Current Students
Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2020
Advisor(s):
- Emily Partridge
Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2020
Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2020
Microbiology, Virology, and Parasitology
Degree: PhD
Matriculation Year: 2020
Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2020
Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2020
Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2020
Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2019
Rotations:
- Rahul Kohli
Microbiology, Virology, and Parasitology
Degree: VMD/PhD
Matriculation Year: 2008
Advisor(s):
- Alice Chen-Plotkin
Rotations:
- Susan Weiss
- Alice Chen-Plotkin
- David Artis
- Aaron Gitler
In the vast majority of cases of amyotrophic lateral sclerosis and ~50% of the cases of frontotemporal lobar degeneration, pathology is characterized by mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43) in neurons and glia. Research has emphasized TDP-43’s role as an RNA binding protein and despite in vitro characterization of TDP-43’s ability to bind DNA, a genome-wide DNA binding map has yet to be defined. Therefore, I am studying the DNA binding characteristics of TDP-43 in human cells via ChIP-Seq and subsequent biochemical analysis.
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Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Project Title: Genome Wide CRISPR/Cas9 Knockout Screen Identifies Host Genes Important for Cryptosporidium parvum Infection
Advisor(s):
- Boris Striepen
Cancer Biology
Degree: PhD
Matriculation Year: 2015
Project Title: Determining the coordinated inhibitory molecule expression profile of tumor-reactive TIL and their relationship to CD137+ TIL relative dysfunction and anti-tumor potency
Advisor(s):
- Daniel Powell
Rotations:
- Margaret Chou
- Daniel Powell
- Celeste Simon
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Project Title: Innate immunity in primary neurons: specialized responses to viral infection
Advisor(s):
- Sara Cherry
Rotations:
- Scott Hensley
- Paul Bates
- Sara Cherry
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Bradley Johnson
Rotations:
- Craig Bassing
- Roger Greenberg
- Bradley Johnson
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Frederic Bushman
Rotations:
- Frederic Bushman
- Elizabeth Grice
- Scott Hensley
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Project Title: The role of PTPN14 inactivation by HPV E7 in the differentiation-dependent HPV life cycle
Advisor(s):
- Elizabeth White
Rotations:
- Carolina Lopez
- Elizabeth White
- Susan Weiss
Cancer Biology
Degree: PhD
Matriculation Year: 2016
Project Title: The Role of the Endothelin B Receptor in Macrophage Function
Advisor(s):
- Malay Haldar
Rotations:
- Ben Stanger
- Anil Rustgi
- Malay Haldar
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Igor Brodsky
Rotations:
- Joseph St Geme
- Igor Brodsky
- Christoph Thaiss
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- David Feldser
Rotations:
- Donita Brady
- David Feldser
- Luca Busino
Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2016
Project Title: The role of retrograde trafficking during cellular entry by severe fever with thrombocytopenia syndrome virus
Advisor(s):
- Paul Bates
Rotations:
- Ronald Harty
- Paul Bates
- Elizabeth White
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Project Title: Defining the Mechanism and Function of DNA Double Strand Break Induced Inhibition of V(D)J Recombination
Advisor(s):
- Craig Bassing
Rotations:
- John Maris
- Ronny Drapkin
- Craig Bassing
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015
Advisor(s):
- Joseph St Geme
Rotations:
- Joseph St Geme
- Frederic Bushman
- Ronald Collman
Cancer Biology
Degree: PhD
Matriculation Year: 2016
Project Title: Glucagon signaling in liver cancer
Advisor(s):
- Celeste Simon
Rotations:
- Tzipora Sarah Karin Eisinger
- Nicola Mason
- Celeste Simon
Hepatocellular carcinoma (HCC) is the second most lethal type of cancer in the world and lacks effective targeted therapies, in part, due to its genetic heterogeneity. Altered cellular metabolism that promotes tumor growth represents a common feature in HCC. I will explore epigenetic mechanisms by which these metabolic phenotypes exist to discover new therapeutic strategies for a wider patient population.
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Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016
Project Title: Dissecting the Immune Response to Merkel Cell Polyomavirus Infection
Advisor(s):
- Jianxin You
Rotations:
- Matthew Weitzman
- Jianxin You
- Igor Brodsky
Cancer Biology
Degree: PhD
Matriculation Year: 2016
Project Title: Developing a genetic platform to identify cullin-RING ubiquitin ligase roles in cancer
Advisor(s):
- Luca Busino
Rotations:
- Luca Busino
- Bradley Johnson
- Zoltan Arany
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Celeste Simon
Rotations:
- Mark Kahn
- Yi Fan
- Celeste Simon
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016
Project Title: Evasion of Human Innate Immunity by Coxiella burnetii
Advisor(s):
- Sunny Shin
Rotations:
- Michael Betts
- Sunny Shin
- Paul Planet
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Elizabeth Grice
Rotations:
- Elizabeth Grice
- David Weiner
- Carolina Lopez
Cancer Biology
Degree: VMD/PhD
Matriculation Year: 2019
Rotations:
- Zachary Schug
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016
Project Title: Developing improved vaccine platforms against severe fever with thrombocytopenia syndrome virus
Advisor(s):
- Paul Bates
Rotations:
- Carolina Lopez
- Laurence Eisenlohr
- Paul Bates
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Sandra Ryeom
Rotations:
- Xiaolu Yang
- Dmitry Gabrilovich
- Sandra Ryeom
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Frederic Bushman
Rotations:
- Susan Weiss
- Sara Cherry
- Frederic Bushman
Cancer Biology
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Ben Stanger
Rotations:
- Daniel Powell
- Margaret Chou
- Ben Stanger
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Project Title: Role of Yersinia pseudotuberculosis virulence in granuloma formation during intestinal infection
Advisor(s):
- Igor Brodsky
Rotations:
- Igor Brodsky
- Boris Striepen
- Michael Abt
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Project Title: Defining capsule and exopolysaccharide-independent complement resistance factors in Kingella kingae
Advisor(s):
- Joseph St Geme
Rotations:
- Elizabeth White
- Laurence Eisenlohr
- Joseph St Geme
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Project Title: Role of HMG-box transcription factor TOX in maintaining CD8 T cell exhaustion
Advisor(s):
- John Wherry
Rotations:
- Dmitry Gabrilovich
- Jorge Henao-Mejia
- John Wherry
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- George Shaw
Rotations:
- George Shaw
- Katharine Bar
- Michael Betts
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Project Title: Investigating the role of ACLY and acetyl-CoA metabolism in hepatocellular carcinoma
Advisor(s):
- Kathryn Wellen
Rotations:
- Kathryn Wellen
- Wei Tong
- Martin Carroll
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Margaret Chou
Rotations:
- Andy Minn
- Saar Gill
- Dmitry Gabrilovich
- Gregory Beatty
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016
Advisor(s):
- Sunny Shin
Rotations:
- Scott Hensley
- Sunny Shin
- Paul Planet
I am studying how the human immune system recognizes Salmonella, which causes diarrheal disease. Salmonella initially invades and replicates within intestinal epithelial cells by using type III secretion systems (T3SSs) to inject proteins into host cells. I am studying the role of a cytosolic sensor called human NAIP (hNAIP) during Salmonella infection. I will determine which T3SS components are sensed by hNAIP, what response hNAIP mounts, and whether these responses control bacterial infection.
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Cancer Biology
Degree: PhD
Matriculation Year: 2015
Project Title: Investigating the immunometabolism and anti-tumor properties of invariant natural killer T (iNKT) cells in neuroblastoma
Advisor(s):
- Hamid Bassiri
Rotations:
- Roger Greenberg
- Maureen Murphy
- Hamid Bassiri
Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2015
Project Title: Investigating the innate immune antagonistic effects of the multifunctional C15 protein of Ectromelia virus
Advisor(s):
- Laurence Eisenlohr
Rotations:
- Matthew Weitzman
- Scott Hensley
- Laurence Eisenlohr
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015
Advisor(s):
- Joseph St Geme
Rotations:
- Joseph St Geme
- Kimberly Gallagher
- Mechthild Pohlschroder
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015
Project Title: Determining the Mechanism of TNF-Mediated Defense Against Intracellular Legionella pneumophila Infection
Advisor(s):
- Sunny Shin
Rotations:
- Phillip Scott
- Michael Povelones
- Sunny Shin
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Susan Weiss
Rotations:
- Matthew Weitzman
- Susan Weiss
- Kristen Lynch
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Project Title: Investigating the Roles of Activation-Induced Cytidine Deaminase in theMalignant Progression of Chronic Lymphocytic Leukemia
Advisor(s):
- Andrew Hu
Rotations:
- Tzipora Sarah Karin Eisinger
- Andrew Hu
- Oliver Garden
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Project Title: Understanding and Overcoming Melanoma Resistance to GPCR-based Therapy
Advisor(s):
- Todd Ridky
Rotations:
- David Feldser
- Todd Ridky
- Gerald Linette
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016
Advisor(s):
- Paul Planet
Rotations:
- Paul Planet
- Dustin Brisson
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Gregory Beatty
Rotations:
- John Maris
- Saar Gill
- Gregory Beatty
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016
Project Title: Investigating the Role of STING during enteric RNA virus infection in Drosophila
Advisor(s):
- Sara Cherry
Rotations:
- Sara Cherry
- Harvey Friedman
- Laurence Eisenlohr
Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2018
Project Title: The Ups and Downs of Host Regulation of Ebola Hemorrhagic Fever Virus Egress
Advisor(s):
- Ronald Harty
Rotations:
- Beatrice Hahn
- Matthew Weitzman
- Ronald Harty
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Joseph Zackular
Rotations:
- James Riley
- Joseph Zackular
- Michael Silverman
Cancer Biology
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Malay Haldar
- Celeste Simon
Rotations:
- Anil Rustgi
- Malay Haldar
- Celeste Simon
Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2014
Advisor(s):
- Michael Povelones
Rotations:
- Matthew Hayes
- Michael Povelones
- De'Broski Herbert
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Project Title: Defining the proteins responsible for establishing C. parvum infection
Advisor(s):
- Boris Striepen
Rotations:
- Carolina Lopez
- Boris Striepen
- David Weiner
Cancer Biology
Degree: PhD
Matriculation Year: 2016
Project Title: TOX2 as a novel regulator of central memory phenotype in CAR T cells
Advisor(s):
- Shelley Berger
Rotations:
- Paul Lieberman
- Shelley Berger
- Gerd Blobel
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Will Bailis
Rotations:
- Christopher Hunter
- Warren Pear
- Will Bailis
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Celeste Simon
Rotations:
- Celeste Simon
- Terrance Gade
- Liming Pei
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Kathryn Wellen
- Zoltan Arany
Rotations:
- Zachary Schug
- Kathryn Wellen
- Zoltan Arany
Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Elizabeth Grice
Rotations:
- Matthew Weitzman
- Kai Tan
- Elizabeth Grice
Cancer Biology
Degree: PhD
Matriculation Year: 2014
Project Title: Calcium signaling induces a partial EMT in carcinoma cells
Advisor(s):
- Ben Stanger
Rotations:
- Ben Stanger
- Kathryn Wellen
- Ian Blair
Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Elizabeth Grice
Rotations:
- Elizabeth Grice
- Michael Silverman
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Kathryn Hamilton
Rotations:
- Andrew Hu
- Lewis Chodosh
- Kathryn Hamilton
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017
Project Title: Role of KLRG1 signaling on CD8+ T-cells during chronic HIV infection
Advisor(s):
- Michael Betts
Rotations:
- Frederic Bushman
- Michael Betts
- Elizabeth Grice
Cancer Biology
Degree: PhD
Matriculation Year: 2016
Project Title: The Impact of Astrocytes on the Response of Melanoma Brain Metastases to Targeted Therapy
Advisor(s):
- Maureen Murphy
Rotations:
- Anil Rustgi
- John Maris
- Maureen Murphy
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Jianxin You
Rotations:
- Jianxin You
- Ronald Collman
- Dennis Kolson
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Vikram Paralkar
Rotations:
- Margaret Chou
- Vikram Paralkar
- Paul Lieberman
Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Sunny Shin
- Igor Brodsky
Rotations:
- Sunny Shin
- Joseph Zackular
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Joe Baur
Rotations:
- Joe Baur
- Douglas Wallace
- Zachary Schug
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Gerd Blobel
Rotations:
- Junwei Shi
- Gerd Blobel
- Alessandro Gardini
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Ronny Drapkin
Rotations:
- Roger Greenberg
- Rugang Zhang
- Ronny Drapkin
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018
Rotations:
- Ivan Maillard
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Arjun Raj
Rotations:
- Jennifer Phillips-Cremins
- Arjun Raj
Cancer Biology
Degree: PhD
Matriculation Year: 2016
Project Title: Splicing Variation Contributes to Functional Dysregulation of AML-associated Genes
Advisor(s):
- Yoseph Barash
- Kristen Lynch
Rotations:
- Andrei Thomas-Tikhonenko
- Irfan Asangani
- Yoseph Barash
- John Lynch
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Paul Planet
Rotations:
- Paula Oliver
- Mark Goulian
- Paul Planet
Cancer Biology
Degree: PhD
Matriculation Year: 2014
Project Title: Response to Stress by the Tumor Microenvironment
Advisor(s):
- Sandra Ryeom
Rotations:
- Sandra Ryeom
- John Lynch
- Constantinos Koumenis
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Melike Lakadamyali
Rotations:
- Melike Lakadamyali
- Erika Holzbaur
- Paul Janmey
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Lewis Chodosh
- Todd Ridky
- George Burslem
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Patrick Grohar
Rotations:
- Bradley Johnson
- Paul Lieberman
- Patrick Grohar
Cancer Biology
Degree: PhD
Matriculation Year: 2015
Project Title: Genetic Determinants of Recurrence in BRCA1/2 Breast and Ovarian Cancers
Advisor(s):
- Katherine Nathanson
Rotations:
- John Lynch
- John Maris
- Tzipora Sarah Karin Eisinger
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Rotations:
- Naiara Aquizu Lopez
- Greg Bashaw
- Thomas Jongens
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Paul Titchenell
Rotations:
- Tzipora Sarah Karin Eisinger
- Paul Titchenell
- Patrick Seale
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Andres Blanco
Rotations:
- Montserrat Anguera
- Andres Blanco
- Brian Capell
Microbiology, Virology, and Parasitology
Degree: PhD
Matriculation Year: 2018
Project Title: Defining the protective role of prostaglandins during Clostridioides difficile infection
Advisor(s):
- Joseph Zackular
Rotations:
- Kathryn Hamilton
- Joseph Zackular
- Thomas DeRaedt
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Laurence Eisenlohr
Rotations:
- Laurence Eisenlohr
- Sara Cherry
- Boris Striepen
Cancer Biology
Degree: PhD
Matriculation Year: 2015
Project Title: Investigating the role of mutant p53 in lung metastasis in esophageal squamous cell carcinoma
Advisor(s):
- Anil Rustgi
Rotations:
- Celeste Simon
- Anil Rustgi
- Roger Greenberg
Cancer Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Michael Betts
- John Maris
Rotations:
- John Maris
- Michael Betts
- Joseph Fraietta
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018
Rotations:
- Katalin Susztak
Cancer Biology
Degree: PhD
Matriculation Year: 2016
Project Title: Paradoxical YAP activation as an emergent limitation to Cu chelation therapy in BRAFV600E-driven melanoma
Advisor(s):
- Donita Brady
Rotations:
- Donita Brady
- Kathryn Wellen
- Constantinos Koumenis
Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2018
Rotations:
- Scott Hensley
Cell Biology, Physiology, and Metabolism
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Melike Lakadamyali
Rotations:
- Meera Sundaram
- Melike Lakadamyali
- Tatyana Svitkina
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Stefano Rivella
- Saar Gill
Rotations:
- Michael Milone
- Saar Gill
- Stefano Rivella
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Project Title: The role of Epigenetic Regulators in Restricting LSD1i-Mediated Differentiation in Acute Myeloid Leukemia
Advisor(s):
- Andres Blanco
Rotations:
- Ben Stanger
- David Feldser
- Andres Blanco
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- David Feldser
- Maureen Murphy
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Project Title: Pattern recognition receptor signaling in immune checkpoint blockade resistance
Advisor(s):
- Andy Minn
Rotations:
- Andy Minn
- Junwei Shi
- Shelley Berger
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Susan Weiss
Rotations:
- Kellie Jurado
- Paul Bates
- Susan Weiss
Cancer Biology
Degree: PhD
Matriculation Year: 2014
Advisor(s):
- Xiaolu Yang
Rotations:
- Shelley Berger
- Xiaolu Yang
- Gerd Blobel
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- De'Broski Herbert
Rotations:
- Sara Cherry
- Michaela Locci
- Frederic Bushman
Cancer Biology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Yi Fan
Rotations:
- Youhai Chen
- Celeste Simon
- Kathryn Wellen
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Constantinos Koumenis
- Patrick Grohar
- Lewis Chodosh
- Ronny Drapkin
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Zoltan Arany
Rotations:
- Zoltan Arany
- Doris Stoffers
- Joe Baur
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2019
Rotations:
- Bradley Johnson
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015
Project Title: The Roundabout receptor recruits the Scar/Wave Complex to control axon guidance at the midline
Advisor(s):
- Greg Bashaw
Rotations:
- Michael Marks
- Janis Burkhardt
- Greg Bashaw
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Rotations:
- Brian Capell
- Nancy Bonini
- David Feldser
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017
Project Title: Cyclin B3 is an essential factor in female fertility and embryonic development
Advisor(s):
- Jeremy Wang
Rotations:
- Jeremy Wang
- Yana Kamberov
- Marisa Bartolomei
Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2018
Rotations:
- Carolina Lopez
- Will Bailis
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017
Project Title: A mechanistic investigation into F-actin assembly on mitochondria as a wave
Advisor(s):
- Erika Holzbaur
Rotations:
- Erika Holzbaur
- Michael Ostap
- James Shorter
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Matthew Weitzman
Rotations:
- Dieter Schifferli
- Matthew Weitzman
- Paul Lieberman
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Daniel Kulp
- George Shaw
Rotations:
- Daniel Kulp
- George Shaw
- Scott Hensley
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2013
Project Title: Tumor RIPK1 Signaling Mediates Intrinsic and Extrinsic Mechanisms of Resistance to Immune Checkpoint Blockade Therapy
Advisor(s):
- Andy Minn
Rotations:
- Kathryn Wellen
- Mitchell Lazar
- Andy Minn
- Dwight Gilliland
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Daniel Kulp
Rotations:
- Daniel Powell
- Michael Mitchell
- Daniel Kulp
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Elizabeth Bhoj
Rotations:
- Melike Lakadamyali
- Vera Krymskaya
- Liming Pei
- Elizabeth Bhoj
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Joseph St Geme
Rotations:
- Scott Hensley
- Joseph Zackular
- Joseph St Geme
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016
Project Title: Corneal nerves constitute a functional stem cell niche for epithelial homeostasis and regeneration
Advisor(s):
- Panteleimon Rompolas
Rotations:
- Mark Kahn
- Panteleimon Rompolas
- Sandra Ryeom
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Joseph Fraietta
Rotations:
- Hamid Bassiri
- Hansell Stedman
- Joseph Fraietta
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014
Project Title: Targeting MCU-mediated Calcium Uptake by Mitochondria for the Development of New Chemotherapies
Advisor(s):
- Kevin Foskett
Rotations:
- Kevin Foskett
- Erika Holzbaur
- Robert Kalb
As a dissertation student my thesis project aims to understand how genetic and pharmacological inhibition of calcium influx into mitochondria, as well as inhibition of calcium transfer from the endoplasmic reticulum (ER) to mitochondria affects the survival of cancer cells in vitro and in vivo. Cancer is characterized by accelerated growth and division of unhealthy cells. While mitochondria are the main organelles that supply the energetic needs of cells through oxidative phosphorylation, the most prominent feature of cancer cells is a remodeled cell metabolism based on constitutive aerobic glycolysis. It is then reasonably assumed that the biological function of mitochondria as the “powerhouse of the cell” is diminished in cancer cells.
On the other hand, the unexpected finding from our lab published by Cardenas et al., (2016), revealed that constitutive influx of calcium into mitochondria is indispensable for survival of cancer cells. Therefore, I propose that calcium signaling from the ER to mitochondria, as well as calcium influx to mitochondria can be independently targeted for the development of novel chemotherapeutics to selectively damage and kill cancer cells. While the Foskett lab is recognized by the international scientific community as a significant contributor in many research areas, such as calcium signaling, the development of my project in cancer biology will enrich the expertise of the lab. Furthermore, I expect that the knowledge gained from my research will be employed to optimize and increase current chemotherapies.
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Cancer Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Dmitry Gabrilovich
- Ben Stanger
- Chengcheng Jin
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Zoltan Arany
Rotations:
- Zoltan Arany
- Benjamin Prosser
- Kenneth Margulies
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Celeste Simon
Rotations:
- Celeste Simon
- Ben Stanger
- Liling Wan
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015
Advisor(s):
- Yale Goldman
Rotations:
- Marc Vermulst
- Rugang Zhang
- Edward Lee
- Ronen Marmorstein
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017
Project Title: Enhancing antitumor cytotoxicity of natural killer cells by increasing their intracellular pH
Advisor(s):
- Chi Dang
Rotations:
- Chi Dang
- Mitchell Lazar
- Celeste Simon
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016
Project Title: How do the molecular pathways of mitophagy intersect with those of inflammation in neurons; and are these pathways, and their disruption, implicated in the etiology of ALS and other neurodegenerative diseases?
Advisor(s):
- Erika Holzbaur
Rotations:
- Chi Dang
- Erika Holzbaur
- Marc Vermulst
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Kenneth Zaret
Rotations:
- Gerd Blobel
- Kenneth Zaret
- Melike Lakadamyali
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015
Advisor(s):
- Benjamin Prosser
Rotations:
- Michael Granato
- Greg Bashaw
- Benjamin Prosser
Cardiac myocytes are unique in their constant and cyclic exposure to mechanical forces as the heart beats. It has been well-known for decades that changes in these mechanical forces can contribute to heart disease, but the mechanism by which changes to stress and strain cause pathology remains unclear. My project focuses on the role of the cytoskeleton in sensing and responding to changes in mechanical stress and strain in cardiomyocytes and how those changes contribute to disease.
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Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Christopher Lengner
Rotations:
- Panteleimon Rompolas
- Andrew Vaughan
- Christopher Lengner
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Patrick Seale
Rotations:
- Zoltan Arany
- Mitchell Lazar
- Patrick Seale
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Andy Minn
- Maayan Levy
- John Wherry
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Daniel Kulp
Rotations:
- Daniel Kulp
- Norbert Pardi
- Mike Farwell
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014
Advisor(s):
- Sandra Maday
Rotations:
- Mitchell Lazar
- Claudio Giraudo
- Wei Guo
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2018
Project Title: Investigating the role of the histone variant H2BE in glial cell senescence in the brain
Advisor(s):
- Erica Korb
Rotations:
- Jennifer Phillips-Cremins
- James Shorter
- Erica Korb
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Thomas DeRaedt
- Yael Mosse
- Celeste Simon
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Anna Kashina
Rotations:
- Anna Kashina
- Erika Holzbaur
- Erfei Bi
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Peter Choi
Rotations:
- Andy Minn
- Marco Ruella
- Peter Choi
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015
Advisor(s):
- Zoltan Arany
Rotations:
- Michael Marks
- Benjamin Prosser
- Zoltan Arany
Developmental, Stem Cell, and Regenerative Biology
Degree: VMD/PhD
Matriculation Year: 2018
Rotations:
- Robert Mauck
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016
Project Title: The effects of hyper MAPK/ERK signaling on dendritic cell immune functions
Advisor(s):
- Edward Behrens
Rotations:
- Joshua Dunaief
- Mitchell Lazar
- Edward Behrens
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018
Advisor(s):
- Arjun Raj
Rotations:
- Mitchell Lazar
- Arjun Raj
Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2014
Advisor(s):
- Zoltan Arany
Rotations:
- Zoltan Arany
- Hao Wu
- Adam Resnick
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018
Rotations:
- Kathryn Wellen
Gene Therapy and Vaccines
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- James Wilson
Rotations:
- Kiran Musunuru
- James Wilson
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016
Advisor(s):
- Edward Lee
Rotations:
- Kelly Jordan-Sciutto
- Edward Lee
- Robert Kalb
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Rotations:
- Mia Levine
- Alessandro Gardini
- Junwei Shi
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Matthew Weitzman
Rotations:
- Scott Hensley
- Matthew Weitzman
- Daniel Beiting
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017
Project Title: Explore the mechanisms underlying irradiation-induced immunomodulation in cancer therapy
Advisor(s):
- Andy Minn
Rotations:
- Foteini Mourkioti
- Andy Minn
- Eric Witze
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Maureen Murphy
- Malay Haldar
- Peter Choi
- Irfan Asangani
Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2015
Advisor(s):
- Mark Kahn
Rotations:
- Mark Kahn
- Robert Heuckeroth
- Jorge Henao-Mejia
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Joseph St Geme
- Paul Planet
Rotations:
- Joseph St Geme
- Paul Planet
- Audrey John
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016
Advisor(s):
- Benjamin Prosser
Rotations:
- Robert Heuckeroth
- Benjamin Prosser
- Christopher Brown
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Paul Gadue
Rotations:
- Paul Gadue
- Stewart Anderson
- Stella Chou
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Zoltan Arany
Rotations:
- Elizabeth Grice
- Zoltan Arany
- Raymond Soccio
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Stephen Dinardo
Rotations:
- Jeremy Wang
- Marisa Bartolomei
- Paul Gadue
Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2016
Project Title: The Role of Metabolism in NF1
Advisor(s):
- Amita Sehgal
Rotations:
- Thomas Jongens
- Amita Sehgal
- Douglas Wallace
Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Mark Kahn
Rotations:
- Mark Kahn
- Edward Morrisey
Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Montserrat Anguera
Rotations:
- Zhaolan Zhou
- Lewis Chodosh
- Montserrat Anguera
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016
Project Title: Mechanistic dissection of novel regulators of TDP-43 aggregation identified in a genome-wide CRISPR-Cas9 knockout screen
Advisor(s):
- Ophir Shalem
Rotations:
- Michael Marks
- Ophir Shalem
- Naiara Aquizu Lopez
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Christopher Hunter
Rotations:
- Sunny Shin
- Christopher Hunter
- Joseph Zackular
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2018
Project Title: Mechanisms driving stress-induced hyperglycemia following trauma
Advisor(s):
- Paul Titchenell
Rotations:
- Paul Titchenell
- Mitchell Lazar
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Elizabeth Bhoj
- Paula Oliver
- Kelly Jordan-Sciutto
Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2016
Project Title: The Impact of Iron on Endolysosomal Function in the Retinal Pigment Epithelium
Advisor(s):
- Joshua Dunaief
Rotations:
- Lewis Chodosh
- Joshua Dunaief
- Vera Krymskaya
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Marco Ruella
Rotations:
- Andrei Thomas-Tikhonenko
- Marco Ruella
- Patrick Grohar
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Igor Brodsky
Rotations:
- Maayan Levy
- Igor Brodsky
- Sara Cherry
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014
Project Title: Investigating the mechanism of familial thrombocytopenia resulting from mono-allelic mutations in ETV6 or RUNX1 using the human pluripotent stem cell model
Advisor(s):
- Paul Gadue
Rotations:
- Christopher Lengner
- Paul Gadue
- Anil Rustgi
- Michael Pack
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Daniel Beiting
Rotations:
- Michael Silverman
- Daniel Beiting
- Kyle Bittinger
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Jonathan Raper
Rotations:
- Sandra Maday
- Arndt Siekmann
- Michael Granato
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Gregory Beatty
Rotations:
- Ben Stanger
- Celeste Simon
- Gregory Beatty
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013
Advisor(s):
- Jonathan Raper
Rotations:
- Jonathan Raper
- Michael Pack
- Ben Stanger
My lab uses the developing olfactory system of larval zebrafish as a model to study the formation of neural circuitry. My thesis project is to investigate the role of a few classical axon guidance factors and their role in the development of olfactory circuitry. Specifically, I am interested in the role that nrp2a, nrp2b, and sema3fa play in the differential axon targeting of OMP and TRPC2 expressing olfactory sensory neurons.
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Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Rotations:
- Marisa Bartolomei
- Greg Bashaw
- Amita Sehgal
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Robert Mauck
Rotations:
- Ling Qin
- Robert Mauck
- Jason Burdick
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Audrey John
Rotations:
- Harvey Friedman
- Audrey John
- Paul Bates
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Joseph Fraietta
Rotations:
- Paul Gadue
- Daniel Rader
- Joseph Fraietta
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Edward Morrisey
- Alex Hughes
- Paula Oliver
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Project Title: Unravelling the Molecular Mechanisms Regulating Blood Vessel Diameters
Advisor(s):
- Arndt Siekmann
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Igor Brodsky
Rotations:
- Igor Brodsky
- Elizabeth White
- Sunny Shin
Cancer Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Zachary Schug
Rotations:
- Kathryn Wellen
- Peter Choi
- Zachary Schug
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Erika Holzbaur
Rotations:
- Erika Holzbaur
- Greg Bashaw
- Matthew Good
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Andy Minn
Rotations:
- Joshua Dunaief
- Andy Minn
- Roger Greenberg
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014
Project Title: Comparative phylogenetics of the dystrophin associated protein complex protein families and implications for Adeno-associated virus (AAV)-mediated gene therapy in Duchenne muscular dystrophy.
Advisor(s):
- Hansell Stedman
Rotations:
- Jonathan Epstein
- Foteini Mourkioti
- Jason Burdick
- Hansell Stedman
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Greg Bashaw
Rotations:
- Mary Mullins
- Zhaolan Zhou
- Greg Bashaw
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2019
Rotations:
- Elizabeth Bhoj
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014
Project Title: Inhibition of LNK (SH2B3) enhances function and engraftment of human hematopoietic stem and progenitor cells
Advisor(s):
- Wei Tong
Rotations:
- Peter Klein
- Montserrat Anguera
- Roberto Bonasio
- Wei Tong
Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2018
Rotations:
- Edward Behrens
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016
Project Title: Identifying necessary chromatin states and targets for hemogenic specification and reprogramming by the transcription factor Runx1
Advisor(s):
- Nancy Speck
Rotations:
- Peter Klein
- Nancy Speck
- Klaus Kaestner
Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Matthew Weitzman
Rotations:
- Scott Hensley
- Paul Bates
- Matthew Weitzman
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2012
Advisor(s):
- Mary Mullins
Rotations:
- Erfei Bi
- Mary Mullins
- Edward Morrisey
The Balbiani body (Bb) is a transient aggregate found within the oocytes of many species, conserved form insects to humans. It shares structural similarities with amyloid plaques that cause degenerative disease. Understanding the Bb will provide insight how amyloid networks form and disassemble in a non-disease context, but few components of the Bb have been characterized. I am using proteomics, live imaging and gene editing to identify novel components of the Bb and discover their function.
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Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2015
Advisor(s):
- Christopher Lengner
Rotations:
- Thomas Leung
- Katalin Susztak
- Rebecca Wells
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Zoltan Arany
Rotations:
- Zoltan Arany
- Vikram Paralkar
- Paul Titchenell
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Mary Mullins
Rotations:
- Mary Mullins
- Peter Klein
- Marisa Bartolomei
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019
Rotations:
- Wei Tong
- Peter Klein
- Rugang Zhang
Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Sandra Maday
Rotations:
- Benjamin Prosser
- Sandra Maday
- Rebecca Ahrens-Nicklas
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017
Project Title: Determining the role of UTX and JMJD3, two H3K27me3 demethylases, in the intestinal epithelium during homeostasis and regeneration
Advisor(s):
- Klaus Kaestner
Rotations:
- Greg Bashaw
- Christopher Lengner
- Klaus Kaestner
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Eric Joyce
Rotations:
- Eric Joyce
- Golnaz Vahedi
- Ophir Shalem
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016
Project Title: Alveolar plasticity drives lung repair and regeneration via Klf5
Advisor(s):
- Edward Morrisey
Rotations:
- Paul Gadue
- Edward Morrisey
- Panteleimon Rompolas
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Beverly Davidson
Rotations:
- George Shaw
- Valder Arruda
- Beverly Davidson
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Jeremy Wilusz
Rotations:
- Kavitha Sarma
- Naiara Aquizu Lopez
- Jeremy Wilusz
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Christopher Brown
- Katherine Nathanson
Rotations:
- Pablo Cámara
- Christopher Brown
- Katherine Nathanson
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013
Project Title: Investigating the Role of TBX3 in Human Endoderm Development
Advisor(s):
- Paul Gadue
Rotations:
- Paul Gadue
- John Murray
- Warren Pear
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Andrew Vaughan
Rotations:
- Andrew Vaughan
- Patrick Seale
- David Frank
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016
Advisor(s):
- Robert Heuckeroth
Rotations:
- Montserrat Anguera
- Robert Heuckeroth
- Mia Levine
I'm studying the role of microRNAs in the development of the enteric nervous system.
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Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2016
Advisor(s):
- Hongjun Song
Rotations:
- Rajan Jain
- Hongjun Song
- Guo-Li Ming
- D. Kacy Cullen
- Jonathan Epstein
Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Hao Shen
Rotations:
- Joseph Zackular
- Hao Shen
- Sunny Shin
Developmental, Stem Cell and Regenerative Biology
Degree: VMD/PhD
Matriculation Year: 2014
Advisor(s):
- Edward Morrisey
Rotations:
- Ben Stanger
- Edward Morrisey
- Christopher Lengner
My thesis is focused on studying the developmental ontogeny and maturation process of alveolar type one cells in the lung.
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Gene Therapy and Vaccines
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Nancy Speck
Rotations:
- Stefano Rivella
- Nancy Speck
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Panteleimon Rompolas
Rotations:
- Christopher Lengner
- Panteleimon Rompolas
- Diana Stanescu
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019
Rotations:
- Katharine Bar
- Maayan Levy
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Jonathan Epstein
Rotations:
- Mark Kahn
- Jonathan Epstein
- Edward Morrisey
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013
Project Title: The Frazzled receptor is required for oocyte development independently of its ligand Netrin
Advisor(s):
- Greg Bashaw
Rotations:
- Greg Bashaw
- Michael Granato
- Douglas Epstein
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Sandra Maday
Rotations:
- Kelvin Luk
- Isaac Chen
- Sandra Maday
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016
Project Title: Investigating the nuclear organization of the inactive X in female lymphocytes
Advisor(s):
- Montserrat Anguera
Rotations:
- Michael Granato
- Montserrat Anguera
- Marisa Bartolomei
Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2014
Project Title: Single cell CRISPR lineage tracing of cancer metastasis
Advisor(s):
- Christopher Lengner
Rotations:
- Joe Baur
- Gerd Blobel
- Christopher Lengner
- John Murray
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016
Advisor(s):
- Greg Bashaw
Rotations:
- Wenqin Luo
- Mary Mullins
- Greg Bashaw
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017
Project Title: The role of ΔNp63 in maladaptive regeneration and repair following severe pulmonary injury
Advisor(s):
- Andrew Vaughan
Rotations:
- Rajan Jain
- Andrew Vaughan
- Ling Qin
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017
Project Title: Determining the role of H3K9me2S10 phosphorylation in peripheral heterochromatin localization
Advisor(s):
- Jonathan Epstein
Rotations:
- Jonathan Epstein
- Mark Kahn
- Melike Lakadamyali
Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016
Project Title: Crossing the Midline Requires Sequential Proteolysis of the Attractive Frazzled Axon Guidance Receptor
Advisor(s):
- Greg Bashaw
Rotations:
- Greg Bashaw
- Jonathan Raper
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016
Project Title: Investigating the role of cell-intrinsic checkpoint regulators PD1 and CTLA4 in Chimeric antigen receptor T cells
Advisor(s):
- Carl June
Rotations:
- Carolina Lopez
- Carl June
- Janis Burkhardt
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Beatriz Carreno
- Gerald Linette
Rotations:
- Katharine Bar
- Jan Melenhorst
- Gerald Linette
- Beatriz Carreno
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016
Project Title: Lentiviral Vectors as Therapeutic Options for the Treatment of Alpha-Thalassemia
Advisor(s):
- Stefano Rivella
Rotations:
- Valder Arruda
- Stefano Rivella
- John Wolfe
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017
Project Title: Assaying the potential cardioprotective effect of MTSS1 downregulation against dilated cardiomyopathy
Advisor(s):
- Kiran Musunuru
Rotations:
- Frederic Bushman
- Stefano Rivella
- Kiran Musunuru
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016
Project Title: Understanding CAR T cell Dysfunction in Chronic Lymphocytic Leukemia
Advisor(s):
- Jan Melenhorst
Rotations:
- Constantinos Koumenis
- Jan Melenhorst
- Junwei Shi
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Beverly Davidson
Rotations:
- John Wolfe
- Beverly Davidson
- Stefano Rivella
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- James Wilson
Rotations:
- Kiran Musunuru
- Stefano Rivella
- James Wilson
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Joseph Fraietta
Rotations:
- Jan Melenhorst
- Joseph Fraietta
- Shelley Berger
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018
Project Title: Developing a safe utrophin-based gene therapy platform through design of novel synthetic muscle-specific promoters and a liver-detargeted Adeno-associated virus 9
Advisor(s):
- Hansell Stedman
Rotations:
- Joshua Dunaief
- Hansell Stedman
- Daniel Rader
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017
Project Title: The role of a gut microbiota-induced lncRNA in regulating intestinal epithelial cells
Advisor(s):
- Jorge Henao-Mejia
Rotations:
- Junwei Shi
- Aimee Payne
- Jorge Henao-Mejia
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016
Project Title: Understanding the Mechanisms of PHP.B Transport Across the Murine Blood-Brain Barrier
Advisor(s):
- James Wilson
Rotations:
- Kiran Musunuru
- James Wilson
- Jeffrey Saven
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Joseph Fraietta
Rotations:
- Michael Milone
- Joseph Fraietta
- James Riley
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Elizabeth White
Rotations:
- Paul Bates
- Drew Weissman
- Elizabeth White
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Naiara Aquizu Lopez
Rotations:
- Naiara Aquizu Lopez
- Kiran Musunuru
- Beverly Davidson
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Drew Weissman
Rotations:
- John Wherry
- Drew Weissman
- Scott Hensley
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2015
Project Title: Characterizing the Physiological and Molecular Mechanism by Which hepatic Trib1 Regulates Plasma Lipids in Mice
Advisor(s):
- Daniel Rader
Rotations:
- Jean Bennett
- Daniel Rader
- Susan Weiss
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016
Project Title: Patient-derived HCV-like particle expressed by a lipid nanoparticle-encapsulated nucleoside-modified mRNA vaccine for HCV prophylaxis via bNAb elicitation
Advisor(s):
- Drew Weissman
- Katharine Bar
Rotations:
- David Weiner
- Drew Weissman
- Katharine Bar
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2015
Project Title: Ontogeny of HIV-1 V2 apex broadly neutralizing antibodies in SHIV-infected rhesus macaques
Advisor(s):
- George Shaw
Rotations:
- Luis Montaner
- George Shaw
- Erica Stone
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2014
Project Title: CRISPR-Cas9 Gene Editing Strategies of ATXN2 for the Treatment of Spinocerebellar Ataxia Type 2
Advisor(s):
- Beverly Davidson
Rotations:
- Jean Bennett
- Matthew Weitzman
- Beverly Davidson
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017
Project Title: Combining IAP Inhibitors with CAR-T Cell Therapy to Treat Glioblastoma
Advisor(s):
- Michael Milone
Rotations:
- Youhai Chen
- Michael Milone
- Nicola Mason
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017
Project Title: Functional Analysis of Triglyceride Regulator ApoA-V Using Naturally- Occurring Human Genetic Variants
Advisor(s):
- Daniel Rader
Rotations:
- Foteini Mourkioti
- Daniel Rader
- Kiran Musunuru
Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017
Project Title: Uncovering the role of CD38 in Acute Myeloid Leukemia
Advisor(s):
- Saar Gill
Rotations:
- Benjamin Prosser
- Carl June
- Saar Gill
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015
Project Title: Nuclear pore protein Megator attenuates dosage compensation of the male X chromosome
Advisor(s):
- Maya Capelson
Rotations:
- Maya Capelson
- David Raizen
- Mia Levine
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016
Advisor(s):
- Shelley Berger
Rotations:
- Roberto Bonasio
- Shelley Berger
- Marisa Bartolomei
My research revolves around nuclear acetyl-CoA metabolism and its contributions to histone acetylation and gene transcription in neurons. I am particularly interested in how the metabolic enzyme ACSS2 is recruited to the chromatin and how this recruitment impacts learning and memory in mice.
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Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Montserrat Anguera
Rotations:
- Montserrat Anguera
- Mary Mullins
- Foteini Mourkioti
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Zoltan Arany
Rotations:
- Rahul Kohli
- Zoltan Arany
- Joe Baur
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014
Project Title: Gnas inactivation alters adipose tissue properties during progression to heterotopic ossification
Advisor(s):
- Eileen Shore
Rotations:
- Katherine Nathanson
- Eileen Shore
- Benjamin Voight
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Struan Grant
- Christopher Brown
Rotations:
- Christopher Brown
- Klaus Kaestner
- Sarah Tishkoff
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015
Project Title: Investigating the roles of active DNA demethylation pathways in epigenetic reprogramming
Advisor(s):
- Marisa Bartolomei
Rotations:
- Marisa Bartolomei
- Thomas Jongens
- Mary Mullins
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016
Project Title: Roles of RNA-binding proteins and epigenetic regulators in acute myeloid leukemia
Advisor(s):
- Junwei Shi
Rotations:
- Jennifer Phillips-Cremins
- Gerd Blobel
- Junwei Shi
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016
Project Title: The Role of PAQR8 in Breast Cancer Metastasis and Therapy Resistance
Advisor(s):
- Lewis Chodosh
Rotations:
- Mitchell Lazar
- Lewis Chodosh
- Mark Kahn
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017
Advisor(s):
- Kathryn Hamilton
Rotations:
- Andy Minn
- Kathryn Hamilton
- Alessandro Gardini
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016
Project Title: Multiplexing CRISPR/Cas9-based Continuous Evolution for Improved Epigenome Editing
Advisor(s):
- Junwei Shi
- Rahul Kohli
Rotations:
- Kiran Musunuru
- Rahul Kohli
- Junwei Shi
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017
Project Title: Investigating the role of TRAK proteins as motor adaptors for mitochondrial transport in neurons
Advisor(s):
- Erika Holzbaur
- Thomas Jongens
Rotations:
- Roberto Bonasio
- Erika Holzbaur
- Thomas Jongens
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Mitchell Lazar
Rotations:
- Andy Minn
- Zhaolan Zhou
- Eric Joyce
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015
Project Title: Evaluating the role of genetic variation in the development of cardiometabolic disease
Advisor(s):
- Christopher Brown
- Benjamin Voight
Rotations:
- Maja Bucan
- Benjamin Voight
- Christopher Brown
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2015
Project Title:
Advisor(s):
- Zoltan Arany
Rotations:
- Zoltan Arany
- Ben Stanger
- Jennifer Phillips-Cremins
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Naiara Aquizu Lopez
Rotations:
- Jennifer Kalish
- Naiara Aquizu Lopez
- Erica Korb
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015
Advisor(s):
- Doris Stoffers
Rotations:
- Doris Stoffers
- Gerd Blobel
- David Raizen
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017
Project Title: Probing the three-dimensional organization of enhancer-promoter communication
Advisor(s):
- Douglas Epstein
- Eric Joyce
Rotations:
- Kenneth Zaret
- Douglas Epstein
- Eric Joyce
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Sydney Shaffer
Rotations:
- Sydney Shaffer
- Golnaz Vahedi
- Lukasz Bugaj
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018
Advisor(s):
- Alessandro Gardini
Rotations:
- Alessandro Gardini
- Gerd Blobel
- Roberto Bonasio
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017
Advisor(s):
- Eric Joyce
Rotations:
- Maya Capelson
- Eric Joyce
- Andres Blanco
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016
Project Title: Lineage Analysis of Cellular States Predicting Reprogramming into iPSCs
Advisor(s):
- Arjun Raj
Rotations:
- Arjun Raj
- Daniel Rader
- John Murray
Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2015
Project Title: Revealing the “primed” cellular states underlying variability in directed differentiation fates
Advisor(s):
- Arjun Raj
Rotations:
- Klaus Kaestner
- Golnaz Vahedi
- Arjun Raj
Genetics and Epigenetics
Degree: VMD/PhD
Matriculation Year: 2015
Project Title: The gut microbiota regulates the progression of obesity and white adipose tissue inflammation via a highly conserved family of microRNAs
Advisor(s):
- Jorge Henao-Mejia
Rotations:
- Montserrat Anguera
- Michael Silverman
- Jorge Henao-Mejia
Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017
Project Title: Investigating barriers to polygenic risk prediction across diverse populations
Advisor(s):
- Sarah Tishkoff
- Iain Mathieson
Rotations:
- Iain Mathieson
- Sarah Tishkoff
- Yana Kamberov