Principal Investigator

Eddie Lee, M.D., Ph.D.Edward Lee Headshot

“After completing my undergrad degree at Stanford University, I received my medical degree and doctoral degree in Neuroscience from Penn, followed by clinical training in Anatomic Pathology and Neuropathology from HUP.  I am currently Associate Professor in the Department of Pathology and Laboratory Medicine, Co-Director of the Penn Institute on Aging, and Associate Director of the Penn Alzheimer's Disease Research Center.  I am also a practicing neuropathologist in the illustrious Division of Neuropathology.


My research involves using of advanced molecular, biochemical and histologic techniques to analyze brain tissue in study the molecular pathways associated with neuropathologic inclusions in frontotemporal lobar degeneration, amyotrophic lateral sclerosis, Alzheimer's disease, and Trauma-Related Neurodegeneration.  I am the leader of the neuropathology cores of the Penn ADRC, the Penn FTDC, the Penn U19 Center on alpha-synuclein strains in ADRD,  and the multi-institutional, international CONNECT-TBI consortium.


My goals include maintaining a world-class experimental neuropathology laboratory and supporting lab members in our collective mission to increase our understanding of the causes and cures of aging-related neurodegenerative diseases.”