Current Students | Cell & Molecular Biology Graduate Group | Perelman School of Medicine at the University of Pennsylvania

Clayton Otter

Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2019

Rotations:

Rahul Kohli

Pierce Nathanson

Microbiology, Virology, and Parasitology
Degree: VMD/PhD
Matriculation Year: 2008

Advisor(s):

Alice Chen-Plotkin

Rotations:

Susan Weiss
Alice Chen-Plotkin
David Artis
Aaron Gitler

In the vast majority of cases of amyotrophic lateral sclerosis and ~50% of the cases of frontotemporal lobar degeneration, pathology is characterized by mislocalization and…Read More

Jayesh Tandel

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Understanding the transcriptome of sexual stages of Cryptosporidium parvum- an important prerequisite in unravelling the programming of the lifecycle of the parasite

Advisor(s):

Boris Striepen

Alexis Gibson

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Genome Wide CRISPR/Cas9 Knockout Screen Identifies Host Genes Important for Cryptosporidium parvum Infection

Advisor(s):

Boris Striepen

Kay Foos

Cancer Biology
Degree: VMD/PhD
Matriculation Year: 2019

Joshua Shaffer

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Kathryn Wellen
Peter Choi

Siera Rosen

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Edward Morrisey
Alex Hughes

Yohaniz Ortega-Burgos

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Elizabeth Bhoj
Paula Oliver

Ruchi Patel

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Andrei Thomas-Tikhonenko
Marco Ruella

Stefan Peterson

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Maayan Levy
Igor Brodsky

Brianne Roper

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Harvey Friedman
Audrey John

Elana Pyfrom

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

Marisa Bartolomei
Greg Bashaw

Jacqueline Plesset

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Ben Stanger
Celeste Simon

Ronit Schwartz

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Igor Brodsky
Elizabeth White

Olivia Pilling

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Michael Silverman
Daniel Beiting

Keenan O'Dea

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Sunny Shin
Christopher Hunter

Kara Nelson

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Jeremy Wang
Marisa Bartolomei

Daniel Morreale

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Joseph St Geme
Paul Planet

Erick Mitchell-Velasquez

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Maureen Murphy
Malay Haldar

Lydia Mendoza

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Scott Hensley
Matthew Weitzman

Kurtis McCannell

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

Mia Levine
Alessandro Gardini

Katherine Labella

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Thomas DeRaedt
Yael Mosse

Napasorn Kuprasertkul

Degree: MD/PhD
Matriculation Year: 2019

Kylie Konrath

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

Daniel Kulp
Norbert Pardi

Max Klapholz

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Andy Minn
Maayan Levy

Melissa Kim

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Panteleimon Rompolas
Andrew Vaughan

Valerie Irizarry-Negron

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Dmitry Gabrilovich
Ben Stanger

Caitlin Hopkins

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

Hamid Bassiri
Hansell Stedman

Kevin Hernandez

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Scott Hensley
Joseph Zackular

Rumi Habib

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Daniel Kulp
George Shaw

Adam Ferrari

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Constantinos Koumenis
Patrick Grohar

Ethan Fein

Degree: MD/PhD
Matriculation Year: 2019

Alejandra Fausto

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Kellie Jurado
Paul Bates

Stephen Carro

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Laurence Eisenlohr
Sara Cherry

Maria Carrera

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

Montserrat Anguera
Andres Blanco

Sarah Campbell

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

Naiara Aquizu Lopez
Greg Bashaw

Benjamin Caiello

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Bradley Johnson
Paul Lieberman

Shovik Bandyopadhyay

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

Ivan Maillard

June Yang

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Jianxin You

Rotations:

Jianxin You
Ronald Collman
Dennis Kolson

Vincent Wu

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Role of KLRG1 signaling on CD8+ T-cells during chronic HIV infection

Advisor(s):

Michael Betts

Rotations:

Frederic Bushman
Michael Betts
Elizabeth Grice

Ellen White

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

Elizabeth Grice

Rotations:

Elizabeth Grice
Michael Silverman

Monica Wei

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

Elizabeth Grice

Rotations:

Matthew Weitzman
Kai Tan
Elizabeth Grice

Louis Taylor

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Project Title: Replication and tropism of Redondoviridae, a new family of DNA viruses of the human oro-respiratory tract

Advisor(s):

Frederic Bushman

Rotations:

Frederic Bushman
Paula Oliver
Matthew Weitzman

Katherine Strelau

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Defining the proteins responsible for establishing C. parvum infection

Advisor(s):

Boris Striepen

Rotations:

Carolina Lopez
Boris Striepen
David Weiner

Gregory Sousa

Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2014

Advisor(s):

Michael Povelones

Rotations:

Matthew Hayes
Michael Povelones
De'Broski Herbert

Alexander Smith

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Joseph Zackular

Rotations:

James Riley
Joseph Zackular
Michael Silverman

Nawar Naseer

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Sunny Shin

Rotations:

Scott Hensley
Sunny Shin
Paul Planet

I am studying how the human immune system recognizes Salmonella, which causes diarrheal disease. Salmonella initially invades and replicates within intestinal epithelial cells by using…Read More

Victoria Lovins

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Elizabeth Grice

Rotations:

Elizabeth Grice
David Weiner
Carolina Lopez

Nadia Kadry

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Joseph St Geme

Rotations:

Joseph St Geme
Frederic Bushman
Ronald Collman

Philip Hicks

Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2016

Project Title: The role of retrograde trafficking during cellular entry by severe fever with thrombocytopenia syndrome virus

Advisor(s):

Paul Bates

Rotations:

Ronald Harty
Paul Bates
Elizabeth White

Beatrice Herrmann

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Igor Brodsky

Rotations:

Joseph St Geme
Igor Brodsky
Christoph Thaiss

Trevor Griesman

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Innate immunity in primary neurons: specialized responses to viral infection

Advisor(s):

Sara Cherry

Rotations:

Scott Hensley
Paul Bates
Sara Cherry

Lavinia Gonzalez

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Role of cytoplasmic stress granules during Respiratory Syncytial virus infection containing high levels of defective viral genomes

Advisor(s):

Carolina Lopez

Rotations:

Una O’Doherty
Carolina Lopez
Sara Cherry

James Gesualdi

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: The Blood Meningeal Barrier Orchestrates the Development of Autoimmune Neuroinflammatory Responses

Advisor(s):

Jorge Alvarez

Rotations:

Jorge Alvarez
Paul Lieberman
Katharine Bar

Jennifer Dumaine

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Cryptosporidium exports proteins to the cytoplasm of the epithelial host cell

Advisor(s):

Boris Striepen

Marcus Bolton

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Scott Hensley

Rotations:

George Shaw
Scott Hensley
David Allman

Anya Bauer

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Project Title: Development and Validation of SHIV-Macaque Models for HIV-1 Infection

Advisor(s):

Katharine Bar

Rotations:

Ronald Collman
Katharine Bar
James Riley

Antonia Bass

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Project Title: Elucidating the mechanisms underlying noncanonical inflammasome responses to Legionella pneumophila

Advisor(s):

Sunny Shin

Rotations:

Michael Povelones
Sunny Shin
Sara Cherry

Shannon Christensen

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Scott Hensley

Rotations:

Matthew Weitzman
Paul Bates
Susan Weiss
Scott Hensley

I will be studying antibody isotype, glycosylation status, and functionality in response to flavivirus and influenza infections.

Daniel Akuma

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Defining the Interaction between LPS and Caspase-11 in the Non-Canonical Inflammasome

Advisor(s):

Igor Brodsky

Rotations:

Igor Brodsky
Jianxin You
Michael Granato

Mary Margaret Addison

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Laurence Eisenlohr

Rotations:

Beatrice Hahn
Michael Betts
Laurence Eisenlohr

Despite HIV's significant global health importance, there is still much to learn about the ways in which the immune system detects and responds to this…Read More

Despite HIV's significant global health importance, there is still much to learn about the ways in which the immune system detects and responds to this virus. Robust HIV-specific CD4+ T cell responses are associated with decreased viral load and a slower progression to AIDS, and will likely be essential for generating protective HIV vaccine responses. However, CD4+ T cells must be activated before they can contribute to the immune response.
This activation requires the binding of T cell receptors on the surface of the CD4+ T cell to antigen-derived peptides (epitopes) displayed in complex with MHCII molecules (MHCII) on the surface of an antigen presenting cell (APC). Thus, understanding the cellular pathways responsible for the presentation of these pathogen-derived epitopes on MHCII is absolutely vital.
It was long thought that a single, classical pathway is responsible for MHCII antigen presentation. In this pathway, internalized antigens are catabolized and loaded onto MHCII in late endosomal compartments. However, this pathway is likely inadequate for the presentation of both cytosolic antigens and antigens derived from proteins that are not carried within the pathogen, such as certain viral accessory proteins. Notably, a non-canonical, endogenous processing pathway has also been shown to play a significant role in the presentation of pathogen-derived epitopes.
Endogenous processing occurs when virally-derived antigens synthesized within infected APCs are proteolyzed and loaded onto MHCII via a complex network of intracellular pathways. This pathway is better suited for the presentation of cytosolic and newly synthesized viral antigens.
Current literature addressing the cellular pathways used by APCs to activate
CD4+ T cells in response to HIV-1 is sparse and conflicting. While some
HIV-1 epitopes can be presented from inactivated virus, two HIV-1 epitopes have been shown to be presented exclusively endogenously. Thus, the relative contributions of the classical and endogenous pathways in HIV-1 antigen presentation are not known. Additionally, our understanding of the cell types that act as APCs during HIV-1 infection is incomplete, as it is unknown if CD4+ T cells themselves act as APCs during an HIV-1 infection.
In this study, I will determine the ability of human dendritic cells, macrophages, and CD4+ T cells to present HIV-1 epitopes from infectious and inactivated virus. I will also elucidate the cellular pathways used by dendritic cells to present the two endogenously produced HIV-1 peptides referenced above. These studies will shed light on the cellular pathways used by dendritic cells and macrophages to process and present HIV-1 epitopes, and will interrogate the antigen presenting capabilities of CD4+ T cells during HIV infection. I anticipate that data obtained from this project will reveal key insights regarding HIV host-pathogen interplay and may inform rational vaccine design.

Yeqiao Zhou

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: The Impact of Iron on Endolysosomal Function in the Retinal Pigment Epithelium

Advisor(s):

Robert Faryabi
Warren Pear

Rotations:

Warren Pear
Robert Faryabi
Golnaz Vahedi

Tammy Ying

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Rebecca Simmons

Rotations:

Peter Klein
Gerd Blobel
Rebecca Simmons
Roger Greenberg

During gestation, the fetus is highly susceptible to insults that will impact its later life. My thesis will elucidate the impact of intrauterine growth restriction…Read More

Daniel Xu

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Advisor(s):

Shelley Berger

Rotations:

Shelley Berger
Aimee Payne
Guo-Li Ming

Kevin Wiles

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Determining how axon guidance molecules regulate tissue homeostasis in the Drosophila intestinal epithelium

Advisor(s):

Greg Bashaw

Rotations:

Greg Bashaw
Christopher Brown
Roberto Bonasio

Brandon Wenz

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Christopher Brown

Rotations:

Christopher Brown
Raymond Soccio
Zhaolan Zhou

Bailey Warder

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Stephen Dinardo

Rotations:

Stephen Dinardo
Mary Mullins
Yana Kamberov

Aoi Wakabayashi

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Gerd Blobel

Rotations:

Gerd Blobel
Mitchell Lazar
Edward Morrisey

Increased levels of fetal hemoglobin (HbF) alleviates symptoms of beta hemoglobinopathies such as sickle cell disease. Therefore, it has been a long-standing interest in the…Read More

Gabriela Vida

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Stephen Dinardo

Rotations:

Meera Sundaram
Greg Bashaw
Stephen Dinardo

Natalie Toothacre

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Montserrat Anguera

Rotations:

Montserrat Anguera
Marisa Bartolomei
Irfan Asangani

Sabine Schneider

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2013

Project Title: Understanding the transcriptional regulation of enteric neuron subtype specification and differentiation

Advisor(s):

Robert Heuckeroth

Rotations:

Alice Chen-Plotkin
Robert Heuckeroth
Marcella Devoto

Alexandra Maldonado-Lopez

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Brian Capell

Rotations:

Brian Capell
Melike Lakadamyali
Fange Liu

Jennifer Luppino

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Project Title: Elucidating the role of chromatin architecture in the pathophysiology of Cornelia de Lange Syndrome

Advisor(s):

Eric Joyce

Rotations:

Alice Chen-Plotkin
Jennifer Phillips-Cremins
Eric Joyce

Jing Luan

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2014

Advisor(s):

Gerd Blobel

Rotations:

Paul Lieberman
Kenneth Zaret
Gerd Blobel

My thesis topic involves dissecting the roles and mechanisms of transcriptional pausing, and understanding the dynamics and mechanisms of chromatin organization during erythropoiesis.

Sheridan Littleton

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Struan Grant

Rotations:

Struan Grant
Ophir Shalem
Maja Bucan

Randi Isenhart

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Eric Joyce

Rotations:

Maya Capelson
Eric Joyce
Andres Blanco

Guillaume Harmange

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Sydney Shaffer

Rotations:

Sydney Shaffer
Golnaz Vahedi
Lukasz Bugaj

Jailynn Harke

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Probing the three-dimensional organization of enhancer-promoter communication

Advisor(s):

Douglas Epstein
Eric Joyce

Rotations:

Kenneth Zaret
Douglas Epstein
Eric Joyce

Matthew Haemmerle

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Doris Stoffers

Rotations:

Doris Stoffers
Gerd Blobel
David Raizen

Clarissa Guzman-Roman

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Maya Capelson

Rotations:

Kavitha Sarma
Maya Capelson
Kenneth Zaret

Charles Danan

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

Kathryn Hamilton

Rotations:

Andy Minn
Kathryn Hamilton
Alessandro Gardini

Jennifer Cohen

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014

Project Title: Apical extracellular matrix: Assembly and Function

Advisor(s):

Meera Sundaram

Rotations:

Mark Kahn
Benjamin Voight
Mary Mullins

Saisai Chen

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: The Role of PAQR8 in Breast Cancer Metastasis and Therapy Resistance

Advisor(s):

Lewis Chodosh

Rotations:

Mitchell Lazar
Lewis Chodosh
Mark Kahn

Zhendong Cao

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Project Title: Roles of RNA-binding proteins and epigenetic regulators in acute myeloid leukemia

Advisor(s):

Junwei Shi

Rotations:

Jennifer Phillips-Cremins
Gerd Blobel
Junwei Shi

Blake Caldwell

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Investigating the roles of active DNA demethylation pathways in epigenetic reprogramming

Advisor(s):

Marisa Bartolomei

Rotations:

Marisa Bartolomei
Thomas Jongens
Mary Mullins

Elizabeth Burton

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Struan Grant
Christopher Brown

Rotations:

Christopher Brown
Klaus Kaestner
Sarah Tishkoff

Niambi Brewer

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014

Project Title: Gnas inactivation alters adipose tissue properties during progression to heterotopic ossification

Advisor(s):

Eileen Shore

Rotations:

Katherine Nathanson
Eileen Shore
Benjamin Voight

Marc Bornstein

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

Zoltan Arany

Rotations:

Rahul Kohli
Zoltan Arany
Joe Baur

Zachary Beethem

Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Montserrat Anguera

Rotations:

Montserrat Anguera
Mary Mullins
Foteini Mourkioti

Melissa Barton

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Erica Korb

Rotations:

Naiara Aquizu Lopez
Edward Lee
Erica Korb

Anthony Angueira

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2014

Advisor(s):

Patrick Seale

Rotations:

Patrick Seale
Mitchell Lazar
Harry Ischiropoulos

I will utilize mouse genetics and metabolic assays to determine how BAT blood flow is regulated uponcold exposure. In particular, I will focus on the…Read More

Kimberly Veliz

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: Uncovering the role of CD38 in Acute Myeloid Leukemia

Advisor(s):

Saar Gill

Rotations:

Benjamin Prosser
Carl June
Saar Gill

Lucas Van Gorder

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Harnessing PRPF31 as a Gene Therapy Target Utilizing an IPSC Model

Advisor(s):

Jean Bennett

Rotations:

Jean Bennett
Kar Muthumani
Valder Arruda

Sylvia Stankov

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: Functional Analysis of Triglyceride Regulator ApoA-V Using Naturally- Occurring Human Genetic Variants

Advisor(s):

Daniel Rader

Rotations:

Foteini Mourkioti
Daniel Rader
Kiran Musunuru

Zeyuan Edward Song

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: Combining IAP Inhibitors with CAR-T Cell Therapy to Treat Glioblastoma

Advisor(s):

Michael Milone

Rotations:

Youhai Chen
Michael Milone
Nicola Mason

Bryan Simpson

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2014

Project Title: CRISPR-Cas9 Gene Editing Strategies of ATXN2 for the Treatment of Spinocerebellar Ataxia Type 2

Advisor(s):

Beverly Davidson

Rotations:

Jean Bennett
Matthew Weitzman
Beverly Davidson

Jesse Rodriguez

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2012

Project Title: Re-directing cytomegalovirus specific chimeric antigen receptor T cells for glioblastoma multiforme cancer immunotherapy.

Advisor(s):

Carl June
Laura Johnson

Rotations:

Valder Arruda
Matthew Weitzman
Nicola Mason
Gregory Beatty
Carl June

Ryan Roark

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2015

Project Title: Ontogeny of HIV-1 V2 apex broadly neutralizing antibodies in SHIV-infected rhesus macaques

Advisor(s):

George Shaw

Rotations:

Luis Montaner
George Shaw
Erica Stone

Erin Reagan

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Patient-derived HCV-like particle expressed by a lipid nanoparticle-encapsulated nucleoside-modified mRNA vaccine for HCV prophylaxis via bNAb elicitation

Advisor(s):

Drew Weissman
Katharine Bar

Rotations:

David Weiner
Drew Weissman
Katharine Bar

Laura Ohl

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Naiara Aquizu Lopez

Rotations:

Naiara Aquizu Lopez
Kiran Musunuru
Beverly Davidson

Leon Morales

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2014

Project Title: Assessing the Safety and Efficacy of a Gene Transfer Approach for Duchenne Muscular Dystrophy

Advisor(s):

Hansell Stedman
Jean Bennett

Rotations:

Valder Arruda
Hansell Stedman
Jean Bennett

Jacob Hoffman

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

James Wilson

Rotations:

Kiran Musunuru
Stefano Rivella
James Wilson

Maxwell Chappell

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Lentiviral Vectors as Therapeutic Options for the Treatment of Alpha-Thalassemia

Advisor(s):

Stefano Rivella

Rotations:

Valder Arruda
Stefano Rivella
John Wolfe

Kimberly Apodaca

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Beatriz Carreno
Gerald Linette

Rotations:

Katharine Bar
Jan Melenhorst
Gerald Linette
Beatriz Carreno

Kevin Alicea-Torres

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2014

Project Title: Role of IFNAR1 in the immune suppression by PMN-MDSCs in cancer

Advisor(s):

Dmitry Gabrilovich

Rotations:

Gregory Beatty
Celeste Simon
Dmitry Gabrilovich

Karen Wong

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Determining the role of H3K9me2S10 phosphorylation in peripheral heterochromatin localization

Advisor(s):

Jonathan Epstein

Rotations:

Jonathan Epstein
Mark Kahn
Melike Lakadamyali

Ian Penkala

Developmental, Stem Cell and Regenerative Biology
Degree: VMD/PhD
Matriculation Year: 2014

Advisor(s):

Edward Morrisey

Rotations:

Ben Stanger
Edward Morrisey
Christopher Lengner

My thesis is focused on studying the developmental ontogeny and maturation process of alveolar type one cells in the lung.

Sarshan Pather

Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2016

Advisor(s):

Hongjun Song

Rotations:

Rajan Jain
Hongjun Song
Guo-Li Ming
D. Kacy Cullen
Jonathan Epstein

Christopher Pai

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Robert Heuckeroth

Rotations:

Montserrat Anguera
Robert Heuckeroth
Mia Levine

I'm studying the role of microRNAs in the development of the enteric nervous system.

Somdutta Mukherjee

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Project Title: Investigating the Role of TBX3 in Human Endoderm Development

Advisor(s):

Paul Gadue

Rotations:

Paul Gadue
John Murray
Warren Pear

Nicolette Johnson

Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2015

Advisor(s):

Christopher Lengner

Rotations:

Thomas Leung
Katalin Susztak
Rebecca Wells

Allison Jamieson-Lucy

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2012

Advisor(s):

Mary Mullins

Rotations:

Erfei Bi
Mary Mullins
Edward Morrisey

The Balbiani body (Bb) is a transient aggregate found within the oocytes of many species, conserved form insects to humans. It shares structural similarities with…Read More

Elizabeth Howell

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Identifying necessary chromatin states and targets for hemogenic specification and reprogramming by the transcription factor Runx1

Advisor(s):

Nancy Speck

Rotations:

Peter Klein
Nancy Speck
Klaus Kaestner

Christopher Greer

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Comparative phylogenetics of the dystrophin associated protein complex protein families and implications for Adeno-associated virus (AAV)-mediated gene therapy in Duchenne muscular dystrophy.

Advisor(s):

Hansell Stedman

Rotations:

Jonathan Epstein
Foteini Mourkioti
Jason Burdick
Hansell Stedman

Hannah Greenfeld

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Interpretation of the BMP morphogen gradient patterning the dorsal-ventral axis of the zebrafish embryo

Advisor(s):

Mary Mullins

Rotations:

Patrick Seale
Mary Mullins
Greg Bashaw

A gradient of BMP signaling activity patterns the dorsoventral embryonic axis of all vertebrates. My project seeks the mechanism by which cells interpret different levels…Read More

Elizabeth Gallagher

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Erika Holzbaur

Rotations:

Erika Holzbaur
Greg Bashaw
Matthew Good

Ioana Soaita

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Zoltan Arany

Rotations:

Elizabeth Grice
Zoltan Arany
Raymond Soccio

Jessica Phan

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Edward Lee

Rotations:

Kelly Jordan-Sciutto
Edward Lee
Robert Kalb

Michael Neinast

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Zoltan Arany

Rotations:

Benjamin Prosser
Zoltan Arany
Joe Baur

I am studying branched-chain amino acid (BCAA) metabolism and how it changes with obesity. BCAAs worsen insulin resistance but the mechanism is controversial. Many proposed mechanisms hinge on changes…Read More

Danielle Murashige

Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2014

Advisor(s):

Zoltan Arany

Rotations:

Zoltan Arany
Hao Wu
Adam Resnick

Quentin McAfee

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Zoltan Arany

Rotations:

Michael Marks
Benjamin Prosser
Zoltan Arany

Yaoyu Gong

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Project Title: Enhancing antitumor cytotoxicity of natural killer cells by increasing their intracellular pH

Advisor(s):

Chi Dang

Rotations:

Chi Dang
Mitchell Lazar
Celeste Simon

Clark Fritsch

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Yale Goldman

Rotations:

Marc Vermulst
Rugang Zhang
Edward Lee
Ronen Marmorstein

Emily Flam

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Zoltan Arany

Rotations:

Zoltan Arany
Benjamin Prosser
Kenneth Margulies

Emily Fernandez Garcia

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014

Project Title: Targeting Calcium Signaling from the Endoplasmic Reticulum to Mitochondria for the Development of New Chemotherapies

Advisor(s):

Kevin Foskett

Rotations:

Kevin Foskett
Erika Holzbaur
Robert Kalb

As a dissertation student my thesis project aims to understand how genetic and pharmacological inhibition of calcium influx into mitochondria, as well as inhibition of…Read More

Lisa Cucolo

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2013

Project Title: Tumor RIPK1 Signaling Mediates Intrinsic and Extrinsic Mechanisms of Resistance to Immune Checkpoint Blockade Therapy

Advisor(s):

Andy Minn

Rotations:

Kathryn Wellen
Mitchell Lazar
Andy Minn
Dwight Gilliland

Allison Cote

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2012

Advisor(s):

Arjun Raj

Rotations:

Rebecca Wells
Janis Burkhardt
Arjun Raj

Expansion microscopy is a technique that involves the use of a swellable polymer network to physically expand the specimen of interest and physically separate points…Read More

Stephen Coscia

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Project Title: A mechanistic investigation into F-actin assembly on mitochondria as a wave

Advisor(s):

Erika Holzbaur

Rotations:

Erika Holzbaur
Michael Ostap
James Shorter

Jessica Chotiner

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Project Title: Cyclin B3 is an essential factor in female fertility and embryonic development

Advisor(s):

Jeremy Wang

Rotations:

Jeremy Wang
Yana Kamberov
Marisa Bartolomei

Salina Yuan

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2013

Project Title: Epigenetic mechanisms regulating epithelial plasticity in pancreatic ductal adenocarcinoma

Advisor(s):

Ben Stanger

Rotations:

Ben Stanger
Kathryn Wellen
Donita Brady

Sixiang Yu

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Xiaolu Yang

Rotations:

Shelley Berger
Xiaolu Yang
Gerd Blobel

Darwin Ye

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Pattern recognition receptor signaling in immune checkpoint blockade resistance

Advisor(s):

Andy Minn

Rotations:

Andy Minn
Junwei Shi
Shelley Berger

Fangxue (Yumi) Yan

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: The role of Epigenetic Regulators in Restricting LSD1i-Mediated Differentiation in Acute Myeloid Leukemia

Advisor(s):

Andres Blanco

Rotations:

Ben Stanger
David Feldser
Andres Blanco

David Walter

Cancer Biology
Degree: PhD
Matriculation Year: 2013

Project Title: Elucidating the tumor suppressive functions of Rb and Setd2 in lung adenocarcinoma

Advisor(s):

David Feldser

Rotations:

David Feldser
James Riley
Xiaolu Yang

Tiffany Tsang

Cancer Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Paradoxical YAP activation as an emergent limitation to Cu chelation therapy in BRAFV600E-driven melanoma

Advisor(s):

Donita Brady

Rotations:

Donita Brady
Kathryn Wellen
Constantinos Koumenis

Jinyang Li

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Investigating tumor cell-intrinsic factors regulating immune infiltration in pancreatic cancer

Advisor(s):

Ben Stanger

Rotations:

Ben Stanger
Lewis Chodosh
Kathryn Wellen

Jesse Lee

Cancer Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Gregory Beatty

Rotations:

John Maris
Saar Gill
Gregory Beatty

In Young Lee

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Understanding and Overcoming Melanoma Resistance to GPCR-based Therapy

Advisor(s):

Todd Ridky

Rotations:

David Feldser
Todd Ridky
Gerald Linette

Avery Lee

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating the Roles of Activation-Induced Cytidine Deaminase in theMalignant Progression of Chronic Lymphocytic Leukemia

Advisor(s):

Andrew Hu

Rotations:

Tzipora Sarah Karin Eisinger
Andrew Hu
Oliver Garden

Linh Le

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Investigating the mechanisms underlying melanosome biogenesis and maturation

Advisor(s):

Michael Marks

Rotations:

Andrei Thomas-Tikhonenko
Rugang Zhang
Michael Marks
Patrick Viatour

Claudia Lanauze

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Andrei Thomas-Tikhonenko

Rotations:

Andrei Thomas-Tikhonenko
Nancy Speck
Xianxin Hua

Piotr Kopinski

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2011

Project Title: Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy

Advisor(s):

Douglas Wallace

Rotations:

Jean Bennett
Douglas Wallace
Shelley Berger

Priya Khurana

Cancer Biology
Degree: PhD
Matriculation Year: 2015

Project Title: Investigating the immunometabolism and anti-tumor properties of invariant natural killer T (iNKT) cells in neuroblastoma

Advisor(s):

Hamid Bassiri

Rotations:

Roger Greenberg
Maureen Murphy
Hamid Bassiri

Sanika Khare

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Celeste Simon

Rotations:

Warren Pear
Mitchell Lazar
Celeste Simon

My thesis topic is investigating the role of urea cycle enzymes in clear cell renal cell carcinoma (ccRCC) progression. We observe reduction in the levels…Read More

Kanika Jain

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Margaret Chou

Rotations:

Andy Minn
Saar Gill
Dmitry Gabrilovich
Gregory Beatty

Luke Izzo

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating the role of ACLY and acetyl-CoA metabolism in hepatocellular carcinoma

Advisor(s):

Kathryn Wellen

Rotations:

Kathryn Wellen
Wei Tong
Martin Carroll

Yinghui (Jane) Huang

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Role of HMG-box transcription factor TOX in maintaining CD8 T cell exhaustion

Advisor(s):

John Wherry

Rotations:

Dmitry Gabrilovich
Jorge Henao-Mejia
John Wherry

Rebecca Glynn

Cancer Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Defining the Mechanism and Function of DNA Double Strand Break Induced Inhibition of V(D)J Recombination

Advisor(s):

Craig Bassing

Rotations:

John Maris
Ronny Drapkin
Craig Bassing

Ian Folkert

Cancer Biology
Degree: PhD
Matriculation Year: 2016

Project Title: The Role of the Endothelin B Receptor in Macrophage Function

Advisor(s):

Malay Haldar

Rotations:

Ben Stanger
Anil Rustgi
Malay Haldar

Jorida Coku

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Elucidating mechanisms of cancer therapy resistance due to alterations in endoplasmic reticulum-mitochondria contact sites

Advisor(s):

Michael Hogarty

Rotations:

Vera Krymskaya
Michael Hogarty
Rugang Zhang

Zeyu Chen

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Dissecting transcriptional network during CD8+ T cell response

Advisor(s):

John Wherry

Rotations:

David Feldser
John Wherry
Mitchell Lazar

Sydney Campbell

Cancer Biology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Kathryn Wellen

Rotations:

Kathryn Wellen
Celeste Simon
Shelley Berger

My thesis is focused on understanding the functional impacts of changes in flux through the hexosamine biosynthesis pathway in pancreatic cancer.

Rebekah Brooks

Cancer Biology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Chi Dang

Rotations:

Donita Brady
Celeste Simon
Chi Dang

I am currently working on determining the function of a previously uncharacterized circadian oscillating long noncoding RNA (lncRNA) that may modulate the degradation of an…Read More

Brian Benz

Cancer Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Lewis Chodosh

Rotations:

Wei Tong
Todd Ridky
Lewis Chodosh

Vivek Behera

Cancer Biology
Degree: MD/PhD
Matriculation Year: 2011

Project Title: MINING THE SPATIAL AND TEMPORAL CONTEXT BY WHICH TRANSCRIPTION FACTORS OCCUPY CHROMATIN

Advisor(s):

Gerd Blobel

Rotations:

Gerd Blobel
Kristen Lynch
Roger Greenberg

Keren Adler

Cancer Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

David Feldser

Rotations:

Sandra Ryeom
Ben Stanger
David Feldser

Jonuelle Acosta

Cancer Biology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

David Feldser

Rotations:

David Feldser
Kristen Lynch
Donita Brady

The tumor suppressor p53 can transactivate genes that mediate cytostatic and cytotoxic anti-tumor responses in a context-dependent manner. However, it is not known exactly how…Read More

Jayme Nordin

Developmental, Stem Cell, and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Zhaolan Zhou
Lewis Chodosh

Raymond Ng

Degree: MD/PhD
Matriculation Year: 2019

Catriana Nations

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Paul Gadue
Stewart Anderson

Kelly Martins

Gene Therapy and Vaccines
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

James Wilson

Rotations:

Kiran Musunuru
James Wilson

Emily Lubin

Degree: MD/PhD
Matriculation Year: 2019

Claudia Lovell

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

Kathryn Wellen

Jingxin (Jessica) Li

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018

Advisor(s):

Arjun Raj

Rotations:

Mitchell Lazar
Arjun Raj

Elisabeth Lemmon

Developmental, Stem Cell, and Regenerative Biology
Degree: VMD/PhD
Matriculation Year: 2018

Rotations:

Robert Mauck

Amanda Lee

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Andy Minn
Marco Ruella
Peter Choi

Andrew Katznelson

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

Gerd Blobel
Kenneth Zaret

Nathan Katz

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

Daniel Rader

Benjamin Kahn

Degree: MD/PhD
Matriculation Year: 2019

Yanqing (Christine) Jiang

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Celeste Simon
Ben Stanger

Michaela Helble

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

Daniel Powell
Michael Mitchell

Nicholas Grams

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Dieter Schifferli
Matthew Weitzman
Paul Lieberman

Brian Goldspiel

Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

Carolina Lopez
Will Bailis

Amy Gladstein

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

Brian Capell
Nancy Bonini

Zachary Gardner

Degree: MD/PhD
Matriculation Year: 2019

Brian Franklin

Degree: MD/PhD
Matriculation Year: 2019

Annabel Ferguson

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Sara Cherry
Michaela Locci

Katherine Doerig

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

David Feldser

Perry Demsko

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

Michael Milone
Saar Gill
Stefano Rivella

Patricia Colosi

Cell Biology, Physiology, and Metabolism
Degree: PhD
Matriculation Year: 2019

Rotations:

Meera Sundaram
Melike Lakadamyali

Ian Cohn

Microbiology, Virology, and Parasitology
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

Scott Hensley

Nathan Coffey

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2018

Rotations:

Katalin Susztak

Julia Chini

Degree: MD/PhD
Matriculation Year: 2019

Roderick (Ricky) Brathwaite

Cancer Biology
Degree: PhD
Matriculation Year: 2019

Rotations:

Lewis Chodosh
Todd Ridky

Charles Bond

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2019

Rotations:

Melike Lakadamyali
Erika Holzbaur

Nicholas Bolden

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Paula Oliver
Mark Goulian

Ryan Boe

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

Arjun Raj

Rotations:

Jennifer Phillips-Cremins
Arjun Raj

Nicholas Aboreden

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2019

Rotations:

Junwei Shi
Gerd Blobel

Jenna Zhang

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

Sunny Shin
Igor Brodsky

Rotations:

Sunny Shin
Joseph Zackular

Alice Sukhina

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Will Bailis

Rotations:

Christopher Hunter
Warren Pear
Will Bailis

Ariel Shepley-McTaggart

Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2018

Project Title: The Ups and Downs of Host Regulation of Ebola Hemorrhagic Fever Virus Egress

Advisor(s):

Ronald Harty

Rotations:

Beatrice Hahn
Matthew Weitzman
Ronald Harty

Elisha Segrist

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Project Title: Investigating the Role of STING during enteric RNA virus infection in Drosophila

Advisor(s):

Sara Cherry

Rotations:

Sara Cherry
Harvey Friedman
Laurence Eisenlohr

Prioty Sarwar

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Paul Planet

Rotations:

Paul Planet
Dustin Brisson

Ronnie Russell

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Beatrice Hahn

Rotations:

Una O’Doherty
George Shaw
Beatrice Hahn

My thesis research is focused on the role of type 1 interferon on the evolution of HIV-1. This includes studying the ways in which SIVcpz…Read More

David Renner

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Susan Weiss

Rotations:

Matthew Weitzman
Susan Weiss
Kristen Lynch

Tzvi Pollock

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Project Title: Determining the Mechanism of TNF-Mediated Defense Against Intracellular Legionella pneumophila Infection

Advisor(s):

Sunny Shin

Rotations:

Phillip Scott
Michael Povelones
Sunny Shin

Alexandra Perry

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Joseph St Geme

Rotations:

Joseph St Geme
Kimberly Gallagher
Mechthild Pohlschroder

Elise Peauroi

Microbiology, Virology and Parasitology
Degree: VMD/PhD
Matriculation Year: 2015

Project Title: Investigating the innate immune antagonistic effects of the multifunctional C15 protein of Ectromelia virus

Advisor(s):

Laurence Eisenlohr

Rotations:

Matthew Weitzman
Scott Hensley
Laurence Eisenlohr

Son Nguyen

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

James Hoxie
Michael Betts

Rotations:

James Hoxie
Michael Betts
Laura Su

Kalyani Nambiar

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2014

Project Title: Isolation and Characterization of Novel Adeno-associated Viruses from Mammalian Hosts; Development of Vectors for Gene Therapy

Advisor(s):

James Wilson

Rotations:

Luis Montaner
James Wilson
Matthew Weitzman

Daniel Morris

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

George Shaw

Rotations:

George Shaw
Katharine Bar
Michael Betts

Nina Montoya

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Defining capsule and exopolysaccharide-independent complement resistance factors in Kingella kingae

Advisor(s):

Joseph St Geme

Rotations:

Elizabeth White
Laurence Eisenlohr
Joseph St Geme

Rina Matsuda

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: Role of Yersinia pseudotuberculosis virulence in granuloma formation during intestinal infection

Advisor(s):

Igor Brodsky

Rotations:

Igor Brodsky
Boris Striepen
Michael Abt

Kaitlin Marquis

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Frederic Bushman

Rotations:

Susan Weiss
Sara Cherry
Frederic Bushman

Tomaz Manzoni

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Project Title: Identifying reservoir cells of persistently infecting Sendai virus in vivo

Advisor(s):

Paul Bates

Rotations:

Carolina Lopez
Laurence Eisenlohr
Paul Bates

Natasha Lopes Fischer

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Project Title: Evasion of Human Innate Immunity by Coxiella burnetii

Advisor(s):

Sunny Shin

Rotations:

Michael Betts
Sunny Shin
Paul Planet

Valerie Linck

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Ronald Collman

Rotations:

Ronald Harty
Jianxin You
Ronald Collman

Nathan Krump

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2016

Project Title: Dissecting the Immune Response to Merkel Cell Polyomavirus Infection

Advisor(s):

Jianxin You

Rotations:

Matthew Weitzman
Jianxin You
Igor Brodsky

Joshua Hatterschide

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Project Title: The role of PTPN14 inactivation by HPV E7 in the differentiation-dependent HPV life cycle

Advisor(s):

Elizabeth White

Rotations:

Carolina Lopez
Elizabeth White
Susan Weiss

Christopher Gu

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Frederic Bushman

Rotations:

Frederic Bushman
Elizabeth Grice
Scott Hensley

Emmanuelle Genoyer

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Carolina Lopez

Rotations:

Jianxin You
Carolina Lopez
Susan Weiss

Defective viral genomes of paramyxoviruses, the initial triggers of antiviral immunity during infection, are localized discretely from full-length viral genomes in the context of infection.…Read More

Devin Fisher

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Carolina Lopez

Rotations:

Hao Shen
David Weiner
Carolina Lopez

My project is examining the mechanism of recognition of defective viral genomes (DVGs) during paramyxovirus infections in vivo. Additionally, I will be examining the mechanism…Read More

Grant Eilers

Microbiology, Virology and Parasitology
Degree: MD/PhD
Matriculation Year: 2014

Project Title: Structural Studies of Antiretroviral Drugs Targeting HIV Integrase

Advisor(s):

Frederic Bushman
Gregory Van Duyne

Rotations:

Frederic Bushman
Katharine Bar
Gregory Van Duyne

I will be studying HIV integrase. Multimeric forms of integrase are the target of two classes of antiretroviral therapy, the strand transfer inhibitors and the…Read More

Marisa Egan

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Sunny Shin

Rotations:

Jun Zhu
Sunny Shin
Mark Goulian

Emily Cribas

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Michael Abt

Rotations:

Michael Abt
Gary Wu
Jun Zhu

Courtney Comar

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Susan Weiss

Rotations:

Paul Bates
Susan Weiss
Carolina Lopez

My thesis project will focus on Middle East respiratory syndrome coronavirus (MERS-CoV) interactions with the human host innate immune system. MERS-CoV encodes a small, dsRNA…Read More

Clare Cimperman

Microbiology, Virology and Parasitology
Degree: PhD
Matriculation Year: 2019

Rotations:

Elizabeth White
Scott Hensley

Pankhuri Singhal

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Improved prediction modeling of complex genetic disease with multiomic data integration using knowledge-based variable selection

Advisor(s):

Marylyn Ritchie

Rotations:

Christopher Brown
Rui Feng
Marylyn Ritchie

Stephanie Sansbury

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Ophir Shalem

Rotations:

Sarah Tishkoff
Golnaz Vahedi
Ophir Shalem

Sean Ryan

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Kelly Jordan-Sciutto
Stewart Anderson

Rotations:

Nancy Bonini
Stewart Anderson
Peter Klein

I am studying the role of the complement cascade and sex differences in HIV-mediated neurotoxicity, which leads to development of HIV-Associated Neurocognitive Disorders. I am…Read More

Jonathan Rumley

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2013

Project Title: Regulation of anterior genes in the C. elegans embryo

Advisor(s):

John Murray

Rotations:

Dwight Stambolian
Maya Capelson
John Murray

Caleb Radens

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Alternative Splicing Variations in T cells and B-ALL

Advisor(s):

Yoseph Barash
Kristen Lynch

Rotations:

Christopher Brown
Benjamin Voight
Kristen Lynch
Yoseph Barash

Wenchao Qian

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Regulation of Genome Activation and Contribution of a Spatial Pattern of Zygotic Transcription in Vertebrate Early Embryo Development

Advisor(s):

Matthew Good

Rotations:

Hao Wu
Kenneth Zaret
Gerd Blobel
Melike Lakadamyali

Sai Phyo

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2015

Advisor(s):

Benjamin Prosser

Rotations:

Roger Greenberg
Kenneth Zaret
Gerd Blobel
Jennifer Phillips-Cremins

Ana Petracovici

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Project Title: Dissecting the roles of Polycomb Repressive 2 accessory subunits during early developmental transitions

Advisor(s):

Roberto Bonasio

Rotations:

Hao Wu
Roberto Bonasio
Alessandro Gardini

Felicia Peng

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

John Murray

Rotations:

John Murray
Maya Capelson
Doris Wagner

Daniel Park

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Investigating the role of chromosome architecture in the pathophysiology of Cornelia de Lange Syndrome

Advisor(s):

Eric Joyce

Rotations:

Jennifer Phillips-Cremins
Eric Joyce
Edward Lee

Gina Pacella

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Brian Capell

Rotations:

Brian Capell
Golnaz Vahedi
Elizabeth Heller

Alexis Oguh

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Doris Stoffers

Rotations:

Zhaolan Zhou
Doris Stoffers
Ophir Shalem

Sarah Offley

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Alessandro Gardini

Rotations:

Alessandro Gardini
John Murray
Shawn Little

Emily O'Driscoll

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating Proteolytic Cleavage Events Using Genome-Wide CRISPR/Cas9 Knockout Screens

Advisor(s):

Ophir Shalem

Rotations:

Ophir Shalem
Nancy Bonini
Edward Lee

Mailyn Nishiguchi

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Edward Behrens

Rotations:

Todd Ridky
Panteleimon Rompolas
Thomas Leung

Ricardo Linares Saldana

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2014

Advisor(s):

Rajan Jain
Jonathan Epstein

Rotations:

Edward Lee
Rajan Jain
Ben Black

My work focuses on elucidating mechanisms by which multipotent cardiac progenitors make cell fate decisions during cardiac specification. More specifically, I am defining the role…Read More

Marianne Kramer

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2014

Project Title: Understanding the role of post-transcriptional gene regulation and long non-coding RNAs during plant stress and development

Advisor(s):

Brian Gregory

Rotations:

Montserrat Anguera
Brian Gregory
Jeremy Wilusz

Ayano Kondo

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Project Title: Role of Foxl1+ mesenchymal cell-derived Wnt5a during intestinal development

Advisor(s):

Klaus Kaestner

Rotations:

Zachary Schug
Klaus Kaestner
Katalin Susztak

Karun Kiani

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Inducing transcriptional reprogramming with targeted chemotherapy

Advisor(s):

Arjun Raj

Rotations:

Erika Holzbaur
Arjun Raj
Golnaz Vahedi

Ashley Karnay

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Rajan Jain

Rotations:

Rajan Jain
Andres Blanco
Eric Joyce

Kelsey Kaeding

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Basis for specificity in heterochromatin establishment by zinc finger transcription factors

Advisor(s):

Kenneth Zaret

Rotations:

Kenneth Zaret
Golnaz Vahedi
Christopher Brown

My thesis project is about understanding the role that zinc finger proteins play in regulating cell type specific heterochromatin. This will be studied in the…Read More

Dan Ju

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating barriers to polygenic risk prediction across diverse populations

Advisor(s):

Sarah Tishkoff
Iain Mathieson

Rotations:

Iain Mathieson
Sarah Tishkoff
Yana Kamberov

Monica Jimenez

Genetics and Epigenetics
Degree: VMD/PhD
Matriculation Year: 2015

Project Title: The gut microbiota regulates the progression of obesity and white adipose tissue inflammation via a highly conserved family of microRNAs

Advisor(s):

Jorge Henao-Mejia

Rotations:

Montserrat Anguera
Michael Silverman
Jorge Henao-Mejia

Connie Jiang

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2015

Project Title: Revealing the molecular underpinnings of transcriptional heterogeneity

Advisor(s):

Arjun Raj

Rotations:

Klaus Kaestner
Golnaz Vahedi
Arjun Raj

Naveen Jain

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Lineage Analysis of Cellular States Predicting Reprogramming into iPSCs

Advisor(s):

Arjun Raj

Rotations:

Arjun Raj
Daniel Rader
John Murray

Connor Hill

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Alessandro Gardini

Rotations:

Alessandro Gardini
Gerd Blobel
Roberto Bonasio

Carolina Gracia Diaz

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Naiara Aquizu Lopez

Rotations:

Jennifer Kalish
Naiara Aquizu Lopez
Erica Korb

Bridget Gosis

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2015

Project Title:

Advisor(s):

Zoltan Arany

Rotations:

Zoltan Arany
Ben Stanger
Jennifer Phillips-Cremins

Katerina Gawronski

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Evaluating the role of genetic variation in the development of cardiometabolic disease

Advisor(s):

Christopher Brown
Benjamin Voight

Rotations:

Maja Bucan
Benjamin Voight
Christopher Brown

Yee Hoon Foong

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Mitchell Lazar

Rotations:

Andy Minn
Zhaolan Zhou
Eric Joyce

Adam Fenton

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2017

Project Title: Investigating the role of TRAK proteins as motor adaptors for mitochondrial transport in neurons

Advisor(s):

Erika Holzbaur
Thomas Jongens

Rotations:

Roberto Bonasio
Erika Holzbaur
Thomas Jongens

Niklaus Evitt

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Multiplexing CRISPR/Cas9-based Continuous Evolution for Improved Epigenome Editing

Advisor(s):

Junwei Shi
Rahul Kohli

Rotations:

Kiran Musunuru
Rahul Kohli
Junwei Shi

Hoang Bui Nguyen

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2016

Project Title: Dichotomous Engagement of HDAC3 Catalytic Activity Governs Inflammatory Responses

Advisor(s):

Mitchell Lazar

Rotations:

Andy Minn
Mitchell Lazar

Desiree Alexander

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Shelley Berger

Rotations:

Roberto Bonasio
Shelley Berger
Marisa Bartolomei

My research revolves around nuclear acetyl-CoA metabolism and its contributions to histone acetylation and gene transcription in neurons. I am particularly interested in how the…Read More

Jennifer Aleman

Genetics and Epigenetics
Degree: PhD
Matriculation Year: 2015

Project Title: Nuclear pore protein Megator attenuates dosage compensation of the male X chromosome

Advisor(s):

Maya Capelson

Rotations:

Maya Capelson
David Raizen
Mia Levine

Katherine Quiroz-Figueroa

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2015

Project Title: Characterizing the Physiological and Molecular Mechanism by Which hepatic Trib1 Regulates Plasma Lipids in Mice

Advisor(s):

Daniel Rader

Rotations:

Jean Bennett
Daniel Rader
Susan Weiss

Matthew Pine

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Drew Weissman

Rotations:

John Wherry
Drew Weissman
Scott Hensley

Joangela Nouel

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Elizabeth White

Rotations:

Paul Bates
Drew Weissman
Elizabeth White

Julia Noll

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2019

Rotations:

Michael Milone
Joseph Fraietta
James Riley

Richard (Alex) Martino

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Understanding the Mechanisms of PHP.B Transport Across the Murine Blood-Brain Barrier

Advisor(s):

James Wilson

Rotations:

Kiran Musunuru
James Wilson
Jeffrey Saven

Colby Maldini

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2015

Advisor(s):

James Riley

Rotations:

Michael Betts
James Riley
John Wherry

Suying Liu

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: The role of a gut microbiota-induced lncRNA in regulating intestinal epithelial cells

Advisor(s):

Jorge Henao-Mejia

Rotations:

Junwei Shi
Aimee Payne
Jorge Henao-Mejia

Jonathan Lang

Gene Therapy and Vaccines
Degree: MD/PhD
Matriculation Year: 2014

Project Title: Mechanisms of adeno-associated virus (AAV) transduction and AAV-mediated gene editing

Advisor(s):

Beverly Davidson

Rotations:

Beverly Davidson
Amita Sehgal
Drew Weissman

Coral Kasden

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Hansell Stedman

Rotations:

Joshua Dunaief
Hansell Stedman
Daniel Rader

Inyoung (Ethan) Jung

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Joseph Fraietta

Rotations:

Jan Melenhorst
Joseph Fraietta
Shelley Berger

Jeremy Grevet

Genetics and Epigenetics
Degree: MD/PhD
Matriculation Year: 2011

Project Title: Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.

Advisor(s):

Gerd Blobel

Rotations:

Gerd Blobel
Edward Morrisey
Ben Garcia

Kelly Fagan

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Beverly Davidson

Rotations:

John Wolfe
Beverly Davidson
Stefano Rivella

McKensie Collins

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Understanding CAR T cell Dysfunction in Chronic Lymphocytic Leukemia

Advisor(s):

Jan Melenhorst

Rotations:

Constantinos Koumenis
Jan Melenhorst
Junwei Shi

Dongwook (Chris) Choe

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2017

Project Title: Assaying the potential cardioprotective effect of MTSS1 downregulation against dilated cardiomyopathy

Advisor(s):

Kiran Musunuru

Rotations:

Frederic Bushman
Stefano Rivella
Kiran Musunuru

Sangya Agarwal

Gene Therapy and Vaccines
Degree: PhD
Matriculation Year: 2016

Project Title: Investigating the role of cell-intrinsic checkpoint regulators PD1 and CTLA4 in Chimeric antigen receptor T cells

Advisor(s):

Carl June

Rotations:

Carolina Lopez
Carl June
Janis Burkhardt

Yixin Zang

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Crossing the Midline Requires Sequential Proteolysis of the Attractive Frazzled Axon Guidance Receptor

Advisor(s):

Greg Bashaw

Rotations:

Greg Bashaw
Jonathan Raper

Rebecca Windmueller

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Advisor(s):

Edward Morrisey

Rotations:

Edward Morrisey
John Wolfe
Jason Burdick

Aaron Weiner

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Project Title: The role of ΔNp63 in maladaptive regeneration and repair following severe pulmonary injury

Advisor(s):

Andrew Vaughan

Rotations:

Rajan Jain
Andrew Vaughan
Ling Qin

Benjamin Tajer

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2012

Advisor(s):

Mary Mullins

Rotations:

Mary Mullins
Peter Klein
Jonathan Raper

Kelly Sullivan

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Greg Bashaw

Rotations:

Wenqin Luo
Mary Mullins
Greg Bashaw

Kamen Simeonov

Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2014

Project Title: Single cell CRISPR lineage tracing of cancer metastasis

Advisor(s):

Christopher Lengner

Rotations:

Joe Baur
Gerd Blobel
Christopher Lengner
John Murray

Isabel Sierra

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Investigating the nuclear organization of the inactive X in female lymphocytes

Advisor(s):

Montserrat Anguera

Rotations:

Michael Granato
Montserrat Anguera
Marisa Bartolomei

David Sidibe

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Sandra Maday

Rotations:

Kelvin Luk
Isaac Chen
Sandra Maday

Samantha Russell

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Project Title: The Frazzled receptor is required for oocyte development independently of its ligand Netrin

Advisor(s):

Greg Bashaw

Rotations:

Greg Bashaw
Michael Granato
Douglas Epstein

Joel Rurik

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Jonathan Epstein

Rotations:

Mark Kahn
Jonathan Epstein
Edward Morrisey

Gabriella Rice

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Panteleimon Rompolas

Rotations:

Christopher Lengner
Panteleimon Rompolas
Diana Stanescu

Ernest Monahan Vargas

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Yuanquan Song

Rotations:

Greg Bashaw
Michael Granato
Yuanquan Song
Judith Grinspan

Derek Liberti

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2016

Project Title: Alveolar plasticity drives lung repair and regeneration via Klf5

Advisor(s):

Edward Morrisey

Rotations:

Paul Gadue
Edward Morrisey
Panteleimon Rompolas

Hannah Kolev

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Project Title: Determining the role of UTX and JMJD3, two H3K27me3 demethylases, in the intestinal epithelium during homeostasis and regeneration

Advisor(s):

Klaus Kaestner

Rotations:

Greg Bashaw
Christopher Lengner
Klaus Kaestner

Siddharth Kishore

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: The role of GATA6 in human pancreas development and pancreas agenesis

Advisor(s):

Paul Gadue

Rotations:

Stewart Anderson
Paul Gadue
Donguen Huh

William Jones

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Mary Mullins

Rotations:

Mary Mullins
Peter Klein
Marisa Bartolomei

Nicholas Holdreith

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Inhibition of LNK (SH2B3) enhances function and engraftment of human hematopoietic stem and progenitor cells

Advisor(s):

Wei Tong

Rotations:

Peter Klein
Montserrat Anguera
Roberto Bonasio
Wei Tong

Maya Hale

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Greg Bashaw

Rotations:

Mary Mullins
Zhaolan Zhou
Greg Bashaw

Melody Esmaeili Ghahfarokhi

Developmental, Stem Cell and Regenerative Biology
Degree: MD/PhD
Matriculation Year: 2011

Advisor(s):

Peter Klein

Rotations:

Mark Kahn
Igor Brodsky
Mitch Weiss
Peter Klein

Zeenat Diwan

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Project Title: Unravelling the Molecular Mechanisms Regulating Blood Vessel Diameters

Advisor(s):

Arndt Siekmann

Alexander Dimitri

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Joseph Fraietta

Rotations:

Paul Gadue
Daniel Rader
Joseph Fraietta

Ryan Daniels

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Robert Mauck

Rotations:

Ling Qin
Robert Mauck
Jason Burdick

Ryan Cheng

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2013

Advisor(s):

Jonathan Raper

Rotations:

Jonathan Raper
Michael Pack
Ben Stanger

My lab uses the developing olfactory system of larval zebrafish as a model to study the formation of neural circuitry. My thesis project is to…Read More

Jessica Brandt

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Jonathan Raper

Rotations:

Sandra Maday
Arndt Siekmann
Michael Granato

Sara Borst

Developmental, Stem Cell and Regenerative Biology
Degree: PhD
Matriculation Year: 2014

Project Title: Investigating the mechanism of familial thrombocytopenia resulting from mono-allelic mutations in ETV6 or RUNX1 using the human pluripotent stem cell model

Advisor(s):

Paul Gadue

Rotations:

Christopher Lengner
Paul Gadue
Anil Rustgi
Michael Pack

Kevin Zhang

Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2016

Project Title: The Impact of Iron on Endolysosomal Function in the Retinal Pigment Epithelium

Advisor(s):

Joshua Dunaief

Rotations:

Lewis Chodosh
Joshua Dunaief
Vera Krymskaya

Anna Garcia Whitlock

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Paul Titchenell

Rotations:

Paul Titchenell
Mitchell Lazar

Katelyn Sweeney

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016

Project Title: Mechanistic dissection of novel regulators of TDP-43 aggregation identified in a genome-wide CRISPR-Cas9 knockout screen

Advisor(s):

Ophir Shalem

Rotations:

Michael Marks
Ophir Shalem
Naiara Aquizu Lopez

Derek Sung

Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2017

Advisor(s):

Mark Kahn

Rotations:

Mark Kahn
Edward Morrisey

Folasade Sofela

Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2016

Project Title: The Role of Metabolism in NF1

Advisor(s):

Amita Sehgal

Rotations:

Thomas Jongens
Amita Sehgal
Douglas Wallace

Alexander Salomon

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016

Advisor(s):

Benjamin Prosser

Rotations:

Robert Heuckeroth
Benjamin Prosser
Christopher Brown

Aileen Ren

Cell Biology, Physiology and Metabolism
Degree: MD/PhD
Matriculation Year: 2015

Advisor(s):

Mark Kahn

Rotations:

Mark Kahn
Robert Heuckeroth
Jorge Henao-Mejia

Yuwei Qi

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Project Title: Explore the mechanisms underlying irradiation-induced immunomodulation in cancer therapy

Advisor(s):

Andy Minn

Rotations:

Foteini Mourkioti
Andy Minn
Eric Witze

Danielle Minichino

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016

Project Title: The effects of hyper MAPK/ERK signaling on dendritic cell immune functions

Advisor(s):

Edward Behrens

Rotations:

Joshua Dunaief
Mitchell Lazar
Edward Behrens

Brittany MacTaggart

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2017

Advisor(s):

Anna Kashina

Rotations:

Anna Kashina
Erika Holzbaur
Erfei Bi

Sean Louzon

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Erica Korb

Rotations:

Jennifer Phillips-Cremins
Erica Korb
James Shorter

Vineet Kulkarni

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Sandra Maday

Rotations:

Mitchell Lazar
Claudio Giraudo
Wei Guo

Ayon Ibrahim

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2014

Advisor(s):

Zoltan Arany

Rotations:

Mitchell Lazar
Zoltan Arany
Patrick Seale

I am studying how the endothelial cells comprising blood vessels regulate fatty acid uptake and transport, as lipid accumulation in organs such as skeletal muscle…Read More

Corey Holman

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2018

Advisor(s):

Patrick Seale

Rotations:

Zoltan Arany
Mitchell Lazar
Patrick Seale

Julie Heffler

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2015

Advisor(s):

Benjamin Prosser

Rotations:

Michael Granato
Greg Bashaw
Benjamin Prosser

Cardiac myocytes are unique in their constant and cyclic exposure to mechanical forces as the heart beats. It has been well-known for decades that changes…Read More

Olivia Harding

Cell Biology, Physiology and Metabolism
Degree: PhD
Matriculation Year: 2016

Project Title: How do the molecular pathways of mitophagy intersect with those of inflammation in neurons; and are these pathways, and their disruption, implicated in the etiology of ALS and other neurodegenerative diseases?

Advisor(s):