Isaac E. Erickson, Ph.D.
Graduate Student in Bioengineering
NSF Graduate Research Fellow (2007-2010)
University of Pennsylvania
Hometown
Ogden, Utah
Education
Ph.D. Bioengineering, 2011, University of Pennsylvania
B.S. Bioengineering, 2006, University of Utah
Areas of Special Interest
Scientific pursuits include functional cartilage tissue regeneration, bioreactor development, and mesenchymal stem cell research. Personal interests include mountain biking, competitive eating (weak), climbing trees, jumping off stuff, driving car in reverse, and teaching "crazy" to our daughter when my sweet wife isn't looking.
Publications
Erickson IE, van Veen SC, Sengupta S, Kestle SR, Burdick JA, Mauck RL. Age-Dependent Cartilage Matrix Formation by Bovine Mesenchymal Stem Cells in 3D Culture. Clinical Orthopaedics & Related Research, 2010, in press.
Erickson IE, Huang AH, Sengupta S, Kestle S, Burdick JA, Mauck RL. Macromer Density Influences Mesenchymal Stem Cell Chondrogenesis and Maturation in Photocrosslinked Hyaluronic Acid Hydrogels. Osteoarthritis & Cartilage, 2009, 17(12):1639-48.
Erickson IE, Huang AH, Chung C, Li RT, Burdick JA, Mauck RL. Differential Maturation and Structure-Function Relationships in MSC and Chondrocyte Seeded Hydrogels. Tissue Engineering Part A, 2009, 15(5):1041-52.
Chung C, Erickson IE, Mauck RL, Burdick JA. Differential Behavior of Auricular and Articular Chondrocytes in Hyaluronic Acid Hydrogels. Tissue Engineering Part A, 2008, 14(7): 1121-31.
Brey DM, Erickson IE, Burdick JA. Influence of macromer molecular weight and chemistry on poly(beta-amino ester) network properties and initial cell interactions. Journal of Biomedical Materials Research: Part A, 2008, 85(3): 731-41.
Conference Abstracts
Erickson IE, Kestle SR, Kim M, Zellars KH, Burdick JA, Dodge GR, Mauck RL, "µCT and Mechanical Analysis of Maturation and Integrative Cartilage Repair in MSC-Seeded HA Hydrogels," Tissue Engineering & Regenerative Medicine International Society-North America Annual Conference and Exposition, Orlando, FL, December 5-8, 2010, paper #T2010-1239.
Erickson IE, Kestle SR, Kim M, Zellars KH, Dodge GR, Burdick JA, Mauck RL, "In Vitro Maturation and Integration of Engineered Chondrogenic Stem Cell-Seeded Hyaluronic Acid Hydrogels," The 57th Annual Meeting of the Orthopaedic Research Society, Long Beach, CA, January 13-16, 2011.
Erickson IE, Kestle SR, Zellars KH, Burdick JA, Mauck RL, "High Density MSC-Seeded Hyaluronic Acid Constructs Produce Engineered Cartilage with Near-Native Properties," The 57th Annual Meeting of the Orthopaedic Research Society, Long Beach, CA, January 13-16, 2011.
Erickson IE, van Veen SC, Sengupta S, Kestle SR, Burdick JA, Mauck RL, " Effects of Aging and TGF-Beta 3 on Chondrocyte and Mesenchymal Stem Cell Matrix Formation," Proceedings of ASME 2010 Summer Bioengineering Conference, Naples, FL, June 15-19, paper #19517.
Kim M, Erickson IE, Burdick JA, Dodge GR, Mauck RL, "Differential Chondrogenic Potential of Human and Bovine Mesenchymal Stem Cells in Agarose and Photocrosslinked Hyaluronic Acid Hydrogels," Proceedings of ASME 2010 Summer Bioengineering Conference, Naples, FL, June 15-19, paper #19461.
Erickson IE, Kestle SR, Farrell MJ, Burdick JA, Mauck RL, "Macromer Density Mediates Mesenchymal Stem Cell Response to Dynamic Compression in Photo-Crosslinked Hyaluronic Acid Hydrogels," Transactions of the 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, March 6-9, 2010, volume 35:1286.
Erickson IE, Kestle SR, Burdick JA, Mauck RL, "In Vitro Cartilage Integration of MSC-Seeded Hyaluronic Acid Constructs," Transactions of the 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, March 6-9, 2010, volume 35:1337
Kim M, Erickson IE, Yoder J, Mauck RL, Witschey W, Fenty M, Reddy R, Dodge GR, "Evaluation of Integrative Cartilage Repair with Scaffold-Free Constructs," Transactions of the 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, March 6-9, 2010, volume 35:30.
Ionescu LC, Garcia GH, Erickson IE, Guevara JL, Shah RP, Sennett BJ, Mauck RL, "In Vitro Meniscus Integration is Age Dependent," Transactions of the 56th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, March 6-9, 2010, volume 35:927.
Erickson IE, Sengupta S, Kestle S, Chung C, Burdick JA, Mauck RL, "Macromer Concentration Influences Gel Mechanics, Diffusivity, and Maturation of MSC-Seeded HA Hydrogels," Transactions of the 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, NV, February 22-25, 2009, volume 34:1723
Erickson IE, Chung C, Burdick JA, Mauck RL, Hyaluronic Acid Macromer Concentration Influences Functional MSC Chondrogenesis in Photocrosslinked MSC-Laden Hydrogels," Proceedings of ASME 2008 Summer Bioengineering Conference, Marco Island, FL, June 25-29, paper #193096.
Erickson IE, Huang AH, Chung C, Li RT, Burdick JA, Mauck RL, "Hydrogel Effects on Long-Term Maturation of Chondrocyte and MSC-Laden Hydrogels," Transactions of the 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, March 2-5, 2008, volume 33:0557.
Brey DM, Erickson IE, Tan A, Burdick JA, "Controlling Polymer Properties and Cellular Interactions through Poly(alpha-amino ester) Macromer Structure," Society for Biomaterials Annual Meeting, Chicago, IL, April, 2007.
Erickson IE, Yang YI, Fitzpatrick K, Kirker KR, Massey MF, Shelby J, "Improved Viability of Adipose-Derived Adult Stem Cells Using Hyaluronan as a Media Supplement," Biointerface 2005: The Annual Surfaces in Biomaterials Foundation Symposium, Minneapolis, MN, October 24-26, 2005.