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Hui Li, MD, MS
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Research Associate Professor of Medicine (Hematology-Oncology)
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Department: Medicine
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Contact information
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422 Johnson Pavilion
3a 3610 Hamilton Walk
Philadelphia, PA 19104-6076
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3a 3610 Hamilton Walk
Philadelphia, PA 19104-6076
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Office: 205-253-7007
33 Fax: 215-573-8976
32 Lab: 215-573-6461
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33 Fax: 215-573-8976
32 Lab: 215-573-6461
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Education:
21 9 M.D. 18 (Stomatology) c
4f Capital University of Medical Sciences, Beijing, China, 1992.
21 9 M.S. 1d (Computer Science) c
40 University of Alabama at Birmingham, AL, 2003.
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Permanent link21 9 M.D. 18 (Stomatology) c
4f Capital University of Medical Sciences, Beijing, China, 1992.
21 9 M.S. 1d (Computer Science) c
40 University of Alabama at Birmingham, AL, 2003.
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285 Roark RS, Habib R, Gorman J, Li H, Connell AJ, Bonsignori M, Guo Y, Hogarty MP, Olia AS, Sowers KJ, Zhang B, Bibollet-Ruche F, Bylund T, Callaghan S, Carey JW, Cerutti G, Harris DR, He W, Lewis E, Liu T, Mason RD, Qiao Y, Park Y, Rando JM, Singh A, Wolff JJ, Lei QP, Louder MK, Andrabi R, Doria-Rose NA, Saunders KO, Seaman MS, Haynes BF, Kulp DW, Mascola JR, Roederer M, Pierson TC, Sheng Z, Hahn BH, Shaw GM, Kwong PD, Shapiro L.: Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies. J Exp Med. 222(10), Aug 2025.
233 Morris DJ, Gorman J, Zhou T, Lora J, Connell AJ, Li H, Liu W, Roark RS, Campion MS, Carey JW, Habib R, Li Y, Martella CL, Park Y, Singh A, Sowers KJ, Teng IT, Wang S, Chohan N, Ding W, Lauer C, Lewis E, Mason RD, Rando JM, Peyton L, Schramm CA, Wagh K, Korber B, Seaman MS, Douek DC, Haynes BF, Kulp DW, Roederer M, Hahn BH, Kwong PD, Shaw GM.: Transient glycan shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques. Cell Rep. 44(6), June 2025.
22c Morris DJ, Gorman J, Zhou T, Lora J, Connell AJ, Li H, Liu W, Roark RS, Campion MS, Carey JW, Habib R, Li Y, Martella CL, Park Y, Singh A, Sowers KJ, Teng IT, Wang S, Chohan N, Ding W, Lauer C, Lewis E, Mason RD, Rando JM, Peyton L, Schramm CA, Wagh K, Korber B, Seaman MS, Douek DC, Haynes BF, Kulp DW, Roederer M, Hahn BH, Kwong PD, Shaw GM.: Transient glycan-shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques. Cell Rep. June 2025.
261 Holmes S, Li H, Shen X, Martin M, Tuck R, Chen Y, Giorgi EE, Kirshner HF, Berry M, Van Italie E, Venkatayogi S, Martin Beem JS, Edwards RJ, Mansouri K, Singh A, Kuykendall C, Gurley T, Anthony Moody M, DeNayer N, Demarco T, Denny TN, Wang Y, Evangelous TD, Clinton JT, Hora B, Wagh K, Seaman MS, Saunders KO, Solomotis N, Misamore J, Lewis MG, Wiehe K, Montefiori DC, Shaw GM, Williams WB.: Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques. Nat Commun. November 2024.
33c Rumi Habib, Shahlo O. Solieva, Zi Jie Lin, Sukanya Ghosh, Kelly Bayruns, Maya Singh1, Colby J. Agostino, Nicholas J. Tursi1, Kirsten J. Sowers, Jinwei Huang, Ryan S. Roark, Mansi Purwar, Younghoon Park, Kasirajan Ayyanathan, Hui Li, John W. Carey, Amber Kim1, Joyce Park1, Madison E. McCanna1, Ashwin N. Skelly, Neethu Chokkalingam, Sinja Kriete, Nicholas Shupin, Alana Huynh, Susanne Walker, Niklas Laenger, Jianqiu Du, Jiayan Cui, Beatrice H. Hahn, Ami Patel, Amelia Escolano, Peter D. Kwong, Lawrence Shapiro, Gregory R. Bowman, George M. Shaw, David B. Weiner, Jesper Pallesen, Daniel W. Kulp,: Deep Mining of the Human Antibody Repertoire Identifies Frequent and Immunogenetically Diverse CDRH3 Topologies Targetable by Vaccination. bioRxiv Oct 2024.
260 Skelly, A.N., Li, H., Kreider, E.F., Gristick, B.B., Gavor, E., Li, Y., Keeffe, J.R., Winters, K.J., Campion, M.S., Singh, A., Park, Y., Connell, J., Zhao, C., Ayyanathan, K., Carey, J., Liu, W., Cruickshank, K., Li, J., Hogarty, M.P., Seaman, M.S., Haynes, B.F., Andrabi, R., Weissman, D., Bjorkman, P.J., Hahn, B.H., Shaw, G.M. : Reproducible Elicitation of V3-glycan bNAbs in SHIV-infected macaques: A new molecular blueprint for HIV-1 vaccine design. Duke CHAVD 6th Annual Retreat, Durham, NC Sep 2024 Notes: "Poster Presentation"
135 Michael P. Hogarty, Christian Martella, Edward F. Kreider, Hui Li, Weimin Liu, Ashwin N. Skelly, Nitesh Mishra, Younghoon Park, John Carey, Jesse Connell, Frederic Bibollet-Ruche, Barton F. Haynes, Raiees Andrabi, Drew Weissman, Beatrice H. Hahn, and George M. Shaw 4f : Comparing Germinal Center B Cell Responses to mRNA-LNP Immunization 37 and SHIV Infection with a Germline-Targeting Envelope 66 EMBO annual conference, Las Vegas, NV. Jul 2024 Notes: "Poster Presentation"
258 Holmes, Sommer, Li, Hui, Shen, Xiaoying, Martin, Mitchell, Tuck, Ryan, Berry, Madison, Edwards, Robert J., Mansouri, Katayoun, Evangelous, Tyler, Clinton, John T., Hora, Bhavna, Lella, Muralikrishan, Acharya, Priyamvada, Seaman, Michael S., Saunders, Kevin O., Wiehe, Kevin, Montefiori, David1,, Shaw, George, and Williams, Wilton B.,: Isolation and Characterization of Heterologous Tier 2 HIV-1 Neutralizing Antibodies from SHIV-infected Neonate Macaques HIVR4P conference, Lima, Peru. July 2024 Notes: "Poster Presentation"
387 Ryan S. Roark, Rumi Habib, Jason Gorman, Hui Li, Andrew Jesse Connell, Mattia Bonsignori, Yicheng Guo, Michael P. Hogarty, Adam S. Olia, Kirsten Sowers, Baoshan Zhang, Frederic Bibollet-Ruche, Sean Callaghan, John W. Carey, Gabriele Cerutti, Darcy R. Harris, Wanting He, Emily Lewis, Tracy Liu, Rosemarie D. Mason, Younghoon Park, Juliette M. Rando, Ajay Singh, Jeremy Wolff, Q. Paula Lei, Mark K. Louder, Nicole A. Doria-Rose, Raiees Andrabi, Kevin O. Saunders, Michael S. Seaman, Barton F. Haynes, Daniel W. Kulp, John R. Mascola, Mario Roederer, Zizhang Sheng, Beatrice H. Hahn, George M. Shaw, Peter D. Kwong, and Lawrence Shapiro: HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene. bioRxiv Page: 12:2024.06.11.598384. Jun 2024.
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Selected Publications
30b Habib R, Roark RS, Li H, Connell AJ, Hogarty MP, Wagh K, Wang S, Marchitto L, Skelly AN, Carey JW, Sowers KJ, Ayyanathan K, Plante SJ, Bibollet-Ruche F, Park Y, Agostino CJ, Singh A, Martella CL, Lewis E, Rando JM, Chohan N, Lora J, Ding W, Campion MS, Zhao C, Liu W, Li Y, Li X, Liang B, Chowdhury RR, Amereh K, Van Itallie E, Sheng Z, Ghosh AR, Bar KJ, Williams WB, Wiehe K, Saunders KO, Edwards RJ, Cain DW, Lewis M, Batista FD, Burton DR, Andrabi R, Kulp DW, Haynes BF, Korber B, Shapiro L, Kwong PD, Hahn BH, Shaw GM.: Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development. bioRxiv [Preprint](652068), September 2025.285 Roark RS, Habib R, Gorman J, Li H, Connell AJ, Bonsignori M, Guo Y, Hogarty MP, Olia AS, Sowers KJ, Zhang B, Bibollet-Ruche F, Bylund T, Callaghan S, Carey JW, Cerutti G, Harris DR, He W, Lewis E, Liu T, Mason RD, Qiao Y, Park Y, Rando JM, Singh A, Wolff JJ, Lei QP, Louder MK, Andrabi R, Doria-Rose NA, Saunders KO, Seaman MS, Haynes BF, Kulp DW, Mascola JR, Roederer M, Pierson TC, Sheng Z, Hahn BH, Shaw GM, Kwong PD, Shapiro L.: Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies. J Exp Med. 222(10), Aug 2025.
233 Morris DJ, Gorman J, Zhou T, Lora J, Connell AJ, Li H, Liu W, Roark RS, Campion MS, Carey JW, Habib R, Li Y, Martella CL, Park Y, Singh A, Sowers KJ, Teng IT, Wang S, Chohan N, Ding W, Lauer C, Lewis E, Mason RD, Rando JM, Peyton L, Schramm CA, Wagh K, Korber B, Seaman MS, Douek DC, Haynes BF, Kulp DW, Roederer M, Hahn BH, Kwong PD, Shaw GM.: Transient glycan shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques. Cell Rep. 44(6), June 2025.
22c Morris DJ, Gorman J, Zhou T, Lora J, Connell AJ, Li H, Liu W, Roark RS, Campion MS, Carey JW, Habib R, Li Y, Martella CL, Park Y, Singh A, Sowers KJ, Teng IT, Wang S, Chohan N, Ding W, Lauer C, Lewis E, Mason RD, Rando JM, Peyton L, Schramm CA, Wagh K, Korber B, Seaman MS, Douek DC, Haynes BF, Kulp DW, Roederer M, Hahn BH, Kwong PD, Shaw GM.: Transient glycan-shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques. Cell Rep. June 2025.
261 Holmes S, Li H, Shen X, Martin M, Tuck R, Chen Y, Giorgi EE, Kirshner HF, Berry M, Van Italie E, Venkatayogi S, Martin Beem JS, Edwards RJ, Mansouri K, Singh A, Kuykendall C, Gurley T, Anthony Moody M, DeNayer N, Demarco T, Denny TN, Wang Y, Evangelous TD, Clinton JT, Hora B, Wagh K, Seaman MS, Saunders KO, Solomotis N, Misamore J, Lewis MG, Wiehe K, Montefiori DC, Shaw GM, Williams WB.: Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques. Nat Commun. November 2024.
33c Rumi Habib, Shahlo O. Solieva, Zi Jie Lin, Sukanya Ghosh, Kelly Bayruns, Maya Singh1, Colby J. Agostino, Nicholas J. Tursi1, Kirsten J. Sowers, Jinwei Huang, Ryan S. Roark, Mansi Purwar, Younghoon Park, Kasirajan Ayyanathan, Hui Li, John W. Carey, Amber Kim1, Joyce Park1, Madison E. McCanna1, Ashwin N. Skelly, Neethu Chokkalingam, Sinja Kriete, Nicholas Shupin, Alana Huynh, Susanne Walker, Niklas Laenger, Jianqiu Du, Jiayan Cui, Beatrice H. Hahn, Ami Patel, Amelia Escolano, Peter D. Kwong, Lawrence Shapiro, Gregory R. Bowman, George M. Shaw, David B. Weiner, Jesper Pallesen, Daniel W. Kulp,: Deep Mining of the Human Antibody Repertoire Identifies Frequent and Immunogenetically Diverse CDRH3 Topologies Targetable by Vaccination. bioRxiv Oct 2024.
260 Skelly, A.N., Li, H., Kreider, E.F., Gristick, B.B., Gavor, E., Li, Y., Keeffe, J.R., Winters, K.J., Campion, M.S., Singh, A., Park, Y., Connell, J., Zhao, C., Ayyanathan, K., Carey, J., Liu, W., Cruickshank, K., Li, J., Hogarty, M.P., Seaman, M.S., Haynes, B.F., Andrabi, R., Weissman, D., Bjorkman, P.J., Hahn, B.H., Shaw, G.M. : Reproducible Elicitation of V3-glycan bNAbs in SHIV-infected macaques: A new molecular blueprint for HIV-1 vaccine design. Duke CHAVD 6th Annual Retreat, Durham, NC Sep 2024 Notes: "Poster Presentation"
135 Michael P. Hogarty, Christian Martella, Edward F. Kreider, Hui Li, Weimin Liu, Ashwin N. Skelly, Nitesh Mishra, Younghoon Park, John Carey, Jesse Connell, Frederic Bibollet-Ruche, Barton F. Haynes, Raiees Andrabi, Drew Weissman, Beatrice H. Hahn, and George M. Shaw 4f : Comparing Germinal Center B Cell Responses to mRNA-LNP Immunization 37 and SHIV Infection with a Germline-Targeting Envelope 66 EMBO annual conference, Las Vegas, NV. Jul 2024 Notes: "Poster Presentation"
258 Holmes, Sommer, Li, Hui, Shen, Xiaoying, Martin, Mitchell, Tuck, Ryan, Berry, Madison, Edwards, Robert J., Mansouri, Katayoun, Evangelous, Tyler, Clinton, John T., Hora, Bhavna, Lella, Muralikrishan, Acharya, Priyamvada, Seaman, Michael S., Saunders, Kevin O., Wiehe, Kevin, Montefiori, David1,, Shaw, George, and Williams, Wilton B.,: Isolation and Characterization of Heterologous Tier 2 HIV-1 Neutralizing Antibodies from SHIV-infected Neonate Macaques HIVR4P conference, Lima, Peru. July 2024 Notes: "Poster Presentation"
387 Ryan S. Roark, Rumi Habib, Jason Gorman, Hui Li, Andrew Jesse Connell, Mattia Bonsignori, Yicheng Guo, Michael P. Hogarty, Adam S. Olia, Kirsten Sowers, Baoshan Zhang, Frederic Bibollet-Ruche, Sean Callaghan, John W. Carey, Gabriele Cerutti, Darcy R. Harris, Wanting He, Emily Lewis, Tracy Liu, Rosemarie D. Mason, Younghoon Park, Juliette M. Rando, Ajay Singh, Jeremy Wolff, Q. Paula Lei, Mark K. Louder, Nicole A. Doria-Rose, Raiees Andrabi, Kevin O. Saunders, Michael S. Seaman, Barton F. Haynes, Daniel W. Kulp, John R. Mascola, Mario Roederer, Zizhang Sheng, Beatrice H. Hahn, George M. Shaw, Peter D. Kwong, and Lawrence Shapiro: HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene. bioRxiv Page: 12:2024.06.11.598384. Jun 2024.
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