Cell Biology, Physiology, and Metabolism Faculty
All CAMB Faculty | CB Faculty | CPM Faculty | DSRB Faculty | G&E Faculty | GTV Faculty | MVP Faculty
The Program in Cell Biology, Physiology, and Metabolism is dedicated to training graduate students in the diversity of medical science that defines modern cell biology, as well as providing ample time and resources for specializations.
Current Members
Cell Biology, Physiology and Metabolism
Click the faculty member's name to see more detailed information.
Faculty
Laboratories in this program conduct research in a wide variety of areas that encompass, but are not limited to, five overlapping areas of research:
- Cellular Metabolism
- Cell Motility, The Cytoskeleton, and Muscle Physiology
- Intracellular Trafficking and Organelle Function
- Membrane Transport
- Signal Transduction
Faculty | Brief Research Description |
---|---|
Zoltan Pierre Arany | Cardiovascular metabolism |
Joseph A. Baur | Molecular mechanisms of aging |
Joshua Dunaief | Retinal iron trafficking and its role in retinal disease |
J. Kevin Foskett | Ion channels, calcium signaling, cystic fibrosis. |
Daniel Kelly | Transcriptional and epigenetic control of mitochondrial function; nuclear receptor signaling in the developing and diseased heart; molecular mechanisms controlling muscle metabolic fitness. |
Mitchell Lazar | Regulation of gene expression and metabolism by nuclear hormone receptors. |
Robert Lee | Epithelial ion and fluid transport, calcium/cAMP/nitric oxide signaling, extra-oral taste receptors, respiratory mucociliary transport and innate immunity, respiratory physiology and pathophysiology, chronic rhinosinusitis, cystic fibrosis |
Virginia Lee | Tau, a-synuclein and amyloid beta precursor protein (APP), and their roles in the pathobiology of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson’s disease (PD), and frontotemporal dementias (FTD). |
Benjamin L. Prosser | cardiac electrophysiology; excitation-contraction coupling; calcium signaling; mechanotransduction; redox signaling |
Paul Titchenell | Molecular mechanisms of insulin signaling and insulin resistance |
Faculty | Brief Research Description |
---|---|
Erfei Bi | Development of cell polarity and control of cytokinesis in budding yeast. |
Janis Burkhardt | Regulation and function of the T cell cytoskeleton. |
Peter Davies | Biomechanics in Vascular Biology/Pathology, Hemodynamics and Atherosclerosis, Vascular Cell Communication, Cytoskeletal and membrane biophysics. |
Horace M. DeLisser | Endothelial Cell Adhesion and Motility. |
Dennis Discher | Cell and nuclear membrane structure-function; Adhesion mechanisms and responses of cells; Phagocyte recognition processes; Membrane skeleton and cytoskeleton; Diseases ranging from muscular dystrophy to anemias to athersclerosis; Drug delivery. |
Yale Goldman | Relating the structural changes to enzymatic reactions and mechanical steps of the energy transduction mechanism by mapping the real-time domain motions of the motor proteins and ribosomal elongation factors. |
Ekaterina L. Grishchuk | Mechanisms that drive and control chromosome motions in mitosis |
Wei Guo | The molecular basis for polarized exocytosis and how exocytosis contributes to polarized cell growth and morphogenesis. |
Erika L. Holzbaur | Microtubule-based motility. |
Paul Janmey | Cytoskeleton, phosphoinositide signalling, cell mechanics. |
Anna S. Kashina | Protein modifications, mouse genetics, cancer, cytoskeleton, cardiovascular development, angiogenesis. |
Frank Luca | Yeast and mammalian cell cycle regulation; Cytokinesis. Daughter cell-specific gene expression; Polarized growth. Mitotic Exit Network (MEN); Regulation of Ace2-dependent transcription and Morphogenesis (RAM). |
Michael Ostap | Molecular mechanisms of cell motility. |
Benjamin Prosser | Mechano-signaling in heart |
Tatyana Svitkina | Roles of the cytoskeleton in cell motility. |
Phong Tran | The cytoskeleton and cellular pattern formation. |
John W. Weisel | Intermolecular and cellular interactions in blood clotting, fibrinolysis, and atherosclerosis studied by molecular biophysical methods. |
Faculty | Brief Research Description |
---|---|
Zoltan Pierre Arany | cardiovascular metabolism |
Yair Argon | Functions of molecular chaperones in the immune system - modulation of antigen receptors expression and of peptide presentation. |
Joseph A. Baur | Molecular mechanisms of aging |
Erfei Bi | Development of cell polarity and control of cytokinesis in budding yeast. |
Natali Chanaday | Molecular mechanisms of neuronal communication |
Margaret Chou | Mechanisms of malignant transformation; signaling by small GTPases; regulation of vesicular trafficking; ubiquitination. |
Andy Dancis | Iron transport into mitochondria, Heme synthesis, Fe-S cluster biogenesis, Yeast genetics, and Sideroblastic anemia |
Carol Deutsch | Function and assembly of potassium channels in human T lymphocytes. |
Robert Doms | HIV; Emerging viral pathogens; Cell biology of Alzheimer's disease. |
J. Kevin Foskett | Ion channels, calcium signaling, cystic fibrosis. |
Claudio Giraudo | The research of the laboratory is mainly focused on understanding the membrane trafficking events and fusion machinery involved in cytotoxic immune response. Additionally, we also study the influence of membrane lipid composition on protein sorting. |
Yale Goldman | Relating the structural changes to enzymatic reactions and mechanical steps of the energy transduction mechanism by mapping the real-time domain motions of the motor proteins and ribosomal elongation factors. |
Wei Guo | The molecular basis for polarized exocytosis and how exocytosis contributes to polarized cell growth and morphogenesis. |
Erika L. Holzbaur | Microtubule-based motility. |
Paul Janmey | Cytoskeleton, phosphoinositide signaling, cell mechanics. |
Anna S. Kashina | Protein modifications, mouse genetics, cancer, cytoskeleton, cardiovascular development, angiogenesis. |
Frank Luca | Yeast and mammalian cell cycle regulation; Cytokinesis. Daughter cell-specific gene expression; Polarized growth. Mitotic Exit Network (MEN); Regulation of Ace2-dependent transcription and Morphogenesis (RAM). |
Michael S. Marks | Regulation and diseases of intracellular protein transport and organelle biogenesis. |
Michael Ostap | Molecular mechanisms of cell motility. |
Mechthild Pohlschroder | Prokaryotic protein translocation across hydrophobic membranes. |
Faculty | Brief Research Description |
---|---|
Natali Chanaday |
Molecular mechanisms of neuronal communication |
Carol Deutsch | Function and assembly of potassium channels in human T lymphocytes. |
Josuha Dunaief | Retinal iron trafficking and its role in retinal disease |
J. Kevin Foskett | Ion channels, calcium signaling, cystic fibrosis. |
Robert Lee | Epithelial ion and fluid transport, calcium/cAMP/nitric oxide signaling, extra-oral taste receptors, respiratory mucociliary transport and innate immunity, respiratory physiology and pathophysiology, chronic rhinosinusitis, cystic fibrosis |
Zhe Lu | Molecular and biophysical mechanisms of ion channels. |
Minghong Ma | Neurobiology of the sense of smell |
Dejian Ren | Regulation of cellular excitability by ion channels and calcium signaling. |
Faculty | Brief Research Description |
---|---|
Yair Argon | Functions of molecular chaperones in the immune system - modulation of antigen receptors expression and of peptide presentation. |
Lawrence F. Brass | Mechanisms of thrombosis. |
Janis Burkhardt | Regulation and function of the T cell cytoskeleton. |
Natali Chanaday |
Molecular mechanisms of neuronal communication |
Margaret Chou | Mechanisms of malignant transformation; signaling by small GTPases; regulation of vesicular trafficking; ubiquitination. |
Dennis Discher | Cell and nuclear membrane structure-function; Adhesion mechanisms and responses of cells; Phagocyte recognition processes; Membrane skeleton and cytoskeleton; Diseases ranging from muscular dystrophy to anemias to athersclerosis; Drug delivery. |
J. Kevin Foskett | Ion channels, calcium signaling, cystic fibrosis. |
Paul Janmey | Cytoskeleton, phosphoinositide signalling, cell mechanics. |
Mark Kahn | Signaling pathways in angiogenesis and hemostasis. |
Michael Lampson | Mitotic kinase signaling, chromosome segregation in mitosis and meiosis, kinetochore function. |
Robert Lee | Epithelial ion and fluid transport, calcium/cAMP/nitric oxide signaling, extra-oral taste receptors, respiratory mucociliary transport and innate immunity, respiratory physiology and pathophysiology, chronic rhinosinusitis, cystic fibrosis |
Paul Titchenell | Molecular mechanisms of insulin signaling and insulin resistance |
Rebecca Wells | TGF-ß receptor biology; Hepatic stellate cell function in liver fibrosis. |
For information on how to apply for CAMB Faculty membership, please see the CAMB Bylaws.