Dynamic Light Scattering

Dynamic light scattering (DLS) is a technique used to measure the size of particles dispersed in a liquid. It is also known as photon correlation spectroscopy (PCS) or quasi-elastic light scattering (QELS). DLS works by measuring the Brownian motion of macromolecules in solution. This motion is caused by solvent molecules bombarding the macromolecules. The larger the particle, the slower the Brownian motion.

• The Nanobrook 90Plus Submicron Particle Sizer (DLS) Instrument is a cuvette-based instrument with disposable cuvettes that allow for the recording of data from samples as small as 50 uLs in volume. The instrument is operated by a dedicated computer for data collection and analysis.
• The Wyatt Dynapro Dynamic Light Scattering (DLS) Instrument is a cuvette-based instrument with specialized cuvettes allow for the recording of data from samples as small as 4 uL in volume. The instrument is operated by a dedicated computer for data collection and analysis.

Contact: Kushol Gupta | kgupta@pennmedicine.upenn.edu
Location: 810 Stellar-Chance Laboratories