Gene Therapy and Vaccines Faculty

Gene Therapy and Vaccines Members

Current Members

Gene Therapy and Vaccines

Click the faculty member's name to see more detailed information.

Faculty

Steven M. Albelda, MD	Jan Joseph Melenhorst, PhD
Valder R. Arruda, MD, PhD	Michael C. Milone, M.D., Ph.D.
Gregory L. Beatty, MD, PhD	Luis J. Montaner, DVM, DPhil
Jean Bennett, MD, PhD	Edmund K Moon, MD
Frederick Christian Bennett, M.D.	Kiran Musunuru, MD, PhD, MPH, ML
Beatriz M. Carreno, PhD	Paul A. Offit
Youhai H. Chen, M.B., Ph.D.	Norbert Pardi, PhD
Henry Daniell, Ph.D.	Avery D Posey, PhD
Beverly L. Davidson, Ph.D.	Daniel J. Powell Jr., Ph.D.
Steven D. Douglas, M.D.	Daniel J Rader, MD
Hildegund C.J. Ertl, MD	Ronald C. Rubenstein, MD, PhD
Bruce D. Freedman V.M.D., Ph.D	Marco Ruella, MD
Lindsey A. George, M.D.	Denise E. Sabatino, Ph.D.
Saar I Gill, MD, PhD	Dwight E. Stambolian, MD, PhD
Stephan A. Grupp, MD, PhD	Hansell H. Stedman, MD
Carl H. June, M.D.	Laura F Su, M.D. Ph.D.
Peter Kurre, MD	David B. Weiner, Ph.D.
Bruce L. Levine, Ph.D.	James M. Wilson, MD, PhD
Gerald P Linette, MD, PhD	John H. Wolfe VMD, PhD
Nicola J Mason, B.Vet.Med DACVIM PhD

Faculty areas of research in GTV can be broken up into the following categories:

Faculty name	Brief Research Description
Youhai Chen	The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases.
Henry Daniell	Autoimmunity, Drug Delivery
Laura Su	We are interested in how previous antigen experiences impact T cell resposnes to vaccines, infections, and the risk for autoimmunity

Faculty name	Brief Research Description
Steven Albelda	Solid Tumors
Gregory Beatty	Solid Tumors
Frederic Bushman	Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer
Youhai Chen	The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases.
Nicola Mason	Solid Tumors

Faculty name	Brief Research Description
Kiran Musunuru	Atherosclerosis, Cardiovascular Disease, Gene Editing, Lipid Metabolism
Daniel Rader	Atherosclerosis, Cardiovascular Disease, Lipid Metabolism, Human Genetics, Functional Genomics

Faculty name	Brief Research Description
Frederic Bushman	Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer
Peter Kurre	Bone Marrow Failure, Congenital dyserythropoietic anemia, Congenital Sideroblastic Anemia, DBA, Extracellular Vesicle Biology, Fanconi Anemia, HSCs, Lentiviral Vectors
Stefano Rivella	The focus of the Rivella lab is to gene transfer and genome editing, using hematopoietic stem cells (HSC) as a target. We are also developing new approaches to target HSC in vivo.

Faculty name	Brief Research Description
Frederic Bushman	Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer
Beverly Davidson	AAV Vectors, Gene Editing, Neurodegenerative Disease
Kiran Musunuru	Atherosclerosis, Cardiovascular Disease, Gene Editing, Lipid Metabolism

Faculty name	Brief Research Description
Valder Arruda	AAV Vectors, Coagulation, Hemophilia
Jean Bennett	Eye Disease, Neurodegenerative Disease
Frederic Bushman	Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer
Youhai Chen	The lab is developing gene therapy approaches for the treatment of cancer and autoimmune diseases.
Beverly Davidson	AAV Vectors, Gene Editing, Neurodegenerative Disease
Hildegund Ertl	Our vaccine efforts focus on the development of viral vector based vaccines to cancer and chronic and emerging viral infections. Our gene therapy efforts focus on pathways to prevent immune-mediated rejection of AAV vectors targeted to liver
Daniel Rader	Atherosclerosis, Cardiovascular Disease, Lipid Metabolism, Human Genetics, Functional Genomics
Stefano Rivella	The focus of the Rivella lab is to gene transfer and genome editing, using hematopoietic stem cells (HSC) as a target. We are also developing new approaches to target HSC in vivo.
Denise Sabatino	The lab focuses on development of novel factor VIII proteins with enhanced function, AAV-mediated gene therapy for hemophilia and understanding the biological consequences of AAV delivery of factor VIII.
Dwight Stambolian	Eye Disease
Hansell Stedman	AAV Vectors, Muscular Dystrophy, Gene Therapy
James Wilson	AAV Vectors, Adenoviruses, Gene editing, COVID19
John Wolfe	Neurodegenerative Disease, AAV vectors, neural stem cells, retinal progenitor cells

Faculty name	Brief Research Description
Frederic Bushman	Human microbiome, human gene therapy HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer
Bruce Freedman	Immune Therapies
Saar Gill	Adoptive Cellular Therapy, CART, HSCs, Immune Therapy, Liquid Tumors
Stephen Grupp	Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Carl June	Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Daniel Kulp	DNA vaccine, immune therapy, protein engineering
Bruce Levine	Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Gerald Linette	Human Cancer Immunology is the focus of our laboratory. We isolate TCRs specific for neoantigen p-MHC expressed in solid tumors. Emphasis is placed on translation to the clinic.
Michela Locci	Complex biology of Tfh cells using a multidisciplinary approach that combines cellular and molecular immunology as well as transcriptomics. T follicular helper and antibody responses following immunization with SARS-CoV-2 mRNA vaccines
Nicola Mason	Solid Tumors
J. Joseph Melenhorst	Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Michael Milone	Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Edmund Moon	Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Avery Posey	We are fascinated with the study of sugars (glycans) within cancer immunology. We identify novel differentially glycosylated peptides on tumor cells and design chimeric antigen receptors to target these antigens. Additionally, we alter the glycome of immune cells and study their roles in effector immune functions.
Daniel Powell	Adoptive Cellular Therapy, CART, Immune Therapy, Liquid Tumors
Marco Ruella	The lab focuses on development of novel factor VIII proteins with enhanced function, AAV-mediated gene therapy for hemophilia and understanding the biological consequences of AAV delivery of factor VIII.

Faculty name	Brief Research Description
Frederick (Chris) Bennett	Neurodegenerative diseases, Microglia
Beverly Davidson	AAV Vectors, Gene Editing, Neurodegenerative Disease
Stephen Douglas	Neurodegenerative Disease
Ronald Rubenstein	Cystic Fibrosis, Muscular Dystrophy
John Wolfe	Neurodegenerative Disease, AAV vectors, neural stem cells, retinal progenitor cells

Faculty name	Brief Research Description
Beatriz Carreno	Solid Tumors, Vaccine
Hildegund Ertl	Our vaccine efforts focus on the development of viral vector based vaccines to cancer and chronic and emerging viral infections. Our gene therapy efforts focus on pathways to prevent immune-mediated rejection of AAV vectors targeted to liver
Luis Montaner	HIV, Vaccine, COVID19
Paul Offit	Vaccine
Norbert Pardi	RNA Delivery, Vaccine
Laura Su	We are interested in how previous antigen experiences impact T cell resposnes to vaccines, infections, and the risk for autoimmunity
David Weiner	DNA Vaccine, Vaccine, genetic delivery, Monclonal antibody engineering, invivo antigen assembly

For information on how to apply for CAMB Faculty membership, please see the CAMB Bylaws.