Mauck Laboratory

Nicole Belkin, M.D.

Resident, Orthopaedic Surgery
University of Pennsylvania

Hometown

Port St. Lucie, FL

Education

M.D. University of Florida, 2009 B.S. Health Science, 2005, University of Florida

Areas of Special Interest

Orthopaedic Surgery - Arthroscopic, Minimally Invasive Procedures and Cartilage Conservation. Fracture Healing. Biomedical Engineering in Orthopedics. Personal interests include The Beach, Sports (particularly Rugby), Cooking, and Good Beer.

Publications

Rumore-Maton, B. J. Elf, N. Belkin, B. Stutevoss, F. Seydel, E. Garrigan, S.A. Litherland: M-CSF and GM-CSF Regulation of STAT5Activation and DNA Binding in Myeloid Cell Differentiation is Disrupted in Nonobese Diabetic (NOD) Mice. Clinical & Developmental Immunology Jan: 769-795, 2009

Seydel, F., E. Garrigan, B. Stutevoss, N. Belkin, B. Makadia, J. Carter, J.-D. Shi, A. Davoodi-Semiromi, M. McDuffie, S. A. Litherland: GM-CSF Induces STAT5 Binding at Epigenetic Regulatory Sites within the Csf2 Promoter of Nonobese Diabetic (NOD) Mouse Myeloid Cells. J Autoimmunity 31(4): 377-384, 2008

Litherland, S.A., K.M. Grebe, N.S. Belkin, E. Paek, J. Elf, M. Atkinson, L. Morel, M.J. Clare-Salzler, M.J. McDuffie: Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and GM-CSF overproduction. J Immunology. 175(7): 4561-4565, 2005

Litherland, S.A., T.X. Xie, K.M. Grebe, A. Davoodi-Semiromi, J. Elf, N.S. Belkin, L.L. Moldawer, M.J. Clare-Salzler: Signal Transduction Activator of Transcription 5 (STAT5) Proteins are Dysfunctional in Autoimmune Monocytes & Macrophages. J Autoimmunity. 24: 297-310, 2005

Abstracts

Garrigan, E, Z. Han, F Seydel, NS Belkin, C Riggs, M Amick, A Cdebaca, T Pilant, R Bober, C Wasserfall, M Atkinson, MJ Clare-Salzler, L Morel, M McDuffie, and S A Litherland. 2010. A Model for Studying the Impact of Nurture on Nature: Development of Diabetes in Multicongenic Mice with an Epigenetic Gene Expression Dysregulation Defect from the Nonobese Diabetic Mouse (NOD); ADA poster presentation, June 2010, Orlando, FL.

Garrigan, E., F. Seydel, B. Stutevoss, N. Belkin, M. Clare-Salzler, M. Atkinson, L. Yang, A.B. Peck, L. Morel, M. McDuffie, A. Davoodi-Semiromi, and S. A. Litherland. Nonobese Diabetic (NOD) Congenic Mouse Analysis Defines an Idd4.3 Sequence Crucial to GM-CSF Regulation of STAT5 Binding and Associated Epigenetic Changes at the Csf2 and Ptgs2 Regulatory Sequences in Macrophages; Keystone Symposium; Jaks and STATs. Colorado Springs. Jan 2007.

F. Seydel, E. Garrigan, K. Pauley, B. Stutevoss, N. Belkin, M. McDuffie, L. Yang, L. Morel, and S.A. Litherland: STAT5 Dysfunction in Autoimmune Myeloid Cells; 2006 Gene Expression and Signal Transduction in the Immune System, Cold Spring Harbor Laboratory meeting and UF COM Research Day Presentation; April 2006.

E. Garrigan, F. Seydel, K. Pauley, B. Stutevoss, N. Belkin, M. McDuffie, L. Morel, and S.A. Litherland: GM-CSF Dysregulation of STAT5 in Autoimmune Myeloid Cells; 2006 Gene Expression and Signal Transduction in the Immune System, Cold Spring Harbor Laboratory meeting and UF COM Research Day Presentation;. April 2006.

Belkin, N.S., and S.A. Litherland: PIAS3 & STAT5 Interactions Disrupted in Nonobese Diabetic (NOD) Mice; FASEB/AAI Experimental Biology Conference. San Diego, CA. and UF COM Research Day Presentations; April 2005.

J. Elf and N. Belkin, B. Rumore-Maton, M. J. Clare-Salzler, M. McDuffie, and S. A. Litherland: Dysregulation of Signal Transduction Activators of Transcription 5 (STAT5) in Autoimmune Type 1 Diabetes (T1D). International FOCIS Meeting, Montreal, Canada. Awarded FOCIS Travel Award for oral & poster presentation; July 2004.

Awards

  • 2008, Mark W. Herbold Memorial Award, U of FL COM
  • 2005-9, UF COM Class of 2009 Executive Board 
  • 2005, Suma Cum Laude, University of Florida 2005, Academic Excellence Award, U of Fl, College of Health Sciences 
  • 2004, USA Rugby Collegiate All-American, First Team 
  • 2004, UF Women's Club Scholarship 
  • 2004, Outstanding Undergraduate Research Award, University of Florida 2004, University Scholars Award for Summer Research 
  • 2002-4, University of Florida Women's Rugby Team Captain
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