McKay Orthopaedic Research Laboratory

Welcome to Heo Laboratory

The Heo Lab is focused on nuclear mechanobiology and tissue engineering to develop new therapeutic strategies for musculoskeletal repair and regeneration. Our research team explores the feedback between the biophysical environment and cell biology in the context of musculoskeletal tissue remodeling (with development, disease, degeneration, or repair). We also develop innovative methods to enable precise control of the cellular microenvironment and utilize sophisticated experimental techniques [e.g., Super-resolution stochastic optical reconstruction microscopy (STORM)] to address our fundamental questions about how biophysical cues regulate cellular behaviors at the nanoscale. In addition, our team aims to expand our findings and knowledge to engineer complex functional tissue constructs for regenerative medicine applications using fabrication techniques (e.g., electrospinning and 3D Bioprinting).

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Lab News

Congratulations to the Heo Lab!
September 20, 2022
Congratulations to Dr.Heo and Heo Lab for being awarded NIH/NIAMS R01 Grant Award for 2022-2027!

Welcome to The Heo Lab, Tyler Blanch!
September 12, 2022
Welcome to our Biotechnology grad student Tyler Blanch!

Congratulations to the Heo Lab!
September 09, 2022
Congratulations to Dr.Heo and Heo Lab for being awarded NIH/NHLBI R56 Grant Award for 2022-2023!

Congratulations Molly and Ellen!
August 29, 2022
We are very excited that Molly and Ellen are starting their PhD in the Penn Bioengineering program this fall!

Congratulations to Su Chin Heo and Co-authors!
August 22, 2022
Congratulations to Su Chin Heo and Co-authors for their paper 'Aberrant chromatin reorganization in cells from diseased fibrous connective tissue in response to altered chemomechanical cues’ now published in Nature Biomedical Engineering. Nice work!

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