Ravi Prakash Reddy Nanga, Ph.D, R.Ph
Research Assistant Professor of Radiology
Contact Information
422 Curie Blvd
B1 Stellar-Chance Laboratories
Philadelphia, PA 19104
Fax: 215-573-2113
Lab: 215-898-2045
Email: nravi@pennmedicine.upenn.edu
Education:
BS (Pharmacy) Kakatiya University, 2001
MS (Chemistry) University Of Michigan, 2010
PhD (Chemistry) University Of Michigan, 2011
Description of Research Expertise
My research interest consists of acquisition and quantification strategies focused on the study of brain metabolites in vivo in humans (in disease state such as Epilepsy, Schizophrenia and in acute drug studies) by MR spectroscopy and CEST MRI. I have been the lead MR scientist for several clinical research projects involving the spectroscopic and CEST acquisitions as well as analysis of the data acquired from 7T Siemens MRI scanner. I would like to use the experience I have gained over the years on these newly developed MRI contrast techniques along with MR spectroscopy to study the metabolism and to capture the early detection and therapeutic monitoring of neurodegenerative diseases/neurological disorders.
Selected Publications
Guruprasad Krishnamoorthy, Ravi Prakash Reddy Nanga, Puneet Bagga, Hari Hariharan, Ravinder Reddy: High quality three-dimensional gagCEST imaging of in vivo human knee cartilage at 7 Tesla. Magnetic Resonance in Medicine 77(5): 1866-1873, May 2017.
DeBrosse Catherine*, Nanga Ravi Prakash Reddy*, Bagga Puneet, Nath Kavindra, Haris Mohammed, Marincola Francesco, Schnall Mitchell D, Hariharan Hari, Reddy Ravinder (*Equal contribution): Lactate Chemical Exchange Saturation Transfer (LATEST) Imaging in vivo: A Biomarker for LDH Activity. Scientific Reports. Nature Publishing Group, 6: 19517, January 2016.
Davis Kathryn Adamiak*, Nanga Ravi Prakash Reddy*, Das Sandhitsu, Chen Stephanie H, Hadar Peter N, Pollard John R, Lucas Timothy H, Shinohara Russell T, Litt Brian, Hariharan Hari, Elliott Mark A, Detre John A, Reddy Ravinder (*Equal contribution): Glutamate imaging (GluCEST) lateralizes epileptic foci in nonlesional temporal lobe epilepsy. Science translational medicine 7(309): 309ra161, Oct 2015.
Catherine DeBrosse, Ravi Prakash Reddy Nanga, Neil Wilson, Kevin D'Aquilla, Mark Elliott, Feliks Kogan, Hari Hariharan, Felicia Yan, Leat Perez, Sara Nguyen, Elizabeth McCormick, Marni Falk, Ravinder Reddy, Shana McCormack: In vivo oxphos quantitation by magnetic resonance imaging in metabolic myopathy. MOLECULAR GENETICS AND METABOLISM. ACADEMIC PRESS INC ELSEVIER SCIENCE, 114(3): 313-314, 2015.
Verma Gaurav, Hariharan Hari, Nagarajan Rajakumar, Nanga Ravi Prakash Reddy, Delikatny Edward J, Albert Thomas M, Poptani Harish: Implementation of two-dimensional L-COSY at 7 Tesla: an investigation of reproducibility in human brain. Journal of magnetic resonance imaging : JMRI 40(6): 1319-27, Dec 2014.
Crescenzi Rachelle, DeBrosse Catherine, Nanga Ravi Prakash Reddy, Reddy Sanjana, Haris Mohammed, Hariharan Hari, Iba Michiyo, Lee Virginia M Y, Detre John A, Borthakur Arijitt, Reddy Ravinder: In vivo measurement of glutamate loss is associated with synapse loss in a mouse model of tauopathy. NeuroImage 101: 185-92, Nov 2014.
Kogan Feliks, Haris Mohammad, Debrosse Catherine, Singh Anup, Nanga Ravi Prakash Reddy, Cai Kejia, Hariharan Hari, Reddy Ravinder: In vivo chemical exchange saturation transfer imaging of creatine (CrCEST) in skeletal muscle at 3T. Journal of magnetic resonance imaging : JMRI 40(3): 596-602, Sep 2014.
Nanga Ravi Prakash Reddy, DeBrosse Catherine, Singh Anup, D'Aquilla Kevin, Hariharan Hari, Reddy Ravinder: Glutaminase catalyzes reaction of glutamate to GABA. Biochemical and biophysical research communications 448(4): 361-4, Jun 2014.
Kogan Feliks, Haris Mohammad, Singh Anup, Cai Kejia, Debrosse Catherine, Nanga Ravi Prakash Reddy, Hariharan Hari, Reddy Ravinder: Method for high-resolution imaging of creatine in vivo using chemical exchange saturation transfer. Magnetic resonance in medicine 71(1): 164-72, Jan 2014.
C Neill Epperson, Ravi Prakash Reddy Nanga, Kosha Ruparel, Simon Vandekar, Sheila Shanmugan, Sarah Conlin, Ravinder Reddy, Ruben Gur: Psychostimulant and Estrogen Effects on Prefrontal Cortex Function During Menopause: Are There Effects of Early Life Adversity? BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC, 75(9): 279S-279S, 2014.