Therese Bittermann, MD, MSCE

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
Penn Transplant Institute
2 Dulles
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-349-8222
Fax: 215-349-5915
BA (Biological Sciences; International Studies)
Northwestern University, 2005.
MS (Physiology and Biophysics)
Georgetown University, 2006.
MD (Medicine)
Drexel University College of Medicine, 2010.
MS (Clinical Epidemiology)
University of Pennsylvania, 2017.
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Description of Clinical Expertise

I care for patients with viral hepatitis, auto-immune diseases of the liver, fatty liver disease, liver tumors, and cirrhosis. I also have expertise in pre- and post-transplantation management.

Description of Research Expertise

I study the relationship between immunosuppression strategy and outcomes after liver transplantation. I have previous expertise in research related to organ allocation, the effects of transplant policymaking and center variability in patient care. I have an advanced degree in clinical epidemiology, and have expertise with observational study designs, large databases and statistics.

Selected Publications

Bittermann T, Reddy KR: In the era of direct-acting antivirals, liver transplant delisting due to clinical improvement for hepatitis C remains infrequent. Clinical Gastroenterology and Hepatology Epub ahead of print, September 2020.

Wong NZ, Schaubel DE, Reddy KR, Bittermann T : Transplant center experience influences spontaneous survival and waitlist mortality in acute liver failure: an analysis of the UNOS database American Journal of Transplantation Epub ahead of print, August 2020.

Durkin C, Kaplan DE, Bittermann T: T2 Hepatocellular Carcinoma Exception Policies That Prolong Waiting Time Improve the Use of Evidence-based Treatment Practices. Transplantation Direct Epub ahead of print, August 2020.

Mezochow AK, Abt PL, Bittermann T.: Differences in early immunosuppressive therapy among liver retransplantation recipients in a national cohort. Transplantation Epub ahead of print, August 2020.

Bittermann T, Dwinnells K, Chadha S, Wolf MS, Olthoff KM, Serper M : Low health literacy is associated with frailty and reduced likelihood of liver transplant listing: a prospective cohort study Liver Transplantation June 2020.

Bittermann T, Hubbard R, Lewis JD, Goldberg DS: The proportion of Model for End-stage Liver Disease Sodium score attributable to creatinine independently predicts post-transplant survival and renal complications. Clinical Transplantation Epub ahead of print, March 2020.

Bittermann T, Hubbard RA, Lewis JD, Goldberg DS: The use of induction therapy in liver transplantation is highly variable and is associated with posttransplant outcomes. American Journal of Transplantation Dec 2019.

Brahmbhatt M, Prenner S, Bittermann T: Liver transplantation for hepatic epithelioid hemangioendothelioma is facilitated by exception points with acceptable long-term outcomes. Transplantation Sept 2019 Notes: Epub ahead of print.

Bittermann T, Hubbard RA, Lewis JD, Goldberg DS: “Assessing the effectiveness of early maintenance immunosuppression practices in liver transplantation” American Transplant Congress (ASTS & AST); Boston, MA June 2019.

Bittermann T, Goldberg DS: Quantifying the effect of transplanting older donor livers into younger recipients: the need for donor-recipient age matching. Transplantation 102(12): 2033-7, Dec 2018.

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Last updated: 09/30/2020
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