Smith/Malhotra Laboratory

Zhirui Jiang, Ph.D.

Zhirui Jiang, Ph.D.

Postdoctoral Researcher
University of Pennsylvania

Hometown

Qingdao, China

Education

Ph.D. (Bioscience), The University of Adelaide, Australia

B.Sc. (Genetics Honours), The University of Adelaide, Australia

B.Sc. (Biotechnology), The University of Adelaide, Australia   

Areas of Special Interest

  • Mechanism of failed endochondral bone formation in Mucopolysaccharidosis
  • Therapeutic approaches for spine disease in Mucopolysaccharidosis

Publications

Jiang Z, Derrick-Roberts ALK, Rossouw C, Jackson MR, Pyragius CE, Byers S. Delayed development of ossification centers in the tibia of prenatal and early postnatal MPS VII mice, Molecular Genetics and Metabolism, 2018 Jun;124(2):135-142. doi:10.1016/j.ymgme.2018.04.014. Epub 2018 May 3.

Awards

Feb 2018, WORLDSymposium, Young Investigator Award

Mar 2016, WORLDSymposium, Young Investigator Award

Abstracts

Jiang Z, Rossouw C, Reichstein C, Macsai CE, Jackson MR, Derrick-Roberts ALK, & Byers S. MPS VII mice display reduced circulating IGF1 and disrupted cell cycle progression in the growth plate, Mol Genet Metab (2018), vol.123, no.2.

Jiang Z, Rossouw C, Reichstein C, Macsai CE, Jackson MR, Derrick-Roberts ALK, Byers S. Reduced chondrocyte proliferation and hypertrophy contribute to delayed endochondral bone formation in murine Mucopolysaccharidosis VII, Mol Genet Metab (2016), vol.117, no.2,pp. S62-S63.

Byers S, Jiang Z, Reichstein C, Derrick-Roberts ALK. Cell cycle progression is disrupted in murine MPS VII growth plate chondrocytes, Molecular Genetics and Metabolism, Volume 120, Issues 1–2, January–February 2017, Page S33, ISSN 1096-7192.

Jiang Z, Derrick-Roberts ALK, Byers S. Mucopolysaccharidosis VII mice have reduced circulating IGF1 level and disrupted cell cycle progression in the growth plate. Australia and New Zealand Orthopaedic Research Society (2017), Adelaide, Australia.

Jiang Z, Reichstein C, Rossouw C, Derrick-Roberts ALK, Byers S. Disrupted cell cycle progression in growth plate chondrocytes contributes to reduced bone growth in Mucopolysaccharidoses VII. Bone and cartilage: from development to human disease. Cold Harbor Spring Asia (2016), Suzhou, China.

Jiang Z, Reichestein C, Derrick-Roberts ALK, Byers S. Decreased number of proliferating chondrocytes and delayed hypertrophy in Mucopolysaccharidosis VII growth plate. Australia and New Zealand Orthopaedic Research Society (2014), Adelaide, Australia.

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