Nune Markosyan, PhD
Adjunct Assistant Professor of Medicine (Hematology-Oncology)
Department: Medicine
Contact information
Abramson Cancer Center
Smilow Center for Translational Research
8th Floor, Room 8-179
3400 Civic Center Blvd
Philadelphia, PA 19104
Smilow Center for Translational Research
8th Floor, Room 8-179
3400 Civic Center Blvd
Philadelphia, PA 19104
Education:
MD (7 year MD degree program including undergraduate education)
Yerevan State Medical Institute , 1983.
PhD
Eastern Virginia Medical School , 2008.
Permanent linkMD (7 year MD degree program including undergraduate education)
Yerevan State Medical Institute , 1983.
PhD
Eastern Virginia Medical School , 2008.
Selected Publications
Markosyan N, Chen EP, Smyth EM.: Targeting COX-2 abrogates mammary tumorigenesis: Breaking cancer-associated suppression of immunosurveillance. Oncoimmunology 3: e29287, Jun 30 204.Rech A, Smyth EM, FitzGerald GA, Vonderheide RH. : mPGES1 Deletion and Mechanisms of Tumor Growth Suppression Third CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference, New York, NY Sep 2016 Notes: "Poster Presentation"
Evans RA, Diamond MS, Rech AJ, Chao T, Richardson MW, Lin JH, Bajor DL, Byrne KT, Stanger BZ, Riley JL, Markosyan N, Winograd R, Vonderheide RH.: Lack of immunoediting in murine pancreatic cancer reversed with neoantigen. JCI Insight 1(14), Sep 8 2016.
Kim SO, Markosyan N, Pepe GJ, Duffy DM.: Estrogen promotes luteolysis by redistributing prostaglandin F2α receptors within primate luteal cells. Reproduction 149(5): 453-64, May 2015.
Chen EP, Markosyan N, Connolly E, Lawson JA, Li X, Grant GR, Grosser T, FitzGerald GA, Smyth EM.: Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function. Carcinogenesis 35(8): 1788-97, Aug 2014.
Markosyan N, FitzGerald GA, Smyth E.: Deletion of Mammary Epithelial mPGES1 Suppresses Tumor Development in Mice: a Possible Effect of Substrate Re-diversion American Association for Cancer Research Annual Meeting,San Diego, CA Apr 2014 Notes: "Oral Presentation"
Markosyan N, FitzGerald GA, Smyth E.: Epithelial mPGES1 Deletion and Mammary Tumorigenesis 15th International Winter Eicosanoid Conference, Baltimore, MD Mar 2014 Notes: "Oral Presentation"
Ibrahim S, McCartney A, Markosyan N, Smyth EM.: Heterodimerization with the prostacyclin receptor triggers thromboxane receptor relocation to lipid rafts. Arterioscler Thromb Vasc Biol 33(1): 60-6, Jan 2013.
Markosyan N, Chen EP, Evans RA, Ndong V, Vonderheide RH, Smyth EM.: Mammary carcinoma cell derived cyclooxygenase 2 suppresses tumor immune surveillance by enhancing intratumoral immune checkpoint activity. Breast Cancer Res 15(5): R75, 2013.
Markosyan N, Chen EP, Ndong VN, Yao Y, Sterner CJ, Chodosh LA, Lawson JA, Fitzgerald GA, Smyth EM.: Deletion of cyclooxygenase 2 in mouse mammary epithelial cells delays breast cancer onset through augmentation of type 1 immune responses in tumors. Carcinogenesis 32(10): 1441-9, Oct 2011.