Shore Laboratory

Deyu Zhang

Research Specialist
University of Pennsylvania


Beijing, China


B.S. Biochemistry, 1983, Nanjing University

Areas of Special Interest

Molecular Biology, Mouse Model

Peer-Reviewed Publications

Chakkalakal, S.A., K. Uchibe, M. Convente, D. Zhang, A. Economides, F.S. Kaplan, M. Pacifici, M. Iwamoto, E.M. Shore (2016). Palovarotene inhibits heterotopic ossification and maintains limb mobility and growth in mice with the human ACVR1R206H FOP mutation. J. Bone Min. Res. 31, 1666-1675.

Ramaswamy, G., H. Kim, D. Zhang, V. Lounev, J.Y. Wu, Y. Choi, F.S. Kaplan, R.J. Pignolo, and E.M. Shore (2017). Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways. Scientific Reports 7, 45140; doi:10.1038/srep45140.

Convente, M.R., S.A. Chakkalakal, E. Yang, R.J. Caron, D. Zhang, T. Kambayashi, F.S. Kaplan, and E.M. Shore (2018). Depletion of mast cells and macrophages impairs heterotopic ossification in an Acvr1R206H mouse model of fibrodysplasia ossificans progressiva. J. Bone Min. Res., 33, 269-282. Issue cover image.

Ramaswamy, G., J. Fong, N. Brewer, H. Kim, D. Zhang, Y. Choi, F.S. Kaplan, and E.M. Shore (2018). Ablation of Gsa signaling in osteoclast progenitor cells adversely affects skeletal bone maintenance. Bone 109, 86-90.

Girish Ramaswamy, Hyunsoo Kim, Deyu Zhang, Vitali Lounev, Joy Wu, Yongwon Choi, Frederick Kaplan, Robert Pignolo, and Eileen M Shore; Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways, Scientific Reports, Accepted, 2017

Salin A Chakkalakal, Kenta Uchibe, Michael R Convente, Deyu Zhang, Aris N Economides, Frederick S Kaplan, Maurizio Pacifici, Masahiro Iwamoto, and Eileen M Shore; Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice with the Human ACVR1 R206H Fibrodysplasia Ossificans Progressiva (FOP) Mutation. Journal of Bone and Mineral Research, Vol. 31 (9), 1666-1675, September 2016

SA Chakkalakal, D Zhang, AL Culbert, MR Convente, RJ Caron, AC Wright, A DA Maidment, FS Kaplan, EM Shore. An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva. Journal of Bone and Mineral Research, Vol. 27(8), 1746-1756, July 2012.

JJ Liu, E Russell, D Zhang, FS Kaplan, RJ Pignolo and EM. Shore. Paternally Inherited Gs Mutation Impairs Adipogenesis and Potentiates a Lean Phenotype In Vivo. Stem Cells, Vol. 30(7), P1477-1485, June, 2012.

Deyu Zhang and L.S. Walter, Conformational Isomers of Insect Odorant-Binding Proteins, Archives of Biochemistry and Biophysics, 2002, 397(1):99-105.

V. Nong, M. Arahira, V. Phan, C. Kim, Deyu Zhang et al. Molecular Cloning and Characterization of a Group II Chaperonin Delta-Subunit from Soybean, Journal of Biochemistry, 2002, 132(2):291-300.

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