Chuan Wu, MD, PhD

Stadtman Investigator
Experimental Immunology Branch

The central focus of my lab is to understand how intercellular interactions regulate immune homeostasis on mucosal surface, particularly neuron-immune crosstalk for intestinal barrier integrity. We are also exploring new therapeutic approaches for patients with intestinal inflammation and related extraintestinal manifestations. We are utilizing interdisciplinary approaches to elucidate the crosstalk between the nervous system, microbial pathogens and the immune system. Main questions we are investigating include: 1. Reciprocal regulations between the host and gut microbiota; 2. Neuro-immune crosstalk for the mucosal homeostasis in lungs and gastrointestinal tract; 3. Identification of novel targets in the intestinal epithelium for IBD treatment. For more information, please visit our lab website: https://irp.nih.gov/pi/chuan-wu

Suggested Penn mentors: Joe Zackular, Michael Abt, Gary Wu, Christoph Thaiss