Se-Hwan Lee, Ph.D.
University of Pennsylvania
Seoul, South Korea
Ph.D. Mechanical Engineering, Wonkwang University 2018
M.S. Mechanical Engineering, Wonkwang University 2012
B.S. Mechanical Engineering, Wonkwang University 2010
Areas of Special Interest
I’ve researched customized 3D printing based multifunctional scaffolds including numerical analysis-based design, medical image-based reconstruction, hierarchical pore structure, drug delivery, and light active dECM bioink. It is focusing on the development of artificial soft tissue with zonal dependent maturation by multi 3D patterning. Outside the lab., I like to enjoy futsal, table tennis, running, biking, and hiking.
Se-Hwan Lee, Hyoryung Nam, Bosu Jeong, Jinah Jang: Chapter 8. 3D Printing and Bioprinting Technologies, Hyun Jung Kim (Ed.). CRC press, Jan 2020 Notes: Book Chapter.
Se-Hwan Lee*, Kang-Gon Lee*, Jaeyeon Lee, Yong Sang Cho, Min-Soo Ghim, Soojin Kim, Su-Jin Heo, Yongdoo Park, Young-Sam Cho and Bu-Kyu Lee: Three dimensional kagome structures in a PCL/HA-based hydrogel scaffold to lead slow BMP-2 release for effective bone regeneration. Bio-Design and Manufacturing: Accepted, 2022 Notes: *: Equal contributions as first author.
Seung Hyeon Hwang*, Jongbeom Kim*, Chaejeong Heo, Hyeonji Kim, Se-Hwan Lee, Hyung Woo Park, Man Seung Heo, Hyo Eun Moon, Chulhong Kim, Sun Ha Paek, and Jinah Jang: 3D Printed Multi-Growth Factors Delivery Patches with Decellularized Extracellular Matrix-Based Hybrid Inks Via Aza-Michael Addition for Promoting Cerebral Angiogenesis. Acta Biomaterialia: Accepted, 2022 Notes: *: Equal contributions as first author
Hyoryung Nam, Yoo-mi Choi, Sungkeon Cho, Ge Gao, Donghwan Kim, Jongmin Kim, Hwanyong Choi, Se-Hwan Lee and Jinah Jang: Modular assembly of bioprinted perfusable blood vessel and tracheal epithelium for studying inflammatory respiratory diseases. Biofabrication: Accepted, 2022
Hyeonji Kim*, Byeongmin Kang*, Xiaolin Cui*, Se-Hwan Lee, Kwangseok Lee, Dong-Woo Cho, Woonbong Hwang, Tim B. F. Woodfield, Khoon S. Lim, Jinah Jang: Light-activated decellularized extracellular matrix-based bioinks for volumetric tissue analogs at the centimeter scale. Advanced Functional Materials 31(32): 2011252, May 2021 Notes: *: Equal contributions as first author (Cover figure).
Seunggyu Jeon*, Se-Hwan Lee*, Saeed B. Ahmed, Jonghyeuk Han, Su-Jin Heo, Hyun-Wook Kang: 3D cell aggregate printing technology and its applications. Essays in Biochemistry 65(3): 467-480, Aug 2021 Notes: *: Equal contributions as first author.
Byeong Gon Yun*, Se-Hwan Lee*, Jung Ho Jeon, Seok-Won Kim, Chan Kwon Jung, Gyeongsin Park, Su Young Kim, Sora Jeon, Min Suk Lee, Sun Hwa Park, Jinah Jang, Hee Seok Yang, Dong-Woo Cho, Jung Yeon Lim, Sung Won Kim: Accelerated bone regeneration via three-dimensional cell-printed constructs containing human nasal turbinate-derived stem cells as a clinically applicable therapy. ACS Biomaterials Science & Engineering 5: 6171-6185, Oct 2019 Notes: *: Equal contributions as first author.
Yong Sang Cho*, Meiling Quan*, Se-Hwan Lee, Myoung Wha Hong, Young Yul Kim, Young-Sam Cho: Assessment of osteogenesis for 3D-printed polycaprolactone/hydroxyapatite composite scaffold with enhanced exposure of hydroxyapatite using rat calvarial defect model. Composites Science and Technology 184: 1077844, Nov 2019 Notes: *: Equal contributions as first author.
Sanskrita Das*, Seok-Won Kim*, Yeong-Jin Choi, Sooyeon Lee, Se-Hwan Lee, Jeong-Sik Kong, Hun-Jun Park, Dong-Woo Cho, Jinah Jang: Decellularized extracellular matrix bioinks and the external stimuli to enhance cardiac tissue development in vitro. Acta Biomaterialia 95: 188-200, Sept 2019 Notes: *: Equal contributions as first authors.
Yong Sang Cho, Sunkyung Choi, Se-Hwan Lee, Kee K. Kim, Young-Sam Cho: Assessments of polycaprolactone/hydroxyapatite composite scaffold with enhanced biomimetic mineralization by exposure to hydroxyapatite via a 3D-printing system and alkaline erosion. European Polymer Journal 113: 340-348, April 2019
Se-Hwan Lee*, Kang-Gon Lee*, Jong-Hyun Hwang, Yong Sang Cho, Kang-Sik Lee, Hun-Jin Jeong, Sang-Hyug Park, Yongdoo Park, Young-Sam Cho, Bu-Kyu Lee: Evaluation of mechanical strength and bone regeneration ability of 3D printed kagome-structure scaffold using rabbit calvarial defect model. Materials Science and Engineering C 98: 949-959, May 2019 Notes: *: Equal contributions as first authors.
Jaeyeon Lee, Se-Hwan Lee, Byung Soo Kim, Young-Sam Cho, Yongdoo Park: Development and evaluation of hyaluronic acid-based hybrid bio-ink for tissue regeneration. Tissue Engineering and Regenerative Medicine 15(6): 761-769, Sept 2018
Jaeyeon Lee*, Se-Hwan Lee*, Bu-Kyu Lee, Sang-Hyug Park, Young-Sam Cho, Yongdoo Park: Fabrication of microchannels and evaluation of guided vascularization in biomimetic hydrogels. Tissue Engineering and Regenerative Medicine 15(4): 403-413, 2018 Notes: *: Equal contributions as first authors.
Yong Sang Cho, Joon Sup Lee, Myoung Wha Hong, Se-Hwan Lee, Young Yul Kim, Young-Sam Cho: Comparative assessment of the ability of dual-pore structure and hydroxyapatite to enhance the proliferation of osteoblast-like cells in well-interconnected scaffolds. International Journal of Precision Engineering and Manufacturing 19(4): 605-612, April 2018
Kang-Gon Lee*, Kang-Sik Lee*, Yu-Jeoung Kang, Jong-Hyun Hwang, Se-Hwan Lee, Sang-Hyug Park, Yongdoo Park, Young-Sam Cho, Bu-Kyu Lee: Rabbit calvarial defect model for customized 3D-prinited bone grafts. Tissue Engineering Part C Methods 24(5): 255-262, May 2018 Notes: *: Equal contributions as first authors.
Se-Hwan Lee, Yong Sang Cho, Myoung Wha Hong, Bu-Kyu Lee, Yongdoo Park, Sang-Hyug Park, Young Yul Kim, Young-Sam Cho: Mechanical properties and cell-culture characteristics of a polycaprolactone kagome-structure scaffold fabricated by a precision extruding deposition system. Biomedical Materials 12(5): 055003, Sept 2017
Yong Sang Cho, Myoung Wha Hong, Meiling Quan, So-Youn Kim, Se-Hwan Lee, Seung-Jae Lee, Young Yul Kim, Young-Sam Cho: Assessments for bone regeneration using the polycaprolactone SLUP (salt-leaching using powder) scaffold. Journal of Biomedical Materials Research Part A 105(12): 3432-3444, Sept 2017
Beom-Su Kim, Sun-Sik Yang, Ho Park, Se-Hwan Lee, Young-Sam Cho, Jun Lee: Improvement of mechanical strength and osteogenic potential of calcium sulfate-based hydroxyapatite 3-dimensional printed scaffolds by ε-polycarbonate coating. Journal of Biomaterials Science-Polymer Edition 28(13): 1256-1270, Jun 2017
Se-Hwan Lee, Jun Hee Lee, Young-Sam Cho: Analysis of degradation rate for dimensionless surface area of well-interconnected PCL scaffold via in-vitro accelerated degradation experiment. Tissue Engineering and Regenerative Medicine 11(6): 446-452, Nov 2014
Se-Hwan Lee, A Ra Jo, Ghi Pyoung Choi, Chang Hee Woo, Seung Jae Lee, Beom-Su Kim, Hyung-Keun You, Young-Sam Cho: Fabrication of 3D alginate scaffold with interconnected pores using wire-network molding technique. Tissue Engineering and Regenerative Medicine 10(2): 53-59, April 2013 (Cover figure).
Young-Sam Cho#, Sang Hyun Ahn, Se-Hwan Lee: Fabrication and analysis of PMMA, ABS, PS, and PC superhydrophobic surfaces using the spray method. Journal of the Korean Physical Society 63(2): 218-224, Aug 2013 Notes: #: Corresponding author.
Ghi Pyoung Choi, Dongwoo Sohn, Chang Hee Woo, Se-Hwan Lee, Sang Hyun Ahn, Young-Sam Cho: Qualitative verification of the dispersion level in nano-composite and its application to YD-128/MWCNT composite to assess the wear characteristics with respect to the dispersion level. Journal of Mechanical Science and Technology 27(10): 3131-3138, Oct 2013
Chang Hee Woo, Tae Young Kim, Se-Hwan Lee, Ghi Pyoung Choi, Seung Jae Lee, Beom-Su Kim, Hyung-Keun You, Young-Sam Cho: Development of a novel technique for scaffold fabrication and its characterizations: wire-network molding (WNM) technique. Tissue Engineering and Regenerative Medicine 9: 65-72, Jan 2012
Honors and Awards
2014 Academic scholarship of graduate school, Wonkwang University, South Korea
2012 Best presentation award (Poster presentation), the Korean Society of Mechanical Engineers, South Korea