Mauck Laboratory

Kevin Burt, PH.D

Post Doc
University of Pennsylvania

Hometown

Butte, MT

Education

Columbia University, Ph.D. in Biomedical Engineering
Montana State University, B.S. in Civil Engineering

Areas of Special Interest

Immunology, Macrophage Biology, Mechanobiology, Pre-clinical models

Publications

Burt KG, Viola DC, Lisiewski LE, Lombardi J, Genualdi J, Amorosa L, Chahine NO. “An in-vivo model of Ligamentum flavum hypertrophy capturing early-stage inflammation & later stage hypertrophy.” [In review, JOR Spine]

Shah BS, Burt KG, Jacobsen T, Fernandes TD, Alipui DO, Weber KT, Levine M, Chavan SS, Yang H, Tracey KJ, Chahine NO. "High mobility group box‐1 induces pro‐inflammatory signaling in human nucleus pulposus cells via toll‐like receptor 4‐dependent pathway." Journal of Orthopaedic Research® 37.1 (2019): 220-231.

Conference Abstracts and Presentations

NF-κB over-activation leads to disc degeneration and the recruitment of mechanoresponsive macrophages. 2022 UC – Next Seminar Series, UCSB Santa Barbara, CA. [Presentation]

An in-vivo model of Ligamentum flavum hypertrophy capturing early stage inflammation & later stage hypertrophy. 2022 Orthopaedic Research Society Annual Meeting, Tampa, FL. [Podium]

Hydrostatic pressurization activates an inflammatory resolving macrophage through cytoskeletal related pathways. 2022. Orthopaedic Research Society Annual Meeting, Tampa, FL. [Poster]

HMGB1 exhibits a sustained regional activation following injury of the intervertebral disc. 2022 Orthopaedic Research Society Annual Meeting, Tampa, FL. [Poster]

Hydrostatic pressurization activates an inflammatory resolving macrophage through cytoskeletal related pathways. 2022. BMES - Cellular and Molecular Bioengineering, Indian Wells, CA. [Podium]

HMGB1 exhibits a sustained regional activation following injury of the IVD. 2021. 10th Annual Musculoskeletal Repair and Regeneration Symposium. New York, NY. [Poster presentation]

Hydrostatic pressurization activates an inflammatory resolving macrophage through cytoskeletal related pathways. 2021. 10th Annual Musculoskeletal Repair and Regeneration Symposium. New York, NY. [Poster presentation]

Hydrostatic Pressure Loading of Macrophages Regulates Immune Function. 2021. Orthopaedic Research Society Annual Meeting, Long Beach, CA. [Poster]

Activation of IKKβ causes severe intervertebral disc degeneration in the mouse caudal spine. 2021. Orthopaedic Research Society Annual Meeting, Long Beach, CA. [Poster]

Hydrostatic Pressure Loading of Macrophages Regulates Immune Function. 2020. Summer Biomechanics, Bioengineering and Biotransport Conference, Vail, CO. [Podium]

In-vivo Deletion of HMGB1 Protects Against Inflammatory Induced Disc Degeneration. 2020. Orthopaedic Research Society Annual Meeting, Phoenix, AZ. [Podium]

In-vivo Deletion of HMGB1 Protects Against Inflammatory Induced Disc Degeneration. 2019. Philadelphia Spine Research Society International Spine Research Symposium, Skytop, PA. [Poster]

HMGB1 Induces Inflammation and ECM Degradation in a 3D Model of Human Nucleus Pulposus Cells. 2019. Orthopaedic Research Society Annual Meeting, Austin, TX. [Podium]

HMGB1 Induces Inflammation and ECM Degradation in a 3D Model of Human Nucleus Pulposus Cells. 2018. Philadelphia Spine Research Symposium, Philadelphia, PA [Podium]

Calcium Precipitation and Trace Metal Co-Precipitation during Fluid Flow and Mixing. 2017. Student Research Celebration, Bozeman, MT. [Poster]

Awards

UC – Next Seminar Series Speaker 2022
2022 ORS Spine Section Podium Presentation Award Recipient 2022
2022 BMES-CMBE Graduate Student Travel Award 2022
2020 ORS Spine Section Podium Presentation Award Recipient 2020
Global Ambassador, Montana State University (International Affairs Department) 2016
Martin E. Moss Memorial Scholarship Recipient, Montana State University 2016
John H. Morrison Scholarship Recipient, Montana State University 2014
Martin & Dixie Jacobson Scholarship Recipient, Montana State University 2013
MSU Merit Award, Montana State University 2012
MT Com/Ed Foundations Scholarship Recipient, Montana State University 2012

More about yourself

Being a doctor, scientist, AND cowboy is a tough job... but someone has to do it.

Academic Twitter: @kevin_gburt

 

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