Genetics and Epigenetics Faculty

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Current Members

Genetics and Epigenetics

Click the faculty member's name to see more detailed information.

Faculty

Rebecca Ahrens-Nicklas, MD, PhD	Matthew S Kayser, MD, PhD
Naiara Aquizu Lopez, Ph.D.	Brendan James Keating, Ph.D.
Michael L. Atchison, PhD	Rachel L. Kember, M.Sc., Ph.D.
Yoseph Barash, Ph.D.	Eugene Khandros, MD, PhD
Marisa S. Bartolomei, Ph.D.	Erica Korb, PhD
Craig H. Bassing, Ph.D.	Mitchell A. Lazar, MD, PhD
Shelley L. Berger, Ph.D.	Frank S. Lee, MD, PhD
Elizabeth Bhoj, M.D., Ph.D.	Mia Tauna Levine, PhD
Ben E. Black, Ph.D.	Lan Lin, Ph.D.
Kahlilia Blanco	Eline Tjetske Luning Prak, MD, PhD
M. Andres Blanco, PhD	Kristen W. Lynch, PhD
Gerd A. Blobel, MD, PhD	Ronen Marmorstein, Ph.D.
Roberto Bonasio, Ph.D.	Iain Mathieson, Ph.D.
Nancy M. Bonini, Ph.D.	Zissimos Mourelatos, M.D.
Edward Stuart Brodkin, M.D.	John Isaac Murray, Ph.D.
Christopher D Brown, Ph.D.	Aimee S. Payne, MD,PhD
Maja Bucan, Ph.D.	Liming Pei, Ph.D.
Brian C Capell, M.D., Ph.D.	Richard Edmund Phillips, MD PhD
Alice S. Chen-Plotkin, MD	Jennifer E. Phillips-Cremins, Ph.D.
Alessandra Chesi, PhD	David M. Raizen, MD, PhD
Shinjae Chung, Ph.D.	Arjun Raj, PhD
Colin Conine, PhD	Marylyn D Ritchie, PhD
Ana G Cristancho, MD, PhD	Melanie Ruffner, MD, PhD
Pablo G Cámara, PhD	J. Eric Russell, M.D.
Sharlene M. Day, MD	Ophir Shalem, Ph.D.
Yanxiang Deng, PhD	Eileen M. Shore, Ph.D.
Gideon Dreyfuss, Ph.D.	Rebecca A. Simmons
Andrew C. Edmondson, MD, PhD	Nancy B. Spinner, Ph.D.
Douglas J. Epstein, Ph.D.	Doris A. Stoffers, M.D., Ph.D
Robert Babak Faryabi, Ph.D.	Katalin Susztak, MD, PhD
Michael J. Gandal, MD, Ph.D.	Sarah A. Tishkoff, Ph.D.
Ziyue Gao, PhD	Golnaz Vahedi, Ph.D.
Louis Ghanem, MD, PhD	Benjamin Franklin Voight, Ph.D.
Struan F.A. Grant, PhD	Doris Wagner, PhD
Roger A. Greenberg, MD, PhD	Li-San Wang, Ph.D.
Brian Gregory	Kai Wang, Ph.D.
Hakon Hakonarson, MD, PhD	Franz Weber, Ph.D.
Michael P Hart, PhD	Andrew D. Wells, Ph.D.
Elizabeth A Heller, PhD	Hao Wu, Ph.D.
Thomas A. Jongens, Ph.D.	Yi Xing, Ph.D.
Eric F. Joyce, Ph.D.	Kenneth S. Zaret, PhD
Klaus H. Kaestner, Ph.D.	Wanding Zhou, Ph.D.
Jennifer M. Kalish, MD, PhD	Lijun Zhou, PhD
Jonathan P. Katz, MD	Zhaolan (Joe) Zhou, Ph.D.

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Faculty areas of research in G&E can be broken up into the following categories:

• Human Genetics
• Genetics of Model Organisms - C elegans
• Genetics of Model Organisms - Drosophila
• Genetics of Model Organisms - Mouse
• Genetics of Model Organisms - Plants
• Genetics of Model Organisms - S. cerevisiae
• Genetics of Microbes and Viruses
• Developmental Genetics
• Behavioral Genetics and Neurobiology
• Cancer Genetics and Signal Transduction
• Genetics of Diabetes and Metabolism
• Animal Modeling of Human Disease 
• Transcriptional Gene Regulation
• Post-Transcriptional Gene Regulation
• Epigenetics and Chromatin
• Bioinformatics and Genomics

Human Genetics

G&E Faculty	Brief Research Description
Naiara Aquizu Lopez	Our research interest is to better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders.
Ben Black	Chromosome inheritance in somatic cells and through the germline, epigenetic and genetic contributions at mammalian centromeres, chromatin structural biochemistry and biophysics, chromatin complexes that signal errors in cell division and DNA damage during the rest of the cell cycle, chromatin assembly, mass spec-based proteomics and biophysical studies of chromosome complexes
Christopher Brown	Our research focuses on how genotypes produce phenotypes and how they vary and evolve
Maja Bucan	Genetic dissection of complex behaviors in mice; Functional genomics
Alice Chen-Plotkin	I am interested in neurodegenerative diseases; my research approach uses genomic-scale screens to identify leads for downstream mechanistic follow-up in cell culture systems.
Gideon Dreyfuss	RNA-binding proteins, nuclear transport of proteins and mRNAs, RNA processing, neurodegenerative disease, high throughput approaches to drug discovery.
Struan Grant	Utilizing high-throughput genotyping and sequencing technologies, combined with statistical and bioinformatic approaches, my goals include unraveling genomic puzzles related to childhood obesity, pediatric bone strength determination, early onset diabetes and cancer.
Casey Greene	Our overarching goal is to transform how we understand complex biological systems by developing and applying computational algorithms that effectively model processes by integrating multiple types of big data from diverse experiments.
Hakon Hakonarson	Genetics of common and rare human diseases, using high-throughput sequencing and genotyping approaches
Jennifer Kalish	Understanding and improving detection of epigenetics and mosaicism in human disease
Nina Luning Prak	mobile DNA, rearrangement of immunoglobulin genes, regulation of L1 retrotransposition
Jason Moore	Assessing polygenic risk of disease using electronic health record data
Aimee Payne	Genetic and functional characterization of human autoantibody repertoires; Targeted therapy for pemphigus ; Regulation of desmosome assembly and disassembly
J. Eric Russell	Control and function of human embryonic globin genes.
Eileen M. Shore	Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes.
Nancy Spinner	Human Genetics, Notch signaling in human disease, Alagille syndrome, human disease gene identifcation by mapping deletions.
Kai Tan	Model gene regulatory networks in development and disease
Sarah Tishkoff	Human Genetics, complex disease, human evolution, infectious disease, malaria, evolutionary biology, natural selection, adaptation.
Golnaz Vahedi	Epigenetics, Immunology, Human Genetics, Bioinformatics, Computational Biology, Machine-learning
Benjamin Voight	Using statistical genetics, population genetics, and computational biology toward understanding the biological underpinnings and evolutionary history of human phenotypes

Other CAMB Faculty	Brief Research Description
Daniel Rader	Genetic regulation of lipid and lipoprotein metabolism and molecular relationship to atherosclerosis.
Dwight Stambolian	Gene discovery of complex and monogenic disorders.

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Genetics of Model Organisms - C elegans

G&E Faculty	Brief Research Description
Nancy Bonini	Molecular genetics of neurodegenerative disease.
Brian Gregory	RNA silencing, RNA degradation, RNA stability, microRNAs, small RNAs
John Murray	Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging
David Raizen	The regulation and purpose of sleep-like behavior in C. elegans.
Arjun Raj	RNA systems biology, particular as related to non-coding RNAs and cancer biology.
Meera Sundaram	Regulation and targets of Ras/ERK signaling in C. elegans

Other CAMB Faculty	Brief Research Description
Meera Sundaram	Regulation and targets of Ras/ERK signaling in C. elegans

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Genetics of Model Organisms - Drosophila

G&E Faculty	Brief Research Description
Michael Atchison	Control of Gene Expression, development, and oncogenesis.
Thomas Jongens	Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification
Eric Joyce	Form and function of nuclear compartments and chromosome positioning
Shawn Little	Transcription dynamics; Cell fate specification; RNA production, processing, transport, localization
Amita Sehgal	Molecular basis of behavior

Other CAMB Faculty	Brief Research Description
Greg Bashaw	Signaling mechanisms that function during attractive and repulsive axon guidance.
Sara Cherry	Genetic and mechanistic studies of viral-host interactions.
Steve Dinardo	Stem cell function; developmental patterning.
Greg Guild	Shaping Drosophila cells with the actin cytoskeleton.

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Genetics of Model Organisms - Mouse

G&E Faculty	Brief Research Description
Michael Atchison	Control of Gene Expression, development, and oncogenesis.
Marisa Bartolomei	Genomic imprinting and X inactivation in mice.
Craig Bassing	My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies
Ben Black	Chromosome inheritance in somatic cells and through the germline, epigenetic and genetic contributions at mammalian centromeres, chromatin structural biochemistry and biophysics, chromatin complexes that signal errors in cell division and DNA damage during the rest of the cell cycle, chromatin assembly, mass spec-based proteomics and biophysical studies of chromosome complexes
Edward S. Brodkin	Genetic analysis of social behaviors (aggressive and affiliative behaviors) and related brain phenotypes in mouse models relevant to autism and schizophrenia.
Douglas Epstein	Regulation of Sonic hedgehog signaling in development and disease
David L. Gasser	Genes that affect the immune response
Eric Joyce	Form and function of nuclear compartments and chromosome positioning
Yana Kamberov	Evolution of human specific traits; Genetics of skin appendage development and evolution; Mouse models to understand the functional significance of adaptive genetic changes;identification and functional testing of regulatory elements driving human evolution
Brett Kaufman	The role of mitochondrial chromatin organization in gene expression, resistance to damage, and genome transmission.
Frank Lee	Molecular mechanisms of the hypoxic response.
Nina Luning Prak	mobile DNA, rearrangement of immunoglobulin genes, regulation of L1 retrotransposition
Kazuko Nishikura	RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation.
Aimee Payne	*Genetic and functional characterization of human autoantibody repertoires *Targeted therapy for pemphigus *Regulation of desmosome assembly and disassembly
John R. Pehrson	Role of histone variants in regulating chromatin structure and function
J. Eric Russell	Control and function of human embryonic globin genes.
Doris Stoffers	Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Katalin Susztak	Work in my laboratory is aimed toward the understanding of molecular pathways that govern chronic kidney disease development
Kenneth Zaret	Mammalian gene regulation, cell differentiation, chromatin structure.
Zhaolan (Joe) Zhou	Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease

Other CAMB Faculty	Brief Research Description
Lewis Chodosh	Genetically engineered mouse models for breast cancer; Cancer stem cells; Molecular therapeutics; Genomics; Non-invasive imaging.
E. Bryan Crenshaw	Analysis of the role of developmental regulatory factors during mouse embryogenesis.
Jonathan Epstein	Transcriptional regulation of cardiac development and function using mouse models.
Xianxin Hua	The critical role of the tumor suppressor Menin in regulation of cell proliferation, apoptosis, and genome stability. Signal transduction mediated by transforming growth factor beta (TGF-b).
Olena Jacenko	Molecular mechanisms of skeletal development and blood cell differentiation.
Brad Johnson	Molecular biology of aging, Werner syndrome, telomeres, recombination.
Anna Kashina	Protein modifications, mouse genetics, cancer, cytoskeleton, cardiovascular development, angiogenesis.
Klaus Kaestner	Dr. Kaestner’s lab is employing modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract.
Sarah Millar	Intercellular signals regulating the development of hair follicles, teeth and mammary glands and postnatal hair growth.
Ed Morrisey	Lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors.
Michael Parmacek	Transcriptional programs that regulate cardiovascular development.
Daniel Rader	Genetic regulation of lipid and lipoprotein metabolism and molecular relationship to atherosclerosis.
Anil Rustgi	Oncogenes, tumor suppressor genes, molecular genetics of GI cancers (colon, pancreatic, upper GI).
Richard Schultz	Egg activation and gene expression in mouse embryos.
Celeste Simon	Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation.
Nancy Speck	Hematopoietic stem cells and leukemia using mouse models
Ben Stanger	Organogenesis, Stem Cells, Pancreatic Cancer, Regulation of Organ Size.

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Genetics of Model Organisms - Plants

G&E Faculty	Brief Research Description
Brian Gregory	RNA silencing, RNA degradation, RNA stability, microRNAs, small RNAs
Doris Wagner	Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.

Other CAMB Faculty	Brief Research Description
Scott Poethig	Regulation of developmental timing and organ polarity in plants.

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Genetics of Model Organisms - S. cerevisiae

G&E Faculty	Brief Research Description
Shelley Berger	Chromatin structure and function in gene regulation; post-translational modifications of transcription factors and histones; genetic, biochemical and structural analysis of chromatin in S. cerevisiae and human cells; role of interrelated factor/histone modifications in cancer and viral infection.

Other CAMB Faculty	Brief Research Description
Erfei Bi	Development of cell polarity and control of cytokinesis in budding yeast.
Andrew Dancis	Iron transport into mitochondria, Heme sythesis, Fe-S cluster biogenesis, Yeast genetics, and Sideroblastic anemia
Wei Guo	The molecular basis for polarized exocytosis and how exocytosis contributes to polarized cell growth and morphogenesis.
Brad Johnson	Molecular biology of aging, Werner syndrome, telomeres, recombination.
Frank Luca	Yeast and mammalian cell cycle regulation; Cytokinesis. Daughter cell-specific gene expression; Polarized growth Mitotic Exit Network (MEN); Regulation of Ace2-dependent transcription and Morphogenesis (RAM).

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Genetics of Microbes and Viruses

Other CAMB Faculty	Brief Research Description
Frederic Bushman	Virology, HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer.
Sara Cherry	Genetic and mechanistic studies of viral-host interactions.
Mark Goulian	Bacterial regulatory circuits and signal transduction
Elizabeth Grice	Genomic approaches to understand host-microbe interactions at the cutaneous surface in health and disease.
Paul Lieberman	Genome maintenance and gene expression; Gammaherpesviruses and oncogenesis; Telomere Biology, Chromatin structure and genome stability; Transcription regulation.
Mechthild Pohlschroder	Prokaryotic Protein Translocation across Hydrophobic Membranes and Their Substrates.
David Roos	Molecular parasitology, host-pathogen interactions, drug targets & resistance mechanisms, evolution of eukaryotic cells & organellar function, genome databases & database mining, comparative genomics, computational biology, Toxoplasma gondii, Plasmodium falciparum.
Matthew Weitzman	Virology, Virus Replication, DNA Damage and Repair, Genome Instability, Viral Vectors
Jun Zhu	Quorum Sensing, Bacterial pathogenesis, Biofilms, Vibrio cholerae.

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Developmental Genetics

G&E Faculty	Brief Research Description
Naiara Aquizu Lopez	Our research interest is to better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders.
Michael Atchison	Control of Gene Expression, development, and oncogenesis.
Craig Bassing	My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies
Roberto Bonasio	Epigenetics, chromatin, noncoding RNAs, ants
Gerd Blobel	Hematopoiesis, gene expression, transcription factors, chromatin
Brian Capell	Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system.
Jennifer Cremins	The Cremins lab investigates the link between three-dimensional organization of genomes and the establishment and maintenance of cellular function.
Douglas Epstein	Regulation of Sonic hedgehog signaling in development and disease
Thomas Jongens	Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification
Eric Joyce	Form and function of nuclear compartments and chromosome positioning
Yana Kamberov	Evolution of human specific traits; Genetics of skin appendage development and evolution; Mouse models to understand the functional significance of adaptive genetic changes;identification and functional testing of regulatory elements driving human evolution
Shawn Little	Transcription dynamics; Cell fate specification; RNA production, processing, transport, localization
John Murray	Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging
Kazuko Nishikura	RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation.
Aimee Payne	*Genetic and functional characterization of human autoantibody repertoires *Targeted therapy for pemphigus *Regulation of desmosome assembly and disassembly
Nancy Spinner	Human Genetics, Notch signaling in human disease, Alagille syndrome, human disease gene identifcation by mapping deletions.
Eileen M. Shore	Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes.
Doris Stoffers	Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Katalin Susztak	Work in my laboratory is aimed toward the understanding of molecular pathways that govern chronic kidney disease development.
Kai Tan	Model gene regulatory networks in development and disease
Doris Wagner	Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.
Mitchell Weiss	Developmental Hematopoiesis concentrating on red blood cell and megakaryocyte lineages.
Kenneth Zaret	Mammalian gene regulation, cell differentiation, chromatin structure.
Zhaolan (Joe) Zhou	Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease

Other CAMB Faculty	Brief Research Description
Greg Bashaw	Signaling mechanisms that function during attractive and repulsive axon guidance.
E. Bryan Crenshaw	Analysis of the role of developmental regulatory factors during mouse embryogenesis.
Steve DiNardo	Stem Cell Function; developmental patterning.
Jonathan Epstein	Transcriptional regulation of cardiac development and function using mouse models.
Amin Ghabrial	How cells make and shape tubular organs
Michael Granato	Axonal guidance and motor behavior regulation in the zebrafish.
Greg Guild	Shaping Drosophila cells with the actin cytoskeleton.
Olena Jacenko	Molecular mechanisms of skeletal development and blood cell differentiation.
Brian Keith	How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression.
Sarah Millar	Intercellular signals regulating the development of hair follicles, teeth and mammary glands and postnatal hair growth.
Ed Morrisey	Lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors.
Mary Mullins	BMP signal transduction; molecular mechanisms of cell specification establishment of the vertebrate body plan via maternal control mechanisms.
Michael Pack	Genetic analysis of vertebrate digestive organ development using the zebrafish.
Micahel Parmacek	Transcriptional programs that regulate cardiovascular development.
Scott Poethig	Regulation of developmental timing and organ polarity in plants.
Patrick Seale	Transcriptional control of adipocyte formation and function
Richard Schultz	Egg activation and gene expression in mouse embryos.
Celeste Simon	Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation.
Nancy Speck	Hematopoietic stem cells and leukemia using mouse models
Ben Stanger	Organogenesis, Stem Cells, Pancreatic Cancer, Regulation of Organ Size.
Meera Sundaram	Regulation and targets of Ras/ERK signaling in C. elegans

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Behavioral Genetics and Neurobiology

G&E Faculty	Brief Research Description
Roberto Bonasio	Epigenetics, chromatin, noncoding RNAs, ants
Nancy Bonini	Molecular genetics of neurodegenerative disease.
Edward S. Brodkin	Genetic analysis of social behaviors (aggressive and affiliative behaviors) and related brain phenotypes in mouse models relevant to autism and schizophrenia.
Maja Bucan	Genetic dissection of complex behaviors in mice; Functional genomics
Alice Chen-Plotkin	I am interested in neurodegenerative diseases; my research approach uses genomic-scale screens to identify leads for downstream mechanistic follow-up in cell culture systems.
Douglas Epstein	Regulation of Sonic hedgehog signaling in development and disease
Thomas Jongens	Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification
Erica Korb	Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders
Kazuko Nishikura	RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation.
David Raizen	The regulation and purpose of sleep-like behavior in C. elegans
Amita Sehgal	Molecular basis of behavior
Franz Weber	We employ a multidisciplinary approach to study the regulation and function of REM sleep and seek to mechanistically understand how this brain state influences our emotions and behavior in health and disease.
Zhaolan (Joe) Zhou	Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease

Other CAMB Faculty	Brief Research Description
Greg Bashaw	Signaling mechanisms that function during attractive and repulsive axon guidance.
Michael Granato	Axonal guidance and motor behavior regulation in the zebrafish.

Close

Cancer Genetics and Signal Transduction

G&E Faculty	Brief Research Description
Craig Bassing	My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies
Andres Blanco	I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs.
Gerd Blobel	Hematopoiesis, gene expression, transcription factors, chromatin
Russ Carstens	Study of the molecular mechanisms of alternative splicing.
Brian Capell	Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system.
Douglas Epstein	Regulation of Sonic hedgehog signaling in development and disease
Robert Faryabi	Develop analytical methods for precision cancer genomics.
Donna L. George	Our research interests are focused broadly on the molecular pathways governing cellular growth control and their disruption during the initiation and progression of human cancers.
Jennifer Kalish	Understanding and improvingdetection of epigenetics and mosaicismin human disease
Maureen Murphy	p53 tumor suppressor, HSP70 chaperone, autophagy, programmed cell death. Keywords: Cancer Genetics and Signal Transduction, Genetics of diabetes and metabolism, Animal modeling of human disease
Doris Stoffers	Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Kai Tan	Model gene regulatory networks in development and disease
Doris Wagner	Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.

Other CAMB Faculty	Brief Research Description
Craig Bassing	Elucidation of molecular mechanisms which regulate the initiation and proper repair of DNA double strand breaks during chromosomal V(D)J recombination.
Garrett Brodeur	Molecular biology and genetics of childhood cancer, especially neuroblastoma.
Lewis Chodosh	Genetically engineered mouse models for breast cancer; Cancer stem cells; Molecular therapeutics; Genomics; Non-invasive imaging.
David Feldser	Mechanisms of tumor-suppressor gene action; Role of the immune system in tumor suppression; Genome engineering in the mouse; Chemical genetic strategies to modulate tumor suppression
Brian Keith	How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression.
Warren Pear	Processes that control normal development and malignant transformation.
Anil Rustgi	Oncogenes, tumor suppressor genes, molecular genetics of GI cancers (colon, pancreatic, upper GI).
Celeste Simon	Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation.
Ben Stanger	Organogenesis, Stem Cells, Pancreatic Cancer, Regulation of Organ Size.
Meera Sundaram	Regulation and targets of Ras/ERK signaling in C. elegans

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Genetics of Diabetes and Metabolism

G&E Faculty	Brief Research Description
Klaus Kaestner	Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract.
Mitchell Lazar	Regulation of gene expression and metabolism by nuclear hormone receptors.
Liming Pei	The goal of our research is to understand metabolism and metabolic regulation in both normal physiology and disease states and apply this knowledge to human health and medicine.
Raymond Soccio	Nuclear receptors, transcription factors, lipid metabolism, genetic variation, Fatty liver disease, metabolic syndrome, obesity, diabetes
Doris Stoffers	Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.

Other CAMB Faculty	Brief Research Description
Rex Ahima	Neuroendocrine regulation of body weight and glucose.
Xianxin Hua	Elucidating the critical role of the tumor suppressor Menin in regulation of cell proliferation, leukemia and diabetes; investigating signal transduction and epigenetics co-regulated by transforming growth factor beta (TGF-ß) and Menin.
Michael Pack	* Development of the vertebrate digestive system * Biology and physiology of digestive epithelia and cancers * High throughput small molecule drug screens
Daniel Rader	Genetic regulation of lipid and lipoprotein metabolism and molecular relationship to atherosclerosis.
Patrick Seale	We are particularly interested in early determination and specification events; this involves the commitment of mesenchymal stem cells to a preadipose cell fate. We are also exploring pathways that determine the fate (and thus the function) of different types of fat cells.
Katherine Wellen	My lab is studying cellular metabolism, particularly how metabolic pathways regulate signal transduction and gene expression in cancer and metabolic disease.
Bryan Wolf	Signaling mechanisms of insulin secretion. Cytokines and diabetes.

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Animal Modeling of Human Disease 

G&E Faculty	Brief Research Description
Naiara Aquizu Lopez	Our research interest is to better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders.
Andres Blanco	I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs.
Nancy Bonini	Molecular genetics of neurodegenerative disease.
Edward S. Brodkin	Genetic analysis of social behaviors (aggressive and affiliative behaviors) and related brain phenotypes in mouse models relevant to autism and schizophrenia.
Maja Bucan	Genetic dissection of complex behaviors in mice; functional genomics.
Brian Capell	Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system.
Nancy Cooke	The role of chromatin structure in eukaryotic gene regulation.
Gideon Dreyfuss	RNA-binding proteins, nuclear transport of proteins and mRNAs, RNA processing, neurodegenerative disease, high throughput approaches to drug discovery.
Douglas Epstein	Regulation of Sonic hedgehog signaling in development and disease
David L. Gasser	Genes that affect the immune response
Donna L. George	Our research interests are focused broadly on the molecular pathways governing cellular growth control and their disruption during the initiation and progression of human cancers.
Thomas Jongens	Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification
Klaus Kaestner	Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract.
Yana Kamberov	Evolution of human specific traits; Genetics of skin appendage development and evolution; Mouse models to understand the functional significance of adaptive genetic changes;identification and functional testing of regulatory elements driving human evolution
Brett Kauffman	The role of mitochondrial chromatin organization in gene expression, resistance to damage, and genome transmission.
Erica Korb	Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders
Mitchell Lazar	* Regulation of gene expression and metabolism by nuclear hormone receptors * Mechanism of obesity-associated insulin resistance and diabetes
Aimee Payne	*Genetic and functional characterization of human autoantibody repertoires *Targeted therapy for pemphigus *Regulation of desmosome assembly and disassembly
Nina Luning Prak	Mobile DNA, rearrangement of immunoglobulin genes, regulation of L1 retrotransposition
J. Eric Russell	Control and function of human embryonic globin genes.
Eileen M. Shore	Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes.
Raymond Soccio	Nuclear receptors, transcription factors, lipid metabolism, genetic variation, fatty liver disease, metabolic syndrome, obesity, diabetes
Doris Stoffers	Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Katalin Susztak	Work in my laboratory is aimed toward the understanding of molecular pathways that govern chronic kidney disease development
Zhaolan (Joe) Zhou	Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease

Other CAMB Faculty	Brief Research Description
Lewis Chodosh	Genetically engineered mouse models for breast cancer; Cancer stem cells; Molecular therapeutics; Genomics; Non-invasive imaging.
Jonathan Epstein	Transcriptional regulation of cardiac development and function using mouse models.
David Feldser	Mechanisms of tumor-suppressor gene action; Role of the immune system in tumor suppression; Genome engineering in the mouse; Chemical genetic strategies to modulate tumor suppression
Brad Johnson	Molecular biology of aging, Werner syndrome, telomeres, recombination.
Brian Keith	How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression.
Sarah Millar	Intercellular signals regulating the development of hair follicles, teeth and mammary glands and postnatal hair growth.
Warren Pear	Processes that control normal development and malignant transformation.
Anil Rustgi	Oncogenes, tumor suppressor genes, molecular genetics of GI cancers (colon, pancreatic, upper GI).
Celeste Simon	Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation.

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Transcriptional Gene Regulation

G&E Faculty	Brief Research Description
Michael Atchison	Control of Gene Expression, development, and oncogenesis.
Marisa Bartolomei	Genomic imprinting and X inactivation in mice.
Craig Bassing	My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies
Shelley Berger	Chromatin structure and function in gene regulation; post-translational modifications of transcription factors and histones; genetic, biochemical and structural analysis of chromatin in S. cerevisiae and human cells; role of interrelated factor/histone modifications in cancer and viral infection.
Andres Blanco	I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs.
Gerd Blobel	hematopoiesis, gene expression, transcription factors, chromatin
Roberto Bonasio	Molecular mechanisms of epigenetic memory, Noncoding RNAs, Chromatin biochemistry
Christopher Brown	We are currently focused on massively parallelizing assays that interrogate non-coding DNA function and applying these approaches to the fine-mapping of the causal variants underlying human disease.
Brian Capell	Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system.
Russ Carstens	Study of the molecular mechanisms of alternative splicing.
Douglas Epstein	Regulation of Sonic hedgehog signaling in development and disease
Hua-Ying Fan	Chromatin structure regulation by ATP-dependent chromatin remodelers and its impact on disease; Mechanisms of transcription memory.
Robert Faryabi	Model interplay between mutated transcriptional regulators and epigenetic dysregulation in cancer
Benjamin Garcia	Quantitative Mass Spectrometry Based Proteomics for Characterizing Modified Proteins and Proteomes
Alessandro Gardini	The Gardini lab investigates how global transcription is regulated during cell differentiation and oncogenesis using a variety of genomics and biochemistry approaches.
Donna L. George	Our research interests are focused broadly on the molecular pathways governing cellular growth control and their disruption during the initiation and progression of human cancers.
Casey Greene	Our overarching goal is to transform how we understand complex biological systems by developing and applying computational algorithms that effectively model processes by integrating multiple types of big data from diverse experiments.
Eric Joyce	Form and function of nuclear compartments and chromosome positioning
Klaus Kaestner	Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract.
Brett Kaufman	The role of mitochondrial chromatin organization in gene expression, resistance to damage, and genome transmission.
Erica Korb	Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders
Mitchell Lazar	Regulation of gene expression and metabolism by nuclear hormone receptors.
Frank Lee	Molecular mechanisms of the hypoxic response.
Stephen Liebhaber	Roles of chromatin structure and epigenetic controls in eucaryotic gene activation; Roles of mRNA-protein interactions in control of eucarytic mRNA stability and expression.
Shawn Little	Transcription dynamics; cell fate specification; RNA production, processing, transport, localization
Ronen Marmorstein	Biochemical, biophysical and X-ray crystallographic techniques are employed to study the posttranslational modification of histones and other proteins and the misregulation of such modifications in cancer and metabolic disorders.
John Murray	Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging
John R. Pehrson	Role of histone variants in regulating chromatin structure and function
Jennifer Phillips-Cremins	Epigenetics | Genomics | Systems and Synthetic Bioengineering | Experimental Neuroscience | Molecular and Cellular Engineering
Kavitha Sarma	RNA interactions in epigenetic gene regulation and genome organization
Eileen M. Shore	Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes.
Rebecca Simmons	Developmental programming of adult disease (diabetes, obesity); ß-cell development; role of epigenetics in fetal programming and early embryo/placenta development
Raymond Soccio	Nuclear receptors, transcription factors, lipid metabolism, genetic variation, fatty liver disease, metabolic syndrome, obesity, diabetes
Kai Tan	Model gene regulatory networks in development and disease
Golnaz Vahedi	Epigenetics, Immunology, Human Genetics, Bioinformatics, Computational Biology, Machine-learning
Doris Wagner	Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.
Kenneth Zaret	Mammalian gene regulation, cell differentiation, chromatin structure.
Zhaolan (Joe) Zhou	Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease

Other CAMB Faculty	Brief Research Description
Frederic Barr	Rhabdomyosarcoma (a cancer of the muscle lineage), chromosomal translocations, paired box transcription factors.
Maya Capelson	*Nuclear structure and its role in gene regulation *Spatial organization of the genome *Epigenetic memory of gene expression states
Jonathan Epstein	Transcriptional regulation of cardiac development and function using mouse models.
Brian Keith	How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression.
Melike Lakadamyali	Super-resolution imaging of chromatin structure and epigenetic regulation of gene activity
Mike May	NF-kB signaling in inflammation and cancer.
Michael Parmacek	Transcriptional programs that regulate cardiovascular development.
Celeste Simon	Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation.
Meera Sundaram	Regulation and targets of Ras/ERK signaling in C. elegans

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Post-Transcriptional Gene Regulation

G&E Faculty	Brief Research Description
Naiara Aquizu Lopez	Our research interest is to better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders.
Michael Atchison	Control of Gene Expression, development, and oncogenesis.
Yoseph Barash	The lab develops machine learning algorithms that integrate high-throughput data (RNASeq, CLIPSeq , PIPSeq, etc.) to infer RNA biogenesis and function, followed by experimental verifications of inferred mechanisms.
Russ Carstens	Study of the molecular mechanisms of alternative splicing.
Gideon Dreyfuss	RNA-binding proteins, nuclear transport of proteins and mRNAs, RNA processing, neurodegenerative disease, high throughput approaches to drug discovery.
Brian Gregory	RNA silencing, RNA degradation, RNA stability, microRNAs, small RNAs
Thomas Jongens	Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification
Eric Joyce	Form and function of nuclear compartments and chromosome positioning
Brett Kaufman	The role of mitochondrial chromatin organization in gene expression, resistance to damage, and genome transmission.
Mitchell Lazar	Regulation of gene expression and metabolism by nuclear hormone receptors.
Stephen Liebhaber	Roles of chromatin structure and epigenetic controls in eucaryotic gene activation; Roles of mRNA-protein interactions in control of eucarytic mRNA stability and expression.
Frank Lee	Molecular mechanisms of the hypoxic response
Kristin Lynch	Mechanisms and consequences of alternative pre-mRNA splicing, in particular how splicing patterns change in T cells during an immune response to alter cellular function.
Zissimos Mourelatos	MicroRNAs, RNA interference.
John Murray	Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging
Doris Stoffers	Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Kazuko Nishikura	RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation.
J. Eric Russell	Control and function of human embryonic globin genes.
Jeremy Wilusz	Regulation of noncoding RNA biogenesis and function
Zhaolan (Joe) Zhou	Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease

Other CAMB Faculty	Brief Research Description
Constantinos Koumenis	Tumor hypoxia, Unfolded Protein Response, translational regulation of gene expression.

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Epigenetics and Chromatin

G&E Faculty	Brief Research Description
Michael Atchison	Control of Gene Expression, development, and oncogenesis.
Marisa Bartolomei	Genomic imprinting and X inactivation in mice.
Craig Bassing	My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies
Shelley Berger	Chromatin structure and function in gene regulation; post-translational modifications of transcription factors and histones; genetic, biochemical and structural analysis of chromatin in S. cerevisiae and human cells; role of interrelated factor/histone modifications in cancer and viral infection.
Ben Black	Chromosome inheritance in somatic cells and through the germline, epigenetic and genetic contributions at mammalian centromeres, chromatin structural biochemistry and biophysics, chromatin complexes that signal errors in cell division and DNA damage during the rest of the cell cycle, chromatin assembly, mass spec-based proteomics and biophysical studies of chromosome complexes
Andres Blanco	I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs.
Gerd Blobel	Hematopoiesis, gene expression, transcription factors, chromatin
Roberto Bonasio	Molecular mechanisms of epigenetic memory, Noncoding RNAs, Chromatin biochemistry
Christopher Brown	We are currently focused on massively parallelizing assays that interrogate non-coding DNA function and applying these approaches to the fine-mapping of the causal variants underlying human disease.
Brian Capell	Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system.
Maya Capelson	*Nuclear structure and its role in gene regulation *Spatial organization of the genome *Epigenetic memory of gene expression states
Jennifer Cremins	The Cremins lab investigates the link between three-dimensional organization of genomes and the establishment and maintenance of cellular function.
Hua-Ying Fan	Chromatin structure regulation by ATP-dependent chromatin remodelers and its impact on disease; Mechanisms of transcription memory.
Robert Faryabi	Model interplay between mutated transcriptional regulators and epigenetic dysregulation in cancer
Alessandro Gardini	The Gardini lab investigates how global transcription is regulated during cell differentiation and oncogenesis using a variety of genomics and biochemistry approaches
Eric Joyce	Form and function of nuclear compartments and chromosome positioning
Klaus Kaestner	Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract.
Jennifer Kalish	Understanding and improving detection of epigenetics and mosaicism in human disease
Brett Kaufman	The role of mitochondrial chromatin organization in gene expression, resistance to damage, and genome transmission.
Erica Korb	Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders
Mitchell Lazar	Regulation of gene expression and metabolism by nuclear hormone receptors.
Stephen Liebhaber	Roles of chromatin structure and epigenetic controls in eucaryotic gene activation; Roles of mRNA-protein interactions in control of eucarytic mRNA stability and expression.
John Murray	Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging
John R. Pehrson	Role of histone variants in regulating chromatin structure and function
Kavitha Sarma	RNA interactions in epigenetic gene regulation and genome organization
Eileen M. Shore	Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes.
Rebecca Simmons	Developmental programming of adult disease (diabetes, obesity); ß-cell development; role of epigenetics in fetal programming and early embryo/placenta development
Raymond Soccio	Nuclear receptors, transcription factors, lipid metabolism, genetic variation, fatty liver disease, metabolic syndrome, obesity, diabetes
Doris Stoffers	Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Kai Tan	Model gene regulatory networks in development and disease
Golnaz Vahedi	Epigenetics, Immunology, Human Genetics, Bioinformatics, Computational Biology, Machine-learning
Doris Wagner	Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.
Hao Wu	Epigenomics, DNA methylation and demethylation, Transcriptional control, Single cell analysis, Stem cell biology, Neural and cardiac lineage specification and maturation
Kenneth Zaret	Mammalian gene regulation, cell differentiation, chromatin structure.
Zhaolan Zhou	Epigenetic Control of Genome Function in Brain Development and Disease

Other CAMB Faculty	Brief Research Description
Jonathan Epstein	Transcriptional regulation of cardiac development and function using mouse models.
David Feldser	Mechanisms of tumor-suppressor gene action; Role of the immune system in tumor suppression; Genome engineering in the mouse; Chemical genetic strategies to modulate tumor suppression
Peter Klein	Early vertebrate development, Wnt signal transduction, neuropharmacology of lithium action
Melike Lakadamyali	Super-resolution imaging of chromatin structure and epigenetic regulation of gene activity
Richard Schultz	Egg activation and gene expression in mouse embryos.

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Bioinformatics and Genomics

G&E Faculty	Brief Research Description
Yoseph Barash	The lab develops machine learning algorithms that integrate high-throughput data (RNASeq, CLIPSeq , PIPSeq, etc.) to infer RNA biogenesis and function, followed by experimental verifications of inferred mechanisms.
Ben Black	Chromosome inheritance in somatic cells and through the germline, epigenetic and genetic contributions at mammalian centromeres, chromatin structural biochemistry and biophysics, chromatin complexes that signal errors in cell division and DNA damage during the rest of the cell cycle, chromatin assembly, mass spec-based proteomics and biophysical studies of chromosome complexes
Andres Blanco	I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs.
Roberto Bonasio	Molecular mechanisms of epigenetic memory, Noncoding RNAs, Chromatin biochemistry
Christopher Brown	We are currently focused on massively parallelizing assays that interrogate non-coding DNA function and applying these approaches to the fine-mapping of the causal variants underlying human disease.
Maja Bucan	Genetic dissection of complex behaviors in mice; Functional genomics
Brian Capell	Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system.
Russ Carstens	Study of the molecular mechanisms of alternative splicing.
Alice Chen-Plotkin	I am interested in neurogenerative diseases; my research approach uses genomic-scale screens to identify leads for downstream mechanistic follow-up in cell culture systems.
Jennifer Phillips-Cremins	Epigenetics | Genomics | Systems and Synthetic Bioengineering | Experimental Neuroscience | Molecular and Cellular Engineering
Robert Faryabi	Model interplay between mutated transcriptional regulators and epigenetic dysregulation in cancer
Alessandro Gardini	The Gardini lab investigates how global transcription is regulated during cell differentiation and oncogenesis using a variety of genomics and biochemistry approaches
Struan Grant	My current work continues to primarily investigate disease genomics, with a specific focus on pediatrics
Casey Greene	big data, integrative genomics, precision medicine, bioinformatics, transcriptomics
Hakon Hakonarson	Genetics of common and rare human diseases, using high-throughput sequencing and genotyping approaches.
Eric Joyce	Form and function of nuclear compartments and chromosome positioning
Klaus Kaestner	Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract.
Erica Korb	Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders
Jason Moore	Assessing polygenic risk of disease using electronic health record data
John Murray	Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging
Raymond Soccio	Nuclear receptors, transcription factors, lipid metabolism, genetic variation, fatty liver disease, metabolic syndrome, obesity, diabetes
Doris Stoffers	Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin.
Kai Tan	Model gene regulatory networks in development and disease
Golnaz Vahedi	Epigenetics, Immunology, Human Genetics, Bioinformatics, Computational Biology, Machine-learning
Benjamin Voight	Using statistical genetics, population genetics, and computational biology toward understanding the biological underpinnings and evolutionary history of human phenotypes
Doris Wagner	Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues.
Jeremy Wilusz	Regulation of noncoding RNA biogenesis and function
Kenneth Zaret	Mammalian gene regulation, cell differentiation, chromatin structure.
Zhaolan (Joe) Zhou	Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease

Other CAMB Faculty	Brief Research Description
Frederic Bushman	Virology, HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer.
Sara Cherry	Genetic and mechanistic studies of viral-host interactions.
David Roos	Molecular parasitology, host-pathogen interactions, drug targets & resistance mechanisms, evolution of eukaryotic cells & organellar function, genome databases & database mining, comparative genomics, computational biology, Toxoplasma gondii, Plasmodium falciparum.
Jun Zhu	Quorum Sensing, Bacterial pathogenesis, Biofilms, Vibrio cholerae.

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CAMB Faculty Affiliated with G&E

• Juan Alvarez, Ph.D. 
• Stewart Anderson, M.D.
• Montserrat Anguera, Ph.D.
• Irfan Asangani, Ph.D. 
• Will Bailis, Ph.D. 
• Greg Bashaw, Ph.D. 
• Peter Choi, Ph.D. 
• Crystal Conn, Ph.D. 
• Stephen Dinardo, Ph.D. 
• Dennis Discher, Ph.D. 
• Yi Fan, M.D., Ph.D. 
• David Feldser, Ph.D.
• Aime Franco, Ph.D. 
• David Frank, M.D., Ph.D.
• Paul Gadue, Ph.D.
• Matthew Good, Ph.D.
• Michael Granato, Ph.D.
• Marie Guerraty, M.D., Ph.D. 
• Kathryn Hamilton, Ph.D.
• Sarah Henrickson, M.D., Ph.D.
• Rajan Jain, M.D. 
• Chengcheng Jin, Ph.D.
• Kelly Jordan-Sciutto, Ph.D.
• Yana Kamberov, Ph.D.
• Daniel Kelly, M.D. 
• Peter Klein, M.D., Ph.D. 
• Melike Lakadamyali, Ph.D.
• Michael Lampson, Ph.D.
• Edward Lee, M.D., Ph.D.
• Thomas Leung, M.D., Ph.D. 
• Fanxin Long, Ph.D.
• Jonathan Miner, M.D., Ph.D. 
• Mustafa Mir, Ph.D.
• Andrew Modzelewski, Ph.D.
• Foteini Mourkioti, Ph.D.
• Kiran Musunuru, M.D., Ph.D., M.P.H., M.L.
• Katherine Nathanson, M.D.
• Vikram Paralkar, M.D.
• Liming Pei, Ph.D. 
• Benjamin Prosser, Ph.D. 
• Bushra Raj, Ph.D. 
• Stefano Rivella, Ph.D. 
• Kotaro Sasaki, M.D. Ph.D.
• Patrick Seale, Ph.D.
• Sydney Shaffer, M.D. Ph.D. 
• Junwei Shi, Ph.D.
• Arndt Siekmann, Ph.D. 
• Hongjun Song, Ph.D. 
• Yuanquan Song, Ph.D. 
• Ben Stanger, M.D. Ph.D. 
• Meera Sundaram, Ph.D. 
• Christopher Thom, M.D., Ph.D. 
• Andrei Thomas-Tikhonenko, Ph.D. 
• Paul Titchenell, Ph.D. 
• Liling Wan, Ph.D. 
• Evan Weber, Ph.D. 
• Kathryn Wellen, Ph.D. 

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For information on how to apply for CAMB Faculty membership, please see the CAMB Bylaws.