Gene Therapy and Vaccines Faculty

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Gene Therapy and Vaccines Members

Current Members

Gene Therapy and Vaccines

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Faculty


Faculty areas of research in GTV can be broken up into the following categories:
GTV Faculty Brief Research Description
Youhai Chen The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases.
Henry Daniell Autoimmunity, Drug Delivery
Laura Su We are interested in how previous antigen experiences impact T cell resposnes to vaccines, infections, and the risk for autoimmunity

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GTV Faculty Brief Research Description
Steven Albelda Solid Tumors
Gregory Beatty Solid Tumors
Youhai Chen The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases.
Nicola Mason Solid Tumors

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GTV Faculty Brief Research Description
Kiran Musunuru Atherosclerosis, Cardiovascular Disease, Gene Editing, Lipid Metabolism
Daniel Rader Atherosclerosis, Cardiovascular Disease, Lipid Metabolism, Human Genetics, Functional Genomics

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GTV Faculty Brief Research Description
Peter Kurre Bone Marrow Failure, Congenital dyserythropoietic anemia, Congenital Sideroblastic Anemia, DBA, Extracellular Vesicle Biology, Fanconi Anemia, HSCs, Lentiviral Vectors
Stefano Rivella The focus of the Rivella lab is to gene transfer and genome editing, using hematopoietic stem cells (HSC) as a target. We are also developing new approaches to target HSC in vivo.

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GTV Faculty Brief Research Description
Beverly Davidson AAV Vectors, Gene Editing, Neurodegenerative Disease
Kiran Musunuru Atherosclerosis, Cardiovascular Disease, Gene Editing, Lipid Metabolism

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GTV Faculty Brief Research Description
Valder Arruda AAV Vectors, Coagulation, Hemophilia
Jean Bennett Eye Disease, Neurodegenerative Disease
Youhai Chen The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases.
Beverly Davidson AAV Vectors, Gene Editing, Neurodegenerative Disease
Hildegund Ertl Our vaccine efforts focus on the development of viral vector based vaccines to cancer and chronic and emerging viral infections. Our gene therapy efforts focus on pathways to prevent immune-mediated rejection of AAV vectors targeted to liver
Daniel Rader Atherosclerosis, Cardiovascular Disease, Lipid Metabolism, Human Genetics, Functional Genomics
Stefano Rivella The focus of the Rivella lab is to gene transfer and genome editing, using hematopoietic stem cells (HSC) as a target. We are also developing new approaches to target HSC in vivo.
Denise Sabatino The lab focuses on development of novel factor VIII proteins with enhanced function, AAV-mediated gene therapy for hemophilia and understanding the biological consequences of AAV delivery of factor VIII.
Dwight Stambolian Eye Disease
Hansell Stedman AAV Vectors, Muscular Dystrophy, Gene Therapy
James Wilson AAV Vectors, Adenoviruses, Gene editing, COVID19
John Wolfe Neurodegenerative Disease, AAV vectors, neural stem cells, retinal progenitor cells

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GTV Faculty Brief Research Description
Bruce Freedman Immune Therapies
Saar Gill Adoptive Cellular Therapy, CART, HSCs, Immune Therapy, Liquid Tumors
Stephen Grupp Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Carl June Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Daniel Kulp DNA vaccine, immune therapy, protein engineering
Bruce Levine Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Gerald Linette Human Cancer Immunology is the focus of our laboratory. We isolate TCRs specific for neoantigen p-MHC expressed in solid tumors. Emphasis is placed on translation to the clinic.
Nicola Mason Solid Tumors
J. Joseph Melenhorst Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Michael Milone Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Edmund Moon Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Avery Posey We are fascinated with the study of sugars (glycans) within cancer immunology. We identify novel differentially glycosylated peptides on tumor cells and design chimeric antigen receptors to target these antigens. Additionally, we alter the glycome of immune cells and study their roles in effector immune functions.
Daniel Powell Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Marco Ruella The lab focuses on development of novel factor VIII proteins with enhanced function, AAV-mediated gene therapy for hemophilia and understanding the biological consequences of AAV delivery of factor VIII.
   

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GTV Faculty Brief Research Description
Frederick (Chris) Bennett Neurodegenerative diseases, Microglia
Beverly Davidson AAV Vectors, Gene Editing, Neurodegenerative Disease
Stephen Douglas Neurodegenerative Disease
Ronald Rubenstein Cystic Fibrosis, Muscular Dystrophy
John Wolfe Neurodegenerative Disease, AAV vectors, neural stem cells, retinal progenitor cells

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GTV Faculty Brief Research Description
Beatriz Carreno Solid Tumors, Vaccine
Hildegund Ertl Our vaccine efforts focus on the development of viral vector based vaccines to cancer and chronic and emerging viral infections. Our gene therapy efforts focus on pathways to prevent immune-mediated rejection of AAV vectors targeted to liver
Luis Montaner HIV, Vaccine, COVID19
Paul Offit

Vaccine

Norbert Pardi RNA Delivery, Vaccine
Laura Su We are interested in how previous antigen experiences impact T cell resposnes to vaccines, infections, and the risk for autoimmunity
David Weiner DNA Vaccine, Vaccine, genetic delivery, Monclonal antibody engineering, invivo antigen assembly

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For information on how to apply for CAMB Faculty membership, please see the CAMB Bylaws.