Yuna Heo
Ph.D. Student in Bioengineering
University of Pennsylvania
Hometown
Buffalo, New York
Education
B.S. Biomedical Engineering, University at Buffalo, 2022
Areas of Special Interest
Biophysical cues with chromatin organization and gene expression in tenocytes; vascular extracellular matrix mechanobiology, survivin in vascular smooth muscle cell-mediated neointima formation and arterial stiffening. During my free time, I enjoy listening to music, watching movies and shows, going on walks, and spending time outdoors.
Publications
Biber JC, Sullivan A, Brazzo III J, Heo Y, Tumenbayar B, Krajnik A, Poppenberg K, Tutino VM, Heo S, Kolega J, Lee K, Bae Y. (2023) Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells. APL Bioengineering (Dec), 7(4) doi: 10.1063/5.0150532
Krajnik A, Nimmer E, Brazzo JA, Biber JC, Drewes R, Tumenbayar BI, Sullivan A, Pham K, Krug A, Heo Y, Kolega J, Heo SJ, Lee K, Weil BR, Kim DH, Gupte SA, Bae Y. (2023) Survivin regulates intracellular stiffness and extracellular matrix production in vascular smooth muscle cells. APL bioengineering (Dec), 7(4): 046104. doi: 10.1063/5.0157549
Szigeti K, Ihnatovych I, Rosas N, Dorn RP, Notari E, Cortes Gomez E, He M, Maly I, Prasad S, Nimmer E, Heo Y, Fuchsova B, Bennett DA, Hofmann WA, Pralle A, Bae Y, Wang J. (2023) Neuronal actin cytoskeleton gain of function in the human brain. EBioMedicine (Sep), 95: 104725. doi: 10.1016/j.ebiom.2023.104725
Brazzo JA, Biber JC, Nimmer E, Heo Y, Ying L, Zhao R, Lee K, Krause M, Bae Y. (2021) Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation. Journal of cell science (Jun), 134(12). doi: 10.1242/jcs.257709
Conference Abstracts
Heo Y, Zhang Y, Bae Y, Heo S. “Dynamic tensile loading modulates gene expression through epigenetic regulation in tenocytes” 2024 Biomedical Engineering Society Annual Meeting. Baltimore, MD (Podium Presentation)
Heo Y, Lee S, Drewes R, Thomas C, Pham K, Bae Y, Heo S. “A stiffness-tunable ECM-based vascular model reveals survivin/YAP-medicated mechanotransduction in human VSMCs” 2024 Biomedical Engineering Society Annual Meeting. Baltimore, MD (Poster Presentation)
Heo Y, Zhang Y, Bae Y, Heo S. “Deciphering epigenetic responses in tenocytes to long-term dynamic tensile loading: implications for tendon degeneration mechanisms” 2024 Orthopaedic Research Society Annual Meeting. Long Beach, CA (Poster Presentation)
Rice K, Mousso T, Tumenbayar B, Heo Y, Bae Y. “Survivin orchestrates stiffness-induced vascular smooth muscle cell migration” 2023 American Society of Cell Biology and European Molecular Biology Organization Meeting. Boston, MA (Poster Presentation)
Krajnik A, Nimmer E, Sullivan A, Brazzo III JA, Heo Y, Krug A, Kolega J, Heo S, Lee K, Weil BR, Kim D, Bae Y. “Survivin regulates intracellular stiffness and extracellular matrix production in vascular smooth muscle cells” 2023 Biophysical Society Annual Meeting. San Diego, California (Poster Presentation)
Brazzo III JA, Heo Y, Bae Y. “Lamellipodin drives stiffness-dependent cell cycling through YAP” 2022 American Society of Cell Biology and European Molecular Biology Organization Meeting. Washington, D.C. (Poster Presentation)
Brazzo III JA, Biber JC, Nimmer E, Heo Y, Lee K, Krause M, Bae Y. “Role of lamellipodin in cellular mechanotransduction” 2021 American Society for Matrix Biology Biennial Meeting. St. Louis, MO (Podium Presentation)