Kathryn Leigh Wofford

faculty photo
Assistant Professor of Neurosurgery
Investigator, Corporal Michael J. Crescenz VA Medical Center
Department: Neurosurgery

Contact information
3900 Woodland Avenue
Philadelphia, PA 19104
Graduate Group Affiliations
Education:
BA (Biophysics and Psychology)
Austin College, 2012.
MS (Biomedical Engineering)
Drexel University, 2015.
PhD (Biomedical Engineering)
Drexel University, 2019.
Post-Graduate Training
Postdoctoral Fellow, University of Pennsylvania, 2019-2024.
Certifications
Compass Foundational Training and Mentoring Program, 2023.
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Description of Research Expertise

Neuroinflammation, traumatic brain injury, immunoengineering, cellular therapies, biomaterials

Selected Publications

Wofford KL, Browne KD, Loane DJ, Meaney DF, Cullen DK: Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs. Journal of Neuroinflammation 21(1): 324, Dec 2024.

Song H, Tomasevich A, Paolini A, Browne KD, Wofford KL, Kelley B, Kantemneni E, Kennedy J, Dolle JP, Cullen DK, Smith DH: Sex differences in the extent of acute axonal pathologies after experimental concussion. Acta Neuropathologica 147(1): 79, May 2024.

Harris JP, Mietus CJ, Browne KD, Keating CE, Brown DP, Wofford KL, Johnson BN, Wolf JA, Smith DH, Cohen AS, Duda JE, Cullen DK: Neuronal somatic plasmalemmal permeability and dendritic beading caused by head rotational traumatic brain injury in pigs – an exploratory study. Frontiers in Cellular Neuroscience 17, July 2023.

Struzyna LA, Browne KD, Burrell JC, Gordián-Vélez WJ, Wofford KL, Kaplan HM, Murthy NS, Chen HI, Duda JE, España RA, Cullen DK: Axonal Tract Reconstruction Using a Tissue-Engineered Nigrostriatal Pathway in a Rat Model of Parkinson's Disease International Journal of Molecular Sciences 23(22): 13985, Nov 2022.

O’Donnell JC, Swanson RL, Wofford KL, Grovola MR, Purvis EM, Petrov D, Cullen DK: Emerging Approaches for Regenerative Rehabilitation following Traumatic Brain Injury. Regenerative Rehabilitation - From Basic Science to the Clinic Sarah M. Greising & Jarrod A Call (eds.). Springer Nature, Page: 409-459, Jun 2022.

Wofford KL, Shultz RB, Burrell JC, Cullen DK: Neuroimmune Interactions and Immunoengineering Strategies in Peripheral Nerve Repai. Progress in Neurobiology 208: 102172, Jan 2022.

Wofford KL, Grovola MR, Adewole DO, Browne KD, Putt ME, O’Donnell JC, Cullen DK: Relationships between injury kinematics, neurological recovery, and pathology following concussion. Brain Communications 3(4): fcab268, Nov 2021.

Grovola MR, Paleologos N, Brown DP, Tran N, Wofford KL, Harris JP, Browne KD, Shewokis PA, Wolf JA, Cullen DK, Duda JE.: Diverse changes in microglia morphology and axonal pathology during the course of 1 year after mild traumatic brain injury in pigs. Brain Pathology 31(5): e12953, Sep 2021.

Huber CM, Patton DA, Wofford KL, Margulies SS, Cullen DK, Arbogast KB: Laboratory assessment of a headband-mounted sensor for measurement of head impact rotational kinematics. Journal of Biomechanical Engineering 143(2): 024502, Feb 2021.

Grovola MR, Paleologos N, Wofford KL, Harris JP, Browne KD, Johnson VE, Duda JE, Wolf JA, Cullen DK.: Mossy cell hypertrophy and synaptic changes in the hilus following mild diffuse traumatic brain injury in pigs. Journal of Neuroinflammation 17(1): 44, Jan 2020.

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Last updated: 06/30/2025
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