Mauck Laboratory

Ellie Bernstein

Medical Student
University of Pennsylvania

Hometown

Seattle, WA

Education

BA, Harvard University 2020

Areas of Special Interest

Tissue engineering and meniscus repair

Awards

Measey Surgical Scholar (2020-2021), John Harvard Scholar (2019), Mary Gordon Robert Fellow (2019), Mindich Fellow (2018), PRISE Fellow (2017)

Publications

Azari F, Kennedy G, Folkert I, Bou-Samra P, Chang A, Chang A, Bernstein E, Nadeen B, Desphande C, Srinivasarao M, Mukkamala R, Sullivan N, Weber K, Eruslanov E, Albelda SM, Low P & Singhal S. (2022). A fibroblast activation protein targeted optical tracer for identifying primary and metastatic sarcoma during resection. [Submitted for publication].
Kennedy G, Cameron R, Wakeam E, Azari F, Chang A, Nadeem B, Bernstein E, Segil A, Din A, Marfatia I, Desphande C, Okusanya O, Keating J, Predina J, Newton A, Kucharczuk J & Singhal S. [in press]. Single institution experience of 500 pulmonary resections guided by intraoperative molecular imaging. The Journal of Thoracic and Cardiovascular Surgery. 
Azari F, Kennedy G, Chang A, Nadeem B, Bou-Samra P, Chang A, Bernstein E, Sullivan N, Eruslanov E, Delikatny J & Singhal S. [in press]. Sodium multivitamin transporter-targeted fluorochrome facilitates enhances metabolic evaluation of tumors through coenzyme-R dependent intracellular signaling pathways. Molecular Imaging and Biology.
Talwar A, Lanni MA, Ryan IA, Kodali P, Bernstein E, McAuliffe PB, Broach RB, Serletti JM, Butler PD & Fosnot J. [in press]. Prepectoral vs. submuscular implant-based breast reconstruction: A matched-pair comparison of outcomes. Plastic and Reconstructive Surgery.
Kennedy GT, Holt D, Azari F, Bernstein E, Nadeem B, Chang A, Sullivan N, Segil A, Deshpande C, Bensen ES, Santini JT, Kucharczuk J, Delikatny J, Bogyo M, Egan M, Bradley C, Eruslanov EB, Lickliter JD, Wright G & Singhal S. (2022). A cathepsin targeted quenched activity-based probe facilitates enhanced detection of human tumors during resection. Clinical Cancer Research, 28(17), 3729–3741. DOI: 10.1158/1078-0432.CCR-22-1215.
Kennedy GT, Azari FS, Nadeem B, Chang A, Segil A, Bernstein E, Deshpande C, Kucharczuk JC, Delikatny EJ & Singhal S. (2022). Preclinical evaluation of a novel quenched activity-based near-infrared probe for intraoperative molecular imaging of esophageal cancer. Molecular Imaging. DOI: 10.1155/2022/5447290. Epub ahead of print.
Kennedy GT, Azari FS, Bernstein E, Din A, Marfatia I, Deshpande C, Kucharczuk JC & Singhal S. (2022). Three dimensional near-infrared specimen mapping can identify the distance from the tumor to the surgical margin during resection of pulmonary ground glass opacities. Molecular Imaging and Biology. DOI: 10.1007/s11307-022-01750-0. Epub ahead of print.
Kennedy GT, Azari FS, Bernstein E, Nadeem B, Chang A, Segil A, Sullivan NT, Encarnado E, Deshpande C, Kucharczuk JC, Leonard K, Low PS, Chen S, Criton A & Singhal S. (2022). Targeted detection of cancer cells during biopsy allows real-time diagnosis of pulmonary nodules. European Journal of Nuclear Medicine and Molecular Imaging, 49(12), 4194–4204. DOI: 10.1007/s00259-022-05868-9. 
Kennedy GT, Azari FS, Chang A, Nadeem B, Bernstein E, Segil A, Din A, Marfatia I, Okusanya O, Keating J, Predina J, Newton A, Kucharczuk J & Singhal S. (2022). Comparative experience of short versus long wavelength fluorophores for folate receptor-targeted intraoperative molecular imaging of lung cancer. Annals of Surgery, 276(4), 711–719. DOI: 10.1097/SLA.0000000000005596. 
Azari F, Kennedy GT, Chang A, Bernstein E, Nadeem B, Pèlegrin A, Cailler F, Sullivan NT, Kucharczuk J & Singhal S. Glycoprotein receptor CEACAM5-targeted intraoperative molecular imaging tracer in NSCLC. (2022). Annals of Thoracic Surgery. DOI: 10.1016/j.athoracsur.2022.05.019. Epub ahead of print.
Kennedy GT, Azari FS, Bernstein E, Nadeem B, Chang A, Segil A, Carlin S, Sullivan N, Encarnado E, Deshpande C, Kularatne S, Gagare P, Thomas M, Kucharczuk JC, Christien G, Lacombe F, Leonard K, Low PS, Criton A & Singhal S. (2022). Targeted detection of cancer at the cellular level during biopsy by near-infrared confocal laser endomicroscopy. Nature Communications, 13(1), 2711. DOI: 10.1038/s41467-022-30265-z
Kennedy GT, Azari FS, Bernstein E, Marfatia I, Din A, Deshpande C, Galvis N, Sorger J, Kucharczuk J & Singhal S. (2022). First-in-human results of targeted intraoperative molecular imaging for visualization of ground glass opacities during robotic pulmonary resection. Translational Lung Cancer Research, 11(8), 1567–1577. DOI: 10.21037/tlcr-21-1004
Kennedy GT, Azari FS, Bernstein E, Nadeem B, Chang AE, Segil A, Sullivan N, Marfatia I, Din A, Desphande C, Kucharczuk JC, Low PS & Singhal S. (2022). A prostate specific membrane antigen-targeted near-infrared conjugate for identifying pulmonary squamous cell carcinoma during resection. Molecular Cancer Therapeutics, 21(4), 546–554. DOI: 10.1158/1535-7163.MCT-21-0821. 
Azari FS, Zhang K, Kennedy GT, Bernstein E, Chang A, Nadeem B, Segil A, Din A, Marfatia I, Deshpande C, Kucharczuk J, Delikatny J & Singhal S. (2022). Effects of light absorbing carbons in intra-operative molecular imaging guided lung cancer resections. Molecular Imaging and Biology. DOI: 10.1007/s11307-021-01699-6. Epub ahead of print.
Kennedy GT, Azari FS, Bernstein E, Desphande C, Din A, Marfatia I, Kucharczuk JC, Delikatny EJ, Low PS & Singhal S. (2021). 3D specimen mapping expedites frozen section diagnosis of non-palpable ground glass opacities. Annals of Thoracic Surgery. DOI: 10.1016/j.athoracsur.2021.09.069.
Kennedy GT, Azari FS, Bernstein E, Marfatia I, Din A, Kucharczuk JC, Low PS & Singhal S. (2021). Targeted intraoperative molecular imaging for localizing nonpalpable tumors and quantifying resection margin distances. JAMA Surgery. DOI: 10.1001/jamasurg.2021.3757. 
Azari F, Louka KL, Kennedy G, Bernstein E, Babayev SN, Cooper K & Singhal S. (2021). Minimally invasive resection of rare symptomatic posterior mediastinal Mullerian tumor. Archives of Clinical and Medical Case Reports 5: 575-582.
Azari F, Kennedy G, Bernstein E, Delikatny J, Lee JYK, Kucharczuk J, Low PS & Singhal S. (2021). Evaluation of OTL38-generated tumor-to-background ratio in intraoperative molecular imaging-guided lung cancer resections. Molecular Imaging and Biology, DOI: 10.1007/s11307-021-01618-9.
Azari F, Kennedy G, Bernstein E, et al. (2021). Intraoperative molecular imaging: A review of 2020 conference proceedings. Journal of Biomedical Optics, DOI: 10.1117/1.JBO.26.5.050901.
Kennedy G, Azari F, Newton A, Bernstein E, Fraker DL, Wachtel H & Singhal S. (2021). Use of near-infrared molecular imaging for localizing visually occult parathyroid glands in ectopic locations. JAMA Otolaryngology-Head & Neck Surgery, DOI: 10.1001/jamaoto.2021.0615.
Kroshus E, Hoopes T, Bernstein E, Chrisman SPD & Rivara FP. (2019). Direct verbal communication by parents, pressure related to sport achievement, and concussion safety in youth football. Journal of Health Communication, DOI: 10.1080/10810730.2019.1668512.
Albayram O, Angeli P, Bernstein E, Baxley S, Gao Z, Lu KP & Zhou XZ. (2018). Targeting prion-like cis phosphorylated tau pathology in neurodegenerative diseases. Journal of Alzheimer's disease & Parkinsonism, 8(3), 443.

Conference Abstracts and Presentations

Bernstein E, Lemmon EA, Jenk AC, Assi SS & Mauck RL. (2022). IL-1Ra delivery restores phenotype and preserves matrix in inflammatory meniscus micro-tissues. 2023 Orthopedic Research Society Annual Meeting, poster presentation. Dallas, TX
Lemmon EA, Burt KG, Bernstein E, Sharp EE, Stoeckle BD, Laforest L, Scanzello CR, Mauck RL & Agnello KA. (2022). Anakinra reduces inflammatory pathways activated in canine synovium after cranial cruciate ligament injury. 2023 Orthopedic Research Society Annual Meeting, poster presentation. Dallas, TX.
Assi S, Bernstein E, Bonnevie ED, Sharp E & Mauck R. (2022). Superficial Meniscus Cells are Highly Proliferative and Migratory and Generate Functional Tissue. 2023 Orthopedic Research Society Annual Meeting, podium presentation. Dallas, TX.
Kennedy GT, Azari FS, Nadeem B, Chang A, Segil A, Bernstein E, Din A, Marfatia I, Okusanya O, Keating J, Predina J, Newton A, Kucharczuk J & Singhal S. (2022). The First 500 Pulmonary Resections Guided by Intraoperative Molecular Imaging: Lessons from a Single Institutional Experience. 142nd Annual Meeting of the American Surgical Association, podium presentation. Chicago, IL.
Bernstein E, Kennedy G, Azari F, Frenzel Sulyok L, Bryski M & Singhal S. (2021). Cathepsin-Targeted Probe for Detection of Surgical Margins During Pulmonary Resection. 2021 Academic Surgical Congress, poster presentation. Virtual Congress.
Bernstein E & Kroshus E. (2018). Concussion Safety Communication Among Limited English Proficient Parents of Hispanic Youth Soccer Players. Seattle Children’s Research Institute Summer Undergraduate Research Symposium, poster presentation. Seattle, WA.
Azari F, Kennedy GT, Zhang K, Bernstein E, Maki RG, Gaughan C, Jarrar D, Pechet T, Kucharczuk J & Singhal S. (2022). Impact of intraoperative molecular imaging after fluorescent-guided pulmonary metastasectomy for sarcoma. Journal of the American College of Surgeons. 234(5):748-758. doi: 10.1097/XCS.0000000000000132. 
Kennedy GT, Azari FS, Bernstein E & Singhal S. (2021). Evaluation of a novel GCP2-targeted tracer for the intraoperative molecular imaging of pulmonary squamous cell carcinoma. Journal of the American College of Surgeons. 233(5):S259. doi: 10.1016/j.jamcollsurg.2021.07.535.

 

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