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Lainie P. Martin, MD
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Associate Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
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Department: Medicine
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Contact information
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Perelman Center for Advanced Medicine
3d 10th Floor, South Pavilion
Philadelphia, PA 19104
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3d 10th Floor, South Pavilion
Philadelphia, PA 19104
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Education:
21 7 BA 16 (Economics) c
33 University of Pennsylvania, 1990.
21 c Post BA 25 (MCAT and Medical School ) c
2e Villanova University , 1995.
21 7 MD 1b (Medical School) c
3e Temple University School of Medicine , 1999.
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Permanent link21 7 BA 16 (Economics) c
33 University of Pennsylvania, 1990.
21 c Post BA 25 (MCAT and Medical School ) c
2e Villanova University , 1995.
21 7 MD 1b (Medical School) c
3e Temple University School of Medicine , 1999.
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30c You, B., Purdy, C., Copeland, L. J., Swisher, E. M., Bookman, M. A., Fleming, G., Coleman, R., Randall, L. M., Tewari, K. S., Monk, B. J., Mannel, R. S., Walker, J. L., Cappuccini, F., Cohn, D., Muzaffar, M., Mutch, D., Wahner-Hendrickson, A., Martin, L., Colomban, O., & Burger, R. A.: Identification of Patients With Ovarian Cancer Experiencing the Highest Benefit From Bevacizumab in the First-Line Setting on the Basis of Their Tumor-Intrinsic Chemosensitivity (KELIM): The GOG-0218 Validation Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2201207. Advance online publication. https://doi.org/10.1200/JCO.22.01207 40(34): 3965-3974, Dec 1 2022.
1c6 Shah PD, Wethington SL, Pagan C, Latif N, Tanyi J, Martin LP, Morgan M, Burger RA, Haggerty A, Zarrin H, Rodriguez D, Domchek S, Drapkin R, Shih IM, Smith SA, Dean E, Gaillard S, Armstrong D, Torigian DA, Hwang WT, Giuntoli R, Simpkins F.: Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-resistant epithelial ovarian cancer. 2 43 Gynecol Oncol. 163(2): 246-253, Nov 2021.
1c8 Hatch, R. V., Patel, S. U., Cambareri, C., Uritsky, T., & Martin, L. P.: Evaluation of the management of PARP inhibitor toxicities in ovarian and endometrial cancer within a multi-institution health-system. Journal of oncology pharmacy practice: official publication of the International Society of Oncology Pharmacy Practitioners Page: doi.org/10.1177/10781552211024728, June 2021.
c4 O'Malley DM, Matulonis UA, Birrer MJ, Castro CM, Gilbert L, Vergote I, Martin LP, Mantia-Smaldone GM, Martin AG, Bratos R, Penson RT, Malek K, Moore KN. d3 : Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRĪ±)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer. 42 Gynecol Oncol. 157(2): 379-385, May 2020.
231 Westin SN, Sill MW, Coleman RL, Waggoner S, Moore KN, Mathews CA, Martin LP, Modesitt SC, Lee S, Ju Z, Mills GB, Schilder RJ, Fracasso PM, Birrer MJ, Aghajanian C.: Safety lead-in of the MEK inhibitor trametinib in combination with GSK2141795, an AKT inhibitor, in patients with recurrent endometrial cancer: An NRG Oncology/GOG study. Gynecol Oncol. 2019 Oct 15. pii: S0090-8258(19). doi: 10.1016/j.ygyno.2019.09.024. [Epub ahead of print] epub ahead of print(19): 31548-3, October 2019.
ce Birrer MJ, Betella I, Martin LP, Moore KN: Is Targeting the Folate Receptor in Ovarian Cancer Coming of Age? Oncologist 24(4): 425-29, Apr 2019 Notes: 14
18b Matulonis UA, Birrer MJ, O'Malley DM, Moore KN, Konner J, Gilbert L, Martin LP, Bauer TM, Oza AM, Malek K, Pinkas J, Kim SK: Evaluation of Prophylactic Corticosteroid Eye Drop Use in the Management of Corneal Abnormalities Induced by the Antibody-Drug Conjugate Mirvetuximab Soravtansine. Clin Cancer Res 25(6): 1727-36, Mar 15 2019 Notes: 14
118 Patel D, Handorf E, von Mehren M, Martin L, Movva S.: Adjuvant Chemotherapy in Uterine Leiomyosarcoma: Trends and Factors Impacting Usage. Sarcoma 2019: 3561501, Feb 10 2019 Notes: doi: 10.1155/2019/3561501. eCollection 2019. 14
21e Falchook G, Coleman RL, Roszak A, Behbakht K, Matulonis U, Ray-Coquard I, Sawrycki P, Duska LR, Tew W, Ghamande S, Lesoin A, Schwartz PE, Buscema J, Fabbro M, Lortholary A, Goff B, Kurzrock R, Martin LP, Gray HJ, Fu S, Sheldon-Waniga E, Lin HM, Venkatakrishnan K, Zhou X, Leonard EJ, Schilder RJ: Alisertib in Combination With Weekly Paclitaxel in Patients With Advanced Breast Cancer or Recurrent Ovarian Cancer: A Randomized Clinical Trial. JAMA Oncol 5(1): e183773, Jan 1 2019 Notes: 2 2 2 14
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Selected Publications
221 Armstrong DK, Alvarez RD, Backes FJ, Bakkum-Gamez JN, Barroilhet L, Behbakht K, Berchuck A, Chen LM, Chitiyo VC, Cristea M, DeRosa M, Eisenhauer EL, Gershenson DM, Gray HJ, Grisham R, Hakam A, Jain A, Karam A, Konecny GE, Leath Iii CA, Leiserowitz G, Liu J, Martin L, Matei D, McHale M, McLean K, Miller DS, Percac-Lima S, Remmenga SW, Schorge J, Stewart D, Thaker PH, Vargas R, Hendrickson AW, Werner TL, Zsiros E, Dwyer MA, Hang L.: NCCN GuidelinesĀ® Insights: Ovarian Cancer, Version 3.2022. 2 1f J Natl Compr Canc Netw. 2e 20(9): 972-980, Sep 2022.30c You, B., Purdy, C., Copeland, L. J., Swisher, E. M., Bookman, M. A., Fleming, G., Coleman, R., Randall, L. M., Tewari, K. S., Monk, B. J., Mannel, R. S., Walker, J. L., Cappuccini, F., Cohn, D., Muzaffar, M., Mutch, D., Wahner-Hendrickson, A., Martin, L., Colomban, O., & Burger, R. A.: Identification of Patients With Ovarian Cancer Experiencing the Highest Benefit From Bevacizumab in the First-Line Setting on the Basis of Their Tumor-Intrinsic Chemosensitivity (KELIM): The GOG-0218 Validation Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2201207. Advance online publication. https://doi.org/10.1200/JCO.22.01207 40(34): 3965-3974, Dec 1 2022.
1c6 Shah PD, Wethington SL, Pagan C, Latif N, Tanyi J, Martin LP, Morgan M, Burger RA, Haggerty A, Zarrin H, Rodriguez D, Domchek S, Drapkin R, Shih IM, Smith SA, Dean E, Gaillard S, Armstrong D, Torigian DA, Hwang WT, Giuntoli R, Simpkins F.: Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-resistant epithelial ovarian cancer. 2 43 Gynecol Oncol. 163(2): 246-253, Nov 2021.
1c8 Hatch, R. V., Patel, S. U., Cambareri, C., Uritsky, T., & Martin, L. P.: Evaluation of the management of PARP inhibitor toxicities in ovarian and endometrial cancer within a multi-institution health-system. Journal of oncology pharmacy practice: official publication of the International Society of Oncology Pharmacy Practitioners Page: doi.org/10.1177/10781552211024728, June 2021.
c4 O'Malley DM, Matulonis UA, Birrer MJ, Castro CM, Gilbert L, Vergote I, Martin LP, Mantia-Smaldone GM, Martin AG, Bratos R, Penson RT, Malek K, Moore KN. d3 : Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRĪ±)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer. 42 Gynecol Oncol. 157(2): 379-385, May 2020.
231 Westin SN, Sill MW, Coleman RL, Waggoner S, Moore KN, Mathews CA, Martin LP, Modesitt SC, Lee S, Ju Z, Mills GB, Schilder RJ, Fracasso PM, Birrer MJ, Aghajanian C.: Safety lead-in of the MEK inhibitor trametinib in combination with GSK2141795, an AKT inhibitor, in patients with recurrent endometrial cancer: An NRG Oncology/GOG study. Gynecol Oncol. 2019 Oct 15. pii: S0090-8258(19). doi: 10.1016/j.ygyno.2019.09.024. [Epub ahead of print] epub ahead of print(19): 31548-3, October 2019.
ce Birrer MJ, Betella I, Martin LP, Moore KN: Is Targeting the Folate Receptor in Ovarian Cancer Coming of Age? Oncologist 24(4): 425-29, Apr 2019 Notes: 14
18b Matulonis UA, Birrer MJ, O'Malley DM, Moore KN, Konner J, Gilbert L, Martin LP, Bauer TM, Oza AM, Malek K, Pinkas J, Kim SK: Evaluation of Prophylactic Corticosteroid Eye Drop Use in the Management of Corneal Abnormalities Induced by the Antibody-Drug Conjugate Mirvetuximab Soravtansine. Clin Cancer Res 25(6): 1727-36, Mar 15 2019 Notes: 14
118 Patel D, Handorf E, von Mehren M, Martin L, Movva S.: Adjuvant Chemotherapy in Uterine Leiomyosarcoma: Trends and Factors Impacting Usage. Sarcoma 2019: 3561501, Feb 10 2019 Notes: doi: 10.1155/2019/3561501. eCollection 2019. 14
21e Falchook G, Coleman RL, Roszak A, Behbakht K, Matulonis U, Ray-Coquard I, Sawrycki P, Duska LR, Tew W, Ghamande S, Lesoin A, Schwartz PE, Buscema J, Fabbro M, Lortholary A, Goff B, Kurzrock R, Martin LP, Gray HJ, Fu S, Sheldon-Waniga E, Lin HM, Venkatakrishnan K, Zhou X, Leonard EJ, Schilder RJ: Alisertib in Combination With Weekly Paclitaxel in Patients With Advanced Breast Cancer or Recurrent Ovarian Cancer: A Randomized Clinical Trial. JAMA Oncol 5(1): e183773, Jan 1 2019 Notes: 2 2 2 14
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