S. 25 (Neurobiological Sciences) c
2e University of Florida, 2002.
21 9 M.D. 15 (Medicine) c
42 University of Florida College of Medicine, 2007.
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21 9 B.S. 25 (Neurobiological Sciences) c
2e University of Florida, 2002.
21 9 M.D. 15 (Medicine) c
42 University of Florida College of Medicine, 2007.
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Post-Graduate Training
24 67 Internship in General Surgery, Hospital of the University of Pennsylvania, 2007-2008.
24 6a Resident in Neurological Surgery, Hospital of the University of Pennsylvania, 2008-2014.
24 6d Chief Resident in Neurological Surgery , Hospital of University of Pennsylvania, 2013-2014.
24 97 Fellowship in Pediatric Neurosurgery, Children's Hospital of Philadelphia, The Hospital of the University of Pennsylvania, 2014-2015.
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24 67 Internship in General Surgery, Hospital of the University of Pennsylvania, 2007-2008.
24 6a Resident in Neurological Surgery, Hospital of the University of Pennsylvania, 2008-2014.
24 6d Chief Resident in Neurological Surgery , Hospital of University of Pennsylvania, 2013-2014.
24 97 Fellowship in Pediatric Neurosurgery, Children's Hospital of Philadelphia, The Hospital of the University of Pennsylvania, 2014-2015.
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Certifications
28 40 American Board of Neurological Surgeons, 2019.
28 4a American Board of Pediatric Neurological Surgeons, 2019.
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Permanent link28 40 American Board of Neurological Surgeons, 2019.
28 4a American Board of Pediatric Neurological Surgeons, 2019.
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3a Pediatric Spine Trauma and Traumatic Brain Injury
1f Pediatric Brain Tumors
2d Neonatal and Pediatric Hydrocephalus
1f Endoscopic Neurosurgery
20 Cerebral Palsy Spasticity
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Description of Clinical Expertise
6c Vascular Neurosurgery – revascularization surgery, Aneurysms, arteriovenous malformations3a Pediatric Spine Trauma and Traumatic Brain Injury
1f Pediatric Brain Tumors
2d Neonatal and Pediatric Hydrocephalus
1f Endoscopic Neurosurgery
20 Cerebral Palsy Spasticity
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140 Kamila M. Bond, Shih-Shan Chen, Adam J. Kundishora: Temporal Patterns of Healthcare Utilization Identify Distinct Pediatric Neurotrauma Risk Profiles. AANS/CNS Pediatric Section Meeting December 2025 Notes: Oral Presentation by Dr. Bond (pending)
13d Kamila M. Bond, MD, PhD, Shih-Shan Chen, MD, Adam J. Kundishora, MD: Temporal Patterns of Healthcare Utilization Identify Distinct Pediatric Neurotrauma Risk Profiles. AANS/CNS Pediatric Section Meeting December 2025 Notes: Pending acceptance
123 Claudia Hejazi-Garcia, BA, Ellie D. Gabriel, MS, Jamal Magoti, BS, Sanjana R. Salwi, MD, Addison Quinones, MD, Susanna D. Howard, MD, Jimmy W. Huh, MD, Shih-Shan Lang, MD: The Area Deprivation Index (ADI) and Traumatic Brain Injury Outcomes 2 5f Congress of Neurological Surgeons. Poster presentation October 2025.
15d Shih-Shan Lang, Allison Hu, Scott Bartlett: Isolated Squamosal Synostosis: A Rare Craniosynostosis Subtype Revisited Through Cohort Analysis and Systematic Review. International Society of Craniofacial Surgeons (ISCFS) October 2025 Notes: Oral presentation by Shih-Shan Lang.
1ca Yousef Hattar, Julie Sesen, Tyra Martinez, Karthik Ashok, Adrian Lupieri, Shih-Shan Lang, Gregory G. Heuer, Alexander Tucker, Edward R. Smith, Aram Ghalal: Cell Division Cycle 42 Binding Protein Beta as a Plasma-Based Biomarker for Cerebral Cavernous Malformations. International Society of Pediatric Neurosurgeons (ISPN) October 2025 Notes: France, oral presentation by Yousef Hattar.
197 Allison Rodman, Allison Britt, Elizabeth Brooks, Shyla Pelletier, Phillip Storm, Yong Collins, Shay Overstone, Rebecca Ichord, Allison Hyland, Laura Caligiuri, Natalie Ullman, Laura DiDomenico, Lauren Beslow, Shih-Shan Lang, Adam Kundishora: Neurovascular Patient Tracker: Improving Long-Term Outcomes by Ensuring Appropriate Follow-Up for At-Risk Patients 2 2 a3 International Society of Pediatric Neurosurgeons (ISPN) October 2025 Notes: France, nursing symposium oral presentation by Allison Rodman.
124 Emma Mazzio, Craig Press, Alicia Alcamo, Shih-Shan Lang, Jimmy Huh, Raymond Liu, Alexis Topjian, Matthew Kirschen. : Association Between EEG Responsiveness to Hypertonic Saline Administration and Outcomes After Pediatric Acute Brain Injury. be Neurocritical Care Society Conference September 2025 Notes: Pending Submitted to Neurocritical Care Society Conference in March 2025 (for Montreal, September 2025).
124 Emma Mazzio, Craig Press, Alicia Alcamo, Shih-Shan Lang, Jimmy Huh, Raymond Liu, Alexis Topjian, Matthew Kirschen. : Association Between EEG Responsiveness to Hypertonic Saline Administration and Outcomes After Pediatric Acute Brain Injury. 3a Pediatric Neurocritical Care Research Group (PNCRG) 57 September 2025 Notes: Montreal, oral presentation by Emma Mazzio.
183 Yousef Hattar , Julie Sesen , Tyra Martinez , Adrian Lupieri , Shih-Shan Lang , Gregory H. Heuer , Alexander Tucker , Edward R. Smith and Aram Ghalali.: YES1, a Potential Plasma-Based Biomarker for Diagnosing Cerebral Cavernous Malformations. Frontiers August 2025 Notes: Under Revisions August 2025.
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Selected Publications
8b Kumaran Senthil, Vanessa Mazandi, Karla Resendiz, Shih-shan Lang, Ellie Gabriel, Todd Kilbaugh, ea Jimmy Huh: Safety of short term continuous propofol infusion for severe pediatric traumatic brain injury. Society of Critical Care Congress March 2026 Notes: Oral Presentation by Kumar Senthil (pending).140 Kamila M. Bond, Shih-Shan Chen, Adam J. Kundishora: Temporal Patterns of Healthcare Utilization Identify Distinct Pediatric Neurotrauma Risk Profiles. AANS/CNS Pediatric Section Meeting December 2025 Notes: Oral Presentation by Dr. Bond (pending)
13d Kamila M. Bond, MD, PhD, Shih-Shan Chen, MD, Adam J. Kundishora, MD: Temporal Patterns of Healthcare Utilization Identify Distinct Pediatric Neurotrauma Risk Profiles. AANS/CNS Pediatric Section Meeting December 2025 Notes: Pending acceptance
123 Claudia Hejazi-Garcia, BA, Ellie D. Gabriel, MS, Jamal Magoti, BS, Sanjana R. Salwi, MD, Addison Quinones, MD, Susanna D. Howard, MD, Jimmy W. Huh, MD, Shih-Shan Lang, MD: The Area Deprivation Index (ADI) and Traumatic Brain Injury Outcomes 2 5f Congress of Neurological Surgeons. Poster presentation October 2025.
15d Shih-Shan Lang, Allison Hu, Scott Bartlett: Isolated Squamosal Synostosis: A Rare Craniosynostosis Subtype Revisited Through Cohort Analysis and Systematic Review. International Society of Craniofacial Surgeons (ISCFS) October 2025 Notes: Oral presentation by Shih-Shan Lang.
1ca Yousef Hattar, Julie Sesen, Tyra Martinez, Karthik Ashok, Adrian Lupieri, Shih-Shan Lang, Gregory G. Heuer, Alexander Tucker, Edward R. Smith, Aram Ghalal: Cell Division Cycle 42 Binding Protein Beta as a Plasma-Based Biomarker for Cerebral Cavernous Malformations. International Society of Pediatric Neurosurgeons (ISPN) October 2025 Notes: France, oral presentation by Yousef Hattar.
197 Allison Rodman, Allison Britt, Elizabeth Brooks, Shyla Pelletier, Phillip Storm, Yong Collins, Shay Overstone, Rebecca Ichord, Allison Hyland, Laura Caligiuri, Natalie Ullman, Laura DiDomenico, Lauren Beslow, Shih-Shan Lang, Adam Kundishora: Neurovascular Patient Tracker: Improving Long-Term Outcomes by Ensuring Appropriate Follow-Up for At-Risk Patients 2 2 a3 International Society of Pediatric Neurosurgeons (ISPN) October 2025 Notes: France, nursing symposium oral presentation by Allison Rodman.
124 Emma Mazzio, Craig Press, Alicia Alcamo, Shih-Shan Lang, Jimmy Huh, Raymond Liu, Alexis Topjian, Matthew Kirschen. : Association Between EEG Responsiveness to Hypertonic Saline Administration and Outcomes After Pediatric Acute Brain Injury. be Neurocritical Care Society Conference September 2025 Notes: Pending Submitted to Neurocritical Care Society Conference in March 2025 (for Montreal, September 2025).
124 Emma Mazzio, Craig Press, Alicia Alcamo, Shih-Shan Lang, Jimmy Huh, Raymond Liu, Alexis Topjian, Matthew Kirschen. : Association Between EEG Responsiveness to Hypertonic Saline Administration and Outcomes After Pediatric Acute Brain Injury. 3a Pediatric Neurocritical Care Research Group (PNCRG) 57 September 2025 Notes: Montreal, oral presentation by Emma Mazzio.
183 Yousef Hattar , Julie Sesen , Tyra Martinez , Adrian Lupieri , Shih-Shan Lang , Gregory H. Heuer , Alexander Tucker , Edward R. Smith and Aram Ghalali.: YES1, a Potential Plasma-Based Biomarker for Diagnosing Cerebral Cavernous Malformations. Frontiers August 2025 Notes: Under Revisions August 2025.
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