Ryan Jamiolkowski, MD, PhD

faculty photo
Assistant Professor of Neurosurgery at the Hospital of the University of Pennsylvania
Department: Neurosurgery

Contact information
Pennsylvania Hospital
Department of Neurosurgery
801 Spruce Street, Floor 3
Philadelphia, PA 19104
Education
A.B. (Chemistry and Physics with a minor in Chinese; Graduated Magna Cum Laude)
Harvard University, 2009.
Ph.D. (Bioengineering in Laboratory of Prof. Yale E. Goldman)
University of Pennsylvania School of Engineering and Applied Sciences, 2016.
M.D. (Medicine; Member of Alpha Omega Honor Society)
University of Pennsylvania Perelman School of Medicine, 2018.
Post-Graduate Training
Resident, Department of Neurological Surgery, Stanford University, Palo Alto, CA, 2018-2025.
Research Fellow, Soltesz Lab, Stanford University, Department of Neurosurgery, 2021-2023.
Enfolded Functional/Epilepsy Fellow, Department of Neurosurgery, Stanford University, Palo Alto, CA, 2021-2023.
Postdoctoral Fellow, Stanford Maternal and Child Research Institute (MCHRI) Tashia and John Morgridge Endowed Postdoctoral Fellowship, 2022-2023.
Functional Fellow, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 2025-2026.
Permanent link
 
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Selected Publications

Willsey MS, Shah NP, Avansino DT, Hahn N, Jamiolkowski RM, Kamdar F, Hochberg LR, Willet F, Henderson JM : A high-performance brain–computer interface for finger decoding and quadcopter game control in an individual with paralysis Nat Med 31(1): 96-104, Jan 2025.

Jamiolkowski RM, Datta A, Willsey M, Parvizi J, Buch VP: Multinuclear thalamic targeting with human stereotactic electroencephalography: surgical technique and nuances. J Neurosurg 142(4): 936-944, Nov 2024.

Jamiolkowski RM*, Nguyen QA*, Farrell JS, McGinn RJ, Hartmann DA, Nirschl JJ, Sanchez MI, Buch VP, Soltesz I: The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy. Nat Med 30(5): 1292-1299, May 2024.

Guo LY, Bian J, Davis AE, Liu P, Kempton HR, Zhang X, Chemparathy A, Gu B, Lin X, Rane DA, Xu X, Jamiolkowski RM, Hu Y, Wang S, Qi LS: Multiplexed genome regulation in vivo with hyper-efficient Cas12a Nature Cell Biology 24(4): 590-600, Apr 2022.

Guo LY, Jamiolkowski RM, Hassan M, Leng T: A buoyant mass in the brain: Intraventricular migration of silicone oil. Am J Ophthalmology Case Rep 25: 101399, Feb 2022.

Parker JJ, Jamiolkowski RM, Grant GA, Le S, Halpern CH: Hybrid fluoroscopic and electrophysiologic guidance for Rolandic cortex cortical lead placement for epilepsy neuromodulation Operative Neurosurg 21(3): E180-E186, Jun 2021.

Chen K, Jamiolkowski RM, Fiorenza S, Tate A, Pfeil S, Goldman YE: Simple and inexpensive fabrication of zero mode waveguides for high concentration single molecule microscopy. J Vis Exp 12(159): e61154, May 2020.

Jamiolkowski RM, Chen K, Fiorenza S, Tate A, Pfeil S, Goldman YE: Nanoaperture fabrication via colloidal lithography for single molecule fluorescence analysis. PLOS One 14(10): e0222964, Oct 2019.

Ng MY, Zhang H, Weil A, Singh V, Jamiolkowski R, Baradaran-Heravi A, Roberge M, Jacobson A, Friesen W, Welch E, Goldman YE, Cooperman BS: New in Vitro Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery. ACS Med Chem Lett 9(12): 1285-1291, Nov 2018.

Caporizzo MA, Fishman CE, Sato O, Jamiolkowski RM, Ikebe M, Goldman YE: The antiparallel dimerization of myosin X imparts bundle selectivity for processive motility. Biophys J 114(6): 1400-1410, Mar 2018.

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Last updated: 04/02/2026
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