David J. Vaughn, M.D.
Emeritus Professor CE of Medicine (Hematology-Oncology)
Department: Medicine
Contact information
Education
A.B. (Spanish)
Dartmouth College, 1982.
M.D. (Medicine)
Harvard Medical School, 1987.
Permanent linkA.B. (Spanish)
Dartmouth College, 1982.
M.D. (Medicine)
Harvard Medical School, 1987.
Description of Research Expertise
New Drug Development for Urologic CancerCancer Survivorship
Description of Clinical Expertise
Urologic OncologyBladder Cancer
Prostate Cancer
Testis Cancer
Cancer Survivorship
Selected Publications
Kerns SL, Dinh Jr, Monahan PO , Fung C, Sesso HD, Feldman DR , Hamilton RJ , Vaughn DJ, Kollmannsberger C, Martin NE, Einhorn LH, Travis LB : Renal impairment and late toxicities comparing contemporary chemotherapy regimens for testicular cancer in a real-world setting Journal of the National Comprehensive Cancer Network 24(3): 81-90, Feb 2026.Nakshatri S, Dinh PC Jr, Einhorn LH, Feldman DR, Hamilton RJ, Vaughn DJ, Fung C, Kollmannsberger C, Huddart RA, Travis LB, Cox NJ, Dolan ME: Impact of population pharmacogenomics on cisplatin-Induced neurotoxicities in testicular cancer survivors. Cancer Medicine. 2025 Sep;14(17): doi: 10.1002/cam4.71218. 14(17): e71218. Sep 2025.
Kerns SL, Dinh PC Jr, Monahan PO, Stump T, Fung C, Sesso HD, Feldman DR, Hamilton RJ, Vaughn DJ, Huddart R, Kollmannsberger C, Martin NE, Nevel K, Kincaid J, Einhorn LH, Travis LB: Factors associated with longitudinal progression of the cumulative burden of morbidity and overall mortality after cisplatin-based chemotherapy for testicular cancer. Journal of the National Cancer Institute 1(117): 1797-1808, Sep 2025 Notes: Online ahead of print.
Cortese BD, Alkhatib KY, Harmatz IM, Michel KF, Lee DJ, Guzzo TJ, Vaughn DJ, Moses KA, Pierorazio PM, Talwar R.: The impact of telemedicine on racial and ethnic disparities in oncologic care during the COVID-19 pandemic. Am J Cancer Res 15: 1224-1233, Mar 2025.
Ugalde-Morales E, Wilf R, Pluta J, Ploner A, Fan M, Damra M, Aben KK, Anson-Cartwright L, Chen C, Cortessis VK, Daneshmand S, Ferlin A, Gamulin M, Gietema JA, Gonzalez-Niera A, Grotmol T, Hamilton RJ, Harland M, Haugen TB, Hauser R, Hildebrandt MAT, Karlsson R, Kiemeney LA, Kim J, Lessel D, Lothe RA, Loveday C, Chanock SJ, McGlynn KA, Meijer C, Nead KT, Nsengimana J, Popovic M, Rafnar T, Richiardi L, Rocca MS, Schwartz SM, Skotheim RI, Stefansson K, Stewart DR, Turnbull C, Vaughn DJ, Winge SB, Zheng T, Monteiro AN, Almstrup K, Kanetsky PA, Nathanson KL, Wiklund F; Testicular Cancer Consortium: Identification of genes associated with testicular germ cell tumor susceptibility through a transcriptome-wide association study. American Journal of Human Genetics 112(3): 630-643, Mar 2025.
Dinh PC Jr, Monahan PO, Fung C, Sesso HD, Feldman DR, Vaughn DJ, Hamilton RJ, Huddart R, Martin NE, Kollmannsberger C, Althouse S, Einhorn LH, Frisina R, Root JC, Ahles TA, Travis LB: Cognitive function in long-term testicular cancer survivors: impact of modifiable factors. Journal of the National Cancer Institute Cancer Spectrum Sep 2024 Notes: On line ahead of print.
de Wit R, Vaughn DJ, Fradet Y, Fong L, Climent MA, Necchi A, Petrylak DP, Gerritsen WR, Gurney H, Quinn DI, Culine S, Sternberg CN, Bajorin DF, Choueiri TK, Xu J, Imai K, Homet Moreno B, Bellmunt J, Lee JL.: Impact of prior chemotherapy on response to second-line pembrolizumab in urothelial cancer: exploratory analysis of the phase 3 KEYNOTE-045 trial. European Urology Aug 2024 Notes: Online ahead of print.
Welch E, Guerraty MA, Demissei BG, Haas N, Takvorian S, Parikh RB, Vaughn DJ, Pryma D, Mankoff DA, Ky B, Narayan V: Coronary microvascular dysfunction in men with prostate cancer receiving androgen-deprivation therapy. Clinical Genitourinary Cancer 22(4), Aug 2024 Notes: Epub ahead of print.
Hsu M, Shan X, Zhang R, Berlin E, Goel A, Agarwal M, Wong YN, Christodouleas JP, Vaughn DJ, Narayan V, Takvorian SU, Vapiwala N, Pantel AR, Haas NB: Prostate cancer recurrence: examining the role of salvage radiotherapy field and risk factors for regional disease recurrence captured on 18F-DCFPyL PET/CT. Clinical Genitourinary Cancer 22(4), Aug 2024 Notes: Epub ahead of print.
Demissei BG, Ko K, Huang A, Lee DJ, Doucette AG, Smith AM, Wilcox NS, Reibel J, Sun L, Agarwal M, Haas NB, Hollis G, Shpilsky JE, Takvorian SU, Vaughn DJ, Chen J, Hubbard RA, Powell-Wiley T, Yancy C, Narayan V, Ky B: Social determinants of health mediate racial disparities in cardiovascular disease in men With prostate cancer. Journal of the American College of Cardiology Cardio-Oncology 6: 390-401, Jun 2024.