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McKay Orthopaedic Research Laboratory

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Boerckel Laboratory

Joe Collins

PhD Candidate, Bioengineering

Hometown: Nashua, New Hampshire

Education

B.S. Mechanical Engineering, University of New Hampshire, 2016

Areas of Interest

Developmental biology, Bone, Mechanotransduction, Progenitor cell behavior.

Publications

  1. McDermott A, Herberg S, Mason D, Pearson H, Dawahare J, Collins J, Grinstaff M, Kelly D, Alsberg E, Boerckel J. (2017) Recapitulating bone development for tissue regeneration through engineered mesenchymal condensations and mechanical cues. Science Translational Medicine. Doi:10.1126/scitranslmed.aav7756
  2. Mason DE, Collins JM, Dawahare, JH, Nguyen TD, Lin Y, Voytik-Harbin SL, Zorlutuna PZ, Yoder ME, Boerckel JD. (2019) YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility. J. Cell Biology. Doi:10.1083/jcb.201806065
  3. Hasseldine B, Gao C, Collins J, Li Y. (2017) Mechanical response of common millet (Panicum miliaceum) seeds under quasi-static compression: Experiments and modeling. J. Mech. Behav. Biomed. Mater. Doi:10.1016/j.jmbbm.2017.01.008
  4. Kegelman, C.D.*, Collins, J.M.*, Nijsure, M.P.*, Eastburn, E.A.*, Boerckel, J.D. (2020) Gone Caving: Roles of the Transcriptional Regulators YAP and TAZ in Skeletal Development. Curr Osteoporos Rep. Doi:10.1007/s11914-020-00605-3. *These authors contributed equally. 

Conference Abstracts and Presentations

External
Oral Presentations
  1. Collins JM, Moharrer Y, Parisi C, Ahmed S, Nowlan NC, Boerckel JD. “YAP and TAZ mediate mechanical regulation of embryonic bone development”. SB3C: summer biomechanics, bioengineering, and biotransport conference 2020. Virtual. June 17-20.
  2. Collins JM, Dyment NA, Boerckel JD. “YAP and TAZ coordinate endochondral ossification”. Orthopaedic Research Society 2020 Annual Meeting. Paper 243. Phoenix, AZ, USA Feb 8-11 2020.
  3. Collins JM, Dyment NA, Boerckel JD. “YAP and TAZ mediate osteoprogenitor mobilization for primary ossification center development”. Biomedical Engineering Society 2019 Annual Meeting. Philadelphia, PA, USA October 16-19, 2019.
  4. Collins JM, Dyment NA, Boerckel JD. “YAP and TAZ mediate osteoprogenitor mobilization for primary ossification center development”. Society for Engineering Science 2019 Annual Meeting. St. Louis, MO, USA October 13-15, 2019. 
  5. Collins JM, Dyment NA, Boerckel JD. “YAP and TAZ coordinate endochondral ossification”. 2019 National Mechanobiology Symposium. St. Louis, MO, USA October 12, 2019. 
  6. Collins JM, Dyment NA, Boerckel JD. “YAP and TAZ mediate osteoprogenitor mobilization for primary ossification center development”. 2019 Annual Meeting of the American Society for Bone and Mineral Research, Abstract 1063. Orlando, FL, USA Sept 20-23, 2019. Young Investigator Award.
  7. Collins JM, Jiang X, Tsinman T, Dyment NA, Boerckel JD. “YAP and TAZ regulate the formation of the primary ossification center in embryonic limbs”. 2019 Annual Meeting of the Orthopaedic Research Society, Paper 0205. Spotlight Session 36. Austin, TX, USA February 2-5, 2019.
  8. Kegelman CD, Pearson HB, Collins JM, Dawahare JH, Jiang X, Dyment NA, Boerckel JD. Osteoprogenitor YAP and TAZ combinatorially promote endochondral fracture repair. 2018 World Congress of Biomechancs. Dublin, Ireland, July 8-12, 2018
Poster Presentations
  1. Jones C, Collins JM, Kim JH, Dyment NA, Boerckel JD. “Quantitative spatial mapping of osteoblast lineage progression in embryonic development.” Orthopaedic Research Society 2020 Annual Meeting. Poster 825. Phoenix, AZ, USA Feb 8-11, 2020. 
  2. Jones C, Collins JM, Dyment NA, Boerckel JD. “Quantitative spatial mapping of osteoblast lineage progression in embryonic development.” Biomedical Engineering Society 2019 Annual Meeting. Philadelphia, PA, USA October 16-19, 2019.
  3. Collins JM, Dyment NA, JD Boerckel. “YAP and TAZ coordinate endochondral ossification” European Calcified Tissue Society PhD Training Course. Bologna, Italy. Sept 7-10, 2019
  4. Kegelman CD, Collins JM, Mason DE, Boerckel JD. Osteoprogenitor YAP and TAZ Promote Fracture Repair. 2018 Annual Meeting of the Orthopaedic Research Society, Poster 1531. New Orleans, LA, March 10-13, 2018.
Internal
Oral Presentations
  1. “YAP and TAZ regulate the formation of the primary ossification center in embryonic limbs”. Orthopaedic Research Day Symposium. June 10, 2019. University of Pennsylvania, Philadelphia, PA.  
  2. “YAP and TAZ regulate the formation of the primary ossification center in embryonic limbs”. McKay Young Investigator Seminar Series. April 23, 2019. University of Pennsylvania, Philadelphia, PA.  
  3.  “YAP and TAZ regulate the formation of the primary ossification center in embryonic limbs”. McKay Graduate Student Seminar. February 13, 2019. University of Pennsylvania, Philadelphia, PA.  
Poster Presentations
  1. Collins JM, Dyment NA, JD Boerckel. “YAP and TAZ coordinate endochondral ossification”. 2019 Penn Center for Musculoskeletal Disorders Symposium, Poster 25. Philadelphia, PA. November 7, 2019.
  2. Collins JM, Jiang X, Tsinman T, Dyment NA, Boerckel JD. “YAP and TAZ regulate the formation of the primary ossification center in embryonic limbs”. 2018 Penn Center for Musculoskeletal Disorders Symposium, Poster 20. Philadelphia, PA. November 7, 2018. 

Awards

  1. 2020 SB3C PhD student paper competition – 2nd place (& finalist)
  2. 2019 Best Poster Award, 2019 Penn Center for Musculoskeletal Disorders Symposium
  3. 2019 ASBMR Annual Meeting Young Investigator Award
  4. 2019 ASBMR Young Investigator Award to attend the European Calcified Tissue Society (ECTS) PhD              Training Course
  5. 2018 Best Poster Award, 2018 Penn Center for Musculoskeletal Disorders Symposium
  6. 2016 Richard and Peggy Notebaert Fellow, University of Notre Dame
  7. 2015 Barry Goldwater Scholar, National
  8. 2015 Churchill Scholarship Nominee, University of New Hampshire
  9. 2013 Mechanical Engineering Scholar, University of New Hampshire
  10. 2012 Hamel Scholar, University of New Hampshire

 

Joe joined the McKay Orthopaedic Research Laboratory in the summer of 2017 and is working on completing his graduate work in the Department of Bioengineering.

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