Matrix-Assisted Laser Desorption/Ionization Time-of-Flight

This is a soft ionization mass spectrometry approach that allows for the analysis of a variety of biological macromolecules and large organic molecules. Sample that is mixed with a matrix is irradiated with a pulsed laser, creating analyte molecules that are ionized and accelerated to yield mass information.

  • The Bruker Microflex LHF MALDI-TOF Mass Spectrometer is a bench-top instrument designed for for a variety of routine applications in the analysis of proteins and small molecules. 

Contact: Leland Mayne | mayne@pennmedicine.upenn.edu
Location: 1010 Stellar-Chance Laboratory