Xiaoyu Xu, Ph.D.
Postdoctoral Fellow
Hometown
Beijing, China
Education
Ph.D., Biomedical Engineering, 2022, Purdue University
M.S., Biomedical Engineering, 2016, New York University
B.D., Bioengineering, 2013, Capital Normal University, Beijing, China
Hobbies
Meditation, Tennis, Yoga, and Chinese classical dance.
Research Areas of Interest
Age-related osteoporosis, Sex hormonal regulation, osteocyte biology, and bone biomechanics
Honors/Awards
ASBMR Young Investigator Award, American Society of Bone and Mineral Research Annual Meeting, 2021
Summer Research Grant, Weldon School of Engineering, Purdue University, 2020
Best Pre-Doctoral Talk Award, Orthopaedic Research Society Great Lakes/Midwest Regional Symposium: Orthopaedic Research from Bench to Bedside, 2019
Young Investigator Travel Grant, American Society for Bone and Mineral Research Annual Meeting, 2019
Leslie A. Geddes Fellowship, Purdue University, 2016-2017
Scholarship, Tandon School of Engineering, New York University, 2014-2015
Publications
- Brennan T. Flannery, Xiaoyu Xu, Brian T. Golz, and Russell P. Main, "Automated bone cell classification for confocal laser scanning microscopy volumes," Opt. Continuum 1, 1364-1374 (2022)
- Haisheng Yang, Xiaoyu Xu, Whitney Bullock, Russell P. Main., Adaptive Changes in Micromechanical Environments of Cancellous and Cortical Bone in Response to In Vivo Loading and Disuse, Journal of Biomechanics, 89 (2019) 85-94.
- Qianbin Wang, Weiyi Qian, Xiaoyu Xu, Apratim Bajpai, Weiqiang Chen., Energy-Mediated Machinery Drives Cellular Mechanical Allostasis, Advanced Material, 2019, 1900453
Invited Seminar
Aug 2021 Tulane University School of Medicine, New Orleans, LA
Oct 2021 Indiana Center for Musculoskeletal Health, Indiana University, Indianapolis, IN
Nov 2021 University of California San Francisco, San Francisco, CA (online seminar)
Talks
- Xiaoyu Xu, Haisheng Yang, Whitney A. Bullock, Maxime A. Gallant, Teresita M. Bellido, Russell P. Main. Estrogen Receptor β in Osteocytes (Ot-ERβ) Exerts Sex- and Age-dependent Functions on Bone Turnover and Load-induced Skeletal Adaptive Response in Mice. ASBMR Annual Meeting, San Diego, CA, 2021. Oral Poster Presentation
- Xiaoyu Xu, Haisheng Yang, Rachel E. Embry, Whitney A. Bullock, Teresita M. Bellido, Russell P. Main. The role of osteocyte estrogen receptor β in age-related bone turnover and skeletal mechanotransduction differs in younger and adult male mice. Short Talk Podium Presentation at the Orthopaedic Research Society (ORS) Great Lakes/Midwest Regional Symposium: Orthopaedic Research from Bench to Bedside. Rush University Medical Center, Chicago, IL, 2019. Won ‘the Best Pre-Doctoral Talk Award’.
Abstract
- Xiaoyu Xu, Haisheng Yang, Whitney A. Bullock, Maxime A. Gallant, Teresita M. Bellido, Russell P. Main. Estrogen Receptor β in Osteocytes (Ot-ERβ) Exerts Sex- and Age-dependent Functions on Bone Turnover and Load-induced Skeletal Adaptive Response in Mice. ASBMR Annual Meeting, San Diego, CA, 2021. Plenary Poster Presentation
- Xiaoyu Xu, Brian T. Golz, Brennan T. Flannery, Maxime A. Gallant, Whitney A. Bullock, James A. Schaber, Teresita M. Bellido, Fredrick M. Pavalko, Eric A. Nauman, Sherry L. Harbin, Russell Main. The Development of a Novel Collagen-Mineral 3-Dimensional (3D) In Vitro Culture System for Reproducing Osteocyte Differentiation and Tissue Mineralization. ASBMR Annual Meeting, San Diego, CA, 2021.
- Brennan Flannery, Xiaoyu Xu, Russell Main. Automated Segmentation of Vertebral Cancellous and Cortical Bone in Mouse Spines Using Deep Learning UNET Model. ORS 2021 Virtual Meeting.
- Brennan Flannery, Xiaoyu Xu, Brian Golz, Russell Main. Automated Classification of Bone Cells in Laser Scanning Confocal Microscopy Volumes. Biomedical Engineering Society (BMES) 2020 Virtual Annual Meeting.
- Xiaoyu Xu, Haisheng Yang, Rachel E. Embry, Whitney A. Bullock, Teresita M. Bellido, Russell P. Main. The role of osteocyte estrogen receptor β in age-related bone turnover and skeletal mechanotransduction differs in younger and adult male mice. ASBMR Annual Meeting. Orlando, FL, 2019.
- Xiaoyu Xu, Haisheng Yang, Rachel E. Embry, Whitney A. Bullock, Teresita M. Bellido, Russell P. Main. The role of osteocyte estrogen receptor β in bone turnover and skeletal mechanotransduction differs in male and female mice. Advancing Health of the Engineering-Medicine Partnership between the Purdue College of Engineering and the Indiana University School of Medicine. Indianapolis, IN, 2019.
- Xiaoyu Xu, Haisheng Yang, Rachel E. Embry, Whitney A. Bullock, Teresita M. Bellido, Russell P. Main. The role of osteocyte estrogen receptor β in bone turnover and skeletal mechanotransduction differs in male and female mice. David Van Sickle Musculoskeletal Days. West Lafayette, IN, 2018.
- Hannah Cebull, Rucha Joshi, Andrew Brightman, Asem Aboelzahab, Joseph Muskat, Xiaoyu Xu, and Minku Kim. Early Implementation of Project-based, Self-learning Module at Sophomore Level to Develop CAD Skills in BME. BMES Annual Meeting in Atlanta, GA, 2018.
- Xiaoyu Xu, Haisheng Yang, Rachel E. Embry, Whitney A. Bullock, Teresita M. Bellido, Russell P. Main. The role of osteocyte estrogen receptor β in bone turnover and skeletal mechanotransduction differs in male and female mice. ASBMR Annual Meeting in Montréal, Quebec, Canada, 2018.
- Qianbin. Wang, Xiaoyu Xu, Apratim Bajpai, Roy Chen, Weiqiang Chen. Cellular Mechano-adaptation: When Biology Meets Mechanics. Honorary poster presentation at the Cellular and Molecular Bioengineering Meeting (CMBM) in the Big Island of Hawaii, HI, 2017.
- Weiyi Qian, Qianbin Wang, Xiaoyu Xu, Weiqiang Chen. Mechanical Phenotyping of Inflammatory Breast Cancer Stem Cells. BMES Annual Meeting in Minneapolis, MN, 2016.
- Qianbin Wang, Xiaoyu Xu, Caroline Kopfler, Weiqiang Chen. Subcellular Cytoskeleton Architecture Regulates Mechano-homeostasis of Vascular Smooth Muscle Cells. BMES Annual Meeting in Minneapolis, MN, 2016.