Keerthana Srinivasan Iyer
Ph. D student
University of Pennsylvania
Hometown
Thane, India
Education
M.S. (Biomedical Engineering) Georgia Institute of Technology, 2022
B.Tech (Biomedical Engineering) Vellore Institute of Technology, 2020
Areas of Special Interest
Pathogenesis and Treatment of Spine Disease
Regeneration of Intervertebral Disc using drug delivery modalities
Immunoregeneration using mesenchymal cells
Publications
1. Lau, Y. K., Iyer, K., Shetye, S., Friday, C. S., Dodge, G. R., Hast, M. W., ... & Smith, L. J. (2024). Evaluation of tendon and ligament microstructure and mechanical properties in a canine model of mucopolysaccharidosis I. Journal of Orthopaedic Research®, 42(7), 1409-1419.
2. Iyer, K., Fazelinia, H., Spruce, L. A., Deng, C., Wang, M., Nesom, G., ... & Smith, L. J. (2026). Comparative proteomic analysis of saliva, urine, and serum in mucopolysaccharidosis type I patients. Molecular Genetics and Metabolism, 147(2), 109479.
3. Rajagopal, K., Iyer, K., Zhang, D., Molony, C. M., Casal, M. L., & Smith, L. J. (2026). In vitro evaluation of therapeutic beta-glucuronidase enzyme uptake and penetration in articular cartilage. Molecular Genetics and Metabolism, 147(2), 109590.
4. Maparu, A. K., Iyer, K., Rajagopal, K., Siddiqui, Z., Campbell, R., Molony, C. M., ... & Smith, L. J. (2025, February). Porous microcarriers for sustained delivery of mRNA-lipid nanoparticles to treat joint disease in the mucopolysaccharidoses. In Molecular Genetics and Metabolism (Vol. 144, No. 2). 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA: ACADEMIC PRESS INC ELSEVIER SCIENCE.
5. Rajagopal, K., Swingle, K. L., Iyer, K., Jiang, Z., Smith, E., Molony, C., ... & Smith, L. J. (2025, February). In vitro development and in vivo evaluation of intra-articular GUSB mRNA therapy for mucopolysaccharidosis type VII. In Molecular Genetics and Metabolism (Vol. 144, No. 2). 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA: ACADEMIC PRESS INC ELSEVIER SCIENCE.