Robert Tower, Ph.D
Post-doctoral Researcher
Country
Canada
Education
2003-2008: Bachelor of Science (Specialization in Molecular Genetics) University of Alberta (Canada)
2008-2012: Master of Science (Cell Biology) University of Alberta (Canada)
2012-2015: Ph.D. in Natural Sciences. Mentor: Dr. Claus C. Glüer, Department of Radiology and Neuroradiology, Christian Albrechts University (Germany)
Publications
Dotterweich J, Schlegelmilch K, Alexander K, Beate G, Doris S, Zeck S, Tower RJ, Ebert R, Jakob F, Scutze N. 2016. Conatct of myeloma cells induces a characteristic transcriptome signature in skeletal precursor cells-implications for myeloma bone disease. Bone 93:155- 166
Stelmach-Mardas M, Iqbal K, Mardas M, Schwingshackl L, Walkowiak J, Tower RJ, Boeing H. 2016. Synchronic inverse seasonal rhythmus of energy density of food intake and sleep quality: a contribution to chrono-nutrition from a Polish adult population. Eur J Clin Nutr doi: 10.1038/ejcn.2016.229
Tower RJ*, Schem C*, Kneissl P, Rambow AC, Campbell GM, Desel C, Damm T, Heilmann T, Fuchs S, Zuharya M, Trauzold A, Gluer CC, Schott S, Tiwari S. 2016. Pharmacologically inactive bisphosphonates as an alternative strategy for targeting osteoclasts: in vivo assessment of 5-fluorodeoxyuridine-alendronate in a preclinical model of breast cancer bone metastases. J Bone Miner Res doi: 10.1002/jbmr.3012
Stelmach-Mardas M, Mardas M, Iqbal K, Tower RJ, Piorunek T. 2016. The association between depression, quality of life and nutrition in newly diagnosed obstructive sleep apnea patients. Health Qual Life Outcomes 14(1):111
Tower RJ*, Dotterweich J*, Brandl, A, Müller M, Hofbauer LC, Beilhack A, Ebert R, Glüer CC, Tiwari S, Schütze N, Jakob F. 2016. The KISS1 receptor as an in vivo microenvironment imaging biomarker of multiple myeloma bone disease. PLOS ONE 11(5):e0155087
Schott S, Valett S, Tower RJ, Noor S, Tiwari S, Schem C, Busch C. 2015. In vitro and in vivo toxicity of 5-FdU-alendronate, a novel bone-seeking duplex drug. Invest New Drugs 33(4):846-826
Tower RJ*, Fritsche H*, Heilmann T*, Hauser C, von Au A, El-Sheikh D, Campbell GM, Alp G, Schewe D, Hübner S, Tiwari S, Kownatzki D, Boretius S, Adam D, Jonat W, Becker T, Glüer CC, Zöller M, Kalthoff H, Schem C, Trauzold A. 2015. TRAIL-R2 promotes skeletal metastasis in a breast cancer xenograft mouse model. Oncotarget 6(11):9502- 9516
Chang J, Klute MJ, Tower RJ, Mast FD, Dacks JB, Rachubinski RA. 2015. An ancestral role in peroxisome assembly is retained by the divisional peroxin Pex11 in the yeast Yarrowia lipolytica. J Cell Sci 128(7):1327-1340
Tower RJ*, Campbell GM*, Müller M, Glüer CC, Tiwari S. 2015. Utilizing time-lapse microCT-correlated bisphosphonate binding kinetics and soft tissue-derived input functions to differentiate site-specific changes in bone metabolism in vivo. Bone74:171-181
Dotterweich J, Ebert R, Kraus S, Tower RJ, Jakob F, Schütze N. 2014. Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells. Cell Commun Signal 12(36)
Tower RJ, Campbell GM, Müller M, Will O, Glüer CC, Tiwari S. 2014. Binding kinetics of a fluorescently-labeled bisphosphonate as a tool for dynamic monitoring of bone mineral deposition in vivo. J Bone Miner Res 29(9):1993-2003
Ranta TM, Suojanen J, Penate-Medina O, Will O, Tower RJ, Glüer CC, Kairemo K, Gahmberg CG, Koivunen E, Sorsa T, Saris PEJ and Reunanen J. 2014. In vivo targeting of activated leukocytes by B2-integrin binding peptide. Mol Diagn Ther 18:39-44
Chang J, Tower RJ, Lancaster DL and Rachubinski RA. 2013. Dynein light chain interaction with the peroxisomal import docking complex modulates peroxisome biogenesis in yeast. J Cell Sci 126(20):4698-706
Gao T, Bowlby E, Tong Y, Wu JT, Wong K, Tower RJ, Pang X and Li X. 2012. Evaluation of the matrix effect of thermophilic anaerobic digestion on inactivation of infectious laryngotracheitis virus using real-time PCR and viral cell culture. Bioresour Technol 110:692-696
Tower RJ, Fagarasanu A, Aitchison JD and Rachubinski RA. 2011. The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast. Mol Biol Cell 22(10):1727-38
