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Clayton Otter

Clayton Otter

Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2019

Rotations:

  • Rahul Kohli

Pierce Nathanson

Pierce Nathanson

Microbiology, Virology, and Parasitology
Degree: VMD/PhD
Matriculation Year: 2008

Advisor(s):

  • Alice Chen-Plotkin

Rotations:

  • Susan Weiss
  • Alice Chen-Plotkin
  • David Artis
  • Aaron Gitler

In the vast majority of cases of amyotrophic lateral sclerosis and ~50% of the cases of frontotemporal lobar degeneration, pathology is characterized by mislocalization and…Read More

In the vast majority of cases of amyotrophic lateral sclerosis and ~50% of the cases of frontotemporal lobar degeneration, pathology is characterized by mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43) in neurons and glia. Research has emphasized TDP-43’s role as an RNA binding protein and despite in vitro characterization of TDP-43’s ability to bind DNA, a genome-wide DNA binding map has yet to be defined. Therefore, I am studying the DNA binding characteristics of TDP-43 in human cells via ChIP-Seq and subsequent biochemical analysis. 

Dana Bellissimo

Dana Bellissimo

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2011

Project Title: The regulation of myeloid inflammatory responses by RUNX1: roles in normal and malignant hematopoiesis

Advisor(s):

  • Dwight Gilliland
  • Nancy Speck

Rotations:

  • Eric Brown
  • Andy Minn
  • Nancy Speck
  • Mitch Weiss

Kaitlyn Shen

Kaitlyn Shen

Degree: MD/PhD
Matriculation Year: 2019

Kevin Sun

Kevin Sun

Degree: MD/PhD
Matriculation Year: 2019

Napasorn Kuprasertkul

Napasorn Kuprasertkul

Degree: MD/PhD
Matriculation Year: 2019

Raymond Ng

Raymond Ng

Degree: MD/PhD
Matriculation Year: 2019

Emily Lubin

Emily Lubin

Degree: MD/PhD
Matriculation Year: 2019

Prateek Sharma

Prateek Sharma

Degree: MD/PhD
Matriculation Year: 2019

Ethan Fein

Ethan Fein

Degree: MD/PhD
Matriculation Year: 2019

Benjamin Kahn

Benjamin Kahn

Degree: MD/PhD
Matriculation Year: 2019

Zachary Gardner

Zachary Gardner

Degree: MD/PhD
Matriculation Year: 2019

Brian Franklin

Brian Franklin

Degree: MD/PhD
Matriculation Year: 2019

Nathan Coffey

Nathan Coffey

Degree: MD/PhD
Matriculation Year: 2018

Julia Chini

Julia Chini

Degree: MD/PhD
Matriculation Year: 2019

Jayesh Tandel

Jayesh Tandel

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Understanding the transcriptome of sexual stages of Cryptosporidium parvum- an important prerequisite in unravelling the programming of the lifecycle of the parasite

Advisor(s):

  • Boris Striepen

Alexis Gibson

Alexis Gibson

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Genome Wide CRISPR/Cas9 Knockout Screen Identifies Host Genes Important for Cryptosporidium parvum Infection

Advisor(s):

  • Boris Striepen

Kay Foos

Kay Foos

Cancer Biology
Degree: VMD/PhD
Matriculation Year: 2019

Joshua Shaffer

Joshua Shaffer

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Kathryn Wellen

Siera Rosen

Siera Rosen

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Edward Morrisey

Yohaniz Ortega-Burgos

Yohaniz Ortega-Burgos

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Elizabeth Bhoj

Ruchi Patel

Ruchi Patel

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Andrei Thomas-Tikhonenko

Stefan Peterson

Stefan Peterson

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Maayan Levy

Brianne Roper

Brianne Roper

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Elana Pyfrom

Elana Pyfrom

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Marisa Bartolomei

Jacqueline Plesset

Jacqueline Plesset

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Ben Stanger

Ronit Schwartz Wertman

Ronit Schwartz Wertman

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Igor Brodsky

Olivia Pilling

Olivia Pilling

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Michael Silverman

Keenan O'Dea

Keenan O'Dea

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Sunny Shin

Kara Nelson

Kara Nelson

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Jeremy Wang

Daniel Morreale

Daniel Morreale

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Joseph St Geme

Erick Mitchell-Velasquez

Erick Mitchell-Velasquez

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Maureen Murphy

Lydia Mendoza

Lydia Mendoza

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Scott Hensley

Kurtis McCannell

Kurtis McCannell

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Mia Levine

Katherine Labella

Katherine Labella

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Thomas DeRaedt

Kylie Konrath

Kylie Konrath

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Daniel Kulp

Max Klapholz

Max Klapholz

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Andy Minn

Melissa Kim

Melissa Kim

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Panteleimon Rompolas

Valerie Irizarry-Negron

Valerie Irizarry-Negron

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Dmitry Gabrilovich

Caitlin Hopkins

Caitlin Hopkins

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Hamid Bassiri

Kevin Hernandez

Kevin Hernandez

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Scott Hensley

Rumi Habib

Rumi Habib

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Daniel Kulp

Adam Ferrari

Adam Ferrari

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Constantinos Koumenis

Alejandra Fausto

Alejandra Fausto

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Kellie Jurado

Stephen Carro

Stephen Carro

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Laurence Eisenlohr

Maria Carrera

Maria Carrera

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Montserrat Anguera

Sarah Campbell

Sarah Campbell

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Naiara Aquizu Lopez

Benjamin Caiello

Benjamin Caiello

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Bradley Johnson

Shovik Bandyopadhyay

Shovik Bandyopadhyay

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

  • Ivan Maillard

June Yang

June Yang

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Jianxin You

Rotations:

  • Jianxin You
  • Ronald Collman
  • Dennis Kolson

Vincent Wu

Vincent Wu

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Role of KLRG1 signaling on CD8+ T-cells during chronic HIV infection

Advisor(s):

  • Michael Betts

Rotations:

  • Frederic Bushman
  • Michael Betts
  • Elizabeth Grice

Ellen White

Ellen White

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

  • Elizabeth Grice

Rotations:

  • Elizabeth Grice
  • Michael Silverman

Monica Wei

Monica Wei

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017

Rotations:

  • Matthew Weitzman
  • Kai Tan

Louis Taylor

Louis Taylor

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Project Title: Replication and tropism of Redondoviridae, a new family of DNA viruses of the human oro-respiratory tract

Advisor(s):

  • Frederic Bushman

Rotations:

  • Frederic Bushman
  • Paula Oliver
  • Matthew Weitzman

Katherine Strelau

Katherine Strelau

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Defining the proteins responsible for establishing C. parvum infection

Advisor(s):

  • Boris Striepen

Rotations:

  • Carolina Lopez
  • Boris Striepen
  • David Weiner

Gregory Sousa

Gregory Sousa

Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2014

Advisor(s):

  • Michael Povelones

Rotations:

  • Matthew Hayes
  • Michael Povelones
  • De'Broski Herbert

Alexander Smith

Alexander Smith

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Joseph Zackular

Rotations:

  • James Riley
  • Joseph Zackular
  • Michael Silverman

Nawar Naseer

Nawar Naseer

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Sunny Shin

Rotations:

  • Scott Hensley
  • Sunny Shin
  • Paul Planet

I am studying how the human immune system recognizes Salmonella, which causes diarrheal disease. Salmonella initially invades and replicates within intestinal epithelial cells by using…Read More

I am studying how the human immune system recognizes Salmonella, which causes diarrheal disease. Salmonella initially invades and replicates within intestinal epithelial cells by using type III secretion systems (T3SSs) to inject proteins into host cells. I am studying the role of a cytosolic sensor called human NAIP (hNAIP) during Salmonella infection. I will determine which T3SS components are sensed by hNAIP, what response hNAIP mounts, and whether these responses control bacterial infection.

Victoria Lovins

Victoria Lovins

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Elizabeth Grice

Rotations:

  • Elizabeth Grice
  • David Weiner
  • Carolina Lopez

Nadia Kadry

Nadia Kadry

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Joseph St Geme

Rotations:

  • Joseph St Geme
  • Frederic Bushman
  • Ronald Collman

Philip Hicks

Philip Hicks

Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2016

Project Title: The role of retrograde trafficking during cellular entry by severe fever with thrombocytopenia syndrome virus

Advisor(s):

  • Paul Bates

Rotations:

  • Ronald Harty
  • Paul Bates
  • Elizabeth White

Beatrice Herrmann

Beatrice Herrmann

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Igor Brodsky

Rotations:

  • Joseph St Geme
  • Igor Brodsky
  • Christoph Thaiss

Trevor Griesman

Trevor Griesman

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Innate immunity in primary neurons: specialized responses to viral infection

Advisor(s):

  • Sara Cherry

Rotations:

  • Scott Hensley
  • Paul Bates
  • Sara Cherry

Lavinia Gonzalez

Lavinia Gonzalez

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Role of cytoplasmic stress granules during Respiratory Syncytial virus infection containing high levels of defective viral genomes

Advisor(s):

  • Carolina Lopez

Rotations:

  • Una O’Doherty
  • Carolina Lopez
  • Sara Cherry

James Gesualdi

James Gesualdi

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: The Blood Meningeal Barrier Orchestrates the Development of Autoimmune Neuroinflammatory Responses

Advisor(s):

  • Jorge Alvarez

Rotations:

  • Jorge Alvarez
  • Paul Lieberman
  • Katharine Bar

Jennifer Dumaine

Jennifer Dumaine

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Cryptosporidium exports proteins to the cytoplasm of the epithelial host cell

Advisor(s):

  • Boris Striepen

Marcus Bolton

Marcus Bolton

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Scott Hensley

Rotations:

  • George Shaw
  • Scott Hensley
  • David Allman

Anya Bauer

Anya Bauer

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Project Title: Development and Validation of SHIV-Macaque Models for HIV-1 Infection

Advisor(s):

  • Katharine Bar

Rotations:

  • Ronald Collman
  • Katharine Bar
  • James Riley

Antonia Bass

Antonia Bass

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Project Title: Elucidating the mechanisms underlying noncanonical inflammasome responses to Legionella pneumophila

Advisor(s):

  • Sunny Shin

Rotations:

  • Michael Povelones
  • Sunny Shin
  • Sara Cherry

Shannon Christensen

Shannon Christensen

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Scott Hensley

Rotations:

  • Matthew Weitzman
  • Paul Bates
  • Susan Weiss
  • Scott Hensley

I will be studying antibody isotype, glycosylation status, and functionality in response to flavivirus and influenza infections.

I will be studying antibody isotype, glycosylation status, and functionality in response to flavivirus and influenza infections.

Daniel Akuma

Daniel Akuma

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Defining the Interaction between LPS and Caspase-11 in the Non-Canonical Inflammasome

Advisor(s):

  • Igor Brodsky

Rotations:

  • Igor Brodsky
  • Jianxin You
  • Michael Granato

Mary Margaret Addison

Mary Margaret Addison

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Laurence Eisenlohr

Rotations:

  • Beatrice Hahn
  • Michael Betts
  • Laurence Eisenlohr

Despite HIV's significant global health importance, there is still much to learn about the ways in which the immune system detects and responds to this…Read More

Despite HIV's significant global health importance, there is still much to learn about the ways in which the immune system detects and responds to this virus. Robust HIV-specific CD4+ T cell responses are associated with decreased viral load and a slower progression to AIDS, and will likely be essential for generating protective HIV vaccine responses. However, CD4+ T cells must be activated before they can contribute to the immune response.
This activation requires the binding of T cell receptors on the surface of the CD4+ T cell to antigen-derived peptides (epitopes) displayed in complex with MHCII molecules (MHCII) on the surface of an antigen presenting cell (APC). Thus, understanding the cellular pathways responsible for the presentation of these pathogen-derived epitopes on MHCII is absolutely vital.
It was long thought that a single, classical pathway is responsible for MHCII antigen presentation. In this pathway, internalized antigens are catabolized and loaded onto MHCII in late endosomal compartments. However, this pathway is likely inadequate for the presentation of both cytosolic antigens and antigens derived from proteins that are not carried within the pathogen, such as certain viral accessory proteins. Notably, a non-canonical, endogenous processing pathway has also been shown to play a significant role in the presentation of pathogen-derived epitopes.
Endogenous processing occurs when virally-derived antigens synthesized within infected APCs are proteolyzed and loaded onto MHCII via a complex network of intracellular pathways. This pathway is better suited for the presentation of cytosolic and newly synthesized viral antigens.
Current literature addressing the cellular pathways used by APCs to activate
CD4+ T cells in response to HIV-1 is sparse and conflicting. While some
HIV-1 epitopes can be presented from inactivated virus, two HIV-1 epitopes have been shown to be presented exclusively endogenously. Thus, the relative contributions of the classical and endogenous pathways in HIV-1 antigen presentation are not known. Additionally, our understanding of the cell types that act as APCs during HIV-1 infection is incomplete, as it is unknown if CD4+ T cells themselves act as APCs during an HIV-1 infection.
In this study, I will determine the ability of human dendritic cells, macrophages, and CD4+ T cells to present HIV-1 epitopes from infectious and inactivated virus. I will also elucidate the cellular pathways used by dendritic cells to present the two endogenously produced HIV-1 peptides referenced above. These studies will shed light on the cellular pathways used by dendritic cells and macrophages to process and present HIV-1 epitopes, and will interrogate the antigen presenting capabilities of CD4+ T cells during HIV infection. I anticipate that data obtained from this project will reveal key insights regarding HIV host-pathogen interplay and may inform rational vaccine design.

 

Yeqiao Zhou

Yeqiao Zhou

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: The Impact of Iron on Endolysosomal Function in the Retinal Pigment Epithelium

Advisor(s):

  • Robert Faryabi
  • Warren Pear

Rotations:

  • Warren Pear
  • Robert Faryabi
  • Golnaz Vahedi

Tammy Ying

Tammy Ying

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Rebecca Simmons

Rotations:

  • Peter Klein
  • Gerd Blobel
  • Rebecca Simmons
  • Roger Greenberg

During gestation, the fetus is highly susceptible to insults that will impact its later life. My thesis will elucidate the impact of intrauterine growth restriction…Read More

During gestation, the fetus is highly susceptible to insults that will impact its later life. My thesis will elucidate the impact of intrauterine growth restriction (IUGR), a common complication of pregnancy, on the immune system and the mechanism of how this transient insult can become deleterious in adulthood. Specifically, I will characterize the immune population in IUGR rats and determine the effects of IL-4 cytokine on newborns.

Daniel Xu

Daniel Xu

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Advisor(s):

  • Shelley Berger

Rotations:

  • Shelley Berger
  • Aimee Payne
  • Guo-Li Ming

Kevin Wiles

Kevin Wiles

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Determining how axon guidance molecules regulate tissue homeostasis in the Drosophila intestinal epithelium

Advisor(s):

  • Greg Bashaw

Rotations:

  • Greg Bashaw
  • Christopher Brown
  • Roberto Bonasio

Brandon Wenz

Brandon Wenz

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Christopher Brown

Rotations:

  • Christopher Brown
  • Raymond Soccio
  • Zhaolan Zhou

Bailey Warder

Bailey Warder

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Stephen Dinardo

Rotations:

  • Stephen Dinardo
  • Mary Mullins
  • Yana Kamberov

Aoi Wakabayashi

Aoi Wakabayashi

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Gerd Blobel

Rotations:

  • Gerd Blobel
  • Mitchell Lazar
  • Edward Morrisey

Increased levels of fetal hemoglobin (HbF) alleviates symptoms of beta hemoglobinopathies such as sickle cell disease. Therefore, it has been a long-standing interest in the…Read More

Increased levels of fetal hemoglobin (HbF) alleviates symptoms of beta hemoglobinopathies such as sickle cell disease. Therefore, it has been a long-standing interest in the hematopoiesis field to uncover underlying mechanisms of HbF regulation. From a screen, I have identified several hnRNPs that upregulate HbF expression when knocked down. Thus, I am interested in studying the role of these hnRNPs in the post-transcriptional regulation of HbF expression.

Gabriela Vida

Gabriela Vida

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Stephen Dinardo

Rotations:

  • Meera Sundaram
  • Greg Bashaw
  • Stephen Dinardo

Natalie Toothacre

Natalie Toothacre

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Montserrat Anguera

Rotations:

  • Montserrat Anguera
  • Marisa Bartolomei
  • Irfan Asangani

Sabine Schneider

Sabine Schneider

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2013

Project Title: Understanding the transcriptional regulation of enteric neuron subtype specification and differentiation

Advisor(s):

  • Robert Heuckeroth

Rotations:

  • Alice Chen-Plotkin
  • Robert Heuckeroth
  • Marcella Devoto

Alexandra Maldonado-Lopez

Alexandra Maldonado-Lopez

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Brian Capell

Rotations:

  • Brian Capell
  • Melike Lakadamyali
  • Fange Liu

Jennifer Luppino

Jennifer Luppino

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Project Title: Elucidating the role of chromatin architecture in the pathophysiology of Cornelia de Lange Syndrome

Advisor(s):

  • Eric Joyce

Rotations:

  • Alice Chen-Plotkin
  • Jennifer Phillips-Cremins
  • Eric Joyce

Jing Luan

Jing Luan

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2014

Advisor(s):

  • Gerd Blobel

Rotations:

  • Paul Lieberman
  • Kenneth Zaret
  • Gerd Blobel

My thesis topic involves dissecting the roles and mechanisms of transcriptional pausing, and understanding the dynamics and mechanisms of chromatin organization during erythropoiesis.

My thesis topic involves dissecting the roles and mechanisms of transcriptional pausing, and understanding the dynamics and mechanisms of chromatin organization during erythropoiesis.

Sheridan Littleton

Sheridan Littleton

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Struan Grant

Rotations:

  • Struan Grant
  • Ophir Shalem
  • Maja Bucan

Randi Isenhart

Randi Isenhart

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Eric Joyce

Rotations:

  • Maya Capelson
  • Eric Joyce
  • Andres Blanco

Guillaume Harmange

Guillaume Harmange

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Sydney Shaffer

Rotations:

  • Sydney Shaffer
  • Golnaz Vahedi
  • Lukasz Bugaj

Jailynn Harke

Jailynn Harke

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Probing the three-dimensional organization of enhancer-promoter communication

Advisor(s):

  • Douglas Epstein
  • Eric Joyce

Rotations:

  • Kenneth Zaret
  • Douglas Epstein
  • Eric Joyce

Matthew Haemmerle

Matthew Haemmerle

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Doris Stoffers

Rotations:

  • Doris Stoffers
  • Gerd Blobel
  • David Raizen

Clarissa Guzman-Roman

Clarissa Guzman-Roman

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Maya Capelson

Rotations:

  • Kavitha Sarma
  • Maya Capelson
  • Kenneth Zaret

Leela Dilley

Leela Dilley

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2013

Project Title: Identification of a molecular basis for the juvenile sleep state

Advisor(s):

  • Matthew Kayser

Rotations:

  • Amita Sehgal
  • Alice Chen-Plotkin
  • Matthew Kayser

Charles Danan

Charles Danan

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017

Rotations:

  • Andy Minn
  • Kathryn Hamilton

Jennifer Cohen

Jennifer Cohen

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014

Project Title: Apical extracellular matrix: Assembly and Function

Advisor(s):

  • Meera Sundaram

Rotations:

  • Mark Kahn
  • Benjamin Voight
  • Mary Mullins

Saisai Chen

Saisai Chen

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: The Role of PAQR8 in Breast Cancer Metastasis and Therapy Resistance

Advisor(s):

  • Lewis Chodosh

Rotations:

  • Mitchell Lazar
  • Lewis Chodosh
  • Mark Kahn

Zhendong Cao

Zhendong Cao

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Project Title: Roles of RNA-binding proteins and epigenetic regulators in acute myeloid leukemia

Advisor(s):

  • Junwei Shi

Rotations:

  • Jennifer Phillips-Cremins
  • Gerd Blobel
  • Junwei Shi

Christopher Cali

Christopher Cali

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2013

Advisor(s):

  • Edward Lee

Rotations:

  • Zhaolan Zhou
  • Edward Lee
  • Shelley Berger

My thesis work involves the study of a mutation in C9orf72 that is the most common cause of the neurodegenerative diseases Amyotrophic Lateral Sclerosis and…Read More

My thesis work involves the study of a mutation in C9orf72 that is the most common cause of the neurodegenerative diseases Amyotrophic Lateral Sclerosis and Frontal Temporal Degeneration.  We have developed a novel tool to introduce DNA methylation to a gene of interest, and my project utilizes this tool to generate cellular models of mutated C9orf72 in order to better understand the role of DNA methylation in the pathogenesis of these neurodegenerative diseases.

Blake Caldwell

Blake Caldwell

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Investigating the roles of active DNA demethylation pathways in epigenetic reprogramming

Advisor(s):

  • Marisa Bartolomei

Rotations:

  • Marisa Bartolomei
  • Thomas Jongens
  • Mary Mullins

Elizabeth Burton

Elizabeth Burton

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Struan Grant
  • Christopher Brown

Rotations:

  • Christopher Brown
  • Klaus Kaestner
  • Sarah Tishkoff

Niambi Brewer

Niambi Brewer

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014

Project Title: Gnas inactivation alters adipose tissue properties during progression to heterotopic ossification

Advisor(s):

  • Eileen Shore

Rotations:

  • Katherine Nathanson
  • Eileen Shore
  • Benjamin Voight

Marc Bornstein

Marc Bornstein

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017

Rotations:

  • Rahul Kohli
  • Zoltan Arany
  • Joe Baur

Zachary Beethem

Zachary Beethem

Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Montserrat Anguera

Rotations:

  • Montserrat Anguera
  • Mary Mullins
  • Foteini Mourkioti

Melissa Barton

Melissa Barton

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Erica Korb

Rotations:

  • Naiara Aquizu Lopez
  • Edward Lee
  • Erica Korb

Anthony Angueira

Anthony Angueira

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2014

Advisor(s):

  • Patrick Seale

Rotations:

  • Patrick Seale
  • Mitchell Lazar
  • Harry Ischiropoulos

I will utilize mouse genetics and metabolic assays to determine how BAT blood flow is regulated uponcold exposure.  In particular, I will focus on the…Read More

I will utilize mouse genetics and metabolic assays to determine how BAT blood flow is regulated uponcold exposure.  In particular, I will focus on the role of two novel targets in regulating BAT blood flow and how the thermogenic program regulates their expression. I hypothesize that these factors are required for BAT to increase blood flow and oxygen consumption following cold exposure. My thesis project will utilize classical mouse genetics and epigenomic techniques to determine the mechanisms regulating brown adipose blood flow.

 

Kimberly Veliz

Kimberly Veliz

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: Uncovering the role of CD38 in Acute Myeloid Leukemia

Advisor(s):

  • Saar Gill

Rotations:

  • Benjamin Prosser
  • Carl June
  • Saar Gill

Lucas Van Gorder

Lucas Van Gorder

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Harnessing PRPF31 as a Gene Therapy Target Utilizing an IPSC Model

Advisor(s):

  • Jean Bennett

Rotations:

  • Jean Bennett
  • Kar Muthumani
  • Valder Arruda

Sylvia Stankov

Sylvia Stankov

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: Functional Analysis of Triglyceride Regulator ApoA-V Using Naturally- Occurring Human Genetic Variants

Advisor(s):

  • Daniel Rader

Rotations:

  • Foteini Mourkioti
  • Daniel Rader
  • Kiran Musunuru

Zeyuan Edward Song

Zeyuan Edward Song

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: Combining IAP Inhibitors with CAR-T Cell Therapy to Treat Glioblastoma

Advisor(s):

  • Michael Milone

Rotations:

  • Youhai Chen
  • Michael Milone
  • Nicola Mason

Bryan Simpson

Bryan Simpson

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2014

Project Title: CRISPR-Cas9 Gene Editing Strategies of ATXN2 for the Treatment of Spinocerebellar Ataxia Type 2

Advisor(s):

  • Beverly Davidson

Rotations:

  • Jean Bennett
  • Matthew Weitzman
  • Beverly Davidson

Jesse Rodriguez

Jesse Rodriguez

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2012

Project Title: Re-directing cytomegalovirus specific chimeric antigen receptor T cells for glioblastoma multiforme cancer immunotherapy.

Advisor(s):

  • Carl June
  • Laura Johnson

Rotations:

  • Valder Arruda
  • Matthew Weitzman
  • Nicola Mason
  • Gregory Beatty
  • Carl June

Ryan Roark

Ryan Roark

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2015

Project Title: Ontogeny of HIV-1 V2 apex broadly neutralizing antibodies in SHIV-infected rhesus macaques

Advisor(s):

  • George Shaw

Rotations:

  • Luis Montaner
  • George Shaw
  • Erica Stone

Erin Reagan

Erin Reagan

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Patient-derived HCV-like particle expressed by a lipid nanoparticle-encapsulated nucleoside-modified mRNA vaccine for HCV prophylaxis via bNAb elicitation

Advisor(s):

  • Drew Weissman
  • Katharine Bar

Rotations:

  • David Weiner
  • Drew Weissman
  • Katharine Bar

Laura Ohl

Laura Ohl

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Naiara Aquizu Lopez

Rotations:

  • Naiara Aquizu Lopez
  • Kiran Musunuru
  • Beverly Davidson

Leon Morales

Leon Morales

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2014

Project Title: Assessing the Safety and Efficacy of a Gene Transfer Approach for Duchenne Muscular Dystrophy

Advisor(s):

  • Hansell Stedman
  • Jean Bennett

Rotations:

  • Valder Arruda
  • Hansell Stedman
  • Jean Bennett

Jacob Hoffman

Jacob Hoffman

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • James Wilson

Rotations:

  • Kiran Musunuru
  • Stefano Rivella
  • James Wilson

Maxwell Chappell

Maxwell Chappell

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Lentiviral Vectors as Therapeutic Options for the Treatment of Alpha-Thalassemia

Advisor(s):

  • Stefano Rivella

Rotations:

  • Valder Arruda
  • Stefano Rivella
  • John Wolfe

Rachel Blomberg

Rachel Blomberg

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2012

Project Title: Fibroblast activation protein and collagen remodeling in the intersection between obesity and breast cancer

Advisor(s):

  • Ellen Pure

Rotations:

  • James Wilson
  • Ellen Pure
  • Hildegund Ertl

I study intersections between obesity and the extracellular matrix (ECM), and how these interactions can affect the progression of breast cancer. In particular, I study…Read More

I study intersections between obesity and the extracellular matrix (ECM), and how these interactions can affect the progression of breast cancer. In particular, I study fibroblast activation protein, an ECM modulating protease that is upregulated in cancer and may impact adipocyte metabolism and tumor development. 

Kimberly Apodaca

Kimberly Apodaca

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Beatriz Carreno
  • Gerald Linette

Rotations:

  • Katharine Bar
  • Jan Melenhorst
  • Gerald Linette
  • Beatriz Carreno

Kevin Alicea-Torres

Kevin Alicea-Torres

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2014

Project Title: Role of IFNAR1 in the immune suppression by PMN-MDSCs in cancer

Advisor(s):

  • Dmitry Gabrilovich

Rotations:

  • Gregory Beatty
  • Celeste Simon
  • Dmitry Gabrilovich

Karen Wong

Karen Wong

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Determining the role of H3K9me2S10 phosphorylation in peripheral heterochromatin localization

Advisor(s):

  • Jonathan Epstein

Rotations:

  • Jonathan Epstein
  • Mark Kahn
  • Melike Lakadamyali

Ian Penkala

Ian Penkala

Developmental, Stem Cell and Regenerative Biology
Degree: VMD/PhD
Matriculation Year: 2014

Advisor(s):

  • Edward Morrisey

Rotations:

  • Ben Stanger
  • Edward Morrisey
  • Christopher Lengner

My thesis is focused on studying the developmental ontogeny and maturation process of alveolar type one cells in the lung.

My thesis is focused on studying the developmental ontogeny and maturation process of alveolar type one cells in the lung.

Sarshan Pather

Sarshan Pather

Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2016

Advisor(s):

  • Hongjun Song

Rotations:

  • Rajan Jain
  • Hongjun Song
  • Guo-Li Ming
  • D. Kacy Cullen

Christopher Pai

Christopher Pai

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Robert Heuckeroth

Rotations:

  • Montserrat Anguera
  • Robert Heuckeroth
  • Mia Levine

I'm studying the role of microRNAs in the development of the enteric nervous system.

I'm studying the role of microRNAs in the development of the enteric nervous system.

Somdutta Mukherjee

Somdutta Mukherjee

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Project Title: Investigating the Role of TBX3 in Human Endoderm Development

Advisor(s):

  • Paul Gadue

Rotations:

  • Paul Gadue
  • John Murray
  • Warren Pear

Nicolette Johnson

Nicolette Johnson

Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2015

Advisor(s):

  • Christopher Lengner

Rotations:

  • Thomas Leung
  • Katalin Susztak
  • Rebecca Wells

Allison Jamieson-Lucy

Allison Jamieson-Lucy

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2012

Advisor(s):

  • Mary Mullins

Rotations:

  • Erfei Bi
  • Mary Mullins
  • Edward Morrisey

The Balbiani body (Bb) is a transient aggregate found within the oocytes of many species, conserved form insects to humans. It shares structural similarities with…Read More

The Balbiani body (Bb) is a transient aggregate found within the oocytes of many species, conserved form insects to humans. It shares structural similarities with amyloid plaques that cause degenerative disease. Understanding the Bb will provide insight how amyloid networks form and disassemble in a non-disease context, but few components of the Bb have been characterized. I am using proteomics, live imaging and gene editing to identify novel components of the Bb and discover their function.

Elizabeth Howell

Elizabeth Howell

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Identifying necessary chromatin states and targets for hemogenic specification and reprogramming by the transcription factor Runx1

Advisor(s):

  • Nancy Speck

Rotations:

  • Peter Klein
  • Nancy Speck
  • Klaus Kaestner

Christopher Greer

Christopher Greer

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Comparative phylogenetics of the dystrophin associated protein complex protein families and implications for Adeno-associated virus (AAV)-mediated gene therapy in Duchenne muscular dystrophy.

Advisor(s):

  • Hansell Stedman

Rotations:

  • Jonathan Epstein
  • Foteini Mourkioti
  • Jason Burdick
  • Hansell Stedman

Hannah Greenfeld

Hannah Greenfeld

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Interpretation of the BMP morphogen gradient patterning the dorsal-ventral axis of the zebrafish embryo

Advisor(s):

  • Mary Mullins

Rotations:

  • Patrick Seale
  • Mary Mullins
  • Greg Bashaw

A gradient of BMP signaling activity patterns the dorsoventral embryonic axis of all vertebrates. My project seeks the mechanism by which cells interpret different levels…Read More

A gradient of BMP signaling activity patterns the dorsoventral embryonic axis of all vertebrates. My project seeks the mechanism by which cells interpret different levels of BMP signaling to specify different ventral cell fates.

Elizabeth Gallagher

Elizabeth Gallagher

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Erika Holzbaur

Rotations:

  • Erika Holzbaur
  • Greg Bashaw
  • Matthew Good

Ioana Soaita

Ioana Soaita

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Zoltan Arany

Rotations:

  • Elizabeth Grice
  • Zoltan Arany
  • Raymond Soccio

Benjamin Philipson

Benjamin Philipson

Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2013

Project Title: From bench to bedside and back again: CAR T cell signaling and survival

Advisor(s):

  • Michael Milone
  • Steven Albelda

Rotations:

  • Kevin Foskett
  • Taku Kambayashi
  • Michael Milone

Jessica Phan

Jessica Phan

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Edward Lee

Rotations:

  • Kelly Jordan-Sciutto
  • Edward Lee
  • Robert Kalb

Riley Payne

Riley Payne

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014

Project Title: The Molecular Basis for Rapid Ca2+ Transport Across the Inner Mitochondrial Membrane

Advisor(s):

  • Kevin Foskett

Rotations:

  • Kevin Foskett
  • Carol Deutsch
  • Michael Ostap

Michael Neinast

Michael Neinast

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • Zoltan Arany

Rotations:

  • Benjamin Prosser
  • Zoltan Arany
  • Joe Baur

I am studying branched-chain amino acid (BCAA) metabolism and how it changes with obesity.  BCAAs worsen insulin resistance but the mechanism is controversial.  Many proposed mechanisms hinge on changes…Read More

I am studying branched-chain amino acid (BCAA) metabolism and how it changes with obesity.  BCAAs worsen insulin resistance but the mechanism is controversial.  Many proposed mechanisms hinge on changes in BCAA metabolism in specific tissues, but those changes are unclear.  By measuring BCAA metabolism in vivo, I have found that BCAA metabolism increases in skeletal muscle of obese mice.  I am now testing the hypothesis that increased muscle BCAA metabolism contributes to insulin resistance.

Danielle Murashige

Danielle Murashige

Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2014

Advisor(s):

  • Zoltan Arany

Rotations:

  • Zoltan Arany
  • Hao Wu
  • Adam Resnick

Quentin McAfee

Quentin McAfee

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Zoltan Arany

Rotations:

  • Michael Marks
  • Benjamin Prosser
  • Zoltan Arany

Yaoyu Gong

Yaoyu Gong

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Project Title: Enhancing antitumor cytotoxicity of natural killer cells by increasing their intracellular pH

Advisor(s):

  • Chi Dang

Rotations:

  • Chi Dang
  • Mitchell Lazar
  • Celeste Simon

Clark Fritsch

Clark Fritsch

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Yale Goldman

Rotations:

  • Marc Vermulst
  • Rugang Zhang
  • Edward Lee
  • Ronen Marmorstein

Emily Flam

Emily Flam

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Zoltan Arany

Rotations:

  • Zoltan Arany
  • Benjamin Prosser
  • Kenneth Margulies

Emily Fernandez Garcia

Emily Fernandez Garcia

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014

Project Title: Targeting Calcium Signaling from the Endoplasmic Reticulum to Mitochondria for the Development of New Chemotherapies

Advisor(s):

  • Kevin Foskett

Rotations:

  • Kevin Foskett
  • Erika Holzbaur
  • Robert Kalb

 As a dissertation student my thesis project aims to understand how genetic and pharmacological inhibition of calcium influx into mitochondria, as well as inhibition of…Read More

 As a dissertation student my thesis project aims to understand how genetic and pharmacological inhibition of calcium influx into mitochondria, as well as inhibition of calcium transfer from the endoplasmic reticulum (ER) to mitochondria affects the survival of cancer cells in vitro and in vivo. Cancer is characterized by accelerated growth and division of unhealthy cells. While mitochondria are the main organelles that supply the energetic needs of cells through oxidative phosphorylation, the most prominent feature of cancer cells is a remodeled cell metabolism based on constitutive aerobic glycolysis. It is then reasonably assumed that the biological function of mitochondria as the “powerhouse of the cell” is diminished in cancer cells.
     On the other hand, the unexpected finding from our lab published by Cardenas et al., (2016), revealed that constitutive influx of calcium into mitochondria is indispensable for survival of cancer cells. Therefore, I propose that calcium signaling from the ER to mitochondria, as well as calcium influx to mitochondria can be independently targeted for the development of novel chemotherapeutics to selectively damage and kill cancer cells. While the Foskett lab is recognized by the international scientific community as a significant contributor in many research areas, such as calcium signaling, the development of my project in cancer biology will enrich the expertise of the lab. Furthermore, I expect that the knowledge gained from my research will be employed to optimize and increase current chemotherapies.

 

Lisa Cucolo

Lisa Cucolo

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2013

Project Title: Tumor RIPK1 Signaling Mediates Intrinsic and Extrinsic Mechanisms of Resistance to Immune Checkpoint Blockade Therapy

Advisor(s):

  • Andy Minn

Rotations:

  • Kathryn Wellen
  • Mitchell Lazar
  • Andy Minn
  • Dwight Gilliland

Allison Cote

Allison Cote

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2012

Advisor(s):

  • Arjun Raj

Rotations:

  • Rebecca Wells
  • Janis Burkhardt
  • Arjun Raj

Expansion microscopy is a technique that involves the use of a swellable polymer network to physically expand the specimen of interest and physically separate points…Read More

Expansion microscopy is a technique that involves the use of a swellable polymer network to physically expand the specimen of interest and physically separate points that we were previously unable to resolve. This technique, in combination with single molecule RNA FISH and immunofluorescence, has allowed us to observe the colocalization of individual endogenous RNAs with proteins involved in transcription and RNA processing at the site of nascent transcription.

 

Stephen Coscia

Stephen Coscia

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Project Title: A mechanistic investigation into F-actin assembly on mitochondria as a wave

Advisor(s):

  • Erika Holzbaur

Rotations:

  • Erika Holzbaur
  • Michael Ostap
  • James Shorter

Jessica Chotiner

Jessica Chotiner

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Project Title: Cyclin B3 is an essential factor in female fertility and embryonic development

Advisor(s):

  • Jeremy Wang

Rotations:

  • Jeremy Wang
  • Yana Kamberov
  • Marisa Bartolomei

Salina Yuan

Salina Yuan

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2013

Project Title: Epigenetic mechanisms regulating epithelial plasticity in pancreatic ductal adenocarcinoma

Advisor(s):

  • Ben Stanger

Rotations:

  • Ben Stanger
  • Kathryn Wellen
  • Donita Brady

Sixiang Yu

Sixiang Yu

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • Xiaolu Yang

Rotations:

  • Shelley Berger
  • Xiaolu Yang
  • Gerd Blobel

Darwin Ye

Darwin Ye

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Pattern recognition receptor signaling in immune checkpoint blockade resistance

Advisor(s):

  • Andy Minn

Rotations:

  • Andy Minn
  • Junwei Shi
  • Shelley Berger

Fangxue (Yumi) Yan

Fangxue (Yumi) Yan

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: The role of Epigenetic Regulators in Restricting LSD1i-Mediated Differentiation in Acute Myeloid Leukemia

Advisor(s):

  • Andres Blanco

Rotations:

  • Ben Stanger
  • David Feldser
  • Andres Blanco

Caiyue Xu

Caiyue Xu

Cancer Biology
Degree: PhD
Matriculation Year: 2013

Project Title: Characterization of novel nuclear substrates of mammalian autophagy pathway in cellular senescence and aging

Advisor(s):

  • Shelley Berger

Rotations:

  • Shelley Berger
  • Anil Rustgi
  • Meenhard Herlyn

David Walter

David Walter

Cancer Biology
Degree: PhD
Matriculation Year: 2013

Project Title: Elucidating the tumor suppressive functions of Rb and Setd2 in lung adenocarcinoma

Advisor(s):

  • David Feldser

Rotations:

  • David Feldser
  • James Riley
  • Xiaolu Yang

Tiffany Tsang

Tiffany Tsang

Cancer Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Paradoxical YAP activation as an emergent limitation to Cu chelation therapy in BRAFV600E-driven melanoma

Advisor(s):

  • Donita Brady

Rotations:

  • Donita Brady
  • Kathryn Wellen
  • Constantinos Koumenis

Jinyang Li

Jinyang Li

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Investigating tumor cell-intrinsic factors regulating immune infiltration in pancreatic cancer

Advisor(s):

  • Ben Stanger

Rotations:

  • Ben Stanger
  • Lewis Chodosh
  • Kathryn Wellen

Jesse Lee

Jesse Lee

Cancer Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Gregory Beatty

Rotations:

  • John Maris
  • Saar Gill
  • Gregory Beatty

In Young Lee

In Young Lee

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Understanding and Overcoming Melanoma Resistance to GPCR-based Therapy

Advisor(s):

  • Todd Ridky

Rotations:

  • David Feldser
  • Todd Ridky
  • Gerald Linette

Avery Lee

Avery Lee

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating the Roles of Activation-Induced Cytidine Deaminase in theMalignant Progression of Chronic Lymphocytic Leukemia

Advisor(s):

  • Andrew Hu

Rotations:

  • Tzipora Sarah Karin Eisinger
  • Andrew Hu
  • Oliver Garden

Linh Le

Linh Le

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Investigating the mechanisms underlying melanosome biogenesis and maturation

Advisor(s):

  • Michael Marks

Rotations:

  • Andrei Thomas-Tikhonenko
  • Rugang Zhang
  • Michael Marks
  • Patrick Viatour

Claudia Lanauze

Claudia Lanauze

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • Andrei Thomas-Tikhonenko

Rotations:

  • Andrei Thomas-Tikhonenko
  • Nancy Speck
  • Xianxin Hua

Piotr Kopinski

Piotr Kopinski

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2011

Project Title: Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy

Advisor(s):

  • Douglas Wallace

Rotations:

  • Jean Bennett
  • Douglas Wallace
  • Shelley Berger

Priya Khurana

Priya Khurana

Cancer Biology
Degree: PhD
Matriculation Year: 2015

Project Title: Investigating the immunometabolism and anti-tumor properties of invariant natural killer T (iNKT) cells in neuroblastoma

Advisor(s):

  • Hamid Bassiri

Rotations:

  • Roger Greenberg
  • Maureen Murphy
  • Hamid Bassiri

Sanika Khare

Sanika Khare

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • Celeste Simon

Rotations:

  • Warren Pear
  • Mitchell Lazar
  • Celeste Simon

My thesis topic is investigating the role of urea cycle enzymes in clear cell renal cell carcinoma (ccRCC) progression. We observe reduction in the levels…Read More

My thesis topic is investigating the role of urea cycle enzymes in clear cell renal cell carcinoma (ccRCC) progression. We observe reduction in the levels of urea cycle enzymes in ccRCC tumors when compared to the normal kidney. Re-expression of these enzymes slows cancer cell growth while loss promotes proliferation.  Based on these data we hypothesize that urea cycle enzymes may act as potential tumor suppressors in ccRCC.

Kanika Jain

Kanika Jain

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Margaret Chou

Rotations:

  • Andy Minn
  • Saar Gill
  • Dmitry Gabrilovich
  • Gregory Beatty

Luke Izzo

Luke Izzo

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating the role of ACLY and acetyl-CoA metabolism in hepatocellular carcinoma

Advisor(s):

  • Kathryn Wellen

Rotations:

  • Kathryn Wellen
  • Wei Tong
  • Martin Carroll

Yinghui (Jane) Huang

Yinghui (Jane) Huang

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Role of HMG-box transcription factor TOX in maintaining CD8 T cell exhaustion

Advisor(s):

  • John Wherry

Rotations:

  • Dmitry Gabrilovich
  • Jorge Henao-Mejia
  • John Wherry

Rebecca Glynn

Rebecca Glynn

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Defining the Mechanism and Function of DNA Double Strand Break Induced Inhibition of V(D)J Recombination

Advisor(s):

  • Craig Bassing

Rotations:

  • John Maris
  • Ronny Drapkin
  • Craig Bassing

Ian Folkert

Ian Folkert

Cancer Biology
Degree: PhD
Matriculation Year: 2016

Project Title: The Role of the Endothelin B Receptor in Macrophage Function

Advisor(s):

  • Malay Haldar

Rotations:

  • Ben Stanger
  • Anil Rustgi
  • Malay Haldar

Jorida Coku

Jorida Coku

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Elucidating mechanisms of cancer therapy resistance due to alterations in endoplasmic reticulum-mitochondria contact sites

Advisor(s):

  • Michael Hogarty

Rotations:

  • Vera Krymskaya
  • Michael Hogarty
  • Rugang Zhang

Zeyu Chen

Zeyu Chen

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Dissecting transcriptional network during CD8+ T cell response

Advisor(s):

  • John Wherry

Rotations:

  • David Feldser
  • John Wherry
  • Mitchell Lazar


 


 

Sydney Campbell

Sydney Campbell

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • Kathryn Wellen

Rotations:

  • Kathryn Wellen
  • Celeste Simon
  • Shelley Berger

My thesis is focused on understanding the functional impacts of changes in flux through the hexosamine biosynthesis pathway in pancreatic cancer.
 

My thesis is focused on understanding the functional impacts of changes in flux through the hexosamine biosynthesis pathway in pancreatic cancer.
 

Rebekah Brooks

Rebekah Brooks

Cancer Biology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Chi Dang

Rotations:

  • Donita Brady
  • Celeste Simon
  • Chi Dang

I am currently working on determining the function of a previously uncharacterized circadian oscillating long noncoding RNA (lncRNA) that may modulate the degradation of an…Read More

I am currently working on determining the function of a previously uncharacterized circadian oscillating long noncoding RNA (lncRNA) that may modulate the degradation of an important chromatin modifying complex. In addition to normal physiology, this interaction may also play a role in clear cell renal carcinoma (ccRCC) progression.

Brian Benz

Brian Benz

Cancer Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Lewis Chodosh

Rotations:

  • Wei Tong
  • Todd Ridky
  • Lewis Chodosh

Vivek Behera

Vivek Behera

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2011

Project Title: MINING THE SPATIAL AND TEMPORAL CONTEXT BY WHICH TRANSCRIPTION FACTORS OCCUPY CHROMATIN

Advisor(s):

  • Gerd Blobel

Rotations:

  • Gerd Blobel
  • Kristen Lynch
  • Roger Greenberg

Keren Adler

Keren Adler

Cancer Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • David Feldser

Rotations:

  • Sandra Ryeom
  • Ben Stanger
  • David Feldser

Jonuelle Acosta

Jonuelle Acosta

Cancer Biology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • David Feldser

Rotations:

  • David Feldser
  • Kristen Lynch
  • Donita Brady

The tumor suppressor p53 can transactivate genes that mediate cytostatic and cytotoxic anti-tumor responses in a context-dependent manner. However, it is not known exactly how…Read More

The tumor suppressor p53 can transactivate genes that mediate cytostatic and cytotoxic anti-tumor responses in a context-dependent manner. However, it is not known exactly how p53 mediates its pleiotropic effects. My thesis project incorporates the usage of established mouse models of lung cancer and cancer cell lines to dissect the mechanisms behind the pleiotropic tumor suppressive programs mediated by p53.

Jayme Nordin

Jayme Nordin

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Zhaolan Zhou

Catriana Nations

Catriana Nations

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Paul Gadue

Kelly Martins

Kelly Martins

Gene Therapy and Vaccines
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

  • James Wilson

Rotations:

  • Kiran Musunuru
  • James Wilson

Claudia Lovell

Claudia Lovell

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

  • Kathryn Wellen

Jingxin (Jessica) Li

Jingxin (Jessica) Li

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018

Advisor(s):

  • Arjun Raj

Rotations:

  • Mitchell Lazar
  • Arjun Raj

Elisabeth Lemmon

Elisabeth Lemmon

Developmental, Stem Cell, and Regenerative Biology
Degree: VMD/PhD
Matriculation Year: 2018

Rotations:

  • Robert Mauck

Amanda Lee

Amanda Lee

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Andy Minn
  • Marco Ruella

Andrew Katznelson

Andrew Katznelson

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Gerd Blobel

Nathan Katz

Nathan Katz

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

  • Daniel Rader

Yanqing (Christine) Jiang

Yanqing (Christine) Jiang

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Celeste Simon

Michaela Helble

Michaela Helble

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Daniel Powell

Nicholas Grams

Nicholas Grams

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Dieter Schifferli
  • Matthew Weitzman

Brian Goldspiel

Brian Goldspiel

Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

  • Carolina Lopez

Amy Gladstein

Amy Gladstein

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Brian Capell

Annabel Ferguson

Annabel Ferguson

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Sara Cherry

Katherine Doerig

Katherine Doerig

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • David Feldser

Perry Demsko

Perry Demsko

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Michael Milone
  • Saar Gill

Patricia Colosi

Patricia Colosi

Cell Biology, Physiology, and Metabolism
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Meera Sundaram

Ian Cohn

Ian Cohn

Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

  • Scott Hensley

Roderick Brathwaite

Roderick Brathwaite

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Lewis Chodosh

Charles Bond

Charles Bond

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Melike Lakadamyali

Nicholas Bolden

Nicholas Bolden

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Paula Oliver

Ryan Boe

Ryan Boe

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

  • Arjun Raj

Rotations:

  • Jennifer Phillips-Cremins
  • Arjun Raj

Nicholas Aboreden

Nicholas Aboreden

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Junwei Shi

Jenna Zhang

Jenna Zhang

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

  • Sunny Shin

Rotations:

  • Sunny Shin
  • Joseph Zackular

Frances Taschuk

Frances Taschuk

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2013

Project Title: Antiviral activities of DEAD-box RNA helicases

Advisor(s):

  • Sara Cherry

Rotations:

  • Sara Cherry
  • Sunny Shin
  • Matthew Weitzman

Alice Sukhina

Alice Sukhina

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Will Bailis

Rotations:

  • Christopher Hunter
  • Warren Pear
  • Will Bailis

Ariel Shepley-McTaggart

Ariel Shepley-McTaggart

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Project Title: The Ups and Downs of Host Regulation of Ebola Hemorrhagic Fever Virus Egress

Advisor(s):

  • Ronald Harty

Rotations:

  • Beatrice Hahn
  • Matthew Weitzman
  • Ronald Harty

Elisha Segrist

Elisha Segrist

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Project Title: Investigating the Role of STING during enteric RNA virus infection in Drosophila

Advisor(s):

  • Sara Cherry

Rotations:

  • Sara Cherry
  • Harvey Friedman
  • Laurence Eisenlohr

Prioty Sarwar

Prioty Sarwar

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Paul Planet

Rotations:

  • Paul Planet
  • Dustin Brisson

Ronnie Russell

Ronnie Russell

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • Beatrice Hahn

Rotations:

  • Una O’Doherty
  • George Shaw
  • Beatrice Hahn

My thesis research is focused on the role of type 1 interferon on the evolution of HIV-1. This includes studying the ways in which SIVcpz…Read More

My thesis research is focused on the role of type 1 interferon on the evolution of HIV-1. This includes studying the ways in which SIVcpz adapted to the human interferon response following cross-species transmission, as well as studying the interferon resistance over time within HIV-1 infected individuals.

David Renner

David Renner

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Susan Weiss

Rotations:

  • Matthew Weitzman
  • Susan Weiss
  • Kristen Lynch

Tzvi Pollock

Tzvi Pollock

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Project Title: Determining the Mechanism of TNF-Mediated Defense Against Intracellular Legionella pneumophila Infection

Advisor(s):

  • Sunny Shin

Rotations:

  • Phillip Scott
  • Michael Povelones
  • Sunny Shin

Alexandra Perry

Alexandra Perry

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Joseph St Geme

Rotations:

  • Joseph St Geme
  • Kimberly Gallagher
  • Mechthild Pohlschroder

Elise Peauroi

Elise Peauroi

Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2015

Project Title: Investigating the innate immune antagonistic effects of the multifunctional C15 protein of Ectromelia virus

Advisor(s):

  • Laurence Eisenlohr

Rotations:

  • Matthew Weitzman
  • Scott Hensley
  • Laurence Eisenlohr

Son Nguyen

Son Nguyen

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • James Hoxie
  • Michael Betts

Rotations:

  • James Hoxie
  • Michael Betts
  • Laura Su

Kalyani Nambiar

Kalyani Nambiar

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2014

Project Title: Isolation and Characterization of Novel Adeno-associated Viruses from Mammalian Hosts; Development of Vectors for Gene Therapy

Advisor(s):

  • James Wilson

Rotations:

  • Luis Montaner
  • James Wilson
  • Matthew Weitzman

Daniel Morris

Daniel Morris

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • George Shaw

Rotations:

  • George Shaw
  • Katharine Bar
  • Michael Betts

Nina Montoya

Nina Montoya

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Defining capsule and exopolysaccharide-independent complement resistance factors in Kingella kingae

Advisor(s):

  • Joseph St Geme

Rotations:

  • Elizabeth White
  • Laurence Eisenlohr
  • Joseph St Geme

Rina Matsuda

Rina Matsuda

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Role of Yersinia pseudotuberculosis virulence in granuloma formation during intestinal infection

Advisor(s):

  • Igor Brodsky

Rotations:

  • Igor Brodsky
  • Boris Striepen
  • Michael Abt

Kaitlin Marquis

Kaitlin Marquis

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Frederic Bushman

Rotations:

  • Susan Weiss
  • Sara Cherry
  • Frederic Bushman

Tomaz Manzoni

Tomaz Manzoni

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Project Title: Identifying reservoir cells of persistently infecting Sendai virus in vivo

Advisor(s):

  • Paul Bates

Rotations:

  • Carolina Lopez
  • Laurence Eisenlohr
  • Paul Bates

Natasha Lopes Fischer

Natasha Lopes Fischer

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Project Title: Evasion of Human Innate Immunity by Coxiella burnetii

Advisor(s):

  • Sunny Shin

Rotations:

  • Michael Betts
  • Sunny Shin
  • Paul Planet

Valerie Linck

Valerie Linck

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Ronald Collman

Rotations:

  • Ronald Harty
  • Jianxin You
  • Ronald Collman

Nathan Krump

Nathan Krump

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Project Title: Dissecting the Immune Response to Merkel Cell Polyomavirus Infection

Advisor(s):

  • Jianxin You

Rotations:

  • Matthew Weitzman
  • Jianxin You
  • Igor Brodsky

Christin Herrmann

Christin Herrmann

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2013

Project Title: Adenovirus strategies for altering the cellular environment in favor of infection

Advisor(s):

  • Matthew Weitzman

Rotations:

  • Una O’Doherty
  • Scott Hensley
  • Sara Cherry
  • Matthew Weitzman

Joshua Hatterschide

Joshua Hatterschide

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: The role of PTPN14 inactivation by HPV E7 in the differentiation-dependent HPV life cycle

Advisor(s):

  • Elizabeth White

Rotations:

  • Carolina Lopez
  • Elizabeth White
  • Susan Weiss

Christopher Gu

Christopher Gu

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Frederic Bushman

Rotations:

  • Frederic Bushman
  • Elizabeth Grice
  • Scott Hensley

Emmanuelle Genoyer

Emmanuelle Genoyer

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • Carolina Lopez

Rotations:

  • Jianxin You
  • Carolina Lopez
  • Susan Weiss

Defective viral genomes of paramyxoviruses, the initial triggers of antiviral immunity during infection, are localized discretely from full-length viral genomes in the context of infection.…Read More

Defective viral genomes of paramyxoviruses, the initial triggers of antiviral immunity during infection, are localized discretely from full-length viral genomes in the context of infection.  I am investigating the mechanisms of viral genome localization within a cell and the consequences that these discrete localizations have on innate immune induction.

Devin Fisher

Devin Fisher

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Carolina Lopez

Rotations:

  • Hao Shen
  • David Weiner
  • Carolina Lopez

My project is examining the mechanism of recognition of defective viral genomes (DVGs) during paramyxovirus infections in vivo. Additionally, I will be examining the mechanism…Read More

My project is examining the mechanism of recognition of defective viral genomes (DVGs) during paramyxovirus infections in vivo. Additionally, I will be examining the mechanism of action of DVG-derived oligonucleotides as vaccine adjuvants to understand how these adjuvants are able to induce type-I immune responses. All in all I am examining how immune responses capable of clearing intracellular pathogens are initiated.

 

Natania Field

Natania Field

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2012

Project Title: ITCH AND CULLIN 5 ATTENUATE TYPE 2 INFLAMMATION THROUGH DISTINCT MECHANISMS

Advisor(s):

  • Paula Oliver

Rotations:

  • Warren Pear
  • Paula Oliver
  • Janis Burkhardt

Grant Eilers

Grant Eilers

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2014

Project Title: Structural Studies of Antiretroviral Drugs Targeting HIV Integrase

Advisor(s):

  • Frederic Bushman
  • Gregory Van Duyne

Rotations:

  • Frederic Bushman
  • Katharine Bar
  • Gregory Van Duyne

I will be studying HIV integrase. Multimeric forms of integrase are the target of two classes of antiretroviral therapy, the strand transfer inhibitors and the…Read More

I will be studying HIV integrase. Multimeric forms of integrase are the target of two classes of antiretroviral therapy, the strand transfer inhibitors and the allosteric inhibitors of integrase. My thesis topic is to characterize the multimeric forms of integrase that are relevant for understanding mechanisms of action and resistance to antiretroviral therapy.

 

Marisa Egan

Marisa Egan

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Sunny Shin

Rotations:

  • Jun Zhu
  • Sunny Shin
  • Mark Goulian

Amy Davis

Amy Davis

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2013

Project Title: The effect of early life exposure on influenza antibody repertoire and subsequent consequences for viral evolution

Advisor(s):

  • Scott Hensley

Rotations:

  • Rahul Kohli
  • Scott Hensley
  • Frederic Bushman

My thesis, broadly speaking, studies host-pathogen interactions that occur during influenza infection and vaccination.  One aspect of this work focuses on studying the evolution of…Read More

My thesis, broadly speaking, studies host-pathogen interactions that occur during influenza infection and vaccination.  One aspect of this work focuses on studying the evolution of influenza in response to the selective pressure of different types of immune responses. Another aspect focuses on differences between how previously naïve populations respond to vaccination versus infection. 

Emily Cribas

Emily Cribas

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Michael Abt

Rotations:

  • Michael Abt
  • Gary Wu
  • Jun Zhu

Courtney Comar

Courtney Comar

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Susan Weiss

Rotations:

  • Paul Bates
  • Susan Weiss
  • Carolina Lopez

My thesis project will focus on Middle East respiratory syndrome coronavirus (MERS-CoV) interactions with the human host innate immune system. MERS-CoV encodes a small, dsRNA…Read More

My thesis project will focus on Middle East respiratory syndrome coronavirus (MERS-CoV) interactions with the human host innate immune system. MERS-CoV encodes a small, dsRNA binding protein, NS4a. I hypothesize that the role of NS4a during infection is to antagonize multiple antiviral dsRNA-induced pathways in the host cell.
 

Clare Cimperman

Clare Cimperman

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Elizabeth White

Pankhuri Singhal

Pankhuri Singhal

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Improved prediction modeling of complex genetic disease with multiomic data integration using knowledge-based variable selection

Advisor(s):

  • Marylyn Ritchie

Rotations:

  • Christopher Brown
  • Rui Feng
  • Marylyn Ritchie

Stephanie Sansbury

Stephanie Sansbury

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Ophir Shalem

Rotations:

  • Sarah Tishkoff
  • Golnaz Vahedi
  • Ophir Shalem

Alexander Sakers

Alexander Sakers

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2013

Project Title: Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

Advisor(s):

  • Patrick Seale

Rotations:

  • Daniel Rader
  • Mitchell Lazar
  • Patrick Seale

Sean Ryan

Sean Ryan

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014

Advisor(s):

  • Kelly Jordan-Sciutto
  • Stewart Anderson

Rotations:

  • Nancy Bonini
  • Stewart Anderson
  • Peter Klein

I am studying the role of the complement cascade and sex differences in HIV-mediated neurotoxicity, which leads to development of HIV-Associated Neurocognitive Disorders. I am…Read More

I am studying the role of the complement cascade and sex differences in HIV-mediated neurotoxicity, which leads to development of HIV-Associated Neurocognitive Disorders. I am utilizing several model systems including: primary rat cortical cultures, HiPSC –derived neuron-glia co-cultures, and post mortem, human brain tissue to determine if complement can cause neurotoxicity, and if complement or other inflammatory molecules are expressed differently between males and females when HIV-infected

Jonathan Rumley

Jonathan Rumley

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2013

Project Title: Regulation of anterior genes in the C. elegans embryo

Advisor(s):

  • John Murray

Rotations:

  • Dwight Stambolian
  • Maya Capelson
  • John Murray

Caleb Radens

Caleb Radens

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Alternative Splicing Variations in T cells and B-ALL

Advisor(s):

  • Yoseph Barash
  • Kristen Lynch

Rotations:

  • Christopher Brown
  • Benjamin Voight
  • Kristen Lynch
  • Yoseph Barash

Wenchao Qian

Wenchao Qian

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Regulation of Genome Activation and Contribution of a Spatial Pattern of Zygotic Transcription in Vertebrate Early Embryo Development

Advisor(s):

  • Matthew Good

Rotations:

  • Hao Wu
  • Kenneth Zaret
  • Gerd Blobel
  • Melike Lakadamyali

Sai Phyo

Sai Phyo

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2015

Advisor(s):

  • Benjamin Prosser

Rotations:

  • Roger Greenberg
  • Kenneth Zaret
  • Gerd Blobel
  • Jennifer Phillips-Cremins

Ana Petracovici

Ana Petracovici

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Project Title: Dissecting the roles of Polycomb Repressive 2 accessory subunits during early developmental transitions

Advisor(s):

  • Roberto Bonasio

Rotations:

  • Hao Wu
  • Roberto Bonasio
  • Alessandro Gardini

Felicia Peng

Felicia Peng

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • John Murray

Rotations:

  • John Murray
  • Maya Capelson
  • Doris Wagner

Daniel Park

Daniel Park

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Investigating the role of chromosome architecture in the pathophysiology of Cornelia de Lange Syndrome

Advisor(s):

  • Eric Joyce

Rotations:

  • Jennifer Phillips-Cremins
  • Eric Joyce
  • Edward Lee

Gina Pacella

Gina Pacella

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Brian Capell

Rotations:

  • Brian Capell
  • Golnaz Vahedi
  • Elizabeth Heller

Alexis Oguh

Alexis Oguh

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Doris Stoffers

Rotations:

  • Zhaolan Zhou
  • Doris Stoffers
  • Ophir Shalem

Sarah Offley

Sarah Offley

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Alessandro Gardini

Rotations:

  • Alessandro Gardini
  • John Murray
  • Shawn Little

Emily O'Driscoll

Emily O'Driscoll

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating Proteolytic Cleavage Events Using Genome-Wide CRISPR/Cas9 Knockout Screens

Advisor(s):

  • Ophir Shalem

Rotations:

  • Ophir Shalem
  • Nancy Bonini
  • Edward Lee

Mailyn Nishiguchi

Mailyn Nishiguchi

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Edward Behrens

Rotations:

  • Todd Ridky
  • Panteleimon Rompolas
  • Thomas Leung

Ricardo Linares Saldana

Ricardo Linares Saldana

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2014

Advisor(s):

  • Rajan Jain
  • Jonathan Epstein

Rotations:

  • Edward Lee
  • Rajan Jain
  • Ben Black

My work focuses on elucidating mechanisms by which multipotent cardiac progenitors make cell fate decisions during cardiac specification. More specifically, I am defining the role…Read More

My work focuses on elucidating mechanisms by which multipotent cardiac progenitors make cell fate decisions during cardiac specification. More specifically, I am defining the role of the cardiac factor Hopx and its interplay with the spatial organization of chromatin in committing progenitors to the cardiomyogenic fate.

Marianne Kramer

Marianne Kramer

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014

Project Title: Understanding the role of post-transcriptional gene regulation and long non-coding RNAs during plant stress and development

Advisor(s):

  • Brian Gregory

Rotations:

  • Montserrat Anguera
  • Brian Gregory
  • Jeremy Wilusz

Ayano Kondo

Ayano Kondo

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Project Title: Role of Foxl1+ mesenchymal cell-derived Wnt5a during intestinal development

Advisor(s):

  • Klaus Kaestner

Rotations:

  • Zachary Schug
  • Klaus Kaestner
  • Katalin Susztak

Karun Kiani

Karun Kiani

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Inducing transcriptional reprogramming with targeted chemotherapy

Advisor(s):

  • Arjun Raj

Rotations:

  • Erika Holzbaur
  • Arjun Raj
  • Golnaz Vahedi

Ashley Karnay

Ashley Karnay

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Rajan Jain

Rotations:

  • Rajan Jain
  • Andres Blanco
  • Eric Joyce

Kelsey Kaeding

Kelsey Kaeding

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Basis for specificity in heterochromatin establishment by zinc finger transcription factors

Advisor(s):

  • Kenneth Zaret

Rotations:

  • Kenneth Zaret
  • Golnaz Vahedi
  • Christopher Brown

My thesis project is about understanding the role that zinc finger proteins play in regulating cell type specific heterochromatin. This will be studied in the…Read More

My thesis project is about understanding the role that zinc finger proteins play in regulating cell type specific heterochromatin. This will be studied in the context of cellular reprogramming from human fibroblast to hepatic, neuronal, and iPSC lineages. The goal is to understand how perturbing specific zinc finger proteins can enhance reprogramming to different lineages.

Dan Ju

Dan Ju

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating barriers to polygenic risk prediction across diverse populations

Advisor(s):

  • Sarah Tishkoff
  • Iain Mathieson

Rotations:

  • Iain Mathieson
  • Sarah Tishkoff
  • Yana Kamberov

Kelsey Johnson

Kelsey Johnson

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2013

Project Title: Haplotype-based approaches for the study of human evolution

Advisor(s):

  • Benjamin Voight

Rotations:

  • Benjamin Voight
  • Christopher Brown
  • Sarah Tishkoff

Monica Jimenez

Monica Jimenez

Genetics and Epigenetics
Degree: VMD/PhD
Matriculation Year: 2015

Project Title: The gut microbiota regulates the progression of obesity and white adipose tissue inflammation via a highly conserved family of microRNAs

Advisor(s):

  • Jorge Henao-Mejia

Rotations:

  • Montserrat Anguera
  • Michael Silverman
  • Jorge Henao-Mejia

Connie Jiang

Connie Jiang

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2015

Project Title: Revealing the molecular underpinnings of transcriptional heterogeneity

Advisor(s):

  • Arjun Raj

Rotations:

  • Klaus Kaestner
  • Golnaz Vahedi
  • Arjun Raj

Naveen Jain

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Lineage Analysis of Cellular States Predicting Reprogramming into iPSCs

Advisor(s):

  • Arjun Raj

Rotations:

  • Arjun Raj
  • Daniel Rader
  • John Murray

Connor Hill

Connor Hill

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Alessandro Gardini

Rotations:

  • Alessandro Gardini
  • Gerd Blobel
  • Roberto Bonasio

Carolina Gracia Diaz

Carolina Gracia Diaz

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Naiara Aquizu Lopez

Rotations:

  • Jennifer Kalish
  • Naiara Aquizu Lopez
  • Erica Korb

Bridget Gosis

Bridget Gosis

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2015

Project Title:

Advisor(s):

  • Zoltan Arany

Rotations:

  • Zoltan Arany
  • Ben Stanger
  • Jennifer Phillips-Cremins

Katerina Gawronski

Katerina Gawronski

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Evaluating the role of genetic variation in the development of cardiometabolic disease

Advisor(s):

  • Christopher Brown
  • Benjamin Voight

Rotations:

  • Maja Bucan
  • Benjamin Voight
  • Christopher Brown

Yee Hoon Foong

Yee Hoon Foong

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Mitchell Lazar

Rotations:

  • Andy Minn
  • Zhaolan Zhou
  • Eric Joyce

Adam Fenton

Adam Fenton

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating the role of TRAK proteins as motor adaptors for mitochondrial transport in neurons

Advisor(s):

  • Erika Holzbaur
  • Thomas Jongens

Rotations:

  • Roberto Bonasio
  • Erika Holzbaur
  • Thomas Jongens

Niklaus Evitt

Niklaus Evitt

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Multiplexing CRISPR/Cas9-based Continuous Evolution for Improved Epigenome Editing

Advisor(s):

  • Junwei Shi
  • Rahul Kohli

Rotations:

  • Kiran Musunuru
  • Rahul Kohli
  • Junwei Shi

Hoang Bui Nguyen

Hoang Bui Nguyen

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Dichotomous Engagement of HDAC3 Catalytic Activity Governs Inflammatory Responses

Advisor(s):

  • Mitchell Lazar

Rotations:

  • Andy Minn
  • Mitchell Lazar

Desiree Alexander

Desiree Alexander

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Shelley Berger

Rotations:

  • Roberto Bonasio
  • Shelley Berger
  • Marisa Bartolomei

My research revolves around nuclear acetyl-CoA metabolism and its contributions to histone acetylation and gene transcription in neurons. I am particularly interested in how the…Read More

My research revolves around nuclear acetyl-CoA metabolism and its contributions to histone acetylation and gene transcription in neurons. I am particularly interested in how the metabolic enzyme ACSS2 is recruited to the chromatin and how this recruitment impacts learning and memory in mice.

Jennifer Aleman

Jennifer Aleman

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Nuclear pore protein Megator attenuates dosage compensation of the male X chromosome

Advisor(s):

  • Maya Capelson

Rotations:

  • Maya Capelson
  • David Raizen
  • Mia Levine

Krzysztof Wojtak

Krzysztof Wojtak

Gene Therapy and Vaccines
Degree: MD/PhD
Matriculation Year: 2010

Project Title: Novel synthetic DNA technologies targeting cancer and infectious diseases

Advisor(s):

  • David Weiner

Rotations:

  • Drew Weissman
  • James Wilson

Katherine Quiroz-Figueroa

Katherine Quiroz-Figueroa

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2015

Project Title: Characterizing the Physiological and Molecular Mechanism by Which hepatic Trib1 Regulates Plasma Lipids in Mice

Advisor(s):

  • Daniel Rader

Rotations:

  • Jean Bennett
  • Daniel Rader
  • Susan Weiss

Matthew Pine

Matthew Pine

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Drew Weissman

Rotations:

  • John Wherry
  • Drew Weissman
  • Scott Hensley

Joangela Nouel

Joangela Nouel

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Elizabeth White

Rotations:

  • Paul Bates
  • Drew Weissman
  • Elizabeth White

Julia Noll

Julia Noll

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

  • Michael Milone
  • Joseph Fraietta

Richard (Alex) Martino

Richard (Alex) Martino

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Understanding the Mechanisms of PHP.B Transport Across the Murine Blood-Brain Barrier

Advisor(s):

  • James Wilson

Rotations:

  • Kiran Musunuru
  • James Wilson
  • Jeffrey Saven

Colby Maldini

Colby Maldini

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • James Riley

Rotations:

  • Michael Betts
  • James Riley
  • John Wherry

Suying Liu

Suying Liu

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: The role of a gut microbiota-induced lncRNA in regulating intestinal epithelial cells

Advisor(s):

  • Jorge Henao-Mejia

Rotations:

  • Junwei Shi
  • Aimee Payne
  • Jorge Henao-Mejia

Jonathan Lang

Jonathan Lang

Gene Therapy and Vaccines
Degree: MD/PhD
Matriculation Year: 2014

Project Title: Mechanisms of adeno-associated virus (AAV) transduction and AAV-mediated gene editing

Advisor(s):

  • Beverly Davidson

Rotations:

  • Beverly Davidson
  • Amita Sehgal
  • Drew Weissman

Coral Kasden

Coral Kasden

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Hansell Stedman

Rotations:

  • Joshua Dunaief
  • Hansell Stedman
  • Daniel Rader

Inyoung (Ethan) Jung

Inyoung (Ethan) Jung

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Joseph Fraietta

Rotations:

  • Jan Melenhorst
  • Joseph Fraietta
  • Shelley Berger

Jeremy Grevet

Jeremy Grevet

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2011

Project Title: Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.

Advisor(s):

  • Gerd Blobel

Rotations:

  • Gerd Blobel
  • Edward Morrisey
  • Ben Garcia

Kelly Fagan

Kelly Fagan

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title:

Advisor(s):

  • Beverly Davidson

Rotations:

  • John Wolfe
  • Beverly Davidson
  • Stefano Rivella

McKensie Collins

McKensie Collins

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Understanding the Relative Failure of CAR T cell therapy in CLL: An Epigenetic Perspective

Advisor(s):

  • Jan Melenhorst

Rotations:

  • Constantinos Koumenis
  • Jan Melenhorst
  • Junwei Shi

Dongwook (Chris) Choe

Dongwook (Chris) Choe

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: Assaying the potential cardioprotective effect of MTSS1 downregulation against dilated cardiomyopathy

Advisor(s):

  • Kiran Musunuru

Rotations:

  • Frederic Bushman
  • Stefano Rivella
  • Kiran Musunuru

Sangya Agarwal

Sangya Agarwal

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Investigating the role of cell-intrinsic checkpoint regulators PD1 and CTLA4 in Chimeric antigen receptor T cells

Advisor(s):

  • Carl June

Rotations:

  • Carolina Lopez
  • Carl June
  • Janis Burkhardt

Yixin Zang

Yixin Zang

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Crossing the Midline Requires Sequential Proteolysis of the Attractive Frazzled Axon Guidance Receptor

Advisor(s):

  • Greg Bashaw

Rotations:

  • Greg Bashaw
  • Jonathan Raper

Rebecca Windmueller

Rebecca Windmueller

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Advisor(s):

  • Edward Morrisey

Rotations:

  • Edward Morrisey
  • John Wolfe
  • Jason Burdick

Aaron Weiner

Aaron Weiner

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Project Title: The role of ΔNp63 in maladaptive regeneration and repair following severe pulmonary injury

Advisor(s):

  • Andrew Vaughan

Rotations:

  • Rajan Jain
  • Andrew Vaughan
  • Ling Qin

Francesca Tuazon

Francesca Tuazon

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2011

Project Title: Understanding the role of Bmp1a/Tld metalloprotease activity in the spatiotemporal regulation of the BMP morphogen gradient in the developing zebrafish embryo

Advisor(s):

  • Mary Mullins

Rotations:

  • Mary Mullins
  • Nancy Bonini
  • Michael Lampson

Oscar (Will) Towler

Oscar (Will) Towler

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2011

Project Title: Dysregulated BMP signaling through ACVR1 causes impaired joint development and maintenance in fibrodysplasia ossificans progressiva (FOP)

Advisor(s):

  • Eileen Shore

Rotations:

  • Douglas Epstein
  • Eileen Shore
  • Shannon Fisher

Benjamin Tajer

Benjamin Tajer

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2012

Advisor(s):

  • Mary Mullins

Rotations:

  • Mary Mullins
  • Peter Klein
  • Jonathan Raper

Kelly Sullivan

Kelly Sullivan

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

  • Greg Bashaw

Rotations:

  • Wenqin Luo
  • Mary Mullins
  • Greg Bashaw

Kamen Simeonov

Kamen Simeonov

Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2014

Project Title: Single cell CRISPR lineage tracing of cancer metastasis

Advisor(s):

  • Christopher Lengner

Rotations:

  • Joe Baur
  • Gerd Blobel
  • Christopher Lengner
  • John Murray

Isabel Sierra

Isabel Sierra

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Investigating the nuclear organization of the inactive X in female lymphocytes

Advisor(s):

  • Montserrat Anguera

Rotations:

  • Michael Granato
  • Montserrat Anguera
  • Marisa Bartolomei

David Sidibe

David Sidibe

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Sandra Maday

Rotations:

  • Kelvin Luk
  • Isaac Chen
  • Sandra Maday

Samantha Russell

Samantha Russell

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Project Title: The Frazzled receptor is required for oocyte development independently of its ligand Netrin

Advisor(s):

  • Greg Bashaw

Rotations:

  • Greg Bashaw
  • Michael Granato
  • Douglas Epstein

Joel Rurik

Joel Rurik

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Jonathan Epstein

Rotations:

  • Mark Kahn
  • Jonathan Epstein
  • Edward Morrisey

Gabriella Rice

Gabriella Rice

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Panteleimon Rompolas

Rotations:

  • Christopher Lengner
  • Panteleimon Rompolas
  • Diana Stanescu

Ernest Monahan Vargas

Ernest Monahan Vargas

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

  • Yuanquan Song

Rotations:

  • Greg Bashaw
  • Michael Granato
  • Yuanquan Song
  • Judith Grinspan

Lillian Lim

Lillian Lim

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Project Title: Roles of VEGFC and VEGFR3 in lymphangiogenesis and angiogenesis

Advisor(s):

  • Mark Kahn

Rotations:

  • Mark Kahn
  • Jonathan Epstein
  • Richard Assoian

Derek Liberti

Derek Liberti

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Alveolar plasticity drives lung repair and regeneration via Klf5

Advisor(s):

  • Edward Morrisey

Rotations:

  • Paul Gadue
  • Edward Morrisey
  • Panteleimon Rompolas

Hannah Kolev

Hannah Kolev

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Determining the role of UTX and JMJD3, two H3K27me3 demethylases, in the intestinal epithelium during homeostasis and regeneration

Advisor(s):

  • Klaus Kaestner

Rotations:

  • Greg Bashaw
  • Christopher Lengner
  • Klaus Kaestner

Siddharth Kishore

Siddharth Kishore

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: The role of GATA6 in human pancreas development and pancreas agenesis

Advisor(s):

  • Paul Gadue

Rotations:

  • Stewart Anderson
  • Paul Gadue
  • Donguen Huh

William Jones

William Jones

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Mary Mullins

Rotations:

  • Mary Mullins
  • Peter Klein
  • Marisa Bartolomei

Nicholas Holdreith

Nicholas Holdreith

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Inhibition of LNK (SH2B3) enhances function and engraftment of human hematopoietic stem and progenitor cells

Advisor(s):

  • Wei Tong

Rotations:

  • Peter Klein
  • Montserrat Anguera
  • Roberto Bonasio
  • Wei Tong

Maya Hale

Maya Hale

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Greg Bashaw

Rotations:

  • Mary Mullins
  • Zhaolan Zhou
  • Greg Bashaw

Melody Esmaeili Ghahfarokhi

Melody Esmaeili Ghahfarokhi

Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2011

Advisor(s):

  • Peter Klein

Rotations:

  • Mark Kahn
  • Igor Brodsky
  • Mitch Weiss
  • Peter Klein

Zeenat Diwan

Zeenat Diwan

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Project Title: Unravelling the Molecular Mechanisms Regulating Blood Vessel Diameters

Advisor(s):

  • Arndt Siekmann

Alexander Dimitri

Alexander Dimitri

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Joseph Fraietta

Rotations:

  • Paul Gadue
  • Daniel Rader
  • Joseph Fraietta

Ryan Daniels

Ryan Daniels

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

  • Robert Mauck

Rotations:

  • Ling Qin
  • Robert Mauck
  • Jason Burdick

Ryan Cheng

Ryan Cheng

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Advisor(s):

  • Jonathan Raper

Rotations:

  • Jonathan Raper
  • Michael Pack
  • Ben Stanger

My lab uses the developing olfactory system of larval zebrafish as a model to study the formation of neural circuitry. My thesis project is to…Read More

My lab uses the developing olfactory system of larval zebrafish as a model to study the formation of neural circuitry. My thesis project is to investigate the role of a few classical axon guidance factors and their role in the development of olfactory circuitry. Specifically, I am interested in the role that nrp2a, nrp2b, and sema3fa play in the differential axon targeting of OMP and TRPC2 expressing olfactory sensory neurons.

Jessica Brandt

Jessica Brandt

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

  • Jonathan Raper

Rotations:

  • Sandra Maday
  • Arndt Siekmann
  • Michael Granato

Sara Borst

Sara Borst

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Investigating the mechanism of familial thrombocytopenia resulting from mono-allelic mutations in ETV6 or RUNX1 using the human pluripotent stem cell model

Advisor(s):

  • Paul Gadue

Rotations:

  • Christopher Lengner
  • Paul Gadue
  • Anil Rustgi
  • Michael Pack

Robyn Allen

Robyn Allen

Developmental, Stem Cell and Regenerative Biology
Degree: VMD/PhD
Matriculation Year: 2012

Project Title: FOP-ACVR1 Signals by Multiple Modalities in the Developing Zebrafish

Advisor(s):

  • Mary Mullins
  • Eileen Shore