Mauck Laboratory

Elisabeth Lemmon

Graduate Student in Bioengineering

University of Pennsylvania 

Hometown: 

Columbia, MD 

Education: 

V.M.D. Candidate, University of Pennsylvania School of Veterinary Medicine 

B.S., University of Delaware, 2018 

Areas of Special Interest: 

developmental biology, extracellular matrix, stem cell biology, translational therapies, musculoskeletal injury and healing 

In my spare time: 

running, hiking, and spending time with my beagle, Boh!

Publications: 

Lemmon EA, Bonnevie ED, Patel JM, Miller LM, Mauck RL. Transient Inhibition of Meniscus Cell Migration Following Acute Inflammatory Challenge. J Orthop Res. 2023 Sep;41(9):2055-2064. doi: 10.1002/jor.25545. Epub 2023 Mar 22. PMID: 36866823.

Bansal S, Meadows KD, Miller LM, Saleh KS, Patel JM, Stoeckl BD, Lemmon EA, Hast MW, Zgonis MH, Scanzello CR, Elliott DM, Mauck RL. Six-month Outcomes of Clinically Relevant Meniscal Injury in a Large-Animal Model. Orthop J Sports Med. 2021 Nov 12;9(11):23259671211035444. doi: 10.1177/23259671211035444. PMID: 34796238; PMCID: PMC8593308.

Locke RC, Lemmon EA, Dudzinski E, Kopa SC, Wayne JM, Soulas JM, De Taboada L, Killian ML. Photobiomodulation Does not Influence Maturation and Mildly Improves Functional Healing of Mouse Achilles Tendons. J Orthop Res. 2020 Aug;38(8):1866-1875. doi: 10.1002/jor.24592. Epub 2020 Jan 28. PMID: 31965620; PMCID: PMC8637462.

Lemmon EA, Locke RC, Szostek AK, Ganji E, Killian ML. Partial-Width Injuries of the Rat Rotator Cuff Heal with Fibrosis. Connect Tissue Res. 2018 Sep;59(5):437-446. doi: 10.1080/03008207.2018.1485666. Epub 2018 Jul 2. PMID: 29874950; PMCID: PMC6324170.

Locke RC, Peloquin JM, Lemmon EA, Szostek A, Elliott DM, Killian ML. Strain Distribution of Intact Rat Rotator Cuff Tendon-to-Bone Attachments and Attachments With Defects. J Biomech Eng. 2017 Nov 1;139(11):1110071–6. doi: 10.1115/1.4038111. PMID: 28979985; PMCID: PMC5676647.

 

Abstracts:

Kupratis M, Zhang Y, Xiang J, Kwok B, Lemmon EA, Dyment N, Han L, Koyama E, Mauck RL. Micromechanics and mechanoresponsivity of the developing porcine meniscus. Biomechanics, Bioengineering, and Biotransport. Lake Geneva, WI, June, 2024. Abstract Author.

Zhang Y, Kwok B, Xu K, Kupratis M, Lemmon EA, Dyment N, Han L, Koyama E, Mauck RL. Morphogenesis and Mechano-Response of the Developing Porcine Meniscus. Orthopaedic Research Society. Long Beach, CA, February, 2024. Abstract Author.

Baghdadi S, Stoeckl BD, Lemmon EA, Nguyen JC, Dehghani B, Patel V, Yaya C, Mauck RL, Ganley T. Healing of Partial-Thickness Cartilage Injuries in the Immature Skeleton: Development of a Large Animal Model for Pediatric Cartilage Research. Pediatric Orthopaedic Society of North America. National Harbor, MD, May, 2024. Abstract Author.

Lemmon EA, Dehghani B, Kwok B, Han L, Mauck RL. A Small Molecule TGF-B Agonist Drives Fibrous Tissue Formation in Meniscus Tissue after Injury. Orthopaedic Research Society. Long Beach, CA, February, 2024. Poster Presentation

Lemmon EA, Kim SY, Kwok B, Laforest L, Hallström G, Burt KG, Han L, Scanzello CR, Mauck RL, Agnello KA. Interleukin Receptor Therapeutics Attenuate Synovial Inflammation in Canines following Cruciate Ligament Injury. Orthopaedic Research Society. Long Beach, CA, February, 2024. Podium Presentation

Stoeckl BD, Masada KM, Moore AC, Fogarty NL, Lemmon EA, Dehghani B, Laforest L, Carey JL, Steinberg DR, Stevens MM, Mauck RL. Osteochondral Defect Repair of Large Weight-Bearing Surfaces in a Porcine ModelOrthopaedic Research Society. Long Beach, CA, February, 2024. Abstract Author.

Jenk AC, Scweppe EA,  Lemmon EA, Gullbrand SE,  Mauck RL. Hyaluronic Acid Carrier Prolongs the Lifespan of Therapeutically Loaded Microcapsules. Orthopaedic Research Society. Long Beach, CA, February, 2024. Abstract Author.

AC Jenk, Scweppe EA,  Lemmon EA, Gullbrand SE,  Mauck RL. Hyaluronic Acid Stabilizes Therapeutic Mechanically-Activated Microcapsules for Field Deployment. Extremity War Injuries XVII. Washington, DC, January, 2024. Abstract Author.  

Jenk AC, EA Lemmon, SE Gullbrand, Mauck RL. N-Acetyl Cysteine Rescues Chondrocytes from Oxidative Stress and Increases their Metabolic Activity. Biomechanics, Bioengineering, and Biotransport. Vail, Colorado, June, 2023. Abstract Author.

EA Lemmon, Locke RC, Stoeckl BD, Jenk AC, Hast MW, Agnello KA, Mauck RL. Mechanoactive Delivery of Immunosuppressive Therapies to Restore Synovial and Meniscus Cell Function. Veterinary Orthopedic Society. Big Sky, Montana, March, 2023. Podium Presentation.

EA Lemmon, Locke RC, Stoeckl BD, Jenk AC, Hast MW, Mauck RL. Mechanoactive Anti-Inflammatory Drug Delivery to Meniscus Defects. Orthopaedic Research Society. Dallas, TX, February, 2023. Poster Presentation.

EA Lemmon, Burt KG, Bernstein E, Sharp EE, Stoeckl BD, Laforest L, Scanzello CR, Mauck RL, Agnello KA. Anakinra Reduces Inflammatory Pathways Activated in Canine Synovium after Cranial Cruciate Ligament Injury. Orthopaedic Research Society. Dallas, TX, February, 2023. Poster Presentation.

Bernstein E, EA Lemmon, Jenk AC, Mauck RL. IL-1Ra Delivery Restores Phenotype and Preserves Matrix in Inflammatory Meniscus Micro-Tissues. Orthopaedic Research Society. Dallas, TX, February, 2023. Abstract Author.

Zlotnick HM, Azar T…, Lemmon EA…, Gullbrand, S. Reimagining Conferences as a Platform to Provide Early Research Exposure and Networking to Diverse Undergraduates. Orthopaedic Research Society. Tampa, FL, February, 2022. Abstract Author

Jones D, Jiang X, Bonnevie ED, Lemmon EA, Evans M…, Mauck RL. Tensional Homeostasis Regulates Chromatin Accessibility and Represses Matrix Degradation Pathways Through TAP/TAZ. Biomechanics, Bioengineering, and Biotransport. Virtual, June, 2021. Abstract Author

Zlotnick HM, Peredo A,…, Lemmon EA…, Mauck, R. Distribution and Biocompatibility of Mechanically-Activated Microcapsules in a Large Animal Model. Biomedical Engineering Society. Orlando, FL, October, 2021. Abstract Author

Patel JM, Loebel, C…, Lemmon, EA, et al. Stabilization of Damaged Cartilage via Hydrogel-Mediated Reinforcement and Sealing. Orthopaedic Research Society. Virtual, February, 2021. Abstract Author.

Lemmon EA, Miller L, Patel JM, Mauck RL. Inflammatory Challenge Alters Cytoskeletal Networks and TransientlyInhibits Meniscus Cell Migration. Orthopaedic Research Society. Phoenix, AZ, February, 2020. Podium Presentation.

Miller L, Heo S, Lemmon EA, Bansal S, Zgonis M, Mauck RL. Translating Improvements in Interstitial Cell Migration viaNuclear Softening for Dense Connective Tissue Repair. Orthopaedic Research Society. Phoenix, AZ, February, 2020. Abstract Author.

Locke RC, Lemmon EA, Killian M. Mitochondrial Genes Are Differentially Expressed in Mouse Achilles Tendons DuringPostnatal Growth and Injury. Orthopaedic Research Society. Phoenix, AZ, February, 2020. Abstract Author.

Locke RC, Lemmon EA, Dudzinski E, Kopa SC, Newman HR, Ganji E, Killian M. Mitochondrial Function and Histomechanical Outcomes after Exposure to Near-Infrared Light during Tendon Maturation and Adult Healing. OrthopaedicResearch Society. Austin, TX, February 2019. Abstract Author.

Lemmon EA, Locke RC, Szostek A, Killian M. Partial-Width Injury of the Tendon-Bone Attachment Leads to Spontaneous Healing and Diminished Structural Quality in the Rat Rotator Cuff. Orthopaedic Research Society. New Orleans, LA, March 2018. Poster Presentation.

Locke RC, Peloquin JM, Lemmon EA, Szostek A, Elliott DM, & Killian M. Localized Strain and Biomechanics of the Disrupted Tendon Bone Attachment. Biomedical Engineering Society. Phoenix, AZ, October 2017. Abstract Author.

Lemmon EA, Locke RC, Szostek A, Killian M. Structural Properties and Composition of the Tendon-Bone Attachment Are Altered Following Acute Partial- Width, Full-Thickness Tendon-Bone Injury in a Rat Rotator Cuff Defect Model. NASA DE Space Grant Research Symposium. Newark, DE, April 2017. Poster Presentation.

Lemmon EA, Locke RC, Szostek A, Killian M. Biomechanical Strength and Stiffness are Impaired Following Acute Partial-Width, Full-Thickness Tendon-Bone Injury in a Rat Rotator Cuff Defect Model. Orthopaedic Research Society. San Diego, CA, March 2017. Poster Presentation.

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