Gene Therapy and Vaccines Faculty
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Gene Therapy and Vaccines
Click the faculty member's name to see more detailed information.
Faculty
Faculty areas of research in GTV can be broken up into the following categories:
- Autoimmunity
- Cancer
- Cardiovascular Disease
- Ex vivo Gene Therapy
- Gene Editing
- Gene Therapy
- Immune Therapy
- Neurodegenerative Disease
- Vaccine Development
Faculty name | Brief Research Description |
---|---|
Youhai Chen | The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases. |
Henry Daniell | Autoimmunity, Drug Delivery |
Laura Su | We are interested in how previous antigen experiences impact T cell resposnes to vaccines, infections, and the risk for autoimmunity |
Faculty name | Brief Research Description |
---|---|
Steven Albelda | Solid Tumors |
Gregory Beatty | Solid Tumors |
Frederic Bushman | Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer |
Youhai Chen | The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases. |
Nicola Mason | Solid Tumors |
Faculty name | Brief Research Description |
---|---|
Kiran Musunuru | Atherosclerosis, Cardiovascular Disease, Gene Editing, Lipid Metabolism |
Daniel Rader | Atherosclerosis, Cardiovascular Disease, Lipid Metabolism, Human Genetics, Functional Genomics |
Faculty name | Brief Research Description |
---|---|
Frederic Bushman | Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer |
Peter Kurre | Bone Marrow Failure, Congenital dyserythropoietic anemia, Congenital Sideroblastic Anemia, DBA, Extracellular Vesicle Biology, Fanconi Anemia, HSCs, Lentiviral Vectors |
Stefano Rivella | The focus of the Rivella lab is to gene transfer and genome editing, using hematopoietic stem cells (HSC) as a target. We are also developing new approaches to target HSC in vivo. |
Faculty name | Brief Research Description |
---|---|
Frederic Bushman | Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer |
Beverly Davidson | AAV Vectors, Gene Editing, Neurodegenerative Disease |
Kiran Musunuru | Atherosclerosis, Cardiovascular Disease, Gene Editing, Lipid Metabolism |
Faculty name | Brief Research Description |
---|---|
Valder Arruda | AAV Vectors, Coagulation, Hemophilia |
Jean Bennett | Eye Disease, Neurodegenerative Disease |
Frederic Bushman | Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer |
Youhai Chen | The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases. |
Beverly Davidson | AAV Vectors, Gene Editing, Neurodegenerative Disease |
Hildegund Ertl | Our vaccine efforts focus on the development of viral vector based vaccines to cancer and chronic and emerging viral infections. Our gene therapy efforts focus on pathways to prevent immune-mediated rejection of AAV vectors targeted to liver |
Daniel Rader | Atherosclerosis, Cardiovascular Disease, Lipid Metabolism, Human Genetics, Functional Genomics |
Stefano Rivella | The focus of the Rivella lab is to gene transfer and genome editing, using hematopoietic stem cells (HSC) as a target. We are also developing new approaches to target HSC in vivo. |
Denise Sabatino | The lab focuses on development of novel factor VIII proteins with enhanced function, AAV-mediated gene therapy for hemophilia and understanding the biological consequences of AAV delivery of factor VIII. |
Dwight Stambolian | Eye Disease |
Hansell Stedman | AAV Vectors, Muscular Dystrophy, Gene Therapy |
James Wilson | AAV Vectors, Adenoviruses, Gene editing, COVID19 |
John Wolfe | Neurodegenerative Disease, AAV vectors, neural stem cells, retinal progenitor cells |
Faculty name | Brief Research Description |
---|---|
Frederic Bushman | Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer |
Bruce Freedman | Immune Therapies |
Saar Gill | Adoptive Cellular Therapy, CART, HSCs, Immune Therapy, Liquid Tumors |
Stephen Grupp | Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors |
Carl June | Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors |
Daniel Kulp | DNA vaccine, immune therapy, protein engineering |
Bruce Levine | Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors |
Gerald Linette | Human Cancer Immunology is the focus of our laboratory. We isolate TCRs specific for neoantigen p-MHC expressed in solid tumors. Emphasis is placed on translation to the clinic. |
Michela Locci | Complex biology of Tfh cells using a multidisciplinary approach that combines cellular and molecular immunology as well as transcriptomics. T follicular helper and antibody responses following immunization with SARS-CoV-2 mRNA vaccines |
Nicola Mason | Solid Tumors |
J. Joseph Melenhorst | Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors |
Michael Milone | Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors |
Edmund Moon | Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors |
Avery Posey | We are fascinated with the study of sugars (glycans) within cancer immunology. We identify novel differentially glycosylated peptides on tumor cells and design chimeric antigen receptors to target these antigens. Additionally, we alter the glycome of immune cells and study their roles in effector immune functions. |
Daniel Powell | Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors |
Marco Ruella | The lab focuses on development of novel factor VIII proteins with enhanced function, AAV-mediated gene therapy for hemophilia and understanding the biological consequences of AAV delivery of factor VIII. |
Faculty name | Brief Research Description |
---|---|
Frederick (Chris) Bennett | Neurodegenerative diseases, Microglia |
Beverly Davidson | AAV Vectors, Gene Editing, Neurodegenerative Disease |
Stephen Douglas | Neurodegenerative Disease |
Ronald Rubenstein | Cystic Fibrosis, Muscular Dystrophy |
John Wolfe | Neurodegenerative Disease, AAV vectors, neural stem cells, retinal progenitor cells |
Faculty name | Brief Research Description |
---|---|
Beatriz Carreno | Solid Tumors, Vaccine |
Hildegund Ertl | Our vaccine efforts focus on the development of viral vector based vaccines to cancer and chronic and emerging viral infections. Our gene therapy efforts focus on pathways to prevent immune-mediated rejection of AAV vectors targeted to liver |
Luis Montaner | HIV, Vaccine, COVID19 |
Paul Offit |
Vaccine |
Norbert Pardi | RNA Delivery, Vaccine |
Laura Su | We are interested in how previous antigen experiences impact T cell resposnes to vaccines, infections, and the risk for autoimmunity |
David Weiner | DNA Vaccine, Vaccine, genetic delivery, Monclonal antibody engineering, invivo antigen assembly |
For information on how to apply for CAMB Faculty membership, please see the CAMB Bylaws.