Chris Kegelman, Ph.D.
Graduate Student
University of Pennsylvania
Hometown
Yorktown, Virginia
Education
B.S. Biomedical Engineering, 2015, University of Virginia
Areas of Interest
Bone Biology, Tissue Regeneration, Biomechanics
Chris joined the McKay Orthopaedic Research Laboratory in the summer of 2017 and is working on completing his graduate work in the Department of Bioengineering. Outside of the lab, he enjoys traveling, biking and playing water polo.
Publications
Pearson HB, Mason DE, Kegelman CD, Zhao L, Dawahare JH, Kacena MA, Boerckel JD. Effects of Bone Morphogentic Protein-2 on neovascularization during large bone defect regeneration. Tissue Engineering Part A. 2019 June
Kegelman CD, Mason DE, Dawahare JH, Horan DJ, Vigil GD, Howard SS, Robling AG, Bellido TM, Boerckel JD. Skeletal cell YAP and TAZ combinatorially promote bone development. The FASEB Journal. 2018 Jan
Martin KS, Kegelman CD, Virgilio KM, Passipieri JA, Christ GJ, Blemker SS, Peirce SM. In silico and in vivo experiments reveal M-CSF injections accelerate regeneration following muscle laceration. Annals of Biomedical Engineering. 2017 Mar
Conference Abstracts and Presentations
Kegelman CD, Coulombe JC, Jordan KM, Horan DJ, Robling AG, Ferguson VL, Bellido TM, Boerckel JD. “YAP and TAZ mediate osteocyte perilacunar/canalicular remodeling.” Oral presentation at the Orthopaedic Research Society Annual Meeting. Austin, TX, February 2-5, 2019
Kegelman CD, Vigil GD, Horan DJ, Howard SS, Robling AG, Bellido TM, Boerckel JD. “Covariate decoupling of intrinsic and extrinsic bone mechanical properties to reveal progenitor cell function.” Oral presentation at the World Congress of Biomechanics. Dublin, Ireland, July 8-12, 2018.
Kegelman CD, Pearson HB, Dawahare JH, Boerckel JD. “Osteoprogenitor YAP and TAZ promote endochondral fracture repair.” Oral presentation at the World Congress of Biomechanics. Dublin, Ireland, July 8-12, 2018.
Kegelman CD, Collins JM, Mason DE, Boerckel JD. “Osteoprogenitor YAP and TAZ promote Bone Fracture Repair.” Poster presentation at the Orthopaedic Research Society Annual Meeting. New Orleans, LA, March 10-13, 2018.
Kegelman CD, Mason DE, Bellido TM, Robling AG, Boerckel JD. “DMP1-conditional ablation of YAP/TAZ impairs bone matrix organization while reducing accrual differentially in load bearing compared to non-load bearing bone.” Poster presentation at the American Society of Bone and Mineral Research Annual Meeting. Denver, CO, September 8-11, 2017.
Kegelman CD, Dawahare JH, Boerckel JD. “Compensatory Roles of YAP and TAZ in Skeletal Development, Homeostasis, and Repair.” Poster presentation at the Orthopaedic Research Society Annual Meeting. San Diego, CA, March 18-22, 2017.
Kegelman CD, Dawahare JH, Boerckel JD. “Compensatory Roles of Osteoprogenitor YAP and TAZ in Skeletal Development.” Oral presentation at the American Society of Bone and Mineral Research Annual Meeting. Atlanta, GA, September 16-19, 2016.
Awards
2017 - NIH T32- Training in Musculoskeletal Research, University of Pennsylvania
2015 Arthur J. Schmitt Leadership Fellowship in Science and Engineering, University of Notre Dame