Genetics and Epigenetics Faculty
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Genetics and Epigenetics
Click the faculty member's name to see more detailed information.
Faculty
Faculty areas of research in G&E can be broken up into the following categories:
| G&E Faculty | Brief Research Description |
|---|---|
| Montserrat Anguera |
Epigenetic mechanisms of X-Chromosome Inactivation in immune cells & immune-related diseases |
| Naiara Aquizu Lopez | Our research interest is to better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders. |
| Ben Black | Chromosome inheritance in somatic cells and through the germline, epigenetic and genetic contributions at mammalian centromeres, chromatin structural biochemistry and biophysics, chromatin complexes that signal errors in cell division and DNA damage during the rest of the cell cycle, chromatin assembly, mass spec-based proteomics and biophysical studies of chromosome complexes |
| Kahlilia Blanco |
Epigenetics, noncoding RNAs, and mitochondrial function in neuroprotection and stroke and cerebrovascular disease pathology |
| Maja Bucan | Genetic dissection of complex behaviors in mice; Functional genomics |
| Alice Chen-Plotkin | I am interested in neurodegenerative diseases; my research approach uses genomic-scale screens to identify leads for downstream mechanistic follow-up in cell culture systems. |
| Gideon Dreyfuss | RNA-binding proteins, nuclear transport of proteins and mRNAs, RNA processing, neurodegenerative disease, high throughput approaches to drug discovery. |
| Michael Gandal |
The Gandal Lab has three main areas of focus: (1) gene discovery for neurodevelopmental, psychiatric disorders in large-scale biobanks; (2) developing statistical genetic tools and constructing large-scale functional genomic resources using human brain tissue samples to prioritize GWAS mechanisms; (3) using single-cell and long-read sequencing technology to characterize transcript-isoform diversity during human brain development and disease. |
| Struan Grant | Utilizing high-throughput genotyping and sequencing technologies, combined with statistical and bioinformatic approaches, my goals include unraveling genomic puzzles related to childhood obesity, pediatric bone strength determination, early onset diabetes and cancer. |
| Hakon Hakonarson | Genetics of common and rare human diseases, using high-throughput sequencing and genotyping approaches |
| Jennifer Kalish |
Understanding and improving detection of epigenetics and mosaicism in human disease |
| Bryson Katona | Understanding cancer risks, prevention strategies, and therapeutic mechanisms for hereditary gastrointestinal cancer and polyposis predisposition syndromes |
| Rachel Kember | The lab seeks to identify the complex phenotypic and genomic interactions that lead to substance use and psychiatric disease, using computational genetics methods in electronic health record datasets linked to biobanks. |
| Edward Lee | Neurogenerative disease pathology, genetics and epigenetics, RNA misprocessing, and human tissue transcriptomics |
| Vikram Paralkar | Epigenetics, Transcription, Ribosomal DNA/RNA, Bioinformatics, Hematopoiesis, Leukemia |
| Nina Luning Prak | Mobile DNA, rearrangement of immunoglobulin genes, regulation of L1 retrotransposition |
| Andrew Modzelewski | Investigating the role and regulation of retrotransposons in development and disease |
| Aimee Payne | Genetic and functional characterization of human autoantibody repertoires; Targeted therapy for pemphigus ; Regulation of desmosome assembly and disassembly |
| Daniel Rader | Genetic regulation of lipid and lipoprotein metabolism and molecular relationship to atherosclerosis. |
| J. Eric Russell | Control and function of human embryonic globin genes. |
| Eileen M. Shore | Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes. |
| Nancy Spinner | Human Genetics, Notch signaling in human disease, Alagille syndrome, human disease gene identifcation by mapping deletions. |
|
Alanna Strong |
Gene discovery, hepatobiliary disease, cystic kidney disease, ciliopathy syndromes, tubulogenesis |
| Kai Tan | Model gene regulatory networks in development and disease |
| Sarah Tishkoff | Human Genetics, complex disease, human evolution, infectious disease, malaria, evolutionary biology, natural selection, adaptation. |
| Golnaz Vahedi | Epigenetics, Immunology, Human Genetics, Bioinformatics, Computational Biology, Machine-learning |
| Benjamin Voight | Using statistical genetics, population genetics, and computational biology toward understanding the biological underpinnings and evolutionary history of human phenotypes |
| Kai Wang | We develop genomics and bioinformatics methods to understand the genetic basis of human diseases, with specific focus on the use of long-read sequencing techniques and the integration of multimodal data from electronic health records |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Dwight Stambolian | Gene discovery of complex and monogenic disorders. |
| G&E Faculty | Brief Research Description |
|---|---|
| Nancy Bonini | Molecular genetics of neurodegenerative disease. |
| Brian Gregory | RNA silencing, RNA degradation, RNA stability, microRNAs, small RNAs |
| John Murray | Developmental regulatory networks, dynamics of embryonic gene expression, and single-cell methods in C. elegans |
| David Raizen | The regulation and purpose of sleep-like behavior in C. elegans. |
| Arjun Raj | RNA systems biology, particular as related to non-coding RNAs and cancer biology. |
| Meera Sundaram | Tubulogenesis and Epithelial matrix biology in C. elegans |
| G&E Faculty | Brief Research Description |
|---|---|
| Michael Atchison | Control of Gene Expression, development, and oncogenesis. |
| Thomas Jongens | Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification |
| Eric Joyce | Form and function of nuclear compartments and chromosome positioning |
| Amita Sehgal | Molecular basis of behavior |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Greg Bashaw | Signaling mechanisms that function during attractive and repulsive axon guidance. |
| Sara Cherry | Genetic and mechanistic studies of viral-host interactions. |
| Steve Dinardo | Stem cell function; developmental patterning. |
| G&E Faculty | Brief Research Description |
|---|---|
| Montserrat Anguera |
Epigenetic mechanisms of X-Chromosome Inactivation in immune cells & immune-related diseases |
| Michael Atchison | Control of Gene Expression, development, and oncogenesis. |
| Marisa Bartolomei |
Genomic imprinting and X inactivation in mice. |
| Craig Bassing | My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies |
| Ben Black | Chromosome inheritance in somatic cells and through the germline, epigenetic and genetic contributions at mammalian centromeres, chromatin structural biochemistry and biophysics, chromatin complexes that signal errors in cell division and DNA damage during the rest of the cell cycle, chromatin assembly, mass spec-based proteomics and biophysical studies of chromosome complexes |
| Kahlilia Blanco |
Epigenetics, noncoding RNAs, and mitochondrial function in neuroprotection and stroke and cerebrovascular disease pathology |
| Edward S. Brodkin | Genetic analysis of social behaviors (aggressive and affiliative behaviors) and related brain phenotypes in mouse models relevant to autism and schizophrenia. |
| Lewis Chodosh | Genetically engineered mouse models for breast cancer; Cancer stem cells; Molecular therapeutics; Genomics; Non-invasive imaging. |
| Douglas Epstein | Regulation of Sonic hedgehog signaling in development and disease |
| Jonathan Epstein | Transcriptional regulation of cardiac development and function using mouse models. |
| Xianxin Hua | The critical role of the tumor suppressor Menin in regulation of cell proliferation, apoptosis, and genome stability. Signal transduction mediated by transforming growth factor beta (TGF-b). |
| Olena Jacenko | Molecular mechanisms of skeletal development and blood cell differentiation. |
| Brad Johnson | Molecular biology of aging, Werner syndrome, telomeres, recombination. |
| Eric Joyce | Form and function of nuclear compartments and chromosome positioning |
| Klaus Kaestner | Dr. Kaestner’s lab is employing modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract. |
| Yana Kamberov | Evolution of human specific traits; Genetics of skin appendage development and evolution; Mouse models to understand the functional significance of adaptive genetic changes;identification and functional testing of regulatory elements driving human evolution |
| Anna Kashina | Protein modifications, mouse genetics, cancer, cytoskeleton, cardiovascular development, angiogenesis. |
| Jonathan Katz | Transcriptional regulation, epithelial homeostasis, gastrointestinal carcinogenesis |
| Frank Lee | Molecular mechanisms of the hypoxic response. |
| Andrew Modzelewski | Investigating the role and regulation of retrotransposons in development and disease |
| Ed Morrisey | Lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors. |
| Kazuko Nishikura | RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation. |
| Vikram Paralkar | Epigenetics, Transcription, Ribosomal DNA/RNA, Bioinformatics, Hematopoiesis, Leukemia |
| Michael Parmacek | Transcriptional programs that regulate cardiovascular development. |
| Aimee Payne | *Genetic and functional characterization of human autoantibody repertoires *Targeted therapy for pemphigus *Regulation of desmosome assembly and disassembly |
| Nina Luning Prak | mobile DNA, rearrangement of immunoglobulin genes, regulation of L1 retrotransposition |
| Daniel Rader | Genetic regulation of lipid and lipoprotein metabolism and molecular relationship to atherosclerosis. |
| J. Eric Russell | Control and function of human embryonic globin genes. |
| Celeste Simon | Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation. |
| Nancy Speck | Hematopoietic stem cells and leukemia using mouse models |
| Ben Stanger | Organogenesis, Stem Cells, Pancreatic Cancer, Regulation of Organ Size. |
| Doris Stoffers | Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
| Katalin Susztak | Work in my laboratory is aimed toward the understanding of molecular pathways that govern chronic kidney disease development |
| Kenneth Zaret | Mammalian gene regulation, cell differentiation, chromatin structure. |
| Zhaolan (Joe) Zhou | Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease |
| G&E Faculty | Brief Research Description |
|---|---|
| Brian Gregory | RNA silencing, RNA degradation, RNA stability, microRNAs, small RNAs |
| Doris Wagner | Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues. |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Scott Poethig | Regulation of developmental timing and organ polarity in plants. |
| G&E Faculty | Brief Research Description |
|---|---|
| Shelley Berger | Chromatin structure and function in gene regulation; post-translational modifications of transcription factors and histones; genetic, biochemical and structural analysis of chromatin in S. cerevisiae and human cells; role of interrelated factor/histone modifications in cancer and viral infection. |
| Kara Bernstein | Regulation of DNA repair, recombination, and replication in cancer |
| Erfei Bi | Development of cell polarity and control of cytokinesis in budding yeast. |
| Andrew Dancis | Iron transport into mitochondria, Heme synthesis, Fe-S cluster biogenesis, Yeast genetics, and Sideroblastic anemia |
| Wei Guo | The molecular basis for polarized exocytosis and how exocytosis contributes to polarized cell growth and morphogenesis. |
| Brad Johnson | Molecular biology of aging, Werner syndrome, telomeres, recombination. |
| Frank Luca | Yeast and mammalian cell cycle regulation; Cytokinesis. Daughter cell-specific gene expression; Polarized growth Mitotic Exit Network (MEN); Regulation of Ace2-dependent transcription and Morphogenesis (RAM). |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Frederic Bushman | Virology, HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer. |
| Sara Cherry | Genetic and mechanistic studies of viral-host interactions. |
| Mark Goulian | Bacterial regulatory circuits and signal transduction |
| Elizabeth Grice | Genomic approaches to understand host-microbe interactions at the cutaneous surface in health and disease. |
| Paul Lieberman | Genome maintenance and gene expression; Gammaherpesviruses and oncogenesis; Telomere Biology, Chromatin structure and genome stability; Transcription regulation. |
| Mechthild Pohlschroder | Prokaryotic Protein Translocation across Hydrophobic Membranes and Their Substrates. |
| David Roos | Molecular parasitology, host-pathogen interactions, drug targets & resistance mechanisms, evolution of eukaryotic cells & organellar function, genome databases & database mining, comparative genomics, computational biology, Toxoplasma gondii, Plasmodium falciparum. |
| Matthew Weitzman | Virology, Virus Replication, DNA Damage and Repair, Genome Instability, Viral Vectors |
| Jun Zhu | Quorum Sensing, Bacterial pathogenesis, Biofilms, Vibrio cholerae. |
| G&E Faculty | Brief Research Description |
|---|---|
| Naiara Aquizu Lopez | Our research interest is to better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders. |
| Michael Atchison | Control of Gene Expression, development, and oncogenesis. |
| Craig Bassing | My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies |
| Roberto Bonasio | Epigenetics, chromatin, noncoding RNAs, ants |
| Gerd Blobel | Hematopoiesis, gene expression, transcription factors, chromatin |
| Brian Capell | Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system. |
| Jennifer Cremins | The Cremins lab investigates the link between three-dimensional organization of genomes and the establishment and maintenance of cellular function. |
| Douglas Epstein | Regulation of Sonic hedgehog signaling in development and disease |
| Michael Gandal |
The Gandal Lab has three main areas of focus: (1) gene discovery for neurodevelopmental, psychiatric disorders in large-scale biobanks; (2) developing statistical genetic tools and constructing large-scale functional genomic resources using human brain tissue samples to prioritize GWAS mechanisms; (3) using single-cell and long-read sequencing technology to characterize transcript-isoform diversity during human brain development and disease. |
| Thomas Jongens | Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification |
| Eric Joyce | Form and function of nuclear compartments and chromosome positioning |
| Yana Kamberov | Evolution of human specific traits; Genetics of skin appendage development and evolution; Mouse models to understand the functional significance of adaptive genetic changes;identification and functional testing of regulatory elements driving human evolution |
| Andrew Modzelewski | Investigating the role and regulation of retrotransposons in development and disease |
| Ed Morrisey | Lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors. |
| Mary Mullins | BMP signal transduction; molecular mechanisms of cell specification establishment of the vertebrate body plan via maternal control mechanisms. |
| John Murray | Combinatorial control of transcription and cell fate specification, C. elegans development, cellular resolution live imaging |
| Kazuko Nishikura | RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation. |
| Aimee Payne | *Genetic and functional characterization of human autoantibody repertoires *Targeted therapy for pemphigus *Regulation of desmosome assembly and disassembly |
| Nancy Spinner | Human Genetics, Notch signaling in human disease, Alagille syndrome, human disease gene identifcation by mapping deletions. |
| Eileen M. Shore | Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes. |
| Doris Stoffers | Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
|
Alanna Strong |
Gene discovery, hepatobiliary disease, cystic kidney disease, ciliopathy syndromes, tubulogenesis |
| Meera Sundaram | Tubulogenesis and Epithelial matrix biology in C. elegans |
| Katalin Susztak | Work in my laboratory is aimed toward the understanding of molecular pathways that govern chronic kidney disease development. |
| Kai Tan | Model gene regulatory networks in development and disease |
| Doris Wagner | Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues. |
| Kenneth Zaret | Mammalian gene regulation, cell differentiation, chromatin structure. |
| Zhaolan (Joe) Zhou | Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Greg Bashaw | Signaling mechanisms that function during attractive and repulsive axon guidance. |
| Steve DiNardo | Stem Cell Function; developmental patterning. |
| Jonathan Epstein | Transcriptional regulation of cardiac development and function using mouse models. |
| Michael Granato | Axonal guidance and motor behavior regulation in the zebrafish. |
| Olena Jacenko | Molecular mechanisms of skeletal development and blood cell differentiation. |
| Brian Keith | How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression. |
| Michael Pack | Genetic analysis of vertebrate digestive organ development using the zebrafish. |
| Micahel Parmacek | Transcriptional programs that regulate cardiovascular development. |
| Scott Poethig | Regulation of developmental timing and organ polarity in plants. |
| Patrick Seale | Transcriptional control of adipocyte formation and function |
| Celeste Simon | Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation. |
| Nancy Speck | Hematopoietic stem cells and leukemia using mouse models |
| Ben Stanger | Organogenesis, Stem Cells, Pancreatic Cancer, Regulation of Organ Size. |
| G&E Faculty | Brief Research Description |
|---|---|
| Kahlilia Blanco |
Epigenetics, noncoding RNAs, and mitochondrial function in neuroprotection and stroke and cerebrovascular disease pathology |
| Roberto Bonasio | Epigenetics, chromatin, noncoding RNAs, ants |
| Nancy Bonini | Molecular genetics of neurodegenerative disease. |
| Edward S. Brodkin | Genetic analysis of social behaviors (aggressive and affiliative behaviors) and related brain phenotypes in mouse models relevant to autism and schizophrenia. |
| Maja Bucan | Genetic dissection of complex behaviors in mice; Functional genomics |
| Alice Chen-Plotkin | I am interested in neurodegenerative diseases; my research approach uses genomic-scale screens to identify leads for downstream mechanistic follow-up in cell culture systems. |
| Douglas Epstein | Regulation of Sonic hedgehog signaling in development and disease |
| Michael Gandal |
The Gandal Lab has three main areas of focus: (1) gene discovery for neurodevelopmental, psychiatric disorders in large-scale biobanks; (2) developing statistical genetic tools and constructing large-scale functional genomic resources using human brain tissue samples to prioritize GWAS mechanisms; (3) using single-cell and long-read sequencing technology to characterize transcript-isoform diversity during human brain development and disease. |
| Thomas Jongens | Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification |
| Rachel Kember | The lab seeks to identify the complex phenotypic and genomic interactions that lead to substance use and psychiatric disease, using computational genetics methods in electronic health record datasets linked to biobanks. |
| Erica Korb | Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders |
| Edward Lee | Neurogenerative disease pathology, genetics and epigenetics, RNA misprocessing, and human tissue transcriptomics |
| Kazuko Nishikura | RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation. |
| David Raizen | The regulation and purpose of sleep-like behavior in C. elegans |
| Amita Sehgal | Molecular basis of behavior |
| Franz Weber | We employ a multidisciplinary approach to study the regulation and function of REM sleep and seek to mechanistically understand how this brain state influences our emotions and behavior in health and disease. |
| Zhaolan (Joe) Zhou | Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Greg Bashaw | Signaling mechanisms that function during attractive and repulsive axon guidance. |
| Michael Granato | Axonal guidance and motor behavior regulation in the zebrafish. |
| G&E Faculty | Brief Research Description |
|---|---|
| Yoseph Barash | The lab develops machine learning algorithms that integrate high-throughput data (RNASeq, CLIPSeq , PIPSeq, etc.) to infer RNA biogenesis and function, followed by experimental verifications of inferred mechanisms. |
| Craig Bassing | My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies |
| Kara Bernstein | Regulation of DNA repair, recombination, and replication in cancer |
| Andres Blanco | I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs. |
| Gerd Blobel | Hematopoiesis, gene expression, transcription factors, chromatin |
| Garrett Brodeur | Molecular biology and genetics of childhood cancer, especially neuroblastoma. |
| Brian Capell | Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system. |
| Lewis Chodosh | Genetically engineered mouse models for breast cancer; Cancer stem cells; Molecular therapeutics; Genomics; Non-invasive imaging. |
| Douglas Epstein | Regulation of Sonic hedgehog signaling in development and disease |
| Robert Faryabi | Develop analytical methods for precision cancer genomics. |
| David Feldser | Mechanisms of tumor-suppressor gene action; Role of the immune system in tumor suppression; Genome engineering in the mouse; Chemical genetic strategies to modulate tumor suppression |
| Pablo Gonzalez-Camara |
The focus of the Camara lab is the application and development of computational methods to study cellular heterogeneity and its role in cancer progression |
| Jennifer Kalish | Understanding and improvingdetection of epigenetics and mosaicismin human disease |
| Bryson Katona | Understanding cancer risks, prevention strategies, and therapeutic mechanisms for hereditary gastrointestinal cancer and polyposis predisposition syndromes |
| Jonathan Katz | Transcriptional regulation, epithelial homeostasis, gastrointestinal carcinogenesis |
| Brian Keith | How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression. |
| Maureen Murphy | p53 tumor suppressor, HSP70 chaperone, autophagy, programmed cell death. Keywords: Cancer Genetics and Signal Transduction, Genetics of diabetes and metabolism, Animal modeling of human disease |
| Warren Pear | Processes that control normal development and malignant transformation. |
| Anil Rustgi | Oncogenes, tumor suppressor genes, molecular genetics of GI cancers (colon, pancreatic, upper GI). |
| Sydney Shaffer | Systems biology, genomics, lineage tracing, and spatial transcriptomics applied to tissues and cancer |
| Junwei Shi | CRISPR genome editing, cancer functional genomics, transcriptional and epigenetic regulation |
| Celeste Simon | Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation. |
| Ben Stanger | Organogenesis, Stem Cells, Pancreatic Cancer, Regulation of Organ Size. |
| Doris Stoffers | Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
| Meera Sundaram | Regulation and targets of Ras/ERK signaling in C. elegans |
| Kai Tan | Model gene regulatory networks in development and disease |
| Doris Wagner | Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues. |
| G&E Faculty | Brief Research Description |
|---|---|
| Xianxin Hua | Elucidating the critical role of the tumor suppressor Menin in regulation of cell proliferation, leukemia and diabetes; investigating signal transduction and epigenetics co-regulated by transforming growth factor beta (TGF-ß) and Menin. |
| Klaus Kaestner | Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract. |
| Mitchell Lazar | Regulation of gene expression and metabolism by nuclear hormone receptors. |
| Michael Pack | * Development of the vertebrate digestive system * Biology and physiology of digestive epithelia and cancers * High throughput small molecule drug screens |
| Liming Pei | The goal of our research is to understand metabolism and metabolic regulation in both normal physiology and disease states and apply this knowledge to human health and medicine. |
| Daniel Rader | Genetic regulation of lipid and lipoprotein metabolism and molecular relationship to atherosclerosis. |
| Patrick Seale | We are particularly interested in early determination and specification events; this involves the commitment of mesenchymal stem cells to a preadipose cell fate. We are also exploring pathways that determine the fate (and thus the function) of different types of fat cells. |
| Raymond Soccio | Nuclear receptors, transcription factors, lipid metabolism, genetic variation, Fatty liver disease, metabolic syndrome, obesity, diabetes |
| Doris Stoffers | Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
| Katherine Wellen | My lab is studying cellular metabolism, particularly how metabolic pathways regulate signal transduction and gene expression in cancer and metabolic disease. |
| G&E Faculty | Brief Research Description |
|---|---|
| Montserrat Anguera |
Epigenetic mechanisms of X-Chromosome Inactivation in immune cells & immune-related diseases |
| Naiara Aquizu Lopez | Our research interest is to better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders. |
| Andres Blanco | I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs. |
| Kahlilia Blanco |
Epigenetics, noncoding RNAs, and mitochondrial function in neuroprotection and stroke and cerebrovascular disease pathology |
| Nancy Bonini | Molecular genetics of neurodegenerative disease. |
| Edward S. Brodkin | Genetic analysis of social behaviors (aggressive and affiliative behaviors) and related brain phenotypes in mouse models relevant to autism and schizophrenia. |
| Maja Bucan | Genetic dissection of complex behaviors in mice; functional genomics. |
| Brian Capell | Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system. |
| Lewis Chodosh | Genetically engineered mouse models for breast cancer; Cancer stem cells; Molecular therapeutics; Genomics; Non-invasive imaging. |
| Gideon Dreyfuss | RNA-binding proteins, nuclear transport of proteins and mRNAs, RNA processing, neurodegenerative disease, high throughput approaches to drug discovery. |
| Douglas Epstein | Regulation of Sonic hedgehog signaling in development and disease |
| David Feldser | Mechanisms of tumor-suppressor gene action; Role of the immune system in tumor suppression; Genome engineering in the mouse; Chemical genetic strategies to modulate tumor suppression |
| Thomas Jongens | Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification |
| Klaus Kaestner | Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract. |
| Yana Kamberov | Evolution of human specific traits; Genetics of skin appendage development and evolution; Mouse models to understand the functional significance of adaptive genetic changes;identification and functional testing of regulatory elements driving human evolution |
| Bryson Katona | Using mouse models of hereditary gastrointestinal cancer and polyposis predisposition syndromes to understand cancer risks, prevention strategies, and therapeutic mechanisms for these syndromes |
| Jonathan Katz | Transcriptional regulation, epithelial homeostasis, gastrointestinal carcinogenesis |
| Erica Korb | Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders |
| Mitchell Lazar | * Regulation of gene expression and metabolism by nuclear hormone receptors * Mechanism of obesity-associated insulin resistance and diabetes |
| Aimee Payne | *Genetic and functional characterization of human autoantibody repertoires *Targeted therapy for pemphigus *Regulation of desmosome assembly and disassembly |
| Nina Luning Prak | Mobile DNA, rearrangement of immunoglobulin genes, regulation of L1 retrotransposition |
| J. Eric Russell | Control and function of human embryonic globin genes. |
| Eileen M. Shore | Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes. |
| Raymond Soccio | Nuclear receptors, transcription factors, lipid metabolism, genetic variation, fatty liver disease, metabolic syndrome, obesity, diabetes |
| Doris Stoffers | Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
| Meera Sundaram | Tubulogenesis and Epithelial matrix biology in C. elegans |
| Katalin Susztak | Work in my laboratory is aimed toward the understanding of molecular pathways that govern chronic kidney disease development |
| Zhaolan (Joe) Zhou | Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Jonathan Epstein | Transcriptional regulation of cardiac development and function using mouse models. |
| Brad Johnson | Molecular biology of aging, Werner syndrome, telomeres, recombination. |
| Brian Keith | How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression. |
| Warren Pear | Processes that control normal development and malignant transformation. |
| Celeste Simon | Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation. |
| G&E Faculty | Brief Research Description |
|---|---|
| Montserrat Anguera |
Epigenetic mechanisms of X-Chromosome Inactivation in immune cells & immune-related diseases |
| Michael Atchison | Control of Gene Expression, development, and oncogenesis. |
| Marisa Bartolomei | Genomic imprinting and X inactivation in mice. |
| Craig Bassing | My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies |
| Shelley Berger | Chromatin structure and function in gene regulation; post-translational modifications of transcription factors and histones; genetic, biochemical and structural analysis of chromatin in S. cerevisiae and human cells; role of interrelated factor/histone modifications in cancer and viral infection. |
| Andres Blanco | I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs. |
| Kahlilia Blanco |
Epigenetics, noncoding RNAs, and mitochondrial function in neuroprotection and stroke and cerebrovascular disease pathology |
| Gerd Blobel | hematopoiesis, gene expression, transcription factors, chromatin |
| Roberto Bonasio | Molecular mechanisms of epigenetic memory, Noncoding RNAs, Chromatin biochemistry |
| Brian Capell | Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system. |
| Douglas Epstein | Regulation of Sonic hedgehog signaling in development and disease |
| Jonathan Epstein | Transcriptional regulation of cardiac development and function using mouse models. |
| Robert Faryabi | Model interplay between mutated transcriptional regulators and epigenetic dysregulation in cancer |
| Michael Gandal |
The Gandal Lab has three main areas of focus: (1) gene discovery for neurodevelopmental, psychiatric disorders in large-scale biobanks; (2) developing statistical genetic tools and constructing large-scale functional genomic resources using human brain tissue samples to prioritize GWAS mechanisms; (3) using single-cell and long-read sequencing technology to characterize transcript-isoform diversity during human brain development and disease. |
| Alessandro Gardini | The Gardini lab investigates how global transcription is regulated during cell differentiation and oncogenesis using a variety of genomics and biochemistry approaches. |
| Eric Joyce | Form and function of nuclear compartments and chromosome positioning |
| Klaus Kaestner | Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract. |
| Jonathan Katz | Transcriptional regulation, epithelial homeostasis, gastrointestinal carcinogenesis |
| Erica Korb | Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders |
| Melike Lakadamyali | Super-resolution imaging of chromatin structure and epigenetic regulation of gene activity |
| Mitchell Lazar | Regulation of gene expression and metabolism by nuclear hormone receptors. |
| Frank Lee | Molecular mechanisms of the hypoxic response. |
| Ronen Marmorstein | Biochemical, biophysical and X-ray crystallographic techniques are employed to study the posttranslational modification of histones and other proteins and the misregulation of such modifications in cancer and metabolic disorders. |
| Andrew Modzelewski | Investigating the role and regulation of retrotransposons in development and disease |
| John Murray | Developmental regulatory networks, dynamics of embryonic gene expression, and single-cell methods in C. elegans |
| Vikram Paralkar | Epigenetics, Transcription, Ribosomal DNA/RNA, Bioinformatics, Hematopoiesis, Leukemia |
| Jennifer Phillips-Cremins | Epigenetics | Genomics | Systems and Synthetic Bioengineering | Experimental Neuroscience | Molecular and Cellular Engineering |
| Kavitha Sarma | RNA interactions in epigenetic gene regulation and genome organization |
| Sydney Shaffer | Systems biology, genomics, lineage tracing, and spatial transcriptomics applied to tissues and cancer |
| Junwei Shi | CRISPR genome editing, cancer functional genomics, transcriptional and epigenetic regulation |
| Eileen M. Shore | Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes. |
| Rebecca Simmons | Developmental programming of adult disease (diabetes, obesity); ß-cell development; role of epigenetics in fetal programming and early embryo/placenta development |
|
Alanna Strong |
Gene discovery, hepatobiliary disease, cystic kidney disease, ciliopathy syndromes, tubulogenesis |
| Meera Sundaram | Regulation and targets of Ras/ERK signaling in C. elegans |
| Kai Tan | Model gene regulatory networks in development and disease |
| Golnaz Vahedi | Epigenetics, Immunology, Human Genetics, Bioinformatics, Computational Biology, Machine-learning |
| Doris Wagner | Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues. |
| Kenneth Zaret | Mammalian gene regulation, cell differentiation, chromatin structure. |
| Zhaolan (Joe) Zhou | Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Brian Keith | How cells and tissues adapt to oxygen deprivation (hypoxia) by modifying gene expression. |
| Michael Parmacek | Transcriptional programs that regulate cardiovascular development. |
| Celeste Simon | Hematopoiesis, angiogenesis, tumorigenesis, and cellular responses to oxygen deprivation. |
| G&E Faculty | Brief Research Description |
|---|---|
| Naiara Aquizu Lopez | Our research interest is to better understand human brain complexity in health and disease, with the ultimate goal to uncover therapeutic targets for neurological disorders. |
| Michael Atchison | Control of Gene Expression, development, and oncogenesis. |
| Yoseph Barash | The lab develops machine learning algorithms that integrate high-throughput data (RNASeq, CLIPSeq , PIPSeq, etc.) to infer RNA biogenesis and function, followed by experimental verifications of inferred mechanisms. |
| Kahlilia Blanco |
Epigenetics, noncoding RNAs, and mitochondrial function in neuroprotection and stroke and cerebrovascular disease pathology |
| Gideon Dreyfuss | RNA-binding proteins, nuclear transport of proteins and mRNAs, RNA processing, neurodegenerative disease, high throughput approaches to drug discovery. |
| Brian Gregory | RNA silencing, RNA degradation, RNA stability, microRNAs, small RNAs |
| Thomas Jongens | Modeling Fragile X Mental Retardation in Drosophila; Germ Cell Specification |
| Eric Joyce | Form and function of nuclear compartments and chromosome positioning |
| Mitchell Lazar | Regulation of gene expression and metabolism by nuclear hormone receptors. |
| Frank Lee | Molecular mechanisms of the hypoxic response |
| Kristin Lynch | Mechanisms and consequences of alternative pre-mRNA splicing, in particular how splicing patterns change in T cells during an immune response to alter cellular function. |
| Zissimos Mourelatos | MicroRNAs, RNA interference. |
| John Murray | Developmental regulatory networks, dynamics of embryonic gene expression, and single-cell methods in C. elegans |
| Doris Stoffers | Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
| Kazuko Nishikura | RNA metabolism/processing. RNA editing, RNAi mechanism, apoptosis, cell cycle regulation. |
| J. Eric Russell | Control and function of human embryonic globin genes. |
| Zhaolan (Joe) Zhou | Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease |
| Other CAMB Faculty | Brief Research Description |
|---|---|
| Constantinos Koumenis | Tumor hypoxia, Unfolded Protein Response, translational regulation of gene expression. |
| G&E Faculty | Brief Research Description |
|---|---|
| Montserrat Anguera |
Epigenetic mechanisms of X-Chromosome Inactivation in immune cells & immune-related diseases |
| Michael Atchison | Control of Gene Expression, development, and oncogenesis. |
| Marisa Bartolomei | Genomic imprinting and X inactivation in mice. |
| Craig Bassing | My lab uses mice as a model to elucidate genetic, epigenetic, and signaling mechanisms by which organisms establish genetic diversity of lymphocyte antigen receptor genes while suppressing inherent hazards of autoimmunity and lymphoid malignancies |
| Shelley Berger | Chromatin structure and function in gene regulation; post-translational modifications of transcription factors and histones; genetic, biochemical and structural analysis of chromatin in S. cerevisiae and human cells; role of interrelated factor/histone modifications in cancer and viral infection. |
| Kara Bernstein | Regulation of DNA repair, recombination, and replication in cancer |
| Ben Black | Chromosome inheritance in somatic cells and through the germline, epigenetic and genetic contributions at mammalian centromeres, chromatin structural biochemistry and biophysics, chromatin complexes that signal errors in cell division and DNA damage during the rest of the cell cycle, chromatin assembly, mass spec-based proteomics and biophysical studies of chromosome complexes |
| Andres Blanco | I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs. |
| Kahlilia Blanco |
Epigenetics, noncoding RNAs, and mitochondrial function in neuroprotection and stroke and cerebrovascular disease pathology |
| Gerd Blobel | Hematopoiesis, gene expression, transcription factors, chromatin |
| Roberto Bonasio | Molecular mechanisms of epigenetic memory, Noncoding RNAs, Chromatin biochemistry |
| Brian Capell | Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system. |
| Maya Capelson | *Nuclear structure and its role in gene regulation *Spatial organization of the genome *Epigenetic memory of gene expression states |
| Jennifer Cremins | The Cremins lab investigates the link between three-dimensional organization of genomes and the establishment and maintenance of cellular function. |
| Jonathan Epstein | Transcriptional regulation of cardiac development and function using mouse models. |
| Robert Faryabi | Model interplay between mutated transcriptional regulators and epigenetic dysregulation in cancer |
| David Feldser | Mechanisms of tumor-suppressor gene action; Role of the immune system in tumor suppression; Genome engineering in the mouse; Chemical genetic strategies to modulate tumor suppression |
| Alessandro Gardini | The Gardini lab investigates how global transcription is regulated during cell differentiation and oncogenesis using a variety of genomics and biochemistry approaches |
| Eric Joyce | Form and function of nuclear compartments and chromosome positioning |
| Klaus Kaestner | Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract. |
| Jennifer Kalish | Understanding and improving detection of epigenetics and mosaicism in human disease |
| Brett Kaufman | The role of mitochondrial chromatin organization in gene expression, resistance to damage, and genome transmission. |
| Peter Klein | Early vertebrate development, Wnt signal transduction, neuropharmacology of lithium action |
| Erica Korb | Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders |
| Melike Lakadamyali | The Lakadamyali lab uses high resolution, single cell imaging technologies to investigate the link between genome organization and gene function |
| Mitchell Lazar | Regulation of gene expression and metabolism by nuclear hormone receptors. |
| Edward Lee | Neurogenerative disease pathology, genetics and epigenetics, RNA misprocessing, and human tissue transcriptomics |
| Stephen Liebhaber | Roles of chromatin structure and epigenetic controls in eucaryotic gene activation; Roles of mRNA-protein interactions in control of eucarytic mRNA stability and expression. |
| John Murray | Developmental regulatory networks, dynamics of embryonic gene expression, and single-cell methods in C. elegans |
| Vikram Paralkar | Epigenetics, Transcription, Ribosomal DNA/RNA, Bioinformatics, Hematopoiesis, Leukemia |
| John R. Pehrson | Role of histone variants in regulating chromatin structure and function |
| Kavitha Sarma | RNA interactions in epigenetic gene regulation and genome organization |
| Richard Schultz | Egg activation and gene expression in mouse embryos. |
| Sydney Shaffer | Systems biology, genomics, lineage tracing, and spatial transcriptomics applied to tissues and cancer |
| Junwei Shi | CRISPR genome editing, cancer functional genomics, transcriptional and epigenetic regulation |
| Eileen M. Shore | Genetic diseases of bone formation and development; Molecular and cell biology of bone formation and osteoblast differentiation; Transcriptional activation and regulation of bone morphogenetic protein and GNAS1 target genes. |
| Rebecca Simmons | Developmental programming of adult disease (diabetes, obesity); ß-cell development; role of epigenetics in fetal programming and early embryo/placenta development |
| Raymond Soccio | Nuclear receptors, transcription factors, lipid metabolism, genetic variation, fatty liver disease, metabolic syndrome, obesity, diabetes |
| Doris Stoffers | Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
| Kai Tan | Model gene regulatory networks in development and disease |
| Golnaz Vahedi | Epigenetics, Immunology, Human Genetics, Bioinformatics, Computational Biology, Machine-learning |
| Doris Wagner | Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues. |
| Hao Wu | Epigenomics, DNA methylation and demethylation, Transcriptional control, Single cell analysis, Stem cell biology, Neural and cardiac lineage specification and maturation |
| Kenneth Zaret | Mammalian gene regulation, cell differentiation, chromatin structure. |
| Zhaolan Zhou | Epigenetic Control of Genome Function in Brain Development and Disease |
| G&E Faculty | Brief Research Description |
|---|---|
| Montserrat Anguera |
Epigenetic mechanisms of X-Chromosome Inactivation in immune cells & immune-related diseases |
| Yoseph Barash | The lab develops machine learning algorithms that integrate high-throughput data (RNASeq, CLIPSeq , PIPSeq, etc.) to infer RNA biogenesis and function, followed by experimental verifications of inferred mechanisms. |
| Ben Black | Chromosome inheritance in somatic cells and through the germline, epigenetic and genetic contributions at mammalian centromeres, chromatin structural biochemistry and biophysics, chromatin complexes that signal errors in cell division and DNA damage during the rest of the cell cycle, chromatin assembly, mass spec-based proteomics and biophysical studies of chromosome complexes |
| Andres Blanco | I study the mechanisms by which epigenetic information is encoded, interpreted, and propagated in normal and pathological (eg. cancerous) cell identity programs. |
| Roberto Bonasio | Molecular mechanisms of epigenetic memory, Noncoding RNAs, Chromatin biochemistry |
| Maja Bucan | Genetic dissection of complex behaviors in mice; Functional genomics |
| Frederic Bushman | Virology, HIV, Poxviruses, DNA modifying enzymes, Lateral DNA transfer. |
| Brian Capell | Our lab seeks to understand how epigenetic and chromatin-based transcriptional regulatory mechanism contribute to carcinogenesis and aging, utilizing the skin as our model system. |
| Alice Chen-Plotkin | I am interested in neurogenerative diseases; my research approach uses genomic-scale screens to identify leads for downstream mechanistic follow-up in cell culture systems. |
| Sara Cherry | Genetic and mechanistic studies of viral-host interactions. |
| Robert Faryabi | Model interplay between mutated transcriptional regulators and epigenetic dysregulation in cancer |
| Michael Gandal |
The Gandal Lab has three main areas of focus: (1) gene discovery for neurodevelopmental, psychiatric disorders in large-scale biobanks; (2) developing statistical genetic tools and constructing large-scale functional genomic resources using human brain tissue samples to prioritize GWAS mechanisms; (3) using single-cell and long-read sequencing technology to characterize transcript-isoform diversity during human brain development and disease. |
| Alessandro Gardini | The Gardini lab investigates how global transcription is regulated during cell differentiation and oncogenesis using a variety of genomics and biochemistry approaches |
| Pablo Gonzalez-Camara |
The focus of the Camara lab is the application and development of computational methods to study cellular heterogeneity and its role in cancer progression |
| Struan Grant | My current work continues to primarily investigate disease genomics, with a specific focus on pediatrics |
| Hakon Hakonarson | Genetics of common and rare human diseases, using high-throughput sequencing and genotyping approaches. |
| Eric Joyce | Form and function of nuclear compartments and chromosome positioning |
| Klaus Kaestner | Using modern genetic approaches (expression profiling, gene targeting, tissue-specific and inducible gene ablation) to understand the molecular mechanisms of organogenesis and physiology of the liver, pancreas and gastrointestinal tract. |
| Rachel Kember | The lab seeks to identify the complex phenotypic and genomic interactions that lead to substance use and psychiatric disease, using computational genetics methods in electronic health record datasets linked to biobanks. |
| Erica Korb | Neuroepigenetics, chromatin biology, learning and memory, neurodevelopmental disorders |
| Edward Lee | Neurogenerative disease pathology, genetics and epigenetics, RNA misprocessing, and human tissue transcriptomics |
| John Murray | Developmental regulatory networks, dynamics of embryonic gene expression, and single-cell methods in C. elegans |
| Vikram Paralkar | Epigenetics, Transcription, Ribosomal DNA/RNA, Bioinformatics, Hematopoiesis, Leukemia |
| Jennifer Phillips-Cremins | Epigenetics | Genomics | Systems and Synthetic Bioengineering | Experimental Neuroscience | Molecular and Cellular Engineering |
| David Roos | Molecular parasitology, host-pathogen interactions, drug targets & resistance mechanisms, evolution of eukaryotic cells & organellar function, genome databases & database mining, comparative genomics, computational biology, Toxoplasma gondii, Plasmodium falciparum. |
| Sydney Shaffer | Systems biology, genomics, lineage tracing, and spatial transcriptomics applied to tissues and cancer |
| Junwei Shi | CRISPR genome editing, cancer functional genomics, transcriptional and epigenetic regulation |
| Raymond Soccio | Nuclear receptors, transcription factors, lipid metabolism, genetic variation, fatty liver disease, metabolic syndrome, obesity, diabetes |
| Doris Stoffers | Transcription factors and signal transduction; Embryonic development and adult regeneration of the endocrine pancreas; Relationship of defects in these pathways to the pathophysiology of diabetes mellitus, a disease caused by a deficiency in the production or action of insulin. |
| Kai Tan | Model gene regulatory networks in development and disease |
| Golnaz Vahedi | Epigenetics, Immunology, Human Genetics, Bioinformatics, Computational Biology, Machine-learning |
| Benjamin Voight | Using statistical genetics, population genetics, and computational biology toward understanding the biological underpinnings and evolutionary history of human phenotypes |
| Doris Wagner | Molecular mechanisms controling developmental transitions in response to environmental and endogenous cues. |
| Kai Wang | We develop genomics and bioinformatics methods to understand the genetic basis of human diseases, with specific focus on the use of long-read sequencing techniques and the integration of multimodal data from electronic health records |
| Kenneth Zaret | Mammalian gene regulation, cell differentiation, chromatin structure. |
| Zhaolan (Joe) Zhou | Epigenetic Control of Experience-dependent Gene Expression in Brain Development and Disease |
| Jun Zhu | Quorum Sensing, Bacterial pathogenesis, Biofilms, Vibrio cholerae. |
For information on how to apply for CAMB Faculty membership, please see the CAMB Bylaws.