Differential Scanning Calorimetry

Differential Scanning Calorimetry (DSC) is a technique that measures how a material's heat capacity changes with temperature. It's used to analyze the stability of proteins and other biomolecules, as well as metals and other materials. 
DSC works by heating or cooling a sample of known mass and tracking changes in its heat capacity. The difference in heat flow between the sample and a reference is monitored as a function of time or temperature

  • MicroCal VP-DSC Microcalorimeter with temperature control in the range of -10 to 130 Celsius for measurement of temperature midpoint (Tm), enthalpy (dH), and heat capacity change (dCp). The instrument is operated by a dedicated computer for data collection and analysis.

Contact: Kushol Gupta | kgupta@pennmedicine.upenn.edu
Location: 810 Stellar-Chance Laboratories