Isothermal Titration Calorimetry

Isothermal titration calorimetry (ITC) is a technique that measures the heat released or absorbed during a chemical reaction to determine the thermodynamics of binding reactions. It is a label-free method used to measure the binding of any two molecules that release or absorb heat upon binding. ITC is a gold standard method for the measurement of the thermodynamic parameters of biomolecular interactions, including: Affinity, Stoichiometry, and the determination of thermodynamic parameters (dH, dS). 

  • The MicroCal ITC200 Microcalorimeter includes temperature control, 200 uL sample cell and 40 uL injection syringe. The instrument is operated by a dedicated computer for data collection and analysis.

Contact: Kushol Gupta |
Location: 810 Stellar-Chance Laboratories