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Ivan P. Maillard, MD, PhD

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Adjunct Professor of Medicine (Hematology-Oncology)
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Department: Medicine
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Memorial Sloan Kettering Cancer Center
2f 1275 York Avenue
New York, NY 10065
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2e Office: 215-746-2929
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Email: imaillar@pennmedicine.upenn.edu
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2f Gymnase de Chamblandes, 1986.
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3a University of Lausanne and Zurich, 1993.
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3a Swiss Academy of Medical Sciences, 1997.
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Description of Research Expertise

2da My laboratory investigates the regulation of normal and malignant hematopoiesis, bone marrow transplantation and T cell alloimmunity. A central focus of our studies is the role of Notch signaling in T cell development, differentiation and function. Using mouse models of bone marrow transplantation, we discovered essential functions for Notch receptors and ligands in graft-versus-host disease with a high fundamental and translational impact. We are also interested to understand the role of fibroblastic reticular cells as a source of Notch ligands and other signals in secondary lymphoid organs, with a focus on their emerging roles in immune regulation as well as in immunological and hematological disorders.
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Description of Clinical Expertise

2a Hematological malignancies
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34 The Trustees of the University of Pennsylvania c
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