Meet a PennMedicine Researcher
Katherine L. Nathanson, MD
Katherine L. Nathanson, MD, Professor of Medicine and Deputy Director of the Abramson Cancer Center, is the winner of this year’s William Osler Patient Oriented Research Award, which is granted to a member of the PSOM faculty for a body of work with an emphasis on clinical research.
Dr. Nathanson leads an internationally recognized research program which focuses on basic discovery of germline and somatic genetic variation leading to cancer, and the translation of cancer genetics research into improved clinical care for patients. She has emerged as an international leader in the genetics of several different cancer types, including testicular cancer, melanoma, renal and adrenal cancers, and hereditary breast and ovarian cancers. Dr. Nathanson is the foremost expert in the field of inherited susceptibility to Testicular Germ Cell Tumors (TGCT). Her research in the area of the genetic basis of hereditary breast and ovarian cancer has had a profound impact on those who suffer from these diseases, as it has greatly increased our understanding of the heterogeneity of and identified genetic causes of familial breast cancer. She has used genetic/genomic information to directly impact and improve therapeutic outcomes in melanoma. Finally, she has made essential contributions to our understanding of the somatic and inherited genetics of pheochromocytoma/paragangliomas (PCC/PGL). As one colleague noted: “Dr. Nathanson enriches the entire scientific enterprise of the Perelman School of Medicine patient oriented research community in ways that few other physician-scientists do.”