Yihan Li
Graduate Student in Bioengineering
University of Pennsylvania
Hometown
Jiangsu, China
Education
M.S.E. in Materials Science and Engineering, 2015, University of Pennsylvania
B.E. Materials Science and Engineering, 2013, South China University of Technology, China
Areas of Special Interest
Bone-repair materials, nano-scale materials
Hobbies
Traveling, playing Zheng (Chinese traditional instrument)
Honors and Awards
Young Investigator Travel Grant, American Society of Bone and Mineral Research, 2019
1st place of Penn Center for Musculoskeletal Disorders Symposium Poster Competition, 2019
Publications
Li Y, de Bakker CMJ, Lai X, Zhao H, Parajuli A, Tseng WJ, Pei S, Tan M, Chung R, Wang L, Liu XS. Maternal Bone Adaptation to Mechanical Loading during Pregnancy, Lactation, and Post-Weaning Recovery. Bone. 2021
Lai X, Chung R, Li Y, Liu XS, Wang L. Lactation Alters Fluid Flow and Solute Transport in Maternal Skeleton: A Multiscale Modeling Study on the Effects of Microstructural Change and Loading Frequency. Bone. 2021
Li Y, Tseng WJ, de Bakker CMJ, Zhao H, Chung R, Liu XS. Peak Trabecular Bone Microstructure Predicts Rate of Estrogen-Deficiency-Induced Bone Loss in Rats. Bone. 2021
Fung A, Shetye S, Li Y, Zhou Y, Liu X, Soslowsky LJ. Pregnancy and Lactation Impair Subchondral Bone Leading to Reduced Rat Supraspinatus Tendon Failure. J Biomech Eng. 2020
de Bakker CM, Li Y, Zhao H, Leavitt L, Tseng WJ, Lin T, Tong W, Qin L, Liu XS. Structural Adaptations in the Rat Tibia Bone Induced by Pregnancy and Lactation Confer Protective Effects Against Future Estrogen Deficiency. J Bone Miner Res. 2018
de Bakker CMJ, Zhao H, Tseng WJ, Li Y, Altman-Singles AR, Liu Y, Leavitt L, Liu XS. Effects of reproduction on sexual dimorphisms in rat bone mechanics. J Biomech. 2018; 77:40-47.
de Bakker CMJ, Tseng WJ, Li Y, Zhao H, Altman-Singles AR, Jeong Y, Robberts J, Han L, Kim DG, X. Sherry Liu. Reproduction Differentially Affects Trabecular Bone Depending on Its Mechanical Versus Metabolic Role. J Biomech Eng. 2017; 139(11).
de Bakker CMJ, Tseng WJ, Li Y, Zhao H, Liu XS. Clinical Evaluation of Bone Strength and Fracture Risk. Current Osteoporosis Report. 2017; 15(1): 32-42.
de Bakker CMJ, Altman-Singles AR, Li Y, Tseng WJ, Li C, Liu XS. Adaptations in the Microarchitecture and Load Distribution of Maternal Cortical and Trabecular Bone in Response to Multiple Reproductive Cycles in Rats. Journal of Bone and Mineral Research. 2017; 32(5):1014-1026.
Abstracts
Li Y, de Bakker CMJ, Zhao H, Parajuli A, Tseng WJ, Pei S, Meng T, Chung R, Wang L, Liu XS. Maternal Bone Adaptation to Mechanical Loading During Pregnancy, Lactation, and Post-weaning Recovery. Summer Biomechanics, Bioengineering and Biotransport Conference, June 14-18, 2021.
Li Y, Parajuli A, de Bakker CMJ, Chung R, Zhao H, Tseng WJ, Wang L, Liu XS. Maternal Bone Adaptation To Mechanical Loading During Pregnancy, Lactation, And Post-weaning Recovery. Orthopaedic Research Society Annual Meeting; February 12-16, 2021.
Li Y, Zhou Y, de Bakker CMJ, Zhao H, Wang L, Zhong L, Qin L, Liu XS. Effects Of Reproduction And Lactation On Osteogenic And Adipogenic Differentiation Potentials Of Bone Marrow Mesenchymal Stem Cells. Orthopaedic Research Society Annual Meeting; February 12-16, 2021.
Tseng WJ, Wang W, Zhao H, Bennett A, Mariani L, Li Y, Dyment N, Kim DG, Turner K, Liu XS. Differences in Material Properties of Trabecular Bone Tissue from Modeling- and Remodeling- Based Bone Formation in Rats. American Society of Bone and Mineral Research Annual Meeting; September 11-14, 2020.
Chung R, Li Y, de Bakker CMJ, Osuna CA, Leggin J, Davis Z, Wang L, Liu XS. Delineating the Effects of Pregnancy and Lactation on Rat Maternal Bone Responses to Future Estrogen Deficiency. (accepted as NIRA finalist) Orthopaedic Research Society 2020 Annual Meeting. Phoenix, AZ. February 8-11, 2020
Li Y, Zhou Y, de Bakker CMJ, Zhao H, Wang L, Zhong L, Yao L, Ling Q, Liu XS. Interactive Effects of Lactation History and Estrogen Status on Rat Maternal Bone Cells.American Society of Bone and Mineral Research, Orlando, Florida, September 20-23, 2019.
Li Y, Parajuli A, de Bakker CMJ, Zhao H, Tseng WJ, Chung R, Wang L, Liu XS. Effects of Reproduction and Lactation on Rat Maternal Bone Mechano-Responsiveness and Osteocyte Microenvironment. Summer Biomechanics, Bioengineering, and Biotransport Conference. Seven Springs, PA. June 25-28, 2019.
Li Y, Bakker CMJ, Tseng WJ, Zhao H, Parajuli A, Wang L, Liu XS. Peri-Lacunar/Canalicular (PLC) Remodeling Enhances Mechano-Sensitivity in Rat Maternal Bone when Subjected to Estrogen Deficiency. American Society of Bone and Mineral Research, Montréal, Québec, Canada, September 28-October 1, 2018.
Zhao H, Tseng WJ, Lee TJ, Lee W, Li Y, de Bakker CMJ, Leahy T, Liu XS. Alternating Parathyroid Hormone (PTH) and Alendronate Treatment Regimens Further Improve the Efficacy of Daily and Cyclic PTH Regimens in Osteoporosis Therapy. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 10-13, 2018.
Li Y, de Bakker CMJ, Meng T, Tseng WJ, Zhao H, Parajuli A, Wang L, Liu XS. Effects of Reproduction and Lactation on Maternal Bone Mechano-Sensitivity. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 10-13, 2018.
de Bakker CMJ, Leavitt L, Zhao H, Li Y, Krickus C, Huang M, Tseng WJ, Liu XS. Microarchitectural Adaptations in Rat Maternal Bone Induced by Pregnancy and Lactation Exert Protective Effects against Future Estrogen Deficiency. Orthopaedic Research Society Annual Meeting, New Orleans, LA, March 10-13, 2018.
Li Y, Tseng WJ, de Bakker CMJ, Zhao H, Liu XS. Peak Trabecular Bone Microarchitecture But Not Bone Mass Predicts Rate of Estrogen-Deficiency-Induced Bone Loss. American Society of Bone and Mineral Research, Denver, CO, September 7-11, 2017.
Tseng WJ, Zhao H, Lee W, Liu Y, Li Y, de Bakker CMJ, Qin L, Liu XS. Cyclic Treatment Regimen Rescues Parathyroid Hormone (PTH) Discontinuation-Induced Bone Loss and Microarchitecture Deterioration. American Society of Bone and Mineral Research, Denver, CO, September 7-11, 2017. Plenary Poster.
Li Y, Tseng WJ, de Bakker CMJ, Zhao H, Liu XS. Relationship between peak microstructure properites and estrogen-deficiency-induced bone loss. Summer Biomechanics, Bioengineering and Biotransport Conference, Tucson, AZ, June 21-24, 2017.
Zhao H, Tseng WJ, Lee W, Liu Y, Li Y, de Bakker CMJ, Liu XS. Effects of daily and cyclic parathyoid hormone treatment regimens on bone in OVX rats. Summer Biomechanics, Bioengineering and Biotransport Conference, Tucson, AZ, June 21-24, 2017.
Li Y, Peng G, Tseng WJ, de Bakker CM, Chandrasekaran P, Jeong YH, Kim DG, Han L, Liu XS. Effects of reproduction and lactation on maternal bone tissue mechanical properties at different length scales. Summer Biomechanics, Bioengineering and Biotransport Conference, National Harbor, MD, June 29-July 2, 2016
Tseng WJ, Lee W, Tong W, Wang L, Ma X, Zhao H, Li Y, Chang CC, de Bakker CM, Qin L, Liu XS. Skeletal Responses to the Discontinuation of Intermittent Parathyroid Hormone (PTH) Treatment in Intact and Ovariectomized Rats. American Society for Bone and Mineral Research Annual Meeting, Atlanta, GA, September 12-15, 2016. Submitted.
Tseng WJ, Li Y, de Bakker CMJ, Chandrasekaran P, Jeong Y, Kim DG, Han L, Liu XS. Osteocyte Modulation of Local Bone Tissue Mechanical Properties during Reproduction and Lactation. Orthopaedic Research Society Annual Meeting, Orlando, FL, March 5-8, 2016.