Peter J. Madsen, MD
Assistant Professor of Neurosurgery at the Children's Hospital of Philadelphia
Director of Neurosurgical Oncology and Translational Research, Division of Neurosurgery, Children's Hospital of Philadelphia
Department: Neurosurgery
Contact information
The Children’s Hospital of Philadelphia
Division of Neurosurgery
10th Floor, The Hub for Clinical Collaboration
3500 Civic Center Blvd.
Philadelphia, PA 19104
Division of Neurosurgery
10th Floor, The Hub for Clinical Collaboration
3500 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215.590.2780
Education:
BS (Chemistry (University Honors))
Carnegie Mellon University, 2008.
MD (Medicine)
Perelman School of Medicine, University of Pennsylvania, 2013.
MS (Bioethics)
Perelman School of Medicine, University of Pennsylvania, 2013.
BS (Chemistry (University Honors))
Carnegie Mellon University, 2008.
MD (Medicine)
Perelman School of Medicine, University of Pennsylvania, 2013.
MS (Bioethics)
Perelman School of Medicine, University of Pennsylvania, 2013.
Post-Graduate Training
Resident, Department of Neurosurgery, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2013-2019.
Fellow, Neurosurgical Oncology & Skull Base Surgery, Division of Neurosurgery, Wellington Regional Hospital, Wellington, New Zealand, 2018-2018.
Chief Resident, Department of Neurosurgery, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2019-2020.
Fellow, Pediatric Neurosurgery, Division of Neurosurgery, Children’s Hospital of Philadelphia, Philadelphia, PA, 2020-2021.
Resident, Department of Neurosurgery, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2013-2019.
Fellow, Neurosurgical Oncology & Skull Base Surgery, Division of Neurosurgery, Wellington Regional Hospital, Wellington, New Zealand, 2018-2018.
Chief Resident, Department of Neurosurgery, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2019-2020.
Fellow, Pediatric Neurosurgery, Division of Neurosurgery, Children’s Hospital of Philadelphia, Philadelphia, PA, 2020-2021.
Certifications
American Board of Neurologic Surgeons, 2025.
Permanent linkAmerican Board of Neurologic Surgeons, 2025.
Selected Publications
Pomaville M, Mouck M, Lavorando E, Hajeebu S, Vo D, Joshi N, Wang F, Park J, Sullenberger M, Zhu G, Beaubien E, McManus O, Madsen PJ, Fange Liu K, Xing Y, Foster J.: Manipulation of the RNA modification m6A to induce tumor-specific antigens in high-grade glioma. Neuro-Oncology Pediatrics 1(Issue Supp 1), Aug 2025.Bhatia A, Bloy L, Triolo E, Berman JI, Afolabi A, Kotha A, Kline C, LaRiviere M, Madsen PJ, Foster JB, Fisher MJ, Boada FE, Roberts TPL. : Technological Advancements of Sodium MRI in Pediatric Brain Tumors. Neuro-Oncology Pediatrics 1(Issue Suppl 1), Aug 2025.
Bhatia A, Kline C, Madsen PJ, Fisher MJ, Boada FE, Roberts TPL.: Sodium MRI in Pediatric Brain Tumors. AJNR Am J Neuroradiol 46(7): 1309-17, Jul 2025.
Foster JB, Madsen PJ, Harvey K, Griffin C, Stern A, Patterson L, Joshi N, Dickson C, McManus O, Beaubien E, Wilson C, Beale DR, Baubet V, Goel P PN, Vitanza NA, Nazarian J, Koptyra M, Storm PB, Resnick AC: Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high grade glioma models. Neuro Oncol May 2025.
Baumgartner ME, Galligan K, Flanders TM, Tucker AM, Madsen PJ, Kennedy BC.: Burr Hole Hemispherotomy: Case Series. Oper Neurosurg Mar 2025.
Naqvi AS, Corbett RJ, Seghal P, Conkrite KL, Rathi KS, Ennis BM, Hayer KE, Zhang B, Brown MA, Miller DP, Kraya AA, Coleman KL, Dybas JM, Geng Z, Blackden C, Arif S, Chroni A, Lahiri A, Hollawell ML, Storm PB, Haydar D, Foster JB, Koptyra M, Madsen PJ, Diskin SJ, Thomas-Tikhonenko A, Resnick AC, Rokita JL: Characterization of aberrant splicing in pediatric central nervous system tumors reveals CLK1 as a candidate oncogenic dependency. bioRxiv Feb 2025.
Xu E, Zhang E, Park K, Ayub M, Zhao C, Huh JW, King JM, Paltin I, Shah AC, Storm PB, Tucker A, Madsen PJ, Lang SS: Medical management of cerebellar mutism syndrome at a quaternary children's hospital. Childs Nerv Syst 41(1), Feb 2025.
Amiruddin R, States L, Madsen P, Aboian M: Role of PET/MR imaging in the management of pure erythroid sarcoma of the pediatric central nervous system. American Society of Neuroradiology (ASNR) Annual Meeting. Philadelphia, PA 2025.
Tapescu I, Madsen PJ, Lowenstein PR, Castro MG, Bagley SJ, Fan Y, Brem S: The transformative potential of mRNA vaccines for glioblastoma and human cancer: technological advances and translation to clinical trials. Front Oncol 14, Sep 2024.
Flanders TM, Kumar NK, Zhao C, Joerger TA, Huh JW, Buzi A, Rizzi MD, Settoon C, Storm PB, Heuer GG, Kennedy BC, Tucker AM, Madsen PJ, Lang SS: Intracranial complications secondary to acute bacterial sinusitis requiring neurosurgical intervention before and after the onset of the COVID-19 pandemic. J Neurosurg Pediatr 34(5): 479-88, Aug 2024.